JP2006050910A - Fat metabolism-improving food composition, and food containing the same - Google Patents
Fat metabolism-improving food composition, and food containing the same Download PDFInfo
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
本発明は、血漿コレステロール濃度低下等の脂質代謝改善作用を顕著に有する脂質代謝改善用の食品組成物、およびこれを含有する食品に関する。 The present invention relates to a food composition for improving lipid metabolism, which has a remarkable effect of improving lipid metabolism such as lowering plasma cholesterol concentration, and a food containing the same.
高齢化社会を迎えた今日において、生活習慣病の予防は重要な課題となっている。生活習慣病の1つである心疾患等の循環器系疾患を予防するためには、血漿コレステロール濃度低下等の脂質代謝の改善が必要であることは周知の事実であり、脂質代謝改善作用を示す機能性食品が既に多数報告されている。 In today's aging society, prevention of lifestyle-related diseases has become an important issue. It is a well-known fact that it is necessary to improve lipid metabolism such as lowering plasma cholesterol level in order to prevent cardiovascular diseases such as heart disease, which is one of lifestyle-related diseases. Many functional foods have already been reported.
たとえば特許文献1には、ホエイタンパク質および/または該ホエイタンパク質加水分解物とリン脂質とを組み合わせることによって、これらを単独で用いるよりも、血清および肝臓の総コレステロールおよび肝臓中性脂肪を低下させることが可能な脂質代謝改善組成物が開示される。
For example,
また特許文献2には、大豆タンパク質、乳タンパク質、カルシウムおよびイソフラボンを有効成分として含有し、脂質代謝改善効果、血圧降下効果および骨強化効果を有し、しかも風味の良好な栄養組成物が開示される。しかし上記の効果、特に脂質代謝改善効果については未だ改善の余地がある。
わが国においては大豆の豆腐、豆乳等への加工後に大量のオカラが排出されており、オカラを大豆タンパク質含有食品の原料として再利用したいというニーズが存在する。また大豆には、大豆タンパク質、食物繊維の他、イソフラボン、サポニン等の生理活性成分が含まれるが、オカラ中にも上記の成分は豊富に含まれるため、オカラの健康改善用食品としての利用も検討されている。しかしオカラは栄養価が豊富である一方で腐敗が早いという欠点を有し、保存安定性を確保する工夫が必要となる。また、オカラを食品として再利用する場合、オカラ中に多量に含まれる食物繊維に由来するオカラ特有のざらつき感が食味上の欠点となる。 In Japan, a large amount of okara is discharged after processing soy beans into tofu, soy milk, etc., and there is a need to reuse okara as a raw material for soy protein-containing foods. In addition to soy protein and dietary fiber, soybean contains physiologically active ingredients such as isoflavones and saponins, but since the above ingredients are also abundant in okara, it can also be used as a food for improving health of okara. It is being considered. However, Okara has the disadvantage that it has a high nutritional value but has a high rate of spoilage. Therefore, it is necessary to devise a method for ensuring storage stability. Moreover, when reusing okara as a food, a rough feeling peculiar to okara derived from dietary fibers contained in a large amount in okara becomes a drawback in taste.
たとえば特許文献3には、おからと油とを、最終的に得られるおから(脱水状態)中の粗脂肪が20〜85w%となるような割合で水性溶媒中に分散した後、溶媒を除去することを特徴とする油含有おからが提案されている。特許文献3おいては、該油含有おからが、製麺、製パン、製菓、ソーセージ、蒲鉾等の他、健康食品、医薬品用の組成物として有用である旨が開示される。しかし特許文献3はおからを食品組成物として再利用する際の食味の向上を課題としているため健康改善作用については殆ど考慮されておらず、十分な健康改善作用が得られるとは言えない。
本発明は、上記の課題を解決し、豆腐、豆乳等の製造において生成する副産物または搾油後において生成する油糧残渣であるオカラを有効利用することによって廃棄物の再利用に寄与するとともに、たとえば血漿コレステロール濃度低下作用等の、より顕著な脂質代謝改善作用を発揮することが可能な脂質代謝改善用の食品組成物、およびこれを含有する食品を提供することを目的とする。 The present invention solves the above-mentioned problems, contributes to the reuse of waste by effectively using the okara which is a by-product generated in the production of tofu, soy milk, etc. or the oil residue generated after oil extraction, It is an object of the present invention to provide a food composition for improving lipid metabolism capable of exhibiting a more remarkable lipid metabolism improving action such as a plasma cholesterol concentration lowering action, and a food containing the same.
本発明の脂質代謝改善用の食品組成物は、乾燥オカラと、EPA(エイコサペンタエン酸)および/またはDHA(ドコサヘキサエン酸)を含有する魚油とを組み合わせて用いることを特徴とする。乾燥オカラは単独でも血漿コレステロール濃度低下作用等の脂質代謝改善作用を有するが、脂質代謝改善用の食品組成物としての効果には未だ向上の余地があった。本発明においては、所定量のEPAおよび/またはDHAを乾燥オカラと組み合わせて用いることにより、該組み合わせによる相乗効果が生じ、さらに顕著な脂質代謝改善効果を有する食品組成物を得ることができる。 The food composition for improving lipid metabolism of the present invention is characterized by using dry okara in combination with fish oil containing EPA (eicosapentaenoic acid) and / or DHA (docosahexaenoic acid). Dried okara alone has a lipid metabolism improving action such as a plasma cholesterol concentration reducing action, but there is still room for improvement in the effect as a food composition for improving lipid metabolism. In the present invention, by using a predetermined amount of EPA and / or DHA in combination with dried okara, a synergistic effect is produced by the combination, and a food composition having a remarkable lipid metabolism improving effect can be obtained.
すなわち本発明は、乾燥オカラの10〜50質量%と魚油とを含有する食品組成物であって、該魚油中のEPAおよび/またはDHAの含有量が、該乾燥オカラに対して0.5〜5.0質量%の範囲内である脂質代謝改善用の食品組成物に関する。 That is, the present invention is a food composition containing 10 to 50% by mass of dry okara and fish oil, wherein the content of EPA and / or DHA in the fish oil is 0.5 to The present invention relates to a food composition for improving lipid metabolism within a range of 5.0% by mass.
本発明の食品組成物における魚油は、乾燥オカラに対して1〜20質量%の範囲内で含有されることが好ましい。また魚油は、EPAおよび/またはDHAを合計で30〜50質量%含有する魚油であることが好ましい。 The fish oil in the food composition of the present invention is preferably contained within a range of 1 to 20% by mass with respect to dry okara. Moreover, it is preferable that fish oil is a fish oil containing 30-50 mass% of EPA and / or DHA in total.
本発明の食品組成物にはデンプンおよび/または小麦粉が好ましく含有される。 The food composition of the present invention preferably contains starch and / or flour.
本発明において配合される乾燥オカラは、イソフラボンとタンパク質とを含有し、該乾燥オカラ中の該イソフラボンのアグリコン換算含有量が40mg/100g以上であり、かつ該乾燥オカラ中の該タンパク質の含有量が20〜30質量%の範囲内であることが好ましい。 The dry okara blended in the present invention contains isoflavone and protein, the isoglycone content of the isoflavone in the dry okara is 40 mg / 100 g or more, and the content of the protein in the dry okara is It is preferable to be within the range of 20 to 30% by mass.
本発明はまた、上記の脂質代謝改善用の食品組成物を含有してなる食品に関する。 The present invention also relates to a food comprising the above-described food composition for improving lipid metabolism.
本発明によれば、乾燥オカラと、所定量のEPAおよび/またはDHAを含有する魚油とを組み合わせて用いることにより、通常廃棄物として処理されるオカラの有効利用が可能であるとともに、より顕著な脂質代謝改善作用を有する食品組成物およびこれを含有する食品の提供が可能となる。 According to the present invention, by using dry okara in combination with fish oil containing a predetermined amount of EPA and / or DHA, it is possible to effectively use okara that is usually treated as waste, and more prominently. It is possible to provide a food composition having an action of improving lipid metabolism and a food containing the same.
本発明の脂質代謝改善用の食品組成物においては、乾燥オカラと、所定量のEPAおよび/またはDHAを含有する魚油との組み合わせにより脂質代謝改善作用が付与される。本発明におけるオカラとは、大豆を原料として豆乳または豆腐を製造する工程において、水に浸して膨潤させた吸水大豆を加熱、磨砕して生成させた「呉(ゴ)」をろ過し、固液分離して得られる固形状の副産物、または大豆の搾油後の油糧残渣を指す。また、本発明における乾燥オカラとは、上記で得られる固形状の副産物または油糧残渣を乾燥させたものであって、特に水分の含有量が12質量%以下であるものを指す。 In the food composition for improving lipid metabolism of the present invention, a lipid metabolism improving action is imparted by a combination of dried okara and fish oil containing a predetermined amount of EPA and / or DHA. Okara in the present invention refers to “go” produced by heating and grinding water-absorbing soybeans that have been soaked and swollen in water in the process of producing soy milk or tofu using soybeans as a raw material. It refers to solid by-products obtained by liquid separation, or oil residues after soybean oil extraction. The dry okara in the present invention refers to a product obtained by drying the solid by-product or oil residue obtained above and having a water content of 12% by mass or less.
大豆の成分のうち、水溶性タンパク質、脂質、水溶性食物繊維、ミネラルの多くは豆乳または豆腐に移行するが、オカラ中にも多量の栄養成分が残留し、特に不溶性タンパク質、不溶性食物繊維は豊富に存在する他、生理活性作用を有するイソフラボン、サポニン等の成分も含まれる。 Among soybean components, most of water-soluble proteins, lipids, water-soluble dietary fibers, and minerals are transferred to soy milk or tofu, but a large amount of nutrients remain in okara, especially insoluble proteins and insoluble dietary fibers. In addition, components such as isoflavones and saponins having physiological activity are also included.
生オカラには、通常、水分が約75〜80質量%、タンパク質が約5〜6質量%、脂質が約4質量%、炭水化物が約10〜14質量%、ミネラルが約1質量%含まれる。ここで炭水化物の大部分は食物繊維である。一方、乾燥オカラに通常含まれる水分は約10質量%以下であり、タンパク質が約25質量%、炭水化物が約50質量%(食物繊維としては約40質量%)含まれる。すなわち、乾燥オカラには、原料である大豆由来のタンパク質、食物繊維が高濃度で含まれる。本発明の食品組成物においては、乾燥オカラを用いることによって、加工性を向上させるとともに、食品組成物中にタンパク質、食物繊維等の有用成分を高濃度で含有させることができる。 Raw okara usually contains about 75-80% by weight of water, about 5-6% by weight of protein, about 4% by weight of lipid, about 10-14% by weight of carbohydrates, and about 1% by weight of minerals. Here most of the carbohydrates are dietary fiber. On the other hand, the moisture normally contained in dry okara is about 10% by mass or less, about 25% by mass of protein, and about 50% by mass of carbohydrate (about 40% by mass as dietary fiber). That is, dried okara contains a high concentration of soybean-derived protein and dietary fiber as raw materials. In the food composition of the present invention, by using dried okara, processability is improved and useful components such as protein and dietary fiber can be contained in the food composition at a high concentration.
本発明の食品組成物は、乾燥オカラの10〜50質量%と魚油とを含有し、該魚油中のEPA(エイコサペンタエン酸)および/またはDHA(ドコサヘキサエン酸)の含有量が、該乾燥オカラの0.5〜5.0質量%の範囲内とされる。食品組成物中の乾燥オカラの含有量が10質量%以上であれば、血漿コレステロール濃度低下作用等の脂質代謝改善作用が所望の程度得られるため好ましく、50質量%以下、さらに30質量%以下、さらに20質量%以下であれば、ざらつき感等の食味の低下を防止するとともに、吸水等による加工性または保存安定性の低下も防止できる点で好ましい。また、EPAおよび/またはDHAの含有量が乾燥オカラの0.5質量%以上であれば、脂質代謝改善作用が所望の程度得られるため好ましい。なお、EPAおよび/またはDHAの含有量が乾燥オカラの5.0質量%程度であれば、脂質代謝改善作用は十分得られ、5.0質量%よりEPAおよび/またはDHAの含有量を多くしても脂質代謝改善作用はあまり変化しないことから、製造コストの観点では5.0質量%以下、さらに3.0質量%以下、さらに2.0質量%以下とされることが好ましい。 The food composition of the present invention contains 10-50% by mass of dry okara and fish oil, and the content of EPA (eicosapentaenoic acid) and / or DHA (docosahexaenoic acid) in the fish oil is It is set within the range of 0.5 to 5.0% by mass. If the dry okara content in the food composition is 10% by mass or more, a lipid metabolism improving action such as a plasma cholesterol concentration reducing action is preferably obtained to a desired degree, and is preferably 50% by mass or less, and further 30% by mass or less. Furthermore, if it is 20 mass% or less, it is preferable at the point which can prevent the fall of tastes, such as a rough feeling, and can also prevent the fall of workability or storage stability by water absorption etc. Further, if the content of EPA and / or DHA is 0.5% by mass or more of the dry okara, it is preferable because a lipid metabolism improving effect can be obtained to a desired degree. In addition, if the content of EPA and / or DHA is about 5.0% by mass of dry okara, a lipid metabolism improving effect is sufficiently obtained, and the content of EPA and / or DHA is increased from 5.0% by mass. However, since the lipid metabolism improving action does not change so much, it is preferably 5.0% by mass or less, more preferably 3.0% by mass or less, and further 2.0% by mass or less from the viewpoint of production cost.
本発明の食品組成物においては、EPA、DHAのいずれを用いても同様の脂質代謝改善作用を発現させることができる。よって、EPAおよび/またはDHAの含有量は両者の合計によって制御されれば良く、EPA、DHAそれぞれの配合量は限定されないが、たとえば、乾燥オカラに対してEPAが0.5質量%以上5.0質量%以下、DHAが0.5質量%以上5.0質量%以下とされることが好ましい。 In the food composition of the present invention, the same lipid metabolism improving action can be expressed by using either EPA or DHA. Therefore, the content of EPA and / or DHA may be controlled by the sum of both, and the blending amounts of EPA and DHA are not limited, but for example, EPA is 0.5% by mass or more to dry okara. It is preferable that 0 mass% or less and DHA be 0.5 mass% or more and 5.0 mass% or less.
EPAおよびDHAはいずれも一般に魚油中に豊富に含有される。本発明においては、食品組成物中に魚油を配合することにより、EPAおよび/DHAの含有量が所定の範囲内となるよう制御する。特に、魚油としては、EPAおよび/またはDHAの濃度の合計が30質量%以上、さらに35質量%以上、また50質量%以下、さらに40質量%以下となるようにEPAおよび/またはDHAを含有する精製魚油を用いることが好ましい。 Both EPA and DHA are generally abundant in fish oil. In the present invention, the content of EPA and / DHA is controlled to be within a predetermined range by adding fish oil to the food composition. In particular, fish oil contains EPA and / or DHA so that the total concentration of EPA and / or DHA is 30% by mass or more, further 35% by mass or more, 50% by mass or less, and further 40% by mass or less. It is preferable to use purified fish oil.
本発明においては、EPAおよび/またはDHAの含有量を所定の範囲内に調整する際、魚油を乾燥オカラに対して1質量%以上となるように配合することが好ましく、また20質量%以下、さらに15質量%以下、さらに10質量%以下となるように配合することが好ましい。このような魚油にはEPAおよび/またはDHAが比較的高濃度で含まれることとなるため、魚油中の脂質代謝改善作用に寄与しない成分による食品組成物の製品安定性や加工性の低下の危険性を回避できる。 In the present invention, when adjusting the content of EPA and / or DHA within a predetermined range, the fish oil is preferably blended so as to be 1% by mass or more with respect to the dry okara, and 20% by mass or less, Furthermore, it is preferable to mix | blend so that it may become 15 mass% or less, and also 10 mass% or less. Since such fish oil contains EPA and / or DHA at a relatively high concentration, there is a risk of deterioration in product stability and processability of food compositions due to components that do not contribute to lipid metabolism improving action in fish oil. Sex can be avoided.
本発明において好ましく配合される魚油としては、たとえば、アジ、アンコウ、イカナゴ、イサキ、イトヨリ、イワシ、カツオ、カマス、カレイ、キス、サケ、サバ、サワラ、サンマ、シタビラメ、スズキ、タラ、トビウオ、ニシン、ハタハタ、ハマチ、ハモ、ヒラマサ、ヒラメ、フグ、ブリ、マグロ、マス、マダイ、マナガツオ、メバル等から採取される魚油が挙げられる。これらの魚から採取される魚油を、EPAとDHAとの濃度の合計が30〜50質量%の範囲内となるように精製することが好ましい。 Fish oils preferably blended in the present invention include, for example, horse mackerel, anglerfish, eelfish, isaki, oyster, sardine, skipjack, barracuda, flounder, kiss, salmon, mackerel, sawara, saury, scallop, sea bass, cod, flying fish, herring , Fish oil collected from grouper, yellowtail, sea bream, Japanese flounder, Japanese flounder, pufferfish, yellowtail, tuna, trout, red sea bream, red bonito, mabaru and the like. It is preferable to refine | purify the fish oil extract | collected from these fishes so that the sum total of the density | concentration of EPA and DHA may exist in the range of 30-50 mass%.
なお、精製魚油を得る方法としては、たとえば脱ガム、脱水処理、脱酸処理、脱色処理、脱ろう処理、脱臭処理、ろ過処理等の工程によって魚油を精製する方法等が好ましく採用され得る。 In addition, as a method of obtaining refined fish oil, the method of refine | purifying fish oil by processes, such as a degumming process, a dehydration process, a deoxidation process, a decoloring process, a dewaxing process, a deodorizing process, a filtration process, etc. can be employ | adopted preferably, for example.
本発明の食品組成物には、乾燥オカラ、EPAおよび/またはDHAを含む魚油、の他に、デンプン、小麦粉等のつなぎ材料、さらに、ビタミンEをはじめとして、香辛料、糖アルコール、茶カテキン、ごま種子成分、トマト成分等に例示される抗酸化物質、等を配合することができる。 The food composition of the present invention includes dried okara, fish oil containing EPA and / or DHA, as well as connecting materials such as starch and flour, as well as vitamin E, spices, sugar alcohol, tea catechin, sesame Antioxidants such as seed components and tomato components can be blended.
食品組成物にデンプンおよび/または小麦粉が配合される場合、乾燥オカラとEPAおよび/またはDHAとを混合する際にデンプンや小麦粉がつなぎ材料として作用することによって食品組成物の製造が容易になるとともに、たとえば動物用の栄養組成物としてそのまま使用できるため好ましい。また、たとえばビタミンEを配合することによりEPAおよび/またはDHAの酸化が防止されるため食品組成物の保存安定性が向上する。 When starch and / or flour is blended in the food composition, the starch or flour acts as a connecting material when the dry okara and EPA and / or DHA are mixed, thereby facilitating the production of the food composition. For example, it is preferable because it can be used as it is as a nutritional composition for animals. Further, for example, by adding vitamin E, oxidation of EPA and / or DHA is prevented, so that the storage stability of the food composition is improved.
乾燥オカラに含まれるイソフラボン、サポニン、大豆タンパク質は、油脂の酸化防止作用を有するため、不飽和脂肪酸であるEPAおよびDHAの酸化を抑制するという役割にも寄与する。 Since isoflavones, saponins, and soy proteins contained in dried okara have an antioxidant effect on fats and oils, they contribute to the role of suppressing the oxidation of unsaturated fatty acids, EPA and DHA.
さらに、本発明において乾燥オカラは魚油が有する魚油臭をマスキングするという役割にも寄与する。よって、本発明の食品組成物は日常食品に対して適用される場合にも食品そのものの食味をほとんど損なわないという利点を有する。 Furthermore, in the present invention, dry okara also contributes to the role of masking the fish oil odor possessed by fish oil. Therefore, the food composition of the present invention has an advantage that the taste of the food itself is hardly impaired even when applied to everyday food.
本発明の食品組成物は、血漿コレステロール濃度低下効果等の脂質代謝改善作用を有することを特徴とする。血漿コレステロールは、LDL(悪玉)コレステロールとHDL(善玉)コレステロールとに大きく分類される。血漿LDLコレステロール濃度が高くなると虚血性心疾患等の進行が促進されることが多くの疫学的調査から分かっている。一方、HDLコレステロールは血管壁に蓄積したコレステロールを除去し、血管へコレステロールを運び込むLDLコレステロールと拮抗するため、虚血性心疾患等の予防効果を有することが分かっている。 The food composition of the present invention is characterized by having an action of improving lipid metabolism such as a plasma cholesterol concentration lowering effect. Plasma cholesterol is roughly classified into LDL (bad) cholesterol and HDL (good) cholesterol. Numerous epidemiological studies have shown that the progression of ischemic heart disease and the like is promoted when the plasma LDL cholesterol concentration increases. On the other hand, since HDL cholesterol removes cholesterol accumulated in the blood vessel wall and antagonizes LDL cholesterol that carries cholesterol into blood vessels, it is known to have a preventive effect on ischemic heart disease and the like.
本発明の食品組成物は、血漿HDLコレステロール濃度を低下させる作用は殆ど有しないが、後述する機構により血漿LDLコレステロール濃度を選択的に低下させることができる。すなわち、本発明の食品組成物は、血漿総コレステロール濃度の低下効果を有するとともに、LDL(悪玉)コレステロール/HDL(善玉)コレステロールの存在比を改善する効果を有する。 Although the food composition of the present invention has almost no action of lowering plasma HDL cholesterol concentration, it can selectively lower plasma LDL cholesterol concentration by a mechanism described later. That is, the food composition of the present invention has an effect of lowering the total plasma cholesterol concentration and an effect of improving the abundance ratio of LDL (bad) cholesterol / HDL (good) cholesterol.
乾燥オカラに含まれる大豆タンパク質、イソフラボン、食物繊維、サポニン等は、本発明において生理活性成分として作用する。本発明においては、食品組成物中に乾燥オカラを所定濃度となるように配合し、これらの生理活性成分の寄与によって、血漿総コレステロール濃度低下効果、LDL(悪玉)コレステロール/HDL(善玉)コレステロールの存在比の改善効果、に代表される脂質代謝改善効果を得ることを特徴とする。 Soy protein, isoflavone, dietary fiber, saponin and the like contained in dried okara act as physiologically active ingredients in the present invention. In the present invention, dry okara is blended in the food composition so as to have a predetermined concentration, and due to the contribution of these physiologically active ingredients, the plasma total cholesterol concentration lowering effect, LDL (bad) cholesterol / HDL (good) cholesterol It is characterized by obtaining an improvement effect of lipid metabolism represented by an improvement effect of abundance ratio.
βコングリシニン等の大豆タンパク質、および食物繊維は、コレステロールおよびその代謝物である胆汁酸と結合し、該コレステロールおよび該胆汁酸の吸収を抑制し、体外への排出を促進する作用を有する。これにより、肝臓へのコレステロールおよび胆汁酸の輸送量が減少し、血漿コレステロール濃度が低下する。また、βコングリシニンの分解物のペプチドとイソフラボンは、組織のLDLレセプターを活性化するため、血漿LDLコレステロール濃度を低下させ、脂質代謝を改善する作用を有する。 Soy protein such as β-conglycinin and dietary fiber bind to cholesterol and its metabolite bile acid, suppress the absorption of the cholesterol and bile acid, and promote the excretion outside the body. Thereby, the amount of cholesterol and bile acids transported to the liver is reduced, and the plasma cholesterol concentration is lowered. In addition, β-conglycinin degradation product peptides and isoflavones activate the tissue LDL receptor, and thus have a function of lowering plasma LDL cholesterol concentration and improving lipid metabolism.
一方、EPAおよびDHAもまた脂質代謝改善作用を有する生理活性成分であって、血漿総コレステロール濃度低下、LDL(悪玉)コレステロール/HDL(善玉)コレステロールの存在比の改善に寄与する。すなわち、魚油に含まれるn−3系多価不飽和脂肪酸であるEPAおよびDHAは、転写調節因子SREBP−1の作用を抑制し、脂肪酸合成を抑制するため、肝臓からのリポタンパク質の分泌量を低下させ、血漿コレステロール濃度を低下させ、脂質代謝を改善する作用を有する。 On the other hand, EPA and DHA are also physiologically active components having an action of improving lipid metabolism, and contribute to the reduction of plasma total cholesterol concentration and the abundance ratio of LDL (bad) cholesterol / HDL (good) cholesterol. That is, EPA and DHA, which are n-3 polyunsaturated fatty acids contained in fish oil, suppress the action of the transcriptional regulatory factor SREBP-1 and suppress fatty acid synthesis. Has the effect of lowering, lowering plasma cholesterol levels and improving lipid metabolism.
上記のように、乾燥オカラ中の生理活性成分と、EPAおよび/またはDHAとは、異なる機構によって血漿コレステロール濃度を低下させる作用を有する。本発明の食品組成物においては、乾燥オカラ中の生理活性成分と、EPAおよび/またはDHAとの共存によって相乗効果が生じる。これにより、EPAおよび/またはDHAの含有量が比較的低濃度であっても、乾燥オカラと、EPAおよび/またはDHAとをそれぞれ単独で用いた場合の生理活性作用の単なる和ではなく、両者の相乗効果による著しい脂質代謝改善作用の向上が実現される。 As described above, the physiologically active ingredient in dry okara and EPA and / or DHA have an action of lowering plasma cholesterol concentration by different mechanisms. In the food composition of the present invention, a synergistic effect is produced by the coexistence of a physiologically active ingredient in dried okara and EPA and / or DHA. Thus, even if the content of EPA and / or DHA is relatively low, it is not a mere sum of the physiological activity when dry okara and EPA and / or DHA are used alone, Significant improvement in lipid metabolism improving action by synergistic effect is realized.
本発明において配合される乾燥オカラの形状は限定されず、配合される食品組成物の種類や形状によって適宜選択され得るが、たとえば粉末状を有する場合食品組成物の製造が容易であるため好ましい。粉末の粒子径は、50μm以上、さらに60μm以上とされることが好ましく、この場合、製造コストの上昇を防止できる。また、粒子径は125μm以下、さらに80μm以下とされることが好ましく、この場合、加工性に優れるとともに、ざらつき感による食味の低下が防止できる。 The shape of the dry okara to be blended in the present invention is not limited and can be appropriately selected depending on the type and shape of the blended food composition. For example, when it has a powder form, it is preferable because the food composition can be easily produced. The particle diameter of the powder is preferably 50 μm or more, and more preferably 60 μm or more. In this case, an increase in manufacturing cost can be prevented. Moreover, it is preferable that a particle diameter shall be 125 micrometers or less, and also 80 micrometers or less, and in this case, while being excellent in workability, the fall of the taste by a rough feeling can be prevented.
乾燥オカラの粒子径は、乾燥オカラの粉砕回数、粉砕時間等の制御により所望の範囲内に調整することができる。本品の食品組成物がたとえば麺類等の食味の滑らかさが重視される用途に適用される場合には、粒子径が比較的小さく調整されることが好ましい。通常粒子径が125μm以下であれば、デンプンや小麦粉等の他の配合成分と均一かつ容易に混合することができる。なお平均粒子径の調整は、粉砕した乾燥オカラをメッシュにより分級する方法等により行なうことができる。 The particle diameter of the dry okara can be adjusted within a desired range by controlling the number of times the dry okara is pulverized, the pulverization time, and the like. When the food composition of the present product is applied to an application in which smoothness of taste is important, such as noodles, it is preferable that the particle size is adjusted to be relatively small. In general, when the particle size is 125 μm or less, it can be uniformly and easily mixed with other compounding components such as starch and wheat flour. The average particle diameter can be adjusted by a method of classifying pulverized dry okara with a mesh or the like.
乾燥オカラは通常イソフラボンを豊富に含有するが、本発明においては、イソフラボンのアグリコン換算含有量がたとえば40mg/100g以上、さらに50mg/100g以上、さらに60mg/100g以上である場合、血漿コレステロール濃度低下作用等の脂質代謝改善作用に優れる食品組成物が得られるため好ましい。またイソフラボンのアグリコン換算含有量がたとえば80mg/100g以下、さらに70mg/100g以下である場合、製造コストが安価である点で好ましい。 Dry okara usually contains abundant isoflavones, but in the present invention, when the content of isoflavones in terms of aglycone is, for example, 40 mg / 100 g or more, further 50 mg / 100 g or more, and further 60 mg / 100 g or more, plasma cholesterol concentration lowering action It is preferable because a food composition excellent in lipid metabolism improving action such as the above can be obtained. Further, when the content of isoflavone in terms of aglycone is, for example, 80 mg / 100 g or less, and further 70 mg / 100 g or less, it is preferable in terms of low production cost.
乾燥オカラ中の大豆タンパク質の含有量が、たとえば20質量%以上、さらに25質量%以上とされる場合、血漿コレステロール濃度低下作用等の脂質代謝改善作用に優れる食品組成物が得られるため好ましい。また、大豆タンパク質の含有量が35質量%以下、さらに30質量%以下とされる場合、製造コストが安価である点で好ましい。 When the content of soy protein in the dried okara is, for example, 20% by mass or more, and further 25% by mass or more, a food composition excellent in lipid metabolism improving action such as plasma cholesterol concentration reducing action is preferable. Moreover, when content of soybean protein shall be 35 mass% or less and also 30 mass% or less, it is preferable at the point that manufacturing cost is cheap.
本発明で配合される乾燥オカラ中の大豆タンパク質のうち、80〜100質量%のタンパク質が加熱により変性凝固していることが好ましい。この場合加工性および保存安定性に優れる食品組成物が得られる。 Of the soybean protein in the dry okara blended in the present invention, 80 to 100% by mass of protein is preferably denatured and solidified by heating. In this case, a food composition having excellent processability and storage stability can be obtained.
本発明で配合される乾燥オカラの吸水率は、3ml/g以上、さらに4ml/g以上とされることが好ましく、この場合、乾燥オカラが比較的安価に製造できる。また吸水率は6ml/g以下、さらに5ml/g以下であることが好ましく、この場合、食品組成物の吸水による物理的特性の変化が生じる危険性が少ない。 The water absorption of the dry okara blended in the present invention is preferably 3 ml / g or more, and more preferably 4 ml / g or more. In this case, the dry okara can be produced at a relatively low cost. Further, the water absorption is preferably 6 ml / g or less, more preferably 5 ml / g or less. In this case, there is little risk that the physical properties change due to water absorption of the food composition.
本発明において乾燥オカラを得る工程の例について以下に説明する。本発明の乾燥オカラは、生オカラまたは搾油大豆を乾燥させる工程を経て製造することができるが、生オカラの乾燥によって得られた未調整乾燥オカラ中のイソフラボンのアグリコン換算含有量を測定する工程、および、該未調整乾燥オカラ中のイソフラボンのアグリコン換算含有量を調整する工程、を含むことが好ましい。なおイソフラボンのアグリコン換算含有量の測定は、たとえば高速液体クロマトグラフィー(HPLC)等により行なわれることができる。 An example of a process for obtaining dried okara in the present invention will be described below. The dried okara of the present invention can be produced through the process of drying raw okara or oiled soybean, but the process of measuring the aglycone equivalent content of isoflavones in unadjusted dried okara obtained by drying raw okara, And adjusting the aglycone equivalent content of isoflavones in the unadjusted dry okara. The measurement of the content of isoflavones in terms of aglycone can be performed by, for example, high performance liquid chromatography (HPLC).
生オカラまたは搾油大豆から未調整乾燥オカラを得る工程における乾燥は、熱風乾燥によって行なわれることが好ましい。搾汁直後に熱風乾燥することにより、生オカラ中の有効成分の変性を低減することができ、微生物が繁殖する危険性も効果的に抑制される。 The drying in the step of obtaining the unadjusted dry okara from raw okara or oiled soybean is preferably performed by hot air drying. By drying with hot air immediately after squeezing, it is possible to reduce the denaturation of active ingredients in raw okara, and the risk of microbial propagation is also effectively suppressed.
未調整乾燥オカラを得る工程においては、乾燥温度および加熱時間を調整することにより、用途に応じて未調整乾燥オカラの吸水量を調整する工程を含むことが好ましい。この場合製造ラインに特別な装置を増設することなく比較的容易に未調整乾燥オカラの吸水量を調整できる。 The step of obtaining the unadjusted dry okara preferably includes a step of adjusting the water absorption of the unadjusted dry okara according to the use by adjusting the drying temperature and the heating time. In this case, the water absorption amount of the unadjusted dry okara can be adjusted relatively easily without adding a special device to the production line.
未調整オカラ中のイソフラボンのアグリコン換算含有量を調整する工程は、あらかじめ生オカラまたは乾燥オカラから食品添加可能な有機溶媒により抽出された有機溶媒溶解成分を、未調整乾燥オカラに添加する工程を含むことが好ましい。有機溶媒溶解成分にはイソフラボンが含まれるため、上記の方法によれば、比較的簡便な操作で未調整オカラ中のイソフラボンの含有量を所望の濃度に調整することができる。 The step of adjusting the aglycone equivalent content of isoflavones in unadjusted okara includes the step of adding, to the unadjusted dry okara, an organic solvent-dissolved component extracted in advance from raw okara or dried okara with an organic solvent that can be added to food. It is preferable. Since the organic solvent-soluble component contains isoflavone, according to the above method, the content of isoflavone in unadjusted okara can be adjusted to a desired concentration by a relatively simple operation.
上記の方法により得られた乾燥オカラの平均粒子径を適宜所望の範囲内に調整した後、たとえば小麦粉、デンプン等と混合し、EPAおよび/またはDHAを含有する魚油を配合し、さらにビタミンE等の添加剤を加え、加熱等の加工処理を行なうことにより、本発明の食品組成物とすることができる。 After adjusting the average particle size of the dried okara obtained by the above method appropriately within a desired range, for example, it is mixed with flour, starch, etc., blended with fish oil containing EPA and / or DHA, vitamin E, etc. The food composition of the present invention can be obtained by adding the additive and performing processing such as heating.
なお、本発明において食品組成物を調製する際には、乾燥オカラを直接他の配合成分と混合しても良いが、あらかじめ水分を添加して生オカラの状態に近づけた後に他の成分と混合しても良い。この場合、乾燥オカラの特に食物繊維の分散不均一が防止されることにより、食品としての食味がより良好となる。 In addition, when preparing a food composition in the present invention, dry okara may be directly mixed with other ingredients, but after adding water in advance to bring it into a raw okara state, it is mixed with other ingredients You may do it. In this case, the taste as a food becomes better by preventing the uneven dispersion of the dried fiber, particularly the dietary fiber.
本発明の食品組成物を日常食品に適用する場合、製造工程における大豆の磨砕時に発生するリポキシゲナーゼ活性を熱失活させることによって、乾燥オカラの有する大豆特有の臭いを低減させることができる。また調理操作や食品組成物の種類、配合量等の選択によっても大豆特有の臭いは低減され得る。 When the food composition of the present invention is applied to daily foods, the odor peculiar to soybeans in dried okara can be reduced by thermally inactivating the lipoxygenase activity generated during the grinding of soybeans in the production process. Moreover, the smell peculiar to soybeans can be reduced also by selection of cooking operation, the kind of food composition, and the amount of blending.
本発明の食品組成物は、麺類、パン、ケーキ、お好み焼き、から揚げ、マッシュポテト、スイートポテト、白玉、ニョッキ等の食品類に練り込んで使用できる他、スープ類、ジュース類等に混合することも好ましい。また、上記の日常食品以外にも、たとえばデンプンと混合すること等によって動物飼料としても好適に使用できる。さらに、本発明の食品組成物は、粉末状、顆粒状、ペレット状、シート状等に成形された健康食品としても好適に提供され得る。 The food composition of the present invention can be used by kneading into foods such as noodles, bread, cakes, okonomiyaki, fried, mashed potatoes, sweet potatoes, white balls, gnocchi, etc., and can also be mixed with soups, juices, etc. preferable. In addition to the above-mentioned daily foods, it can be suitably used as animal feed by mixing with starch, for example. Furthermore, the food composition of the present invention can be suitably provided as a health food molded into a powder, granule, pellet, sheet or the like.
<実施例>
以下、実施例を挙げて本発明をより詳細に説明するが、本発明はこれらに限定されるものではない。
<Example>
EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated in detail, this invention is not limited to these.
(実施例1〜3、比較例1〜3)
乾燥オカラ(イソフラボンのアグリコン換算含有量60mg/100g、タンパク質含有量25質量%)、EPAおよび/またはDHA、コレステロールをそれぞれ表1に示す濃度で含有するカゼイン・デンプン飼料を、脂質代謝改善用食品組成物、および比較の食品組成物として5週齢のSD系雄ラットに1週間習慣的に摂取させた。
(Examples 1-3, Comparative Examples 1-3)
Casein / starch feed containing dried okara (isoflavone aglycone equivalent content 60 mg / 100 g, protein content 25% by mass), EPA and / or DHA and cholesterol at the concentrations shown in Table 1, respectively, to improve lipid metabolism As a comparative food composition, a 5-week-old SD male rat was habitually ingested for 1 week.
摂取前と1週間摂取後との血漿総コレステロール濃度を測定し、摂取前に対する1週間摂取後の血漿総コレステロール濃度低下率(%)を求めた。結果を表1に示す。なお実施例1〜3および比較例1〜3において、飼料の摂取量およびラットの体重変化挙動はほぼ同様であり、上記実施例および比較例においては十分量の飼料が摂取されていることが確認された。 The plasma total cholesterol concentration before intake and after intake for 1 week was measured, and the decrease rate (%) of plasma total cholesterol concentration after intake for 1 week relative to before intake was determined. The results are shown in Table 1. In Examples 1 to 3 and Comparative Examples 1 to 3, the amount of feed intake and the weight change behavior of the rats were almost the same, and it was confirmed that a sufficient amount of feed was ingested in the above Examples and Comparative Examples. It was done.
EPA、DHAを含有しない比較例2、3において血漿総コレステロール濃度低下効果が認められなかったのに対し、乾燥オカラ含有率を10質量%以上、EDAとDHAとを合計で0.2質量%含有する実施例1〜3では、良好な血漿総コレステロール濃度低下効果が見られた。乾燥オカラ含有率が5質量%の比較例1は、実施例1〜3と比べて血漿総コレステロール濃度低下効果が劣っていた。 In Comparative Examples 2 and 3 not containing EPA or DHA, the plasma total cholesterol concentration lowering effect was not observed, but the dry okara content was 10% by mass or more, and EDA and DHA were combined in a total of 0.2% by mass. In Examples 1 to 3, good plasma total cholesterol concentration lowering effects were observed. Comparative Example 1 having a dry okara content of 5% by mass was inferior in plasma total cholesterol concentration lowering effect as compared with Examples 1 to 3.
(実施例4、比較例4〜6)
乾燥オカラ(イソフラボンのアグリコン換算含有量60mg/100g、タンパク質含有量25質量%)、EPAおよび/またはDHA、コレステロールをそれぞれ表2に示す濃度で含有するカゼイン・デンプン飼料を、脂質代謝改善用食品組成物、および比較の食品組成物として5週齢のSD系雄ラットに8週間習慣的に摂取させ、血漿HDLコレステロール濃度を1週間ごとに測定した。なお実施例4および比較例4〜6において、飼料の摂取量およびラットの体重変化挙動はほぼ同様であり、上記実施例および比較例においては十分量の飼料が摂取されていることが確認された。
(Example 4, Comparative Examples 4-6)
A casein / starch feed containing dried okara (isoflavone aglycone equivalent content 60 mg / 100 g, protein content 25% by mass), EPA and / or DHA and cholesterol at the concentrations shown in Table 2, respectively, for improving lipid metabolism As a comparative food composition, 5-week-old SD male rats were habitually ingested for 8 weeks, and plasma HDL cholesterol concentration was measured every week. In Example 4 and Comparative Examples 4 to 6, the amount of feed intake and the weight change behavior of rats were almost the same, and it was confirmed that a sufficient amount of feed was ingested in the above Examples and Comparative Examples. .
図1は、ラットの血漿総コレステロール値の変化を示す図であり、図2は、ラットの血漿HDL−コレステロール値の変化を示す図である。図2から分かるように、実施例4および比較例4〜6における血漿HDL−コレステロール値は4週間摂取後を除いて大きな差は見られなかった。一方、図1から分かるように、実施例4および比較例4〜6における血漿総コレステロール値には顕著な差が見られた。乾燥オカラ、EPAおよび/またはDHAのいずれも含まない比較例6と比べて、乾燥オカラを含む比較例4、EPAおよび/またはDHAを含む比較例5で血漿総コレステロール値の上昇量が少なく、乾燥オカラ、EPAおよび/またはDHAをともに含む実施例4では、比較例4および比較例5と比べてさらに血漿総コレステロール値の上昇量が少なかった。 FIG. 1 is a diagram showing changes in rat plasma total cholesterol levels, and FIG. 2 is a diagram showing changes in rat plasma HDL-cholesterol levels. As can be seen from FIG. 2, the plasma HDL-cholesterol levels in Example 4 and Comparative Examples 4 to 6 were not significantly different except after intake for 4 weeks. On the other hand, as can be seen from FIG. 1, there was a significant difference in plasma total cholesterol levels in Example 4 and Comparative Examples 4-6. Compared with Comparative Example 6 which does not contain any of dry okara, EPA and / or DHA, Comparative Example 4 which contains dry okara and Comparative Example 5 which contains EPA and / or DHA have a small increase in the total plasma cholesterol level, and the drying In Example 4 containing both okara, EPA and / or DHA, the amount of increase in plasma total cholesterol level was smaller than that in Comparative Example 4 and Comparative Example 5.
以上の結果より、乾燥オカラと、EPAおよび/またはDHAを含有する魚油とを所定の濃度で含有させることにより、優れた脂質代謝改善作用を有する脂質代謝改善用の食品組成物を得ることが可能であることが分かる。 From the above results, it is possible to obtain a food composition for improving lipid metabolism having an excellent action for improving lipid metabolism by containing dried okara and fish oil containing EPA and / or DHA at a predetermined concentration. It turns out that it is.
今回開示された実施の形態および実施例はすべての点で例示であって制限的なものではないと考えられるべきである。本発明の範囲は上記した説明ではなくて特許請求の範囲によって示され、特許請求の範囲と均等の意味および範囲内でのすべての変更が含まれることが意図される。 It should be understood that the embodiments and examples disclosed herein are illustrative and non-restrictive in every respect. The scope of the present invention is defined by the terms of the claims, rather than the description above, and is intended to include any modifications within the scope and meaning equivalent to the terms of the claims.
本発明の食品組成物は、乾燥オカラと、EPAおよび/またはDHAを所定の濃度で含有する魚油とを配合することによって、該乾燥オカラと、EPAおよび/またはDHAとの相乗効果により、顕著な脂質代謝改善作用を有する食品組成物、およびこれを含有する食品の提供が可能となる。また通常廃棄物として処理されるオカラの有効利用に寄与できる。 The food composition of the present invention is prominent due to the synergistic effect of the dried okara and EPA and / or DHA by blending the dried okara and fish oil containing EPA and / or DHA at a predetermined concentration. It is possible to provide a food composition having an action of improving lipid metabolism and a food containing the same. Moreover, it can contribute to the effective use of Okara that is usually treated as waste.
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WO2008053902A1 (en) | 2006-10-31 | 2008-05-08 | Fuji Oil Company, Limited | Food or beverage containing highly unsaturated fatty acid, and process for production thereof |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008053902A1 (en) | 2006-10-31 | 2008-05-08 | Fuji Oil Company, Limited | Food or beverage containing highly unsaturated fatty acid, and process for production thereof |
JP2015091246A (en) * | 2008-07-18 | 2015-05-14 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | Method for enhancing quality of life of senior animal |
CN117860801A (en) * | 2024-03-07 | 2024-04-12 | 南方海洋科学与工程广东省实验室(湛江) | Fish oil traditional Chinese medicine compound with comprehensive blood lipid regulating effect and preparation method and application thereof |
CN117860801B (en) * | 2024-03-07 | 2024-05-28 | 南方海洋科学与工程广东省实验室(湛江) | Fish oil traditional Chinese medicine compound with comprehensive blood lipid regulating effect and preparation method and application thereof |
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