JP2006036759A - Insect repellent and insect-repelling device and method using the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an insect repellent which is highly effective to repel harmful insects, is quite safe for human health, is highly stable, and is capable of being simply used even at home. <P>SOLUTION: The insect repellent contains a silicone compound as an active ingredient. The insect repellent is embodied by one wherein the silicone compound is volatile. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to an insect repellent, an insect repellent, and an insect repellent method, and more specifically, an insect repellent, an insect repellent, and an insect repellent that prevent damage caused by pests such as fiber pests such as moths and moths, and grain pests such as scallop Regarding the method.

  Conventionally, various insect repellents against various pests have been proposed. In recent years, pyrethroid compounds and the like are known and widely used as insect repellents (for example, Patent Document 1). However, these pyrethroid insect repellents were not fully satisfactory in terms of safety and stability.

  It is also known that highly safe natural ingredients and food ingredients are used as insect repellents. For example, an insect repellent for rice using horseradish, mustard, ginger, pepper, garlic, etc. (Patent Document 2), an insect repellent for fiber products containing cineol as an active ingredient (Patent Document 3), l-carvone or l -An aromatic insect repellent (Patent Document 4) containing an essential oil containing carvone and linalool and / or anethole as active ingredients is known.

  However, since these insect repellents use chemicals used in natural products or foods, there is no problem with safety, but the insect repellent effect against pests is weak and sufficient insect repellent effect is obtained. Had no problem.

On the other hand, it is also known to blend a silicone compound in an insect repellent. However, the reason why the silicone compound is blended in the insect repellent is to suppress the volatilization of a specific volatilizing drug component and aim at long-term sustainability of the insect repellent effect (Patent Documents 5 and 6). In the pest repellent for human body, prevention of volatilization from the skin, prevention of chafing and run-out due to sweat, improved durability and feeling of use (Patent Document 7), and prevention of discoloration and alteration of specific drugs These were intended (Patent Document 8), and none of them utilized the insecticidal effect of the silicone compound itself.
JP-A-63-203649 Japanese Patent Laid-Open No. 6-038678 JP-A-57-062024 JP-A-55-129204 JP-A-53-107418 JP-A-63-3316706 JP-A-4-244001 JP-A-7-206615

  Accordingly, it is desired to develop an insect repellent that has a sufficient insect repellent effect against pests, is highly safe and stable to the human body, and can be easily used in general households. Is the subject of the present invention.

  The present inventor has conducted intensive research to solve the above-mentioned problems. As a result, it has been found that some silicone compounds that have been used in various cosmetics and industrial products have an excellent insecticidal effect. As a result, the present invention has been achieved.

  That is, the present invention provides an insect repellent comprising a silicone compound as an active ingredient.

  Moreover, this invention provides the insect repellent which has the structure which discharge | releases the said insect repellent in an environment by normal temperature natural transpiration, heating transpiration, ventilation transpiration, fumigation, or spraying.

  The silicone compound, which is an active ingredient of the insect repellent of the present invention, exhibits an excellent insect repellent effect against pests and pest eggs, and has been conventionally used in cosmetics and the like. It is safe and highly stable. Therefore, the insect repellent of the present invention can be easily used in general households.

In the present invention, “insect protection” is a concept including the following actions.
(1) Inhibitory action to suppress hatching of pest eggs (2) Insecticidal action of young larvae to kill young larvae hatched (3) Repellent action to repel pests (4) Insecticidal action to kill pests ( 5) Growth inhibitory action that suppresses the growth of pests

  The insect repellent of this invention contains the 1 type (s) or 2 or more types of a silicone type compound as the active ingredient.

  In the insect repellent of the present invention, the silicone compound used as an active ingredient is not particularly limited as long as it has an insect repellent effect in the above sense, and has high volatility when used by being released into the environment. Those having low volatility are preferred when used in contact with a pest or a pest egg in a liquid or solid state. Here, the volatility means a property of vaporizing under normal temperature or a certain heating condition. When released into the environment and used, those having high volatility, that is, those having a boiling point of 350 ° C. or less at normal pressure, more preferably 300 ° C. or less, and particularly preferably 250 ° C. or less are preferred. Conversely, when used in contact with a pest or a pest egg in a liquid or solid state, those having low volatility, that is, those having a boiling point of 250 ° C. or higher at normal pressure, more preferably those of 300 ° C. or higher, A temperature of 350 ° C. or higher is particularly preferable.

  Moreover, even if it is a non-volatile silicone type compound, if this silicone type compound can be made to contact a pest or a pest egg, an insecticidal effect can be exhibited and it can be used as an insecticide.

［式中、Ｒ_１、Ｒ_２及びＲ_３は異なっていてもよい水素原子、フェニル基又は式（２）

−Ｘ−Ｒ' ・・・・・（２）
（式中、Ｘは炭素数１〜１０のアルキレン基又は酸素原子を示し、Ｒ'は水素原子、フェニル基、エポキシ基、アミノ基、カルボキシル基、水酸基、トリフルオロメチル基、トリメチルシリル基、−（ＯＣ_２Ｈ_４）_ａ−（ＯＣ_３Ｈ_６）_ｂＯＲ''（ａ及びｂは異なっていてもよい０〜１０の自然数であり、Ｒ''は炭素数１〜１０のアルキル基である）又は−ＮＨ−（ＣＨ_２）_ｃ−ＮＨ_２（ｃは１〜１０の自然数である）を示す）を示し、ｍ、ｎ及びｏは異なっていてもよい０〜１００の自然数を示す］ In the insect repellent of the present invention, examples of the silicone compound preferably used as an active ingredient include those represented by the following formula (1).

[Wherein R ₁ , R ₂ and R ₃ may be different from each other, a hydrogen atom, a phenyl group or formula (2)

-XR '(2)
(In the formula, X represents an alkylene group having 1 to 10 carbon atoms or an oxygen atom, and R ′ represents a hydrogen atom, phenyl group, epoxy group, amino group, carboxyl group, hydroxyl group, trifluoromethyl group, trimethylsilyl group, — ( OC ₂ H ₄ ) _a- (OC ₃ H ₆ ) _b OR ″ (a and b are natural numbers of 0 to 10 which may be different, and R ″ is an alkyl group having 1 to 10 carbon atoms) Or —NH— (CH ₂ ) _c —NH ₂ (where c is a natural number of 1 to 10), and m, n, and o are 0 to 100, which may be different.]

（式中、Ｒは水素原子、炭素数１〜１０のアルキル基又はフェニル基を示し、ｓは０〜１００の自然数を示す） Of the silicone compounds represented by the formula (1), particularly preferred are those represented by the following formula (5) or formula (6).

(In the formula, R represents a hydrogen atom, an alkyl group having 1 to 10 carbon atoms, or a phenyl group, and s represents a natural number of 0 to 100)

（式中、ｔは１〜１００の自然数を示す）

(Wherein t represents a natural number of 1 to 100)

Among these, in formula (5), it is more preferable that R is a methyl group. These are not particularly limited, but from the viewpoint of easy preparation of insect repellents, it is preferable to use those having a kinematic viscosity at 25 ° C. of 500 mm ² / sec or less, and those having 10 mm ² / sec or less are used. It is particularly preferred.

［式中、Ｙ及びＺは異なっていてもよい炭素数１〜１０のアルキレン基、フェニレン基又は単結合を示し、Ｒ_４はメチル基又は水酸基を示し、Ｒ_５はメチル基又は−（ＣＨ_２）_ｄ−ＮＨ−（ＣＨ_２）_ｅ−ＮＨ_２（ｄ及びｅは異なっていてもよい１〜１０の自然数である）を示し、ｐ及びｑは異なっていてもよい０〜１００の自然数を示す］ Moreover, the silicone type compound represented by following formula (3) is also preferable as an active ingredient of this invention insect repellent.

[Wherein, Y and Z each represent an optionally substituted alkylene group having 1 to 10 carbon atoms, a phenylene group or a single bond, R ₄ represents a methyl group or a hydroxyl group, and R ₅ represents a methyl group or — (CH ₂ ) _D -NH- (CH ₂ ) _e -NH ₂ (d and e are natural numbers of 1 to 10 which may be different), and p and q represent natural numbers of 0 to 100 which may be different. ]

（式中、Ｒ_６はメチル基又はフェニル基を示し、Ｒ_７はメチル基、フェニル基又はビニル基を示し、ｒは３〜２０の自然数を示す） Furthermore, a silicone compound represented by the following formula (4) is also preferable as an active ingredient of the insect repellent of the present invention.

(In the formula, R ₆ represents a methyl group or a phenyl group, R ₇ represents a methyl group, a phenyl group, or a vinyl group, and r represents a natural number of 3 to 20)

Of the compounds represented by formula (4), particularly preferred are compounds in which r is a natural number of 4-6. Moreover, it is particularly preferable that both R ₆ and R ₇ are methyl groups.

  Among the silicone compounds, specific examples of those represented by the formula (1) include, for example, hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane, dimethylpolysiloxane, methylhydrogenpolysiloxane, and methylphenyl. Examples thereof include polysiloxane, 3,3-diphenylhexamethylpolysiloxane, polyoxyethylenemethylpolysiloxane copolymer, poly (oxyethylene-oxypropylene) methylpolysiloxane copolymer, and laurylmethicone copolyol. These specific product names include SF8411, SF8413, SF8416, SF8417, SF8418, SF8428, SF8419, SF8421, SF8410, SF8451, SF8452, FS1265, SH200, SH203, SH556, SH3746, SH230, H37S, H8S SH3772M, SH3771M, SH3773M, SH3775M, and SH1107 (all manufactured by Toray Dow Corning Silicone Co., Ltd.).

  Specific examples of the silicone compound represented by the formula (3) include, for example, aminomethylaminopropylsiloxane dimethylsiloxane copolymer and the like. Specific examples of these product names include SF8427, SM8704C (both manufactured by Toray Dow Corning Silicone Co., Ltd.).

  Furthermore, specific examples of the silicone compound represented by the formula (4) include, for example, hexamethylcyclotrisiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, 1,3,5,7-tetramethyltetra List vinylcyclotetrasiloxane, 1,3,5,7,9-pentamethylpentavinylcyclopentasiloxane, octaphenylcyclotetrasiloxane, 1,3,5,7,9-pentamethylpentaphenylcyclopentasiloxane, etc. Specific examples of these trade names include SH244, SH245, SH344, DC345, and DC246 (all manufactured by Toray Dow Corning Silicone Co., Ltd.).

  The silicone compound is preferably blended so that the concentration thereof is 0.1 to 100% by mass (hereinafter abbreviated as “%”) with respect to the whole insect repellent, and 1 to 100%. It is particularly preferable to blend in More preferably, it is 10 to 100%.

  The insect repellent of the present invention is produced by using one or two or more of the above silicone compounds as active ingredients in combination and formulating them by a conventional method. The silicone compound used in the insect repellent of the present invention can be variously selected depending on the pest to be applied, the purpose, the form of the agent, the method of use and the like.

  In addition, the insect repellent of the present invention may be formulated as the above-mentioned silicone compound as a single active ingredient, but is preferably prepared by blending an appropriate substance and formulating it by a conventional method. There is no limitation in particular as a dosage form of the insect repellent of this invention, It can be set as forms, such as a liquid agent, a gel agent, and a solid agent.

  The insect repellent of the present invention, which is a liquid dosage form, includes a silicone compound alone or a mixture of other insect repellent ingredients in combination with a silicone compound alone or other insect repellent ingredients added thereto. A form dissolved in an appropriate solvent may be used.

  The solvent that can be used to prepare the liquid agent is not particularly limited, and a conventionally known liquid carrier can be used, but it is preferable to use a substance that is highly safe for the body. Specifically, water; hydrocarbon compounds such as hexane and paraffin; methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, 2-methyl-1-propanol, 2-methyl-2 Alkyl alcohols such as propanol, pentanol, hexanol, heptanol, octanol, nonanol, decanol; alkenyl alcohols such as allyl alcohol; aromatic ring-containing alcohols such as benzyl alcohol; phenols such as eugenol; halogens such as chloroform Hydrocarbon compounds; ether compounds such as diethyl ether and diethylene glycol diethyl ether; ketone compounds such as acetone; fatty acid compounds such as acetic acid and oleic acid; acetates, propionates, benzoates Ester compounds such as ethylene; glycol compounds such as ethylene glycol and propylene glycol; glycol ether compounds such as 2-phenoxyethanol and 3-methyl-3-methoxybutanol; vegetable oils such as sesame oil, linoleic oil and salad oil These 1 type or 2 types or more are mixed and used.

  These solvents are preferably blended in an amount of 0.1 to 99.9%, particularly preferably 1 to 99%, based on the whole insect repellent. More preferably, it is 10 to 90%.

  In preparing this solution, a surfactant can be added as necessary. Examples of the surfactant that can be used include conventionally known surfactants such as cationic surfactants, anionic surfactants, amphoteric surfactants, and nonionic surfactants. It can be used alone or in combination of two or more.

  In addition, the insect repellent of the present invention can be made into a solid or sheet-like solid agent by impregnating and supporting the above liquid agent on a suitable carrier. The carrier to be supported is not particularly limited, and examples thereof include wood, paper, woven fabric, non-woven fabric, silica, talc, activated carbon, silica gel, zeolite, cellulose beads, activated carbon, ceramic and the like.

  Furthermore, the insect repellent of this invention can be made into the gel agent which gelatinized the above-mentioned liquid agent with the gelatinizer. Examples of the gelling agent include conventionally known ones such as carrageenan, gellan gum, agar, gelatin, guar gum, pectin, locust bean gum, xanthan gum, sodium alginate, cellulose derivative, dibenzylidene-D-sorbitol, hydroxypropyl. Superabsorbent polysaccharides such as modified polysaccharides, inulin stearate, sodium acrylate and the like can be used, and these can be used alone or in combination of two or more.

  A preferred method of using the insect repellent of the present invention obtained as described above includes a method in which a silicone compound contained as an active ingredient in the insect repellent of the present invention is released into the environment. Examples of the method for releasing into the environment include a method of spontaneously evaporating the insect repellent of the present invention such as a liquid agent, a solid agent and a gel agent, and a method of forcibly evaporating. Examples of the method of forcibly evaporating include transpiration by heating, transpiration by air blowing, and transpiration by fumigation. Moreover, you may use the method by spraying, etc. as a method of releasing in an environment.

  Among the above-mentioned forced transpiration methods, transpiration by heating, for example, as disclosed in Japanese Utility Model Publication No. 2-78077 etc., sucks up an insect repellent housed in a chemical solution bottle with a suction core, the upper part of the suction core, etc. An insecticide is impregnated into a heating evaporator that is evaporated by heating with a heater, or a mat-like impregnated body as disclosed in Japanese Utility Model Laid-Open No. 1-116072, and the mat is placed on the heater. It can be carried out using a heating transpiration device or the like adapted to evaporate by being placed on.

  In addition, transpiration by blowing is provided with a medicine holder and a blower as disclosed in, for example, JP-A-11-308955, and an insect repellent is brought into contact with the air current generated by the blower. Can be carried out using a fan-type insect repellent device or the like that discharges water into the environment from the discharge port.

  Further, the transpiration by fumigation is, for example, an organic foaming agent such as an azo compound such as azodicarbonamide, a nitroso compound, a hydrazide compound and an insect repellent in a container having an upper opening as disclosed in Japanese Utility Model Publication No. 54-148267. A storage chamber containing the agent is formed, and the bottom of the storage chamber is heated by a heating means, using a fumigation device that evaporates the insect repellent using nitrogen gas, carbon dioxide gas, etc. generated by decomposition of the foaming agent. be able to.

  The transpiration by spraying can be performed by using a sprayer and spraying a liquid or using an aerosol using an appropriate propellant.

  The insect repellent of the present invention is preferably used by installing and applying it to a space such as a chiffon, closet, closet, kitchen, toilet, living room, entrance, etc., so that the silicone compound as an active ingredient is released into the environment. Can be insect-proof.

  As described above, the insect repellent used to effectively release the insect repellent of the present invention into the environment, as described above, the natural repellent of the present invention by natural transpiration, heat transpiration, air transpiration, fumigation or spraying. Insect repellents having a structure for release into the environment are preferred. Examples of such insect repellents include a structure having a discharge port, a holding part for holding an insect repellent provided in the structure, a heater or a blower installed in the vicinity of the holding part. Vessel.

  Another preferred method of using the insect repellent of the present invention includes a method in which a silicone compound is used in contact with a pest or a pest egg in a liquid or solid state. In this case, the insect repellent effect can be exerted by the contact of a pest and the like with the installed insect repellent silicone compound.

  Specific examples of the method of use include a method in which a pest or a pest egg is brought into contact with a treated product treated with the above-described liquid preparation containing a silicone compound. Examples of products to be treated here include fiber products, plastic film products, and the like. Specific examples include clothes, curtains, sheets, clothing insect repellent covers, and the like. Examples of the treatment method include a method in which a silicone compound is kneaded into the base material of the product, or a method of adhering to the base material by coating, impregnation, printing, spraying, or the like.

  The above method is preferable because the silicone compound, which is an active ingredient of the insect repellent of the present invention, acts as a hatching inhibitor or an insecticide for young larvae.

  In addition to the silicone compound as described above, other conventionally known insect repellent components may be blended with the insect repellent of the present invention, whereby a further excellent insect repellent effect can be exhibited. Examples of these other insect repellent components include pyrethroid compounds such as empentrin, transfluthrin, allethrin, phenothrin, profluthrin, and eminence; compounds such as paradichlorobenzene, naphthalene, 2-phenoxyethanol; camphor, pepper, horseradish, perilla, Plant extracts such as cardamom, nutmeg, clove, coriander, sage, rosemary, basil, caraway, thyme, eucalyptus, laurel, citronella, anise, orange, lavender, essential oil, allicin, capsaicin, perilaldehyde, tea tree oil, pine oil A thing etc. are mentioned, These 1 type may be used independently and can also be used in combination of 2 or more type.

  As an example of a preferable thing among the insect repellents of this invention, the insect repellent which combined the silicone type compound and the said plant extract from the point with especially high safety | security can be mentioned. In addition, when the insect repellent of the present invention is used in contact with a pest or a pest egg in a liquid or solid state, or acts as a hatching inhibitor or a young larvae insecticide, a pyrethroid compound, etc. It is also preferable to add the above-mentioned other known insect repellent ingredients, but when the insect repellent of the present invention is used after being released into the environment, it does not contain a pyrethroid compound or the like from the viewpoint of safety. Insect repellents comprising only the compound as the sole insect repellent active ingredient are preferred.

  The insect repellent of the present invention described above has an insect repellent effect against various pests generated in the home, particularly insects. The pests for which the present insect repellent is effective are not particularly limited, but specific examples thereof include pods such as wolfberry, sawtooth moth, wolfberry, weevil, weevil, granary weevil, scorpion worm, himemaru, katobushimushi, etc. Pests of the eyes; Pests of the Lepidoptera such as Noshimekoga, Bakuga, Nomemadarameiga, Suikomamadarameiga, Hachimitsuga, Gaimitsuna Riga, Yumemadarameiga, Kakumnekokunusu, Iga, Koiga; Pests such as cockroach, reucofair maderae, chaban cockroach, aceta domestics, etc .; pests of insects such as Horficula auricularis; termite pests such as reticulitermes; lice such as human lice Pests such as bed bugs, rhodonius prolixus, triatoma infestans, etc .; Hymenoptera pests such as house spiders, Lasius nigel, hornets, etc .; Examples include dipteran pests such as the butterflies, lobsters, fly flies, and flies; adults, fleas, larvae, and eggs of fleas such as the murine flea and the chironomid.

  EXAMPLES Next, although an Example is given and this invention is demonstrated in more detail, this invention is not restrict | limited at all by these Examples.

Example 1
A filter paper impregnated with 10 mg of the test substance shown in Table 1 is placed in a metal cage having a diameter of 4 cm, and this is placed at the center of a glass lidded container having an internal volume of 0.5 liter. A 2.5-cm square surge with 20 iga eggs, which are clothing pests one day after egg laying, was placed on. After storage for 14 days under conditions of temperature 25 ° C and relative humidity 60% RH, open the container lid, count the number of hatched eggs, and if hatched, the young larvae immediately after hatching Determined. When N is the number of young larvae that survived, the percentage of the total number of “number of eggs that did not hatch + number of young larvae that died” (hereinafter referred to as “insect repellent rate”) is:
Insect repellent rate (%) = 100 × (20−N) / 20
The values for each test substance are shown in Table 2. In addition, the blank which did not put any test substance was used.

Example 2
The insect repellent rate was calculated by the same test method as in Example 1 except that the eggs were replaced with the eggs of maiga, a grain pest. The results are shown in Table 3.

Example 3
Place a 2.0 cm square surge impregnated with 5% by mass of the test substance in a square surge into a petri dish with a diameter of 4.5 cm. 30 eggs of Himekatsuobushimushi were placed. After storage for 7 days under conditions of 25 ° C. and 60% RH, the number of young larvae (N) that survived in the same manner as in Example 1 was determined, and the insect control rate was calculated using the following formula: did. The results are shown in Table 4.
Insect control rate (%) = 100 × (30−N) / 30

Example 4
The target pest eggs of Example 3 were tested in the same manner as in Example 3 except that the eggs of the pine beetle were changed to eggs of Nomadamearaga and the impregnation amount of the test substance was 15% by mass with respect to the surge mass. Went. The results are shown in Table 5.

Example 5
(Insecticidal tests against adult mosquitoes)
Fifty female adult mosquitoes (3 to 4 days after emergence) were anesthetized with diethyl ether and lined up on cardboard, and 5 μg of each sample was dropped on the chest back plate. Thereafter, the test insects were transferred to a clean waist-high petri dish, covered with syrup cotton, covered with a wire mesh, and stored at a temperature of 25 ° C. The life and death of the test insects after 24 hours were determined, and the lethality was calculated as a percentage of the total number of dead insects. The results are shown in Table 6.

Example 6
(Insecticidal test against larvae of Culex pipiens)
A 10 ppm aqueous suspension of Samples 1 and 4 was prepared, and 200 ml of each was placed in a waist-high petri dish. Into this, 25 final larvae of Culex pipiens were introduced, stored at a temperature of about 25 ° C., and the number of dead worms after 24 hours was measured. The fine worms were dead and the hatched ones were excluded. Similar tests were performed in duplicate, and the total number of dead insects was taken as the number of dead insects in the drug-treated area. The number of dead insects in the control group was determined in the same manner as in the drug-treated group, with no drug added, and the mortality was calculated using the following formula. The results are shown in Table 7.
Lethality rate (%) = 100 × (Na−Nb) / (Nt−Nb)
Nt: Total number of insects in each group Na: Number of dead insects in the drug-treated group Nb: Number of dead insects in the control group

Example 7
(Insecticidal test against housefly adults)
Samples 1 and 4 were prepared by diluting 10-fold with normal hexane. 50 adult female flies (3-4 days after emergence) were anesthetized with diethyl ether and lined up on cardboard, and placed on the chest backplate. 5 μg of each prepared sample was dropped per animal. Thereafter, the test insects were transferred to a clean waist-high petri dish, covered with syrup cotton, covered with a wire mesh, and stored at a temperature of about 25 ° C. The life and death of the test insects after 24 hours were determined, and the number of dead insects in the drug-treated area was determined. In addition, the thing which dripped only the normal hexane which does not contain a chemical | medical agent was made into the control, the number of dead insects of the control group was calculated | required like the chemical treatment group, and the lethality was computed using the following formula. The results are shown in Table 8.
Lethality rate (%) = 100 × (Na−Nb) / (Nt−Nb)
Nt: Total number of insects in each group Na: Number of dead insects in the drug-treated group Nb: Number of dead insects in the control group

Example 8
(Insecticidal test against housefly larvae)
A 1000 ppm water suspension of Samples 1 and 4 was prepared, and 200 ml of each was placed in a waist-high petri dish. Twenty-five housefly larvae were introduced into this, and the number of dead worms after 24 hours was measured at a temperature of about 25 ° C. and a relative humidity of 90%. The fine worms were dead and the hatched ones were excluded. A similar test was performed in duplicate to determine the total number of dead insects, which was used as the number of dead insects in the drug-treated area. The number of dead insects was determined in the same manner as in the drug-treated section, and the mortality rate was calculated using the following formula. The results are shown in Table 9.
Lethality rate (%) = 100 × (Na−Nb) / (Nt−Nb)
Nt: Total number of insects in each group Na: Number of dead insects in the drug-treated group Nb: Number of dead insects in the control group

Example 9
(Insecticidal test against German cockroach larvae)
In order to prevent the larvae from creeping up, 10 to 20 cockroach larvae within 6 days after hatching were gently knocked out in a petri dish of 9 cm in diameter and 6 cm in height, coated with butter 4 cm from the inner wall. It was. Place a test plate that was uniformly coated with 0.5 ml of the 30% diethyl ether solution of Sample 1 and Sample 1 on a 10 cm square plywood plate and air-dried for 50 to 60 minutes. The test insect was brought into contact with the drug application surface by inverting it. Thereafter, the state of knockdown with the passage of time was observed, and the elapsed time (KT ₅₀ ) when ₅₀ % of the test insects were knocked out and the elapsed time (KT ₉₀ ) when 90% of the test insects were knocked out were measured. In addition, the mortality after 24 hours was calculated. The test was performed in triplicate, the elapsed time of knockout was averaged, and the mortality was calculated as a percentage of the total number of dead insects using the total number. The results are shown in Table 10.

Example 10
(Insecticidal test against adult German cockroaches)
In order to prevent the test insects from crawling, 30 adult female German cockroaches were placed in a petri dish with a diameter of 9 cm and a height of 6 cm coated with butter about 4 cm from the inner wall. A test plate in which 0.5 ml of Sample 1 was uniformly applied to a 10 cm square plywood plate was placed on a waist-high petri dish with the sample application surface down, and this was inverted to bring the test insect into contact with the drug application surface. The lethality after 24 hours was calculated as a percentage of the total number of dead insects. The results are shown in Table 11.

Example 11
Insect repellents were prepared as in Formulation Examples 1 to 6 below.

Formulation Example 1
Aerosol:
An aerosol was prepared by filling the following formulation into a commercially available 200 ml aerosol can.
Active ingredient: Dodecamethylcyclohexasiloxane 80.0ml
Solvent: Ethanol 40.0ml
Propellant: LPG 30.0ml
Propellant: Isopentane 30.0ml

Formulation Example 2
Solid insect repellent:
A 125 mm × 65 mm mm pulp filter paper was impregnated with 500 mg of decamethylcyclopentasiloxane. This was housed in a plastic case having air permeability to prepare a solid insect repellent for clothing pests.

Formulation Example 3
Spray:
A spray having the following formulation was placed in a commercially available 150 ml trigger container to prepare a spray.
Active ingredient: 20 g dodecamethylcyclohexasiloxane
Solvent: Ethanol 80g

Formulation Example 4
Fumigant:
10 g of methylpolysiloxane, 55 g of azodicarbonamide and 35 g of talc were kneaded, granulated and dried to prepare a fumigant.

Formulation Example 5
Heating transpiration agent:
A 3 cm × 3 cm pulp mat was impregnated with 100 mg of methylpolysiloxane to obtain a heat transpiration agent. This thing evaporates an active ingredient by making it contact with a heater.

Formulation Example 6
Blowing transpiration agent 50 g of dodecamethylcyclohexasiloxane was impregnated into 50 g of a pulp impregnated product (average particle size 5 mm) to obtain a blasting transpiration agent. This product evaporates the active ingredient with a fan type insect repellent.

  The silicone compound which is an active ingredient of the insect repellent of the present invention exhibits an excellent insect repellent effect against pests and insect eggs, and is safe to the human body and has high stability. . Therefore, the insect repellent of the present invention can be easily used in general households.

Further, by using the insect repellent of the present invention in an insect repellent that can be effectively released into the environment, a high insect repellent effect can be obtained, and it is widely used for insect repellent applications.
more than

Claims (18)

  An insect repellent comprising a silicone compound as an active ingredient.   The insect repellent according to claim 1, wherein the silicone compound is volatile. The insect repellent according to claim 1 or 2, wherein the silicone compound is represented by the formula (1).

[Wherein R ₁ , R ₂ and R ₃ may be different from each other, a hydrogen atom, a phenyl group or formula (2)

-XR '(2)
(In the formula, X represents an alkylene group having 1 to 10 carbon atoms or an oxygen atom, and R ′ represents a hydrogen atom, phenyl group, epoxy group, amino group, carboxyl group, hydroxyl group, trifluoromethyl group, trimethylsilyl group, — ( OC ₂ H ₄ ) _a- (OC ₃ H ₆ ) _b OR ″ (a and b are natural numbers of 0 to 10 which may be different, and R ″ is an alkyl group having 1 to 10 carbon atoms) Or —NH— (CH ₂ ) _c —NH ₂ (where c is a natural number of 1 to 10), and m, n, and o are 0 to 100, which may be different.] The insect repellent according to claim 1 or 2, wherein the silicone compound is represented by the formula (3).

[Wherein, Y and Z each represent an optionally substituted alkylene group having 1 to 10 carbon atoms, a phenylene group or a single bond, R ₄ represents a methyl group or a hydroxyl group, and R ₅ represents a methyl group or — (CH ₂ ) _D -NH- (CH ₂ ) _e -NH ₂ (d and e are natural numbers of 1 to 10 which may be different), and p and q represent natural numbers of 0 to 100 which may be different. ] The insect repellent according to claim 1 or 2, wherein the silicone compound is represented by the formula (4).

(Wherein R ₆ represents a methyl group or a phenyl group, R ₇ represents a methyl group, a phenyl group or a vinyl group, and r represents a natural number of 3 to 20)   The insect repellent according to any one of claims 1 to 5, wherein the silicone compound is used after being released into the environment.   6. The insect repellent according to any one of claims 1 to 5, wherein the silicone compound is used in contact with a pest or a pest egg in a liquid or solid state.   The insect repellent according to any one of claims 1 to 7, which is used for a pest egg.   The insect repellent according to any one of claims 1 to 7, which is used against pest larvae.   The insect repellent according to any one of claims 1 to 7, which is used against adult insects.   The insect repellent according to any one of claims 1 to 7, which is used for the purpose of inhibiting hatching of pests or killing young larvae.   The insect repellent according to any one of claims 1 to 11, wherein only the silicone compound is an active ingredient.   Furthermore, the insect repellent of Claim 1 thru | or 11 containing a plant extract.   Furthermore, the insect repellent of Claim 7 thru | or 11 containing a pyrethroid type compound.   An insect repellent having a structure in which the insect repellent according to any one of claims 1 to 14 is released into the environment by natural transpiration at room temperature, heat transpiration, air transpiration, fumigation or spraying.   A structure having a discharge port, a holding part for holding the insect repellent according to any one of claims 1 to 14 provided in the structure, a heater installed in the vicinity of the holding part, or An insect repellent comprising a blower.   An insect repellent method comprising applying the insect repellent according to any one of claims 1 to 14 to a pest or a pest egg. An insect repellent method comprising bringing a fiber product containing the insect repellent according to any one of claims 1 to 14 into contact with a pest or a pest egg.