JP2006282618A - Poison bait for agricultural and horticultural use - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a poison bait for agricultural and horticultural use exhibiting excellent controlling effect against various harmful insects. <P>SOLUTION: The poison bait for agricultural and horticultural use contains an edible carrier (e.g. rice bran) attracting harmful insects and a hydrazine carboxamide compound expressed by chemical formula (1) as active component. In the chemical formula (I), A is a group expressed by chemical formula (2) (R<SP>5</SP>is a hydrogen atom or a 1-6C alkyl; and Y groups may be the same or different and are one or two substituents selected from halogen atoms and 1-6C haloalkyl groups); R<SP>1</SP>is a hydrogen atom; R<SP>2</SP>is a hydrogen atom; R<SP>3</SP>is a hydrogen atom or the like; R<SP>4</SP>may be the same or different and is a hydrogen atom, a substituted phenyl group, etc. having one or two substituents selected independently from halogen atoms, cyano group or the like; X is a halogen atom, cyano group, a 1-6C haloalkyl group or a 1-6C haloalkoxy group; and Y is S or O. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to an agricultural and horticultural poison bait containing a hydrazine carboxamide compound as an active ingredient, a method for using the same, and a method for controlling agricultural and horticultural pests.

Conventionally, as an agricultural and horticultural poison bait, a carrier that is an attracting ingredient (rice bran, etc.) containing an organophosphorus insecticide, a carbamate insecticide and a pyrethroid insecticide as an active ingredient, It is used for controlling crickets and the like (for example, see Patent Document 1).
The hydrazine carboxamide compound used in the present application is a known compound having insecticidal activity (see, for example, Patent Document 2). It is known that it can be used by adjusting to an appropriate dosage form according to the purpose of use, and can also be used as a bait agent (poison bait) for stored grain pests, house pests, sanitary pests, forest pests, and the like. Use of the same compound as an ant control agent, use for controlling ectoparasites for animals, and the like are known (see, for example, Patent Document 3 or 4). In addition, it is also known to use a powder formulation for controlling white ants (see, for example, Patent Document 5). However, there is no description or suggestion about their use as poisonous baits for agriculture and horticulture.
It is already known that hydrazine carboxamide and various compounds are sodium channel blockers (see, for example, Patent Document 6). As other sodium channel blockers, various compounds such as pyrazoline compounds are known (for example, see Non-Patent Document 1 or Patent Document 6).

JP 62-126006 A JP-A-5-4958 JP 2001-72516 A JP 2002-128614 A JP 2004-285061 A

JP-T-2004-521888 Forefront of New Pesticide Development -Development to Biocontrol Science- (CMC Publishing Co., Ltd.) (Chapter 3 Trends of Insecticides, 5 Pyrazoline Agents p.94-p.96)

Organic phosphorous agents and carbamate agents have various problems as active ingredients of agricultural and horticultural poison baits. These drugs are not sufficiently stable in outdoor natural conditions such as fields of the compound itself, and the effect persistence is short. The target pests avoid poisonous baits due to their unique odor, so the drugs are not taken up sufficiently. The effect is not always sufficient because of the emergence of resistant pests. Because it is highly toxic to other animals such as mammals and birds, there is a risk of accidents due to accidental intake of poisonous baits. Pyrethroid agents also have various problems. Since the pyrethroid agent is repellent to pests, the drug is not sufficiently taken up as a poison bait, and sufficient lethality cannot be obtained. Resistance pests have appeared and the effect is not always sufficient. In addition, it is highly toxic to fish and difficult to use around rivers and other water systems.
Therefore, in order to protect agricultural and horticultural crops from pests etc. that inhabit soil etc., there is no repellent effect on pests, etc., it maintains a high effect at low doses, and it also has a high effect on pests that are resistant to existing drugs There has been a need for an agricultural and horticultural poison bait that is low in toxicity to organisms other than the target pests such as mammals, birds and fish.

〔式中、Ａは In order to solve the above problems, the present inventors incorporated a hydrazine carboxamide compound as an active ingredient in a carrier that attracts pests. The present inventors have found that a high pest control effect is exhibited even when the application amount is extremely low, and the present invention has been completed. Moreover, the horticultural poisonous bait containing hydrazine carboxamide was found to have excellent incentive and eating habits against various pests (no repellency). It was also found that it has a high lethal effect against various pests including pests resistant to existing drugs, and the high utility of the present invention could be confirmed. Furthermore, we have found that these characteristics are common to sodium channel blockers.
That is, the present invention provides a general formula (I) that is a sodium channel blocker as a carrier attracting pests:

[Where A is

（式中、Ｒ⁵は水素原子又はC₁-C₆アルキル基を示し、Ｙは同一又は異なっても良く、ハロゲン原子及びハロC₁-C₆アルキル基から選択される１〜２個の置換基を示す。）又は

(Wherein R ⁵ represents a hydrogen atom or a C ₁ -C ₆ alkyl group, Y may be the same or different, and _one or two substituents selected from a halogen atom and a halo C ₁ -C ₆ alkyl group) Group) or

Wherein R ⁵ and Y are the same as above, and R ⁶ is selected from a hydrogen atom, a C ₁ -C ₆ alkylcarbonyl group, a phenylcarbonyl group, or a C ₁ -C ₆ alkyl group which may be the same or different. A substituted phenylcarbonyl group having 1 to 2 substituents is shown.).
R ¹ represents a hydrogen atom, a C ₁ -C ₆ alkyl group or a C ₁ -C ₃ alkoxycarbonyl group. R ² represents a hydrogen atom, a hydroxyl group, a C ₁ -C ₆ alkyl group, a C ₁ -C ₆ alkoxy group, a C ₁ -C ₆ alkylcarbonyl group or a phenylcarbonyl group, and R ² together with Y It represents a methylene group and can form an indane ring. R ³ represents a hydrogen atom, a hydroxyl group, a C ₁ -C ₆ alkyl group, a C ₁ -C ₆ alkoxy group, a C ₁ -C ₆ alkylcarbonyl group or a phenylcarbonyl group, and R ³ together with R ⁵ A hetero 5-membered ring or a hetero 6-membered ring containing at least two nitrogen atoms, and the hetero 6-membered ring can contain one oxygen atom. R ⁴ may be the same as or different from a hydrogen atom, and represents a substituted phenyl group having 1 to 2 substituents selected from a halogen atom, a nitro group and a cyano group, or a C ₁ -C ₃ alkoxycarbonyl group. X is a halogen atom, cyano group, halo C ₁ -C ₆ alkyl group, halo C ₁ -C ₆ alkoxy group, halo C ₁ -C ₆ alkylthio group, halo C ₁ -C ₆ alkylsulfinyl group or halo C ₁ -C _{6 represents} an alkylsulfonyl group. W represents an oxygen atom or a sulfur atom. ]
Agro-horticultural poisonous bait comprising the hydrazine carboxamide compound represented by the formula: Is something to do.

The present invention is a technique that can significantly reduce the amount of applied hydrazine carboxamide compound per unit area. The poisonous bait for agricultural and horticultural use according to the present invention exhibits an excellent effect even at a dose of about 1/20 of the hydrazine carboxamide compound compared with a general agricultural chemical preparation in an application amount per unit area. In addition, hydrazine carboxamide compounds are excellent in environmental stability. It is clearly superior to the conventional agricultural and horticultural poison baits in terms of sustained effect.
The agricultural and horticultural poison bait of the present invention exhibits excellent effects on various pests that are resistant to conventional insecticides and the like. Furthermore, it is a poisonous bait for agriculture and horticulture that is superior to conventional products in terms of safety to other animals such as mammals, birds and fish. The poison bait according to the present invention has the advantage that the amount of the drug remaining on the crop is reduced compared to the case where it is normally sprayed on the crop, and also meets the demand for reducing agricultural chemicals.

In the definition of the general formula (I) of the hydrazine carboxamide compound of the present invention, “halogen atom” means chlorine atom, bromine atom, iodine atom or fluorine atom, and “C ₁ -C ₆ alkyl group” means, for example, methyl Linear or branched group such as group, ethyl group, n-propyl group, i-propyl group, n-butyl group, i-butyl group, s-butyl group, t-butyl group, n-pentyl group, n-hexyl group A branched alkyl group having 1 to 6 carbon atoms is shown. “N-” represents normal, “i-” represents iso, “s-” represents secondary, and “t-” represents tertiary. The “halo C ₁ -C ₆ alkyl group” is the same as, for example, a trifluoromethyl group, a pentafluoroethyl group, a 1,2,2,2, -tetrafluoro-1- (trifluoromethyl) ethyl group, or the like. A linear or branched alkyl group having 1 to 6 carbon atoms substituted with one or more halogen atoms which may be different is shown. “Halo C ₁ -C ₆ alkoxy group” means, for example, the number of straight or branched carbon atoms substituted by one or more halogen atoms which may be the same or different, such as a trifluoromethoxy group, a difluoromethoxy group, etc. 1-6 alkoxy groups are shown.
Further, the hydrazine carboxamide compound has geometric isomers based on a carbon-nitrogen double bond, that is, (E) isomer and (Z) isomer, and the present invention includes each of these geometric isomers alone and in a mixture of any ratio. It is a waste. In some cases, optical isomers exist, and these optical isomers alone and a mixture in an arbitrary ratio are included.

（式中、Ｒ⁵が水素原子又はC₁-C₆アルキル基を示し、Ｙは同一又は異なっても良く、ハロゲン原子又はハロC₁-C₆アルキル基から選択される１個の置換基を示す。特に好ましいＹは３−クロロ基又は３−トリフルオロメチル基である。）であり、
Ｒ¹としては水素原子であり、Ｒ²としては水素原子、C₁-C₆アルキル基、C₁-C₆アルコキシ基等であり、又、Ｒ²がＹと一緒になってメチレン基を示してインダン環を形成する場合も好ましい。Ｒ³としては水素原子、C₁-C₆アルコキシ基等が好ましい。又、Ｒ³がＲ⁵と一緒になって少なくとも２個の窒素原子を含むヘテロ６員環を形成し、該へテロ６員環には１個の酸素原子を含む場合が好ましく、特に１，３，４−オキサジアジン環を形成する場合が好ましい。Ｒ⁴としては同一又は異なっても良く、ハロゲン原子、ニトロ基又はシアノ基から選択される１個の置換基を有する置換フェニル基又はC₁-C₃アルコキシカルボニル基が好ましい。特に好ましいＲ⁴としては、４−シアノフェニル基又はメトキシカルボニル基である。Ｘとしてはハロゲン原子、ハロC₁-C₆アルキル基、ハロC₁-C₆アルコキシ基、ハロC₁-C₆アルキルチオ基が好ましい。Ｗとしては酸素原子が好ましい。
特に好ましい化合物としては4-{2-({[4-(trifluoromethoxy)anilino]carbonylhydrazono)-2-[3-(trifluoromethyl)phenyl]ethylbenzonitrile（2-E、2-Zmixture）（ＣＡＳ名）（ＣＡＳ登録番号139968-49-3）メタフルミゾン（ＩＳＯ名、開発コードＢＡＳ−３２０Ｉ又はＮＮＩ−０２５０、以下「化合物Ａ」という。）、methyl (S)-N-[7-chloro-2,3,4a,5-tetrahydro-4a-(methoxycarbonyl)indeno[1,2-e][1,3,4]oxadiazin-2-ylcarbonyl]-4'-(trifluoromethoxy)carbanilate （ＩＵＰＡＣ名）が挙げられる。 Among the compounds represented by formula (I), preferred substituents and the like are
As A

Wherein R ⁵ represents a hydrogen atom or a C ₁ -C ₆ alkyl group, Y may be the same or different, and represents one substituent selected from a halogen atom or a halo C ₁ -C ₆ alkyl group Particularly preferred Y is a 3-chloro group or a 3-trifluoromethyl group.)
R ¹ is a hydrogen atom, R ² is a hydrogen atom, a C ₁ -C ₆ alkyl group, a C ₁ -C ₆ alkoxy group, or the like, and R ² together with Y represents a methylene group. It is also preferable to form an indane ring. R ³ is preferably a hydrogen atom, a C ₁ -C ₆ alkoxy group or the like. Further, it is preferred that R ³ together with R ⁵ forms a hetero 6-membered ring containing at least two nitrogen atoms, and the hetero 6-membered ring contains one oxygen atom. The case where a 3,4-oxadiazine ring is formed is preferred. R ⁴ may be the same or different and is preferably a substituted phenyl group having one substituent selected from a halogen atom, a nitro group or a cyano group, or a C ₁ -C ₃ alkoxycarbonyl group. Particularly preferred R ⁴ is a 4-cyanophenyl group or a methoxycarbonyl group. X is preferably a halogen atom, a halo C ₁ -C ₆ alkyl group, a halo C ₁ -C ₆ alkoxy group, or a halo C ₁ -C ₆ alkylthio group. W is preferably an oxygen atom.
As a particularly preferred compound, 4- {2-({[4- (trifluoromethoxy) anilino] carbonylhydrazono) -2- [3- (trifluoromethyl) phenyl] ethylbenzonitrile (2-E, 2-Zmixture) (CAS name) (CAS registration) No. 139968-49-3) Metaflumizone (ISO name, development code BAS-320I or NNI-0250, hereinafter referred to as “Compound A”), methyl (S) -N- [7-chloro-2,3,4a, 5 -tetrahydro-4a- (methoxycarbonyl) indeno [1,2-e] [1,3,4] oxadiazin-2-ylcarbonyl] -4 '-(trifluoromethoxy) carbanilate (IUPAC name).

  The active ingredient compound hydrazinecarboxamide compound used in the present invention is a known compound described in JP-A-5-4958 and the like, and can be produced according to the description in the publication. These hydrazine carboxamide compounds are a novel strain of insecticidal compounds and are also effective against pests that are resistant to existing agents. Mammalian acute toxicity is normal and fish toxicity is low. It can be said that the compound has performance for solving the problems of the prior art.

  A sodium ion channel blocker refers to a compound that prevents the transport of sodium ions across the cell membrane of a neuronal cell.

The amount of the active ingredient used is about 1 to 3000 g / ha as the amount of active ingredient to be applied, although it depends on the type of the target pest.
The content of the hydrazine carboxamide compound as an active ingredient in the agricultural and horticultural poison bait of the present invention can be appropriately determined in consideration of the insecticidal activity of the insecticidal active ingredient to be used and the target pests. The lower limit usually needs to be more than 0.01% by weight, preferably about 0.1% by weight or more. The upper limit amount is not particularly limited, but varies depending on economic efficiency, required residual effect, physical properties of the preparation, etc., and is preferably about 10% by weight, more preferably about 5% by weight or less.

As an attractive / edible carrier, rice bran can be mentioned as a typical example, but is not limited thereto. For example, cereal flour such as starches, wheat flour, corn flour, rice flour, bread crumbs, potatoes, food industry waste such as bran, sake lees, beer lees, okara, fish lees, oil lees, culture media after cultivating moss, pupa Flour, krill, animal powder such as beef and pork flour, sugar such as sugar, glucose, honey, molasses, syrup, etc., plant oil such as soybean oil, rapeseed oil, sesame oil, wheat germ oil, yeast, etc. It can be used in the form of a mixture. Of these, rice bran and sake lees are particularly preferred.
As other components constituting the agricultural and horticultural poison bait, an inert carrier can be appropriately mixed. The inert carrier to be added may be either solid or liquid as long as there is no pest repellent property. Examples of the material that can be a solid carrier include synthetic polymers such as pulverized synthetic resin, clays (for example, kaolin) , Bentonite, acid clay, etc.), talc {eg, talc, pyrophyllite, etc.), silica (eg, diatomaceous earth, silica sand, mica, white carbon (hydrous finely divided silicon, hydrous silicic acid) Some include calcium as a main component.)), Activated carbon, natural minerals (eg, pumice, calcined diatomaceous earth, attapulgite, zeolite, etc.), calcined diatomaceous earth, brick ground, fly ash, sand, plastic carrier, etc. , Polyethylene, polypropylene, etc.), inorganic mineral powders such as calcium carbonate and calcium phosphate, ammonium sulfate, phosphorus , Ammonium nitrate, urea, fertilizer salts depreciation etc., can be exemplified compost or the like, which are used alone or in the form of a mixture of two or more.

Moreover, you may add antioxidant, a preservative, an accidental food inhibitor, the fragrance | flavor for reinforcing the incentive property with respect to a pest, etc. as needed. Here, examples of the antioxidant include erythorbic acid, sodium erythorbate, dibutylhydroxytoluene, dl-α-tocopherol, nordihydroguaiaretic acid, methylhydroxyanisole, propyl gallate, guaiac fat, L-cystine hydrochloride Examples of preservatives include benzoic acid, sodium benzoate, salicylic acid, diphenyl, sorbic acid, potassium sorbate, dehydroacetic acid, sodium dehydroacetate, ethyl parahydroxybenzoate, butyl paraoxybenzoate, and paraoxybenzoic acid. Propyl, calcium propionate, sodium propionate, 5-chloro-2-methyl-4-isothiazolin-3-one, 1,2-benzisothiazolin-3-one, 2-n-octyl-4-isothiazolin-3-one etc It can be mentioned. Examples of the anti-fouling agent include, for example, pepper powder, amaranth, amaranth aluminum lake, erythrosin, erythrosin aluminum lake, new coxin, phloxine, rose bengal, acid red, tartrazine, tartrazine aluminum lake, sunset yellow FCF aluminum lake, Fast green FCF, fast green FCF aluminum lake, brilliant blue FCF, brilliant blue FCF aluminum lake, indigo carmine, indigo carmine aluminum lake, β-carotene, copper chlorophyll and the like. Examples of the flavor include cheese flavor, butter flavor, peanut flavor, peach flavor, strawberry flavor, and milk flavor.
It can be coated with a film-forming substance for the purpose of drug decomposition after application, prevention of spoilage, and controlled release of active ingredients. As the film-forming substance, any substance can be used as long as it can form a film and control the entry and exit of moisture. For example, various resins, polymer compounds, and the like can be used.

  The poison bait of the present invention is an organophosphorus insecticidal compound, carbamate insecticidal compound, pyrethroid insecticidal compound, neonicotinoid insecticidal compound, insect juvenile hormone-like compound, insect as an active ingredient other than hydrazine carboxamide compound A chitin formation inhibitor compound, a natural product having insecticidal activity, or the like can also be added and used. In addition, synergists (activity enhancers) such as metabolic inhibitors can be added.

  Specific examples of the organic phosphorus-based insecticidal compound that can be used include, for example, chlorpyrifos, chlorpyrifosmethyl, diazinon, fenitrothion, fenthion, malathion, pyrimifosmethyl, prothiophos, pyridafenthion, isoxathione, trichlorfone, etc., specific examples of carbamate-based insecticidal compounds As, for example, BPMC, ethiophen curve, MPMC, propoxer, NAC (carbaryl), XMC, etc. Specific examples of pyrethroid insecticidal compounds include, for example, cypermethrin, deltamethrin, fenpropraslin, fenvalerate, permethrin, Cyfluthrin, traromeslin, fluthyrine, biphenothrin, cyhalothrin, cycloprotorin, fulvalinate, etofenprox, silaneoff Emissions, tefluthrin, etc. Specific examples of the neonicotinoid insecticidal compounds, for example, imidacloprid, nitenpyram, acetamiprid, thiamethoxam, clothianidin, thiacloprid, dinotefuran and the like, respectively. Specific examples of insect juvenile hormone-like compounds include, for example, metoprene, pyriproxyfen, phenoxy curve, etc. Specific examples of insect chitin formation inhibitors include, for example, diflubenzuron, teflubenzuron, chlorfluazuron, flufenoxuron Specific examples of insecticidal compounds of other strains such as hexaflumuron, novallon, cyromazine, buprofezin, etc. include, for example, fipronil, chlorfenapyr, emamectin benzoate, abamectin, tebufenozide, methoxyphenozide, chromafenozide, spinosin, pyridalyl, flucripyrim, SI-0009 (Development code), DKI-0001 (development code), hydramethylnon, metaldehyde and the like can be mentioned, but are not limited thereto.

  The poison bait of the present invention can further contain an insect parasitic fungus as an active ingredient other than the hydrazine carboxamide compound. For example, Metarhizium metarhizium anisopriae and Beauveria bowberia bassiana (Beauveria bassiana).

The agricultural and horticultural poison bait according to the present invention is prepared by adding an edible carrier or the like to a suitable solvent such as water and kneading it into a suitable dosage form such as a granule or a tablet. Then, the hydrazine carboxamide compound as an active ingredient It can be manufactured by impregnating a solution containing, and then drying again. Further, it can be produced by adding a hydrazine carboxamide compound to the edible carrier from the beginning and molding it into an appropriate dosage form such as a granule or a tablet by a conventional method.
In addition, the application of the arthropod poison bait of the present invention is not particularly limited as long as it is applied to a place where the target arthropod is active. Various methods can be used in accordance with conventional methods. For example, spraying to the whole cultivation place, soil surface spraying, soil mixing, spraying to seedling carriers, application to around the seedling container, application to furrows, application to ridges, and molded poison bait It can also be used in By using a floating preparation with a water-repellent surface, it can be applied to paddy fields and attached to a plant body.

The poison bait of the present invention exhibits an excellent control effect against various pests, and acts effectively on the following pests, but can also be used on other pests, and all that act on the soil surface or near the surface layer. Can also be used against other pests. Examples of pests include the following pests.
Lepidoptera, for example, Agrotis segetum, Agrotis ipsilon, Agrotis tokionis, Agrotis exexclamationis, Xestia c-nigrum, Diarsia canescens, Diarsia canescens, Spodoptera litura, Mamestra brassicae, Spodoptera exigua, Helicoverpa armigera, Heliothis spp., Heliothis spp. ), Shipediatoga (Parapediasia teterrella), Spodoptera depravata,

Diptera, e.g., Homorocoryphus lineosus, Stenchaetothrips biformis, Calyptotrypes hibinonis, Teleogryllus emma, Glylotalpa orientaliszo, Loca Acrida cinerea, etc.

Coleoptera, for example, Anomala spp., Maladera spp., Blitopertha orientalis, Heptophylla picea, Phyllopertha diversa, Pilla japonica, P Agriotes ogurae, Melanotus okinawenisis, Diabrotica spp., Sphenophorus venatus, Scepticus spp. Eyes, for example, Ophiomyia lappivora, Bradisia agrestis, onion flies, Delia floralis, Hylemya platura, Dicranoptychap. Slugs and snails belonging to steel animals, shell steel Oka pill bugs, such as belonging to the object. Especially, it has an excellent control effect against lepidopterous pests. The bark beetle is a general term for larvae of lepidopterous pests among the pests and the like shown in the above specific examples. Among them, old larvae of moths and mushrooms are generally difficult to control, and the excellent effects of this agent are characteristically exhibited.

Examples are shown below specifically, but the present invention is not limited to the following examples.
Production Example 1
Mixing 75% by weight of rice bran and 25% by weight of distilled water, granulating with an extrusion granulator (particle size 2.5mm), drying (50 ° C, 6 hours), grinding (grain length: 3-8mm) After that, a carrier was obtained. The carrier was impregnated with 0.1% by weight of Compound A (diluted in 2000 ppm of Compound A per 1 g of carrier (as a preservative, 5-chloro-2-methyl-4-isothiazolin-3-one (trade name: Caisson ) Was added at 0.05%) and impregnated at a rate of 0.5 ml). Then, after passing through a drying process (50 ° C., 6 hours) again, the poison bait of the present invention was obtained. The following tests were conducted using the poison bait obtained in this production example. In the following examples, a poison bait indicates a substance containing an active ingredient at a certain ratio. The poison bait produced as described above has, for example, 1 g of active ingredient in 1 kg of poison bait.

Test Example 1 Superiority of poison bait in compound A over conventional dosage form (spraying agent) The field in the greenhouse is surrounded by a plastic plate with a height of 30 cm every 1 m ² (1 x 1 m), and cabbage After transplanting 25 seedlings, the poison bait 3 or 6 kg / 10 are produced in Production Example 1 was uniformly dispersed on the soil surface (the control spray was treated with 200 liters / 10 are by hand spray), then 6 20 old larvae were released. After 14 days of insect release, the stock removal rate of cabbage seedlings was investigated, and the control rate was calculated. This test was done in duplicate. The results are shown in Table 1. In the table of each test example below, “ai” represents an active ingredient, “a” in 10a represents R, and “SC” represents an aqueous suspension.
The control rate was calculated according to the following formula.
Control rate = 100− (the rate of stock removal in the treated area / the rate of stock missing in the untreated area) × 100

Test example 2 Comparison of sustained effects with organophosphorus insecticides, carbamate insecticides, and pyrethroid insecticides The field in the greenhouse is surrounded by a plastic plate with a height of 30 cm every 1 m ² (1 x 1 m). Then, 25 cabbage seedlings were transplanted therein, and 3 kg / 10 ares of the poison bait prepared in Production Example 1 were evenly spread on the soil surface immediately and after 30 days, 30 6th instar larvae were released. After 14 days of insect release, the cabbage seedling loss rate was investigated, and the control rate was calculated in the same manner as in Test Example 1. This test was done in duplicate. The results are shown in Table 2.

Test example 3 Effect on cabbage moth in a large-scale test The field in the greenhouse was surrounded by a plastic plate with a height of 30 cm every 15 m ² (6 x 2.5 m), and 63 cabbage seedlings were transplanted into it. Then, 4 kg / 10 ares of poison bait produced in Example 1 (control NAC poison bait is 6 kg / 10 ares) were uniformly dispersed on the soil surface, and then 35 5-6 instar larvae were released. The absence rate of cabbage seedlings was investigated 7 days, 14 days and 20 days after insect release, and the control rate was calculated in the same manner as in Test Example 1. This test was done in duplicate. The results are shown in Table 3.

Test Example 4 Effects on organophosphorus insecticides, carbamate insecticides, pyrethroid insecticide-resistant strains of Spodoptera litura The field in the greenhouse is surrounded by a plastic plate with a height of 30 cm every 1 m ² (1 × 1 m). 25 seedlings of cabbage were transplanted into it, 3 kg / 10 are of poison bait produced in Example 1 was uniformly dispersed on the soil surface, and 80 5-6 instar larvae of multi-drug-resistant Spodoptera were released. did. After 14 days of insect release, the cabbage seedling loss rate was investigated, and the control rate was calculated in the same manner as in Test Example 1. This test was done in duplicate. The results are shown in Table 4.

Test Example 5 Effects on organophosphorus insecticides, carbamate insecticides, pyrethroid insecticide resistant strains, Tobacco moths The field in the greenhouse is surrounded by a plastic plate with a height of 30 cm every 1 m ² (1 × 1 m). Twenty-five cabbage seedlings were transplanted therein, and 4 kg / 10 ares of poison bait produced in Example 1 were uniformly dispersed on the soil surface, and then 20 5th instar larvae of multi-drug resistant giant tobacco were released. Nine days after the release, the number of live insects in the ward was examined, and the control rate was calculated. This test was done in duplicate. The results are shown in Table 5.
The control rate was calculated according to the following formula.
Control rate = 100− (number of surviving insects in treated group / number of surviving insects in untreated group) × 100

Test Example 6 Effects on adult mackerel crickets Fields in a greenhouse were covered with tunnel cultivation using nylon mesh every 0.8 m ² (40 × 100 cm), and 20 Chinese cabbage seedlings were transplanted therein, Example 1 After poisoning the poison bait 6kg / 10 are manufactured uniformly in the soil surface, 14 adult enmacrickets were released. The number of live insects and the number of missing strains in the ward were examined 4 days and 9 days after release (only after 9 days), and the control rate was calculated in the same manner as in Test Example 5. This test was done in duplicate. The results are shown in Table 6.

  As shown in Table 1, the poison bait of the present invention has an excellent effect at a dose of 1/16 or less of the hydrazine carboxamide compound in a condition where a sufficient effect is not recognized even when sprayed. It is a technology that can be used to significantly reduce the dosage of hydrazine carboxamide compounds. Further, as shown in Table 3, the effect sustainability is clearly superior to conventional agricultural and horticultural poison baits. As shown in Tables 4 and 5, the conventional agricultural and horticultural poison baits exhibit excellent effects also on various pests exhibiting resistance. Furthermore, in terms of safety, it is useful as a poisonous bait for agriculture and horticulture that is superior to conventional products.

  The poisonous bait of the present invention is used for the prevention and control of various pests on agricultural land for agricultural and horticultural purposes. In addition, since it has low toxicity to mammals, it can also be used for prevention and control of pests in food storage.

Claims (10)

An agricultural and horticultural poisonous bait comprising an edible carrier attracting pests and a sodium channel blocker as an active ingredient. Sodium channel blockers are represented by the general formula (I):

[Where A is

(Wherein R ⁵ represents a hydrogen atom or a C ₁ -C ₆ alkyl group, Y may be the same or different, and _one or two substituents selected from a halogen atom and a halo C ₁ -C ₆ alkyl group) Group) or

Wherein R ⁵ and Y are the same as above, and R ⁶ is selected from a hydrogen atom, a C ₁ -C ₆ alkylcarbonyl group, a phenylcarbonyl group, or a C ₁ -C ₆ alkyl group which may be the same or different. Represents a substituted phenylcarbonyl group having 1 to 2 substituents.).
R ¹ represents a hydrogen atom, a C ₁ -C ₆ alkyl group or a C ₁ -C ₃ alkoxycarbonyl group. R ² represents a hydrogen atom, a hydroxyl group, a C ₁ -C ₆ alkyl group, a C ₁ -C ₆ alkoxy group, a C ₁ -C ₆ alkylcarbonyl group or a phenylcarbonyl group, and R ² together with Y It represents a methylene group and can form an indane ring. R ³ represents a hydrogen atom, a hydroxyl group, a C ₁ -C ₆ alkyl group, a C ₁ -C ₆ alkoxy group, a C ₁ -C ₆ alkylcarbonyl group or a phenylcarbonyl group, and R ³ together with R ⁵ A hetero 5-membered ring or a hetero 6-membered ring containing at least two nitrogen atoms, and the hetero 6-membered ring can contain one oxygen atom. R ⁴ may be the same as or different from a hydrogen atom, and represents a substituted phenyl group having 1 to 2 substituents selected from a halogen atom, a nitro group and a cyano group, or a C ₁ -C ₃ alkoxycarbonyl group. X is a halogen atom, cyano group, halo C ₁ -C ₆ alkyl group, halo C ₁ -C ₆ alkoxy group, halo C ₁ -C ₆ alkylthio group, halo C ₁ -C ₆ alkylsulfinyl group or halo C ₁ -C _{6 represents} an alkylsulfonyl group. W represents an oxygen atom or a sulfur atom. ]
The poisonous bait for agricultural and horticultural use according to claim 1, which is a hydrazine carboxamide compound represented by the formula: The agricultural and horticultural poison bait according to claim 1, wherein the sodium channel blocker is metaflumizone. The poisonous bait for agricultural and horticultural use according to any one of claims 1 to 3, wherein the content of the sodium channel blocker is 0.01 to 10% by weight. The poisonous bait for agricultural and horticultural use according to any one of claims 1 to 4, comprising rice bran as an edible carrier. The poisonous bait for agricultural and horticultural use according to any one of claims 1 to 4, characterized by containing sake lees as an edible carrier. A method for using an agricultural and horticultural poison bait characterized by applying an effective amount of the agricultural and horticultural poison bait according to any one of claims 1 to 6 to soil around a crop. A method for controlling agricultural and horticultural pests, comprising applying an effective amount of the agricultural and horticultural poison bait according to any one of claims 1 to 6 to soil around a crop. The method for controlling agricultural and horticultural pests according to claim 8, wherein the agricultural and horticultural pests are Nechirimes. The method for controlling agricultural and horticultural pests according to claim 8 or 9, wherein the agricultural and horticultural pests are bark beetles that are resistant to one or more drugs selected from organophosphorus insecticides, carbamate insecticides, or pyrethroid insecticides. .