JP2006296351A - Insect-proof agent - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an insect-proof agent exhibiting high insect-proof efficacy, clearly indicating the end poind of use because the evaporation of a room temperature-evaporating chemical and sublimation of a sublimable substance are completed in nearly the same period and having excellent productivity. <P>SOLUTION: The insect-proof agent is obtained as follows. A chemical carrier prepared by supporting 0.5-2.0 wt.% of one or two or more kinds of room temperature-evaporating chemicals selected from empenthrin, transfluthrin, profluthrin and metofluthrin on the sublimable substance is housed in a flexible bag. Both surfaces or one surface of the bag is Japanese paper or a nonwoven fabric having 10-50 g/m<SP>2</SP>weight in which the inner surface is laminated to a chemical-permeable film having 10-30 μm wall thickness or a filament nonwoven fabric having 10-50 g/m<SP>2</SP>weight and produced by a lamination extending method. In the case of the one surface, the other surface is formed of a chemical-impermeable film. The insect-proof agent is composed as follows. Even when the chemical carrier contracts with sublimation of the sublimable substance, at least a part of the chemical carrier comes into contact with the inner surface of the flexible bag. The end point of use can be recognized by visually observing the disappearing state of the chemical carrier. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

The present invention relates to an improvement of an insect repellent in which a drug carrier formed by supporting a room temperature volatile drug on a sublimable substance is housed in a flexible bag.

Conventionally, as insect repellents for clothes, solid paradichlorobenzene, naphthalene, camphor and other sublimable insect repellents, and liquid room-temperature volatile chemicals such as empentrin are impregnated in a carrier such as paper or plastic and stored in a container. Insect repellents are known.
The former sublimable insect repellent has a weak effect on clothing pests such as moths and chickworms, and is problematic in terms of toxicity and environmental pollution. On the other hand, room temperature volatile pyrethroids such as empentrin have higher insect repellent power than the former sublimable insect repellent, and show a repellent effect in a small amount, but in a form impregnated on a carrier such as paper or plastic, There is no change in appearance even at the end of efficacy, and the end point of use cannot be clearly recognized.

In view of this, there has been a proposal that a liquid room temperature volatile chemical such as empentrin is supported on a sublimable substance and the disappearance of the sublimable substance is used as an indicator. For example, Japanese Patent Application Laid-Open No. 61-83102 discloses an oil-based insect repellent such as empentrin contained in a molding substrate of a sublimable substance such as paradichlorobenzene or naphthalene and packaged with breathable Japanese paper. Yes. However, in this case, since the drug diffuses through the breathable Japanese paper without restriction, the insect repellent effect does not last long. JP-A-7-285805 discloses a tablet comprising a combination of a room temperature volatile drug and a sublimable substance, part of which is made of a transparent resin film, and the other part is a breathable material such as nonwoven fabric or paper, and Disclosed is an insect pest for clothing pests housed in a packaging container made of a breathable material having a gas permeation suppressing layer formed on a part of its inner surface. This insect repellent is intended so that the end of volatilization of the room temperature volatile chemical and the end of sublimation of the sublimable substance are almost simultaneously, but as shown in the Examples, (4,6-triisopropyl-1,3,5-trioxane) The content of empentrin is high, and even if a non-woven fabric with a large basis weight is used, there is an unavoidable risk of oozing out of the drug. It is also difficult to adjust the sublimation speed. Furthermore, it is necessary to form a gas permeation suppression layer on a part of the inner surface of the air-permeable material, and the structure is complicated and there are problems in manufacturability.
JP 61-83102 A Japanese Patent Laid-Open No. 7-285805

The present invention has a high insect repellent effect, and since the volatilization of the room temperature volatile chemical and the sublimation of the sublimable substance are completed almost simultaneously, the end point of use is clear, and an insect repellent excellent in productivity is obtained. The purpose is to provide.

In order to solve the above problems, the present invention employs the following configuration.
(1) A flexible drug carrier formed by supporting 0.5 to 2.0% by weight of a sublimable substance with one or two kinds of room temperature volatile drugs selected from empentrin, transfluthrin, profluthrin, and metfurthrin. In the insect repellent housed in a pouch, the flexible bag is a Japanese paper or non-woven fabric having a basis weight of 10 to 50 g / m ² , wherein both sides or one side of the flexible bag are internally laminated with a drug permeable film having a thickness of 10 to 30 μm, or A non-woven fabric having a basis weight of 10 to 50 g / m ² manufactured by a laminate spreading method. In the case of one side, the other side is formed of a drug-impermeable film, and the drug carrier is used for sublimation of the sublimable substance. Even if the size is reduced, at least a part of the drug carrier is in contact with the inner surface of the flexible bag, and the end point of use can be recognized by observing the disappearance state of the drug carrier. Insect repellent you.
(2) The insect repellent according to (1), wherein both surfaces of the flexible bag are Japanese paper or non-woven fabric having a basis weight of 10 to 50 g / m ² laminated with a drug-permeable film having a thickness of 10 to 30 μm.
(3) The insect repellent according to (1) or (2), wherein the room temperature volatile chemical is profluthrin or metfurthrin.
(4) The insect repellent according to any one of (1) to (3), wherein the sublimable substance is 2,4,6-triisopropyl-1,3,5-trioxane or adamantane.

The insect repellent of the present invention has a high insect repellent effect, and the end-point display of use is clear because the volatilization of the room temperature volatile chemical and the sublimation of the sublimable substance are completed almost simultaneously, and it is excellent in productivity. Therefore, its practicality is extremely high.

The room-temperature volatile drug used in the present invention is one or two selected from empentrin, transfluthrin, profluthrin and metfurthrin. These pyrethroid compounds have a higher vapor pressure than conventional allethrin, flamethrin and praretrin, and are superior to insect pests such as moss, flies, flyfish and chironomid as well as insect pests and insecticides such as moss, swordfish, and chironomid Shows efficacy. Of course, in the acid or alcohol component of the compound, when there are optical isomers and geometric isomers based on asymmetric carbon, these and any mixtures thereof are also included in the present invention.
In particular, profluthrin and metfurthrin, which are more effective in terms of insecticidal and insecticidal effects and are excellent in chemical stability, are suitable for the insecticide of the present invention.

In the present invention, as long as it does not interfere with the volatilization of the room temperature volatile chemical, other insecticides, insect repellent components, repellent components, antibacterial components, antifungal components, deodorant components, aromatic components, etc. that have excellent volatility Can be blended. For example, antibacterial ingredients such as hinokitiol, tetrahydrolinalol, eugenol, citronellal, allyl isothiocyanate, antifungal ingredients such as isopropylmethylphenol, orthophenylphenol, citronella oil, orange oil, lemon oil, lime oil, yuzu oil, lavender oil, Peppermint oil, eucalyptus oil, jasmine oil, camellia oil, green tea essential oil, limonene, α-pinene, linalool, geraniol, phenylethyl alcohol, amyl cinnamamic aldehyde, cumin aldehyde, benzyl acetate and other aromatic components, “green fragrance” And a fragrance ingredient containing green leaf alcohol and green leaf aldehyde.

In the present invention, a sublimable substance is used as a carrier for the room temperature volatile drug. Examples of sublimable substances include 2,4,6-triisopropyl-1,3,5-trioxane [trade name: Sunsaburi (manufactured by Ogawa Fragrance Co., Ltd.)], adamantane, tricyclododecane [trade name: Aisawa D (Idemitsu Oil Co., Ltd.). Chemical Co., Ltd.)], 2-hydroxycamphor (common name: borneol), 2,2-dimethyl-1,3-propanediol (common name: neopentyl glycol), among others, 2,4 , 6-Triisopropyl-1,3,5-trioxane and adamantane are easy to use.

In the present invention, the loading amount of the room-temperature volatile drug with respect to the sublimable substance (usually 0.5 to 8 g, preferably 1 to 4 g) is set to 0.5 to 2.0% by weight. If the loading amount is less than 0.5% by weight, the durability of the insect repellent effect may be insufficient. On the other hand, if the loading amount exceeds 2.0% by weight, it spreads into the Japanese paper or non-woven fabric containing the drug carrier. In order to prevent this, if the weight of the Japanese paper or the nonwoven fabric is excessively increased, it is difficult to control the volatilization of the room temperature volatile chemical and the sublimation of the sublimable substance.
The shape of the sublimable substance is arbitrary, but tablets formed into a plate shape, a rod shape, a disk shape, a donut shape, etc. are common.
As a method for supporting a room temperature volatile chemical, a sublimable substance may be impregnated with a solvent, a surfactant, a dispersant, or the like, if necessary, or a mixture of a chemical and a sublimable substance. It can be cooled after melting, or formed into a tablet using a pressurizer.

A stabilizer, a colorant, an antistatic agent, and the like may be appropriately blended in the drug carrier of the present invention. The addition of color is preferable because it not only increases the commercial value but also makes it possible to clearly see the end point of volatilization of the room temperature volatile chemical.

In addition, a substance other than a sublimable substance can be used as a part of the carrier. Examples thereof include cellulosic carriers such as paper, pulp and viscose, synthetic resin carriers such as ethylene-vinyl acetate resin, polyester and olefin polymer, and inorganic carriers such as calcium silicate. However, these carriers are involved only in the volatilization of the drug, and of course the display function is left to the sublimable substance.

The present invention is a Japanese paper or non-woven fabric having a basis weight of 10 to 50 g / m ² laminated on both sides with a drug permeable film having a wall thickness of 10 to 30 μm, or a basis weight of 10 to 50 g / m manufactured by a laminate spreading method. ^{2 is} a long-fiber nonwoven fabric, and in the case of one side, the other side is housed in a flexible bag formed of a drug-impermeable film, and the drug carrier is used for sublimation of the sublimable substance. Even if the size is reduced, at least a part of the drug carrier is in contact with the inner surface of the Japanese paper or nonwoven fabric in the flexible bag.
That is, the loading amount of the specified room temperature volatile drug with respect to the sublimation substance is set to 0.5 to 2.0% by weight, and the basis weight of the flexible bag for storing this and the thickness range of the laminate film are set. By combining, it is possible to adjust the end of volatilization of the room temperature volatile chemical and the end of sublimation of the sublimable substance almost at the same time, thereby achieving a clear use end point display function.

As the material of the Japanese paper or the nonwoven fabric, any material can be used as long as it can be impregnated and diffused with a room temperature volatile chemical leached from a sublimable substance. However, if the basis weight of the Japanese paper or non-woven fabric is less than 10 g / m ² , the migration and diffusion of the room temperature volatile chemical leached onto the surface of the sublimable substance to the Japanese paper or non-woven fabric is not sufficient, and the volatilization efficiency of the room temperature volatile chemical Is lower than the sublimation efficiency of the sublimable substance, and it becomes difficult to adjust the end of volatilization of the room temperature volatile chemical and the end of sublimation of the sublimable substance almost simultaneously.
On the other hand, even when the basis weight of Japanese paper or non-woven fabric exceeded 50 g / m ² , it was recognized that there were difficulties in volatilization of the room temperature volatile chemical and sublimation control of the sublimable substance. In addition, the flexibility is impaired, or the opacity increases and the disappearance of the sublimable substance is difficult to visually recognize from the outside, which does not meet the object of the present invention.

As the material of the drug permeable film laminated on the inner surface of Japanese paper or non-woven fabric, polyolefin such as polyethylene (PE) and polypropylene (PP), or ethylene vinyl acetate (EVA) is suitable, and the wall thickness is 10 to 30 μm. Is specified in the range.
That is, if it is out of this range, the volatilization of the room temperature volatile drug and the sublimation control of the sublimable substance are not successful, and the excellent effect of the present invention is that the amount of the room temperature volatile drug on the sublimable substance and the drug carrier This is achieved only by combining the basis weight of the Japanese paper or nonwoven fabric of the flexible bag to be stored and the thickness range of the laminate film.

Moreover, in this invention, the 10-50 g / m < ² > long-fiber nonwoven fabric manufactured by the lamination | stacking extending | stretching method can also be used as a raw material of the both surfaces or single side | surface of a flexible bag.
For example, Teijin's long-fiber nonwoven fabric (trade name: Melfit), which has a multilayer structure of special polyester and special polypropylene, can be used, and has excellent breathability and heat sealability.

When one side of the flexible bag is the Japanese paper, non-woven fabric or long-fiber non-woven fabric, the other side may be formed of a drug-impermeable film. Here, examples of the drug-impermeable film include polyester (PET, PBT, etc.), polyamide, polyacetal, polyacrylonitrile and the like, and the thickness thereof is determined within a range that does not impair flexibility. Further, the film may be colored or printed in order to impart design and character properties.
Then, usually, both surfaces are bonded by means such as heat sealing to produce a flexible bag.

Although the usage-amount of the insect repellent of this invention can be suitably determined according to a use period, the width of the space for control, etc., for example, in the case of 6 months, about 10-200 mg of room temperature volatile chemicals per 50L of drawers. What is necessary is just to make it contain in a sublimation substance.

The insect repellent of the present invention thus obtained can be used in large space storage facilities such as chests, costume boxes, closets and walk-in closets, and clothing pests such as moths, moths, swordworms, and mosquitoes, mosquitoes, moths, flies. Excellent insecticidal and insecticidal effects against various pests such as chironomid. And since the replacement | exchange time of a chemical | medical agent support body can be easily recognized only by visually observing the disappearance state of a chemical | medical agent support body, it is very useful and practical.

Next, the insect repellent of the present invention will be described in more detail based on specific examples and test examples.

FIG. 1 shows a cross-sectional view of an embodiment of the insect repellent of the present invention (both sides of a flexible bag are Japanese paper).
The insect repellent 1 is obtained by storing a drug carrier 2 in which a room temperature volatile drug is supported on a sublimable substance in a flexible bag 3, and the flexible bag 3 is a drug laminated on Japanese paper 4 and the inner surface thereof. The transparent film 5 is comprised.
In this example, 20 mg of profluthrin, which is a room-temperature volatile drug, was loaded on 2.0 g of disc-shaped sunsably (colored blue) with a thickness of 7 mm (the amount of drug supported on the sublimable substance: 1.0). %) 2 was prepared, and the two were designed in a drawer with a volume of about 50 L and used for one year. Moreover, the weight of Japanese paper was 20 g / m ² , and the thickness of polyethylene used for the inner surface laminate was 15 μm.

This insect repellent 1 was used by putting it in a drawer of clothes containing clothes. Over the course of one year, there was no damage from clothing pests and no problems such as bleeding on clothing were observed. In addition, the blue sunsably gradually decreased with the progress of use, and all disappeared after about one year. This insect repellent 1 was very practical because it was easy to use and the end point display was clear.

FIG. 2 shows a cross-sectional view of another embodiment of the insect repellent of the present invention (one side of a flexible bag is Japanese paper and the other side is a drug-impermeable film).
One side of the flexible bag 3 is composed of Japanese paper 4 and a drug permeable film 5 laminated on the inner surface thereof, while the other side is a drug impermeable polyester film 6.
In this example, empentrin 120 mg, which is a room temperature volatile chemical, was loaded on 10 g of disc-shaped sunsably (colored blue) 7 g in thickness (the amount of drug supported on the sublimable substance: 1.2%). No. 2 was prepared, and the four pieces were put in a clothes chiffon having a volume of about 800 L and designed to be used for one year. Moreover, the basis weight of Japanese paper was 25 g / m ² , and the thickness of polyethylene used for the inner surface lamination was 12 μm.

This insect repellent 1 was hung on a clothes chiffon and used for one year. Meanwhile, clothing can be completely protected from clothing pests, and after about one year, the remaining amount of empentrin and sansaburi are both small, and it is recognized that it has an excellent end point display function. It was.

According to Example 1, various drug carriers 2 and flexible bags 3 shown in Table 1 were prepared. Table 2 shows the results of the volatilization test conducted in a 50 L costume box at 25 ° C. In addition, the residual amount with the passage of time of a room temperature volatile chemical | medical agent and a sublimable substance was shown by the relative ratio with respect to an initial value.

The insect repellent of the present invention has an excellent end point display function according to the present invention, because the volatilization of the room temperature volatile chemical and the sublimation of the sublimable substance proceed almost in parallel over the course of one year, and both of them are completed almost simultaneously. Was confirmed.
On the other hand, as in Comparative Examples 1 and 2, when the loading amount of the room-temperature volatile chemical with respect to the sublimable substance exceeded 1.5%, oozing into the Japanese paper or the nonwoven fabric was inevitable. In the case of Comparative Example 3 in which the amount of Japanese paper is increased, the problem of bleeding is somewhat improved, but the volatilization of the room temperature volatile chemical and the sublimation control of the sublimable substance become difficult, and the opacity increases and the sublimation property increases. The disappearance of the substance became difficult to see. On the other hand, as in Comparative Example 4, when the basis weight of the Japanese paper is less than 10 g / m ² , the room temperature volatile chemical that has exuded on the surface of the sublimable substance is not sufficiently transferred and diffused to the Japanese paper, and the room temperature volatile chemical is used. The volatilization efficiency was lower than the sublimation efficiency of the sublimable substance. Furthermore, as in Comparative Examples 5 and 6, if the thickness of the permeable film laminated on the inner surface of the Japanese paper is out of the range of 10 to 30 μm, the volatilization of the room temperature volatile chemical and the sublimation control of the sublimable substance will not be successful. It did not meet the purpose of the present invention.

Sectional drawing of one Example of the insect repellent of this invention is shown. Sectional drawing of the other Example of the insect repellent of this invention is shown.

Explanation of symbols

1: insect repellent 2: drug carrier 3: flexible bag 4: Japanese paper 5: drug permeable film 6: drug impermeable film

Claims (4)

A flexible carrier having a drug-carrying body in which 0.5 to 2.0% by weight of one or two room-temperature volatile drugs selected from empentrin, transfluthrin, profluthrin and metfurthrin are supported on a sublimable substance. In the stored insect repellent, the flexible bag is a Japanese paper or a nonwoven fabric having a basis weight of 10 to 50 g / m ² , in which both sides or one side of the flexible bag are internally laminated with a drug permeable film having a thickness of 10 to 30 μm, or a laminated spreading method 10-50 g / m ² long-fiber nonwoven fabric manufactured by the method, in the case of one side, the other side is formed of a drug-impermeable film, and the drug carrier shrinks with sublimation of the sublimable substance. However, at least a part of the drug carrier is in contact with the inner surface of the flexible bag so that the end point of use can be recognized by observing the disappearance state of the drug carrier. Insect repellent, characterized in that. The insect repellent according to claim 1, wherein both surfaces of the flexible bag are Japanese paper or non-woven fabric having a basis weight of 10 to 50 g / m ² laminated with a drug permeable film having a wall thickness of 10 to 30 µm. The insect repellent according to claim 1 or 2, wherein the room temperature volatile chemical is profluthrin or metfurthrin. The insect repellent according to any one of claims 1 to 3, wherein the sublimable substance is 2,4,6-triisopropyl-1,3,5-trioxane or adamantane.

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