JP2006104141A - Gel-like cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a gel preparation having excellent salt tolerance even in the coexistence of a bleaching ingredient, or the like. <P>SOLUTION: This gel-like cosmetic comprises (1) an alkyl-modified carboxyvinyl polymer and/or its salt, (2) a carboxyvinyl polymer and/or its salt, (3) a water-swellable polymer and (4) etidronic acid and/or its salt. An acrylic acid-starch graft polymer and/or its salt is preferable as the water-swellable polymer. The cosmetic is preferably a body cosmetic. The cosmetic preferably contains a bleaching component and/or an antiinflammatory component. The bleaching component is preferably ascorbic acid and/or its derivative, arbutin and/or its salt, ellagic acid and/or its salt, tranexamic acid and/or its salt or 4-methoxysalicylic acid and/or its salt. The antiinflammatory component is stearyl glycyrrhetate, dipotassium glycyrrhizate or tranexamic acid and/or its salt. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a cosmetic, and more particularly to a cosmetic suitable for a gel cosmetic.

  Gel-like cosmetics are widely applied especially to summer cosmetics and the like because of their cleanliness of usability and convenience that can be accurately administered to the application site. Such a gel-like cosmetic is usually formulated by utilizing the gelling action of a carboxyvinyl polymer salt. The gel structure made by such a salt of carboxyvinyl polymer is usually very stable, but in the form where salt exists on the skin, the salt resistance is poor, so the structure is drastically set. There is a fault that collapses. Various attempts have been made to improve this point, but there is currently no definitive one. As such an attempt, for example, a method in which the gel structure is replaced with an alkyl-modified carboxyvinyl polymer and / or a salt thereof without using a carboxyvinyl polymer or a salt thereof (see, for example, Patent Document 1 and Patent Document 2). ), A method depending on the gel structure formed by combining an alkyl-modified carboxyvinyl polymer and / or a salt thereof and a carboxyvinyl polymer and / or a salt thereof (see, for example, Patent Document 3), And a technique of combining sodium acrylate / starch graft polymer (see, for example, Patent Document 4). However, even with such a technique, there was a limit to the improvement of salt tolerance. This tendency was particularly remarkable when components such as whitening agents coexist. Etidronic acid and / or a salt thereof is used as a general-purpose raw material for cosmetics. (For example, see Patent Document 5 and Patent Document 6) However, it is a gel cosmetic, and 1) an alkyl-modified carboxyvinyl polymer and / or a salt thereof; and 2) a carboxyvinyl polymer and / or a salt thereof. And 3) a water-swellable polymer and 4) etidronic acid and / or a salt thereof are not known at all, and such a combination can provide a gel preparation having excellent salt resistance. It was not known at all.

Japanese Patent Laid-Open No. 9-301852 JP 2004-123575 A JP 2002-193783 A JP 2000-327666 A JP 2003-238378 A Japanese National Patent Publication No. 9-506098

  The present invention has been made under such circumstances, and an object of the present invention is to provide a gel preparation having excellent salt resistance even when a whitening agent or the like coexists.

In view of such circumstances, the present inventors have intensively studied for a gel preparation having excellent salt resistance even when a whitening agent coexists. As a result, 1) alkyl-modified carboxyvinyl A preparation containing a polymer and / or a salt thereof, 2) a carboxyvinyl polymer and / or a salt thereof, 3) a water-swellable polymer, and 4) etidronic acid and / or a salt thereof has such characteristics. And found out that the invention was completed. That is, the present invention is as follows.
(1) Gel cosmetic, 1) alkyl-modified carboxyvinyl polymer and / or salt thereof, 2) carboxyvinyl polymer and / or salt thereof, 3) water-swellable polymer, 4) A gel-like cosmetic comprising etidronic acid and / or a salt thereof.
(2) The gel cosmetic according to (1), wherein the water-swellable polymer is an acrylic acid / starch graft polymer and / or a salt thereof.
(3) The gel cosmetic as described in (1) or (2), which is a body cosmetic.
(4) The cosmetic according to any one of (1) to (3), further comprising a whitening component and / or an anti-inflammatory component.
(5) The whitening component is ascorbic acid and / or a derivative thereof, arbutin and / or a salt thereof, ellagic acid and / or a salt thereof, tranexamic acid and / or a salt thereof, or 4-methoxysalicylic acid and / or a salt thereof. (4) Cosmetics as described in what.
(6) The cosmetic according to (4), wherein the anti-inflammatory component is stearyl glycyrrhetinate, dipotassium glycyrrhizinate or tranexamic acid and / or a salt thereof.
(7) The cosmetic according to any one of (4) to (6), which is a quasi-drug.
(8) The cosmetic according to (7), characterized in that it has an anti-inflammatory action and / or a whitening action in a packaging form.

  According to the present invention, it is possible to provide a gel preparation having excellent salt resistance even when a whitening agent and the like coexist.

(1) Alkyl-modified carboxyvinyl polymer and / or salt thereof which is an essential component of the cosmetic of the present invention The cosmetic of the present invention contains an alkyl-modified carboxyvinyl polymer and / or salt thereof as an essential component. It is characterized by that. As the alkyl group used for modification of the carboxyvinyl polymer, one having a single chain length of the alkyl group can be used, or one having a distribution can be used. It is particularly preferable to use one having a distribution. This is because such cosmetic raw materials are commercially available. The carbon number of the preferable alkyl group is 8-32, More preferably, it is 10-30. Such an alkyl-modified carboxyvinyl polymer may be one in which a crosslinking agent such as divinyl ether is added at the time of polymerization and partially crosslinked. Such alkyl-modified carboxyvinyl polymers already have commercial products, and it is preferable to purchase and use them. Preferred examples of such commercially available products include “Carbopol 1382”, “Pemlen TR-1”, “Pemlen TR-2” and the like sold by Goodrich. or. These salts include alkali metal salts such as sodium salt and potassium salt, alkaline earth metal salts such as calcium and magnesium, organic amine salts such as ammonium salt, triethanolamine salt and triethylamine salt, lysine salt, arginine salt and the like. Preferred examples include basic amino acid salts of These alkyl-modified carboxyvinyl polymers and / or salts can contain only one species or a combination of two or more species. In the cosmetic of the present invention, such an ingredient has an action of forming an aqueous gel having high salt resistance together with the carboxyvinyl polymer and / or a salt thereof and a water-swellable polymer. The preferable content of such components in the cosmetic of the present invention is 0.01 to 0.9% by mass and 0.05 to 0.5% by mass with respect to the total amount of the cosmetic in terms of the total amount. It is more preferable. This is because if the content is too small, the salt resistance may be impaired, and if the content is too large, the gel properties may be too hard and the usability may be impaired.

(2) Carboxyvinyl polymer and / or salt thereof The cosmetic of the present invention is characterized by containing a carboxyvinyl polymer and / or a salt thereof as an essential component. The carboxyvinyl polymer may be purchased and used as a raw material for cosmetics. The salts include alkali metal salts such as sodium salt and potassium salt, and alkaline earth metal salts such as calcium and magnesium. Preferred examples include organic amine salts such as ammonium salt, triethanolamine salt and triethylamine salt, and basic amino acid salts such as lysine salt and arginine salt. In the cosmetic of the present invention, the carboxyvinyl polymer and / or the salt thereof may contain only one species, or may contain two or more species in combination. In the cosmetic of the present invention, such an ingredient has an action of forming an aqueous gel having a high salt resistance together with an alkyl-modified carboxyvinyl polymer and / or a salt and a water-swellable polymer. The preferable content of such components in the cosmetic of the present invention is 0.01 to 0.9% by mass and 0.05 to 0.5% by mass with respect to the total amount of the cosmetic in terms of the total amount. It is more preferable. This is because if the content is too small, the salt resistance may be impaired, and if the content is too large, the gel properties may be too hard and the usability may be impaired.

(3) Water-swellable polymer which is an essential component of the cosmetic of the present invention The cosmetic of the present invention is characterized by containing a water-swellable polymer as an essential component. The water-swellable polymer that can be used in the cosmetic of the present invention can be used without particular limitation as long as it is a polymer that already has high water absorption and is known to swell when absorbed. I can do it. Examples of such a polymer include trimethylolpropane tri (β-acryloyloxypropionate), trimethylolpropane triacrylate or trimethylolpropane diacrylate, neopentyl glycol hydroxypivalate ester diacrylate, and cross-linked polyacrylamide. , Cross-linked polyvinyl alcohol, ethylene maleate adduct copolymer, cross-linked polyvinyl ether, hydroxypropylcellulose polyvinyl morpholine, (co) polymer of vinyl sulfonic acid derivatives, cross-linked poly (meth) acrylate, polymethylpyridine, hydrolyzed acrylonitrile polymerization Starch, (meth) acrylic acid starch polymer, cross-linked polyacrylate resin and the like can be suitably exemplified. Among these, a (meth) acrylic acid starch polymer is particularly preferred, and among them, sodium acrylate / starch graft polymer is particularly preferred. This product already has a commercial product, and such a commercial product can be purchased and used. As such a commercially available product, for example, “Sunfresh ST100”, “ST100MPS”, “ST100SP” and the like are preferable and can be exemplified. These are all commercially available from Sanyo Chemical Industries. In the cosmetic of the present invention, such a water-swellable polymer can contain only one species, or a combination of two or more species. In the cosmetic of the present invention, such an ingredient works with an alkyl-modified carboxyvinyl polymer and / or a salt thereof, a carboxyvinyl polymer and / or a salt thereof to make an aqueous gel structure having excellent salt resistance. The preferable content of such components in the cosmetic of the present invention is 0.001 to 0.1% by mass in total, and more preferably 0.005 to 0.05% by mass. This is because if the amount is too small, the effect of imparting salt resistance to the gel structure may not be exhibited, and if the amount is too large, the properties of the gel may be fragile.

(4) Etidronic acid and / or a salt thereof which are essential components of the cosmetic of the present invention The cosmetic of the present invention is characterized by containing etidronic acid and / or a salt thereof as an essential component. The salt of etidronic acid can be used without particular limitation as long as it is an alkali salt usually used in cosmetics, for example, alkali metal salts such as sodium salt and potassium salt, alkaline earth such as calcium and magnesium, etc. Preferred examples include organic amine salts such as metal salts, ammonium salts, triethanolamine salts and triethylamine salts, and basic amino acid salts such as lysine salts and arginine salts. In the cosmetic of the present invention, such a component can contain only one species, or two or more types can be contained in combination. In the cosmetic of the present invention, such a component has the effect of improving the salt resistance as well as improving the stability of the gel against heat. In particular, it increases salt resistance in usability. The maintenance of the gel structure itself in the presence of a salt consists of 1) alkyl-modified carboxyvinyl polymer and / or salt thereof, 2) carboxyvinyl polymer and / or salt thereof, and 3) water-swellable polymer. The combination of these three components alone is realized, but in the presence of salt, the gel structure is maintained for the first time by the presence of etidronic acid and / or its salt when stressed and scratched. In order to achieve such an effect, the total amount of such components is preferably 0.001 to 0.1% by mass, and preferably 0.005 to 0.05% by mass, based on the total amount of the cosmetic. It is more preferable. This is because if there are too few such components, the salt stability in the above-mentioned usability may be impaired, and if it is too much, the effect will reach its peak, and conversely, the stability of the system may be impaired. .

(5) Cosmetics of this invention The cosmetics of this invention contain the said essential component, It is an aqueous gel dosage form, It is characterized by the above-mentioned. Preferred examples of the aqueous gel preparation include those in a form in which a water-insoluble component such as an oily component is solubilized, or those that are slightly emulsified after emulsification. In the cosmetics of the present invention, in addition to such components, optional components usually used in cosmetics can be contained. Such optional ingredients include, for example, macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, hydrogenated coconut oil Oils such as hardened oil, mole, hardened castor oil, beeswax, candelilla wax, carnauba wax, ibotarou, lanolin, reduced lanolin, hard lanolin, jojoba wax, waxes, liquid paraffin, squalane, pristane, ozokerite, paraffin, ceresin, petrolatum , Hydrocarbons such as microcrystalline wax, higher fatty acids such as oleic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, undecylenic acid, cetyl alcohol, stearyl alcohol, isostearyl Alcohol, behenyl alcohol, octyldodecanol, higher alcohol such as myristyl alcohol, cetostearyl alcohol, cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebacate, cetyl lactate, malic acid Diisostearyl, di-2-ethylhexanoic acid ethylene glycol, dicaprate neopentyl glycol, di-2-heptylundecanoic acid glycerin, tri-2-ethylhexanoic acid glycerin, tri-2-ethylhexanoic acid trimethylolpropane, tri Synthetic ester oils such as trimethylolpropane isostearate and pentane erythritol tetra-2-ethylhexanoate, dimethylpolysiloxane, methylphenylpoly Loxane, linear polysiloxane such as diphenylpolysiloxane, cyclic polysiloxane such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexanesiloxane, amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, Oil agents such as silicone oil such as modified polysiloxane such as fluorine-modified polysiloxane, anionic surfactants such as fatty acid soap (sodium laurate, sodium palmitate, etc.), potassium lauryl sulfate, triethanolamine ether of alkyl sulfate, chloride Cationic surfactants such as stearyltrimethylammonium, benzalkonium chloride, laurylamine oxide, imidazoline-based amphoteric surfactants (2-cocoyl-2-imida Zolinium hydroxide-1-carboxyethyloxy disodium salt, etc.), betaine surfactants (alkyl betaine, amide betaine, sulfobetaine, etc.), amphoteric surfactants such as acylmethyltaurine, sorbitan fatty acid esters (sorbitan) Monostearate, sorbitan sesquioleate, etc.), glycerin fatty acids (glyceryl monostearate, etc.), propylene glycol fatty acid esters (propylene glycol monostearate, etc.), hardened castor oil derivatives, glycerin alkyl ethers, POE sorbitan fatty acid esters (POE sorbitan monooleate, polyoxyethylene sorbitan monostearate, etc.), POE sorbite fatty acid esters (POE-sorbitol monolaurate, etc.), POE glycerin fatty acid ester Tells (POE-glycerol monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2-octyldodecyl ether, etc.), POE alkyl phenyl ethers (POE nonylphenyl) Ethers, etc.), Pluronic types, POE / POP alkyl ethers (POE / POP2-decyltetradecyl ether, etc.), Tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), Nonionic surfactants such as sucrose fatty acid ester and alkyl glucoside, polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene Polyols such as recall, dipropylene glycol, diglycerin, isoprene glycol, 1,2-pentanediol, 2,4-hexylene glycol, 1,2-hexanediol, 1,2-octanediol, pyrrolidone carboxylic acid Moisturizing ingredients such as sodium, lactic acid, sodium lactate, guar gum, quince seed, carrageenan, galactan, gum arabic, pectin, mannan, starch, xanthan gum, curdlan, methylcellulose, hydroxyethylcellulose, carboxymethylcellulose, methylhydroxypropylcellulose, chondroitin sulfate , Dermatan sulfate, glycogen, heparan sulfate, hyaluronic acid, sodium hyaluronate, tragacanth gum, keratan sulfate, chondroitin, mucoitin sulfate, hyaluronan Droxyethyl guar gum, carboxymethyl guar gum, dextran, keratosulfuric acid, locust bean gum, succinoglucan, carolinic acid, chitin, chitosan, carboxymethylchitin, agar, polyvinyl alcohol, polyvinylpyrrolidone, sodium polyacrylate, polyethylene glycol, bentonite Thickeners such as mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, silicic anhydride (silica), aluminum oxide, barium sulfate, etc. May be treated, bengara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, bitumen, titanium oxide, zinc oxide inorganic pigments, surface may be treated, titanium mica, fish phosphorus foil, Pearl agents such as bismuth oxychloride, raked Red 202, Red 228, Red 226, Yellow 4, Blue 404, Yellow 5, Red 505, Red 230, Red 223, Orange 201, Red 213, Yellow 204 No., yellow 203, blue 1, green 201, purple 201, red 204, organic dyes such as polyethylene powder, polymethyl methacrylate, nylon powder, organopolysiloxane elastomer, and other organic powders, paraamino Benzoic acid UV absorbers, anthranilic acid UV absorbers, salicylic acid UV absorbers, cinnamic acid UV absorbers, benzophenone UV absorbers, sugar UV absorbers, 2- (2'-hydroxy-5'- UV absorbers such as t-octylphenyl) benzotriazole, 4-methoxy-4′-t-butyldibenzoylmethane, ethanol, Lower alcohols such as propanol, vitamin A or its derivatives, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 or its derivatives, vitamin B such as vitamin B12, vitamin B15 or its derivatives, α- Vitamin E such as tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin D, vitamin H, pantothenic acid, panthetin, pyrroloquinoline quinone and other vitamins, ascorbic acid and / or derivatives thereof, arbutin and / or Or whitening agents such as salts thereof, ellagic acid and / or salts thereof, tranexamic acid and / or salts thereof or 4-methoxysalicylic acid and / or salts thereof, or stearyl glycyrrhetinate, dipotassium glycyrrhizinate or tranexamic acid and Preferred examples include anti-inflammatory agents such as salts thereof. Of these, a whitening agent or an anti-inflammatory agent is particularly preferable. As the whitening agent, ascorbic acid and / or a derivative thereof, arbutin and / or a salt thereof, ellagic acid and / or a salt thereof, tranexamic acid and / or The salt thereof or 4-methoxysalicylic acid and / or a salt thereof can be preferably exemplified, and it is preferable to apply these salts as quasi drugs for suppressing melanin production or quasi drugs having anti-inflammatory action. . Preferred examples of the ascorbic acid derivative include ascorbic acid phosphate ester and / or salt thereof, glycoside of ascorbic acid such as ascorbic acid glucoside and / or salt thereof, and the like. Examples of salts of these whitening agents and anti-inflammatory agents include alkali metal salts such as sodium salts and potassium salts, alkaline earth metal salts such as calcium and magnesium, organic amine salts such as ammonium salts, triethanolamine salts and triethylamine salts. Preferred examples include basic amino acid salts such as lysine salt and arginine salt. The whitening agent can contain only one species or a combination of two or more species. The preferable content of the whitening agent is a total amount of 0.1 to 10% by mass, and more preferably 0.2 to 5% by mass with respect to the total amount of the cosmetic. The anti-inflammatory agent can contain only one species or a combination of two or more species. The preferable content of the anti-inflammatory agent in the cosmetic of the present invention is 0.01 to 5% by mass, and more preferably 0.02 to 1% by mass, based on the total amount of the cosmetic. When the cosmetic of the present invention is applied as a quasi-drug, it contains its active ingredients, whitening agent and / or anti-inflammatory agent, and whitening action, in other words, suppresses the production of melanin. It is preferable to clearly indicate on the packaging form that it has an effect of suppressing or suppressing inflammation. Many of these whitening agents or anti-inflammatory agents have ionization properties. Therefore, when blended in a normal aqueous gel preparation, the gel structure is loosened, which often impairs the stability or feeling during use. In the cosmetic of the present invention, such a defect does not exist in order to form a gel structure excellent in salt resistance. The cosmetic of the present invention can be produced by treating the above components according to a conventional method.

  Hereinafter, the present invention will be described in more detail with reference to examples, but it is needless to say that the present invention is not limited to such examples.

  According to the formulation shown below, the cosmetics of the present invention (quasi-drugs having an anti-inflammatory action and a melanin production inhibitory action) were prepared. That is, ingredients (a) and (b) were weighed, heated to 80 ° C., neutralized by gradually adding (b) to a under reduced pressure, and stirred and cooled to obtain a cosmetic 1 as an aqueous gel preparation. On the packaging of this product, there is a label indicating that it is a quasi-drug and a label indicating that it has an anti-inflammatory effect and a melanin production inhibitory effect.

<Test Example 1>
The stability of cosmetic 1 was tested. In the test, a cylindrical punching die having a height of 1 cm and a diameter of 5 cm is placed on a nonwoven fabric impregnated with physiological saline, and the cosmetic is discharged and filled therein, and the punching die is removed. Height was measured. In the same experiment, Comparative Example 1 in which “Carbopol 1382” of Cosmetic 1 was replaced with carboxyvinyl polymer, Comparative Example 2 in which carboxyvinyl polymer was replaced with “Carbopol 1382”, “Sunfresh ST-” of Cosmetic 1 Comparative Example 3 in which “100SP” was replaced with carboxyvinyl polymer and Comparative Example 4 in which “etidronic acid” was replaced with water were also carried out. The results are shown in Table 2. From this, it can be seen that the gel structure of the cosmetic of the present invention is excellent in salt resistance.

<Test Example 2>
The cosmetic was discharged in the same manner as in Test Example 1, the mold was removed, the center was lightly rubbed with a finger, and the height was measured in the same manner. The results are shown in Table 3. From this, it can be seen that the difference in salt tolerance becomes remarkable by applying physical stimulation to the gel structure. In other words, Comparative Example 4, which had a relatively high salt resistance in a stationary state due to a rubbing action such as application of a cosmetic, also significantly collapsed the gel structure, and the usability during use was impaired. I know that.

  Similarly to Example 1, cosmetic 2 of the present invention (quasi-drug having anti-inflammatory action and melanin production inhibitory action) was prepared according to the following formulation. When this product was tested by the method of Test Example 2, it was 0.9 cm.

  In the same manner as in Example 1, cosmetic 3 of the present invention (quasi-drug having anti-inflammatory action and melanin production inhibitory action) was prepared according to the following formulation. When this product was tested by the method of Test Example 2, it was 0.8 cm.

  As in cosmetics 1 to 3, cosmetic 4 (a quasi-drug that promoted anti-inflammatory action and melanin production inhibitory action) was prepared. The evaluation result of this example by Test Example 2 was 0.9 cm.

<Test Example 3>
Using cosmetics 1 to 4 and comparative examples 1 to 4, the appropriateness of the cosmetics for the body was evaluated by a specialized panel. The number of panelists was five, and they were Estesian. The evaluation is performed by massaging the decollete part of the model with a sample. Score 1 (difficult to massage), score 2 (difficult to massage somewhat), score 3 (possible) The score was 5 (easily massaged) and 5 (easy to massage). The average score is shown in Table 7. This shows that the cosmetic of the present invention is suitable for a body. This seems to be due to the fact that the body is more affected by sweat than the face, and for this reason, cosmetics with better salt resistance are needed.

  INDUSTRIAL APPLICABILITY The present invention can be applied to quasi-drugs for bodies that promote anti-inflammatory or melanin production-suppressing effects.

Claims (8)

Gel cosmetics, 1) alkyl-modified carboxyvinyl polymer and / or salt thereof, 2) carboxyvinyl polymer and / or salt thereof, 3) water-swellable polymer, 4) etidronic acid and Gel-like cosmetics characterized by containing a salt thereof. The gel cosmetic according to claim 1, wherein the water-swellable polymer is acrylic acid / starch graft polymer and / or a salt thereof. The gel cosmetic according to claim 1, wherein the gel cosmetic is a body cosmetic. The cosmetic according to any one of claims 1 to 3, further comprising a whitening component and / or an anti-inflammatory component. The whitening component is ascorbic acid and / or a derivative thereof, arbutin and / or a salt thereof, ellagic acid and / or a salt thereof, tranexamic acid and / or a salt thereof, or 4-methoxysalicylic acid and / or a salt thereof. The cosmetic according to claim 4. The cosmetic according to claim 4, wherein the anti-inflammatory component is stearyl glycyrrhetinate, dipotassium glycyrrhizinate or tranexamic acid and / or a salt thereof. The cosmetic according to any one of claims 4 to 6, which is a quasi-drug. The cosmetic according to claim 7, wherein the effect of having an anti-inflammatory action and / or a whitening action is displayed on the packaging form.