JP2006129884A - Mixed injection member, connection member and medical implement - Google Patents

Mixed injection member, connection member and medical implement Download PDF

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Publication number
JP2006129884A
JP2006129884A JP2004318650A JP2004318650A JP2006129884A JP 2006129884 A JP2006129884 A JP 2006129884A JP 2004318650 A JP2004318650 A JP 2004318650A JP 2004318650 A JP2004318650 A JP 2004318650A JP 2006129884 A JP2006129884 A JP 2006129884A
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housing
blood
side tube
mixed injection
dead space
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Hironobu Ishida
裕伸 石田
Kuniharu Hamazaki
邦春 浜崎
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SB Kawasumi Laboratories Inc
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Kawasumi Laboratories Inc
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a mixed injection member and a medical implement, capable of preventing stagnation of blood by a swelling part without stagnating blood in a dead space. <P>SOLUTION: The mixed injection member 1 has a plug body 4 attached to a port 3 in the upper part of a housing 4, and a blood inflow side tube T and a blood outflow side tube T connected to both sides of the housing 4. The mixed injection member 1 also has the swelling part 6 formed on the bottom of the housing 4 to detour the blood flowing into the housing in the direction toward the dead space S in the upper part of the housing 4. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

本発明は、薬液等を注入する混注部材、接続部材の改良に関するもので、血液の滞留や凝固のない混注部材、接続部材に関する。本発明の混注部材は、血液回路、輸血・輸液セット等の医療用具に使用される。本発明の接続部材は、生理食塩液、薬液等の注入ライン等のジョイント（接続管、Ｔ字管ともいう）等の医療用具に使用される。   The present invention relates to an improvement in a mixed injection member and a connection member for injecting a chemical solution and the like, and relates to a mixed injection member and a connection member free from blood retention and coagulation. The mixed injection member of the present invention is used in medical devices such as blood circuits and blood transfusion / infusion sets. The connection member of the present invention is used for medical devices such as joints (also referred to as connection pipes or T-shaped pipes) such as injection lines for physiological saline and chemicals.

図５、６の混注部材５１（現在使用されている混注部材５１の断面図）に例示するように、ハウジング５２の上部と、栓体５４の下部にデッドスペースＳが存在するため、ハウジング５２内に流入してきた血液はデッドスペースＳ付近で滞留しやすく、血液の凝固を惹起することがあった。
また図７、８の接続部材６１（現在使用されている接続部材６１の断面図）に例示するように、ポート６３内部にデッドスペースＳが存在するため、ハウジング６２内に流入してきた血液はデッドスペースＳ付近で滞留しやすく、血液の凝固を惹起することがあった。 As illustrated in the mixed injection member 51 of FIGS. 5 and 6 (a cross-sectional view of the currently used mixed injection member 51), since there is a dead space S in the upper part of the housing 52 and the lower part of the plug body 54, The blood that has flowed into the water tends to stay in the vicinity of the dead space S and may cause blood coagulation.
Further, as illustrated in the connection member 61 of FIGS. 7 and 8 (a cross-sectional view of the connection member 61 currently used), since the dead space S exists in the port 63, the blood flowing into the housing 62 is dead. It tends to stay in the vicinity of the space S and may cause blood coagulation.

なお特許文献１に例示されているように、医療用活栓の発明において、ハウジング内壁面に、三箇所の縦溝を形成し、薬液（一般に血液より粘性低い）の流れる方向を調整して、滞留をなくする旨が開示されているが、これらの複数の溝では、粘性の高い血液が通過する際には、滞留、凝固の原因となるので好ましくない。
特開２００３−１５９３３６号公報（図２、図３、［００１６］［００１８］［００２０］［００２２］） As exemplified in Patent Document 1, in the invention of a medical stopcock, three longitudinal grooves are formed on the inner wall surface of the housing, and the flow direction of the drug solution (generally less viscous than blood) is adjusted to stay. However, it is not preferable that the plurality of grooves cause retention and coagulation when blood with high viscosity passes.
JP 2003-159336 A (FIG. 2, FIG. 3, [0016] [0018] [0020] [0022])

本発明が解決しようとする問題点は、ハウジング内に流入してきた血液はデッドスペースＳ付近で滞留しやすく、血液の凝固を惹起する点である。   The problem to be solved by the present invention is that blood flowing into the housing tends to stay in the vicinity of the dead space S and causes blood coagulation.

そこで本発明者は以上の課題を解決するために、鋭意検討を重ねた結果次の発明に到達した。
［１］本発明は、ハウジング（４）上部のポート（３）に栓体（４）を装着し、当該ハウジング（４）の両側に血液流入側チューブ（Ｔ）と血液流出側チューブ（Ｔ）を接続した混注部材（１）において、
前記ハウジング（４）の底部に、ハウジング（４）内に流入してきた血液を当該ハウジング（４）上部のデッドスペース（Ｓ）方向に迂回させることのできる隆起部（６）を形成した混注部材（１）を提供する。
［２］本発明は、前記隆起部（６）は、血液流入側チューブ（Ｔ）からハウジング（４）内に流入してきた血液が、衝突した時に、ハウジング４上部のデッドスペース（Ｓ）方向に流れを変え、さらに上部から下降して、血液流出側チューブ（Ｔ）から排出できるようにした形状である［１］に記載の混注部材（１）を提供する。
［３］本発明は、ハウジング（１４）上部のポート（１３）に液体移送チューブ（Ｔ）を接続した接続部材（１１）において、当該ハウジング（４）の両側に血液流入側チューブ（Ｔ）と血液流出側チューブ（Ｔ）を接続した接続部材（１１）において、
前記ハウジング（１４）の底部に、ハウジング（１４）内に流入してきた血液を当該ハウジング（１４）上部のデッドスペース（Ｓ）方向に迂回させることのできる隆起部（１６）を形成した接続部材（１１）を提供する。
［４］本発明は、隆起部（１６）は、血液流入側チューブ（Ｔ）からハウジング（１４）内に流入してきた血液が、衝突した時に、ポート（１３）内のデッドスペース（Ｓ）方向に流れを変え、さらにポート（１３）から下降して、血液流出側チューブ（Ｔ）から排出できるようにした形状である［３］に記載の接続部材（１１）を提供する。
［５］本発明は、［１］ないし［４］に記載の混注部材及び／又は接続部材（１１）を含む医療用具を提供する。 Therefore, as a result of intensive studies to solve the above problems, the present inventor has reached the following invention.
[1] In the present invention, the plug (4) is mounted on the port (3) at the top of the housing (4), and the blood inflow side tube (T) and the blood outflow side tube (T) are provided on both sides of the housing (4). In the mixed injection member (1) connected with
A co-infusion member (in the bottom of the housing (4)) is formed with a raised portion (6) capable of diverting blood flowing into the housing (4) in the direction of the dead space (S) above the housing (4). 1) is provided.
[2] In the present invention, the protruding portion (6) is arranged in the direction of the dead space (S) above the housing 4 when the blood flowing into the housing (4) from the blood inflow side tube (T) collides. The co-infusion member (1) according to [1], which has a shape that changes the flow and further descends from the upper part so as to be discharged from the blood outflow side tube (T).
[3] In the connecting member (11) in which the liquid transfer tube (T) is connected to the port (13) at the upper part of the housing (14), the present invention provides a blood inflow side tube (T) on both sides of the housing (4). In the connecting member (11) connected to the blood outflow side tube (T),
A connecting member (formed with a raised portion (16) at the bottom of the housing (14) capable of diverting blood flowing into the housing (14) in the direction of the dead space (S) above the housing (14) ( 11).
[4] According to the present invention, the protruding portion (16) is formed in the direction of the dead space (S) in the port (13) when the blood flowing into the housing (14) from the blood inflow side tube (T) collides. The connection member (11) according to [3] is provided, which has a shape in which the flow is changed to, and the flow is further lowered from the port (13) to be discharged from the blood outflow side tube (T).
[5] The present invention provides a medical device including the co-infusion member and / or connecting member (11) according to [1] to [4].

本発明の混注部材１は、ハウジング４内に流入してきた血液は、隆起部６に衝突して、ハウジング４上部のデッドスペースＳ方向に流れ、さらに上部から下降して、排出されるので、デッドスペースＳに滞留することはない。接続部材１１においても同様に、隆起部１６により血液の滞留を防ぐことができる。   In the mixed injection member 1 of the present invention, blood that has flowed into the housing 4 collides with the raised portion 6, flows in the direction of the dead space S at the top of the housing 4, further descends from the top, and is discharged. It does not stay in the space S. Similarly, in the connection member 11, the stagnation of blood can be prevented by the raised portions 16.

図１は本発明の混注部材１の概略図（一部切欠断面図）、図２は図１の使用状態図である。
［混注部材１］
本発明の混注部材１は、ハウジング４上部のポート３に栓体４を装着し、当該ハウジング４の両側に血液流入側チューブＴと血液流出側チューブＴを接続した混注部材１において、前記ハウジング４の底部に、ハウジング４内に流入してきた血液を当該ハウジング４上部のデッドスペースＳ方向に迂回させることのできる隆起部６を形成した混注部材１である。 FIG. 1 is a schematic view (partially cutaway cross-sectional view) of a co-infusion member 1 of the present invention, and FIG. 2 is a use state diagram of FIG.
[Mixed injection member 1]
The mixed injection member 1 of the present invention is the mixed injection member 1 in which the plug 4 is attached to the port 3 at the top of the housing 4 and the blood inflow side tube T and the blood outflow side tube T are connected to both sides of the housing 4. The co-infusion member 1 is formed with a raised portion 6 that can divert blood that has flowed into the housing 4 in the direction of the dead space S above the housing 4.

［隆起部６］
隆起部６は、図１、図２の例示では、ハウジング４の底部から略三角形状（断面が略三角形状で、チューブＴの径ないしハウジング４の径（幅）よりも若干狭い幅を有する）に立設されている。
図１、図２の例示では血液流入側チューブＴからハウジング４内に流入してきた血液は、隆起部６の前方斜面に衝突し、ハウジング４上部のデッドスペースＳ方向に流れ、当該デッドスペースＳから、隆起部６の後方斜面に沿って、血液流出側チューブＴから排出される。デッドスペースＳを必ず血液が通過するので、デッドスペースＳに血液が滞留することなく、血液の凝固も発生しない。
隆起部６の形態は、血液流入側チューブＴからハウジング４内に流入してきた血液が、衝突した時に、ハウジング４上部のデッドスペースＳ方向に流れを変え、さらに上部のデッドスペースＳから下降して、血液流出側チューブＴから排出できるようにした形状であれば何でも良い。
例えば、球冠状、角柱状、角錐台状、円錐台状等何でも良い。 [Bump 6]
In the illustration of FIGS. 1 and 2, the raised portion 6 is substantially triangular from the bottom of the housing 4 (the cross section is substantially triangular, and has a width slightly narrower than the diameter of the tube T or the diameter (width) of the housing 4). Is erected.
In the illustration of FIG. 1 and FIG. 2, the blood that has flowed into the housing 4 from the blood inflow side tube T collides with the front slope of the raised portion 6 and flows in the direction of the dead space S above the housing 4. The blood is discharged from the blood outflow side tube T along the rear slope of the raised portion 6. Since blood always passes through the dead space S, blood does not stay in the dead space S, and blood coagulation does not occur.
The form of the raised portion 6 is that when blood that has flowed into the housing 4 from the blood inflow side tube T collides, the flow changes in the direction of the dead space S above the housing 4 and further descends from the upper dead space S. Any shape can be used as long as it can be discharged from the blood outflow side tube T.
For example, any shape such as a spherical crown shape, a prism shape, a truncated pyramid shape, or a truncated cone shape may be used.

またポート３に装填される栓体５は、アダプター（図示せず）のルアー部（注入口ともい）を挿入可能なスリットＳＬ付きの栓体４であれば何でも良い。スリットの形態もルアー部（注入口）を挿入可能な形態（例えば縦断面の途中から形成されているものあるいは縦断面の上端から下端に亘って形成されたもの等）であれば何でも良い。また栓体４に鋭利な針部材を刺通する場合はスリットＳＬは不要である。
また図１の例示では、栓体４はポート３の内部に配置されているが、ポート３の下部に配置（厳密にいえば、ポート３下部とハウジング２の上段部との間）しても良い。
ポート３とキャップ５は係合部（具体的には、突起と溝で、相互に入れ替わっても良い）により係合される。 The plug body 5 loaded in the port 3 may be anything as long as it is a plug body 4 with a slit SL into which a luer part (also referred to as an inlet) of an adapter (not shown) can be inserted. The shape of the slit may be anything as long as the luer part (injection port) can be inserted (for example, formed from the middle of the longitudinal section or formed from the upper end to the lower end of the longitudinal section). Further, when a sharp needle member is pierced through the plug body 4, the slit SL is not necessary.
In the example of FIG. 1, the plug body 4 is disposed inside the port 3, but may be disposed at the lower portion of the port 3 (strictly speaking, between the lower portion of the port 3 and the upper stage portion of the housing 2). good.
The port 3 and the cap 5 are engaged with each other by an engaging portion (specifically, a protrusion and a groove may be interchanged).

図３は本発明の接続部材１１の概略図（一部切欠断面図）、図４は図３の使用状態図である。
［接続部材１１］
本発明の接続部材１１は、ハウジング１４上部のポート１３に、液体（薬液、輸液、生理食塩液等）の移送チューブＴを接続し、当該ハウジング４の両側に血液流入側チューブＴと血液流出側チューブＴを接続した接続部材１１において、ハウジング１４の底部に、ハウジング１４内に流入してきた血液を当該ポート１３内のデッドスペースＳ方向に迂回させることのできる隆起部１６を形成した接続部材１１である。
［隆起部１６］
隆起部１６の形態は、前記隆起部６と実質的に同じであるから詳細な説明は省略する。
図３、図４の例示では血液流入側チューブＴからハウジング１４内に流入してきた血液は、隆起部１６の前方斜面に衝突し、ポート１３内のデッドスペースＳ方向に流れ、当該デッドスペースＳから、隆起部１６の後方斜面に沿って、血液流出側チューブＴから排出される。デッドスペースＳを必ず血液が通過するので、デッドスペースＳに血液が滞留することなく、血液の凝固も発生しない。 FIG. 3 is a schematic view (partially cutaway sectional view) of the connecting member 11 of the present invention, and FIG. 4 is a use state diagram of FIG.
[Connecting member 11]
In the connecting member 11 of the present invention, a transfer tube T for liquid (medical solution, infusion, physiological saline, etc.) is connected to a port 13 above the housing 14, and a blood inflow side tube T and a blood outflow side are provided on both sides of the housing 4. In the connecting member 11 to which the tube T is connected, the connecting member 11 is formed with a raised portion 16 at the bottom of the housing 14 that can divert blood flowing into the housing 14 in the direction of the dead space S in the port 13. is there.
[Bump 16]
Since the shape of the raised portion 16 is substantially the same as that of the raised portion 6, a detailed description thereof will be omitted.
3 and 4, the blood that has flowed into the housing 14 from the blood inflow side tube T collides with the front slope of the raised portion 16, flows in the direction of the dead space S in the port 13, and from the dead space S The blood is discharged from the blood outflow side tube T along the rear slope of the raised portion 16. Since blood always passes through the dead space S, blood does not stay in the dead space S, and blood coagulation does not occur.

本発明の混注部材１の概略図（一部切欠断面図）Schematic of the mixed injection member 1 of the present invention (partially cutaway sectional view) 図１の使用状態図Usage state diagram of FIG. 本発明の接続部材１１の概略図（一部切欠断面図）Schematic of the connecting member 11 of the present invention (partially cutaway sectional view) 図３の使用状態図Usage state diagram of FIG. 従来の混注部材の概略図（一部切欠断面図）Schematic diagram of a conventional mixed injection member (partially cutaway sectional view) 図５の使用状態図Usage state diagram of FIG. 従来の接続部材の概略図（一部切欠断面図）Schematic diagram of a conventional connection member (partially cutaway sectional view) 図７の使用状態図Usage state diagram of FIG.

符号の説明Explanation of symbols

１ 混注部材
２ ハウジング
３ ポート
４ 栓体
５ キャップ
６ 隆起部
Ｔ チューブ
Ｓ デッドスペース
ＳＬ スリット
１１ 接続部材
１２ ハウジング
１３ ポート
１６ 隆起部
Ｃ かんし（クランプ） DESCRIPTION OF SYMBOLS 1 Mixed injection member 2 Housing 3 Port 4 Plug body 5 Cap 6 Raised part T Tube S Dead space SL Slit 11 Connection member 12 Housing 13 Port 16 Raised part C Hair clamp (clamp)

Claims (5)

ハウジング（４）上部のポート（３）に栓体（４）を装着し、当該ハウジング（４）の両側に血液流入側チューブ（Ｔ）と血液流出側チューブ（Ｔ）を接続した混注部材（１）において、
前記ハウジング（４）の底部に、ハウジング（４）内に流入してきた血液を当該ハウジング（４）上部のデッドスペース（Ｓ）方向に迂回させることのできる隆起部（６）を形成したことを特徴とする混注部材（１）。 A mixed injection member (1) in which a plug (4) is attached to a port (3) at the top of the housing (4), and a blood inflow side tube (T) and a blood outflow side tube (T) are connected to both sides of the housing (4). )
A raised portion (6) capable of diverting blood flowing into the housing (4) in the direction of the dead space (S) above the housing (4) is formed at the bottom of the housing (4). The mixed injection member (1). 前記隆起部（６）は、血液流入側チューブ（Ｔ）からハウジング（４）内に流入してきた血液が、衝突した時に、ハウジング４上部のデッドスペース（Ｓ）方向に流れを変え、さらに上部から下降して、血液流出側チューブ（Ｔ）から排出できるようにした形状であることを特徴とする請求項１に記載の混注部材（１）。   When the blood flowing into the housing (4) from the blood inflow side tube (T) collides with the raised portion (6), the flow changes in the direction of the dead space (S) above the housing 4, and further from the upper part. The co-infusion member (1) according to claim 1, wherein the co-infusion member (1) has a shape that can be lowered and discharged from the blood outflow side tube (T). ハウジング（１４）上部のポート（１３）に液体移送チューブ（Ｔ）を接続した接続部材（１１）において、当該ハウジング（４）の両側に血液流入側チューブ（Ｔ）と血液流出側チューブ（Ｔ）を接続した接続部材（１１）において、
前記ハウジング（１４）の底部に、ハウジング（１４）内に流入してきた血液を当該ハウジング（１４）上部のデッドスペース（Ｓ）方向に迂回させることのできる隆起部（１６）を形成したことを特徴とする接続部材（１１）。 In the connecting member (11) in which the liquid transfer tube (T) is connected to the port (13) at the top of the housing (14), the blood inflow side tube (T) and the blood outflow side tube (T) are provided on both sides of the housing (4). In the connecting member (11) connected with
A raised portion (16) capable of diverting blood flowing into the housing (14) in the direction of the dead space (S) above the housing (14) is formed at the bottom of the housing (14). Connection member (11). 隆起部（１６）は、血液流入側チューブ（Ｔ）からハウジング（１４）内に流入してきた血液が、衝突した時に、ポート（１３）内のデッドスペース（Ｓ）方向に流れを変え、さらにポート（１３）から下降して、血液流出側チューブ（Ｔ）から排出できるようにした形状であることを特徴とする請求項３に記載の接続部材（１１）。   The raised portion (16) changes the flow in the direction of the dead space (S) in the port (13) when the blood flowing into the housing (14) from the blood inflow side tube (T) collides, The connecting member (11) according to claim 3, wherein the connecting member (11) is shaped so as to be lowered from (13) and discharged from the blood outflow side tube (T). 請求項１ないし請求項４に記載の混注部材及び／又は接続部材（１１）を含むことを特徴とする医療用具。   A medical device comprising the mixed injection member and / or the connection member (11) according to claim 1.
JP2004318650A 2004-11-02 2004-11-02 Mixed injection member, connection member and medical implement Pending JP2006129884A (en)

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Publication number Priority date Publication date Assignee Title
JP2008200312A (en) * 2007-02-21 2008-09-04 Nippon Sherwood Medical Industries Ltd Utensil for mixed injection of liquid
JP2010505551A (en) * 2006-10-05 2010-02-25 ベクトン・ディキンソン・アンド・カンパニー Direction of fluid flow in vascular access device
WO2013047006A1 (en) * 2011-09-27 2013-04-04 テルモ株式会社 Connector
WO2015087982A1 (en) 2013-12-11 2015-06-18 日機装株式会社 Co-injection member
JP2015521933A (en) * 2012-07-09 2015-08-03 インドゥストリー・ボルラ・ソシエタ・ペル・アチオニＩｎｄｕｓｔｒｉｅ Ｂｏｒｌａ Ｓ．ｐ．Ａ． Medical line flow system
IT201600075597A1 (en) * 2016-07-19 2018-01-19 Borla Ind FLOW COMPONENT PARTICULARLY FOR MEDICAL LINES FOR HEMODIALYSIS

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JPH06190350A (en) * 1992-06-16 1994-07-12 Nomura Micro Sci Kk Cleaning acceleration method for retention water section of piping system
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JP2010505551A (en) * 2006-10-05 2010-02-25 ベクトン・ディキンソン・アンド・カンパニー Direction of fluid flow in vascular access device
JP2008200312A (en) * 2007-02-21 2008-09-04 Nippon Sherwood Medical Industries Ltd Utensil for mixed injection of liquid
WO2013047006A1 (en) * 2011-09-27 2013-04-04 テルモ株式会社 Connector
CN103826693A (en) * 2011-09-27 2014-05-28 泰尔茂株式会社 Connector
EP2762194A4 (en) * 2011-09-27 2015-08-26 Terumo Corp Connector
US9089680B2 (en) 2011-09-27 2015-07-28 Terumo Kabushiki Kaisha Connector
JP2015521933A (en) * 2012-07-09 2015-08-03 インドゥストリー・ボルラ・ソシエタ・ペル・アチオニＩｎｄｕｓｔｒｉｅ Ｂｏｒｌａ Ｓ．ｐ．Ａ． Medical line flow system
WO2015087982A1 (en) 2013-12-11 2015-06-18 日機装株式会社 Co-injection member
US10315022B2 (en) 2013-12-11 2019-06-11 Nikkiso Company Limited Co-injection member
IT201600075597A1 (en) * 2016-07-19 2018-01-19 Borla Ind FLOW COMPONENT PARTICULARLY FOR MEDICAL LINES FOR HEMODIALYSIS
EP3272389A1 (en) * 2016-07-19 2018-01-24 Industrie Borla S.p.A. Flow component particularly for haemodialysis medical lines
US10668205B2 (en) 2016-07-19 2020-06-02 Industrie Borla S.P.A. Flow component particularly for haemodialysis medical lines
AU2017204566B2 (en) * 2016-07-19 2021-10-28 Industrie Borla S.P.A Flow component particularly for haemodialysis medical lines

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