JP2005533110A - 非抗菌性テトラサイクリン製剤によるｃ−反応性タンパク質レベルの減少方法 - Google Patents
非抗菌性テトラサイクリン製剤によるｃ−反応性タンパク質レベルの減少方法 Download PDFInfo
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- JP2005533110A JP2005533110A JP2004521686A JP2004521686A JP2005533110A JP 2005533110 A JP2005533110 A JP 2005533110A JP 2004521686 A JP2004521686 A JP 2004521686A JP 2004521686 A JP2004521686 A JP 2004521686A JP 2005533110 A JP2005533110 A JP 2005533110A
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- hydrogen
- tetracycline
- cmt
- antibacterial
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- HALQELOKLVRWRI-VDBOFHIQSA-N doxycycline hyclate Chemical compound O.[Cl-].[Cl-].CCO.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H]([NH+](C)C)[C@@H]1[C@H]2O.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H]([NH+](C)C)[C@@H]1[C@H]2O HALQELOKLVRWRI-VDBOFHIQSA-N 0.000 description 1
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- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical class I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 229940071870 hydroiodic acid Drugs 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
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- 229910052749 magnesium Inorganic materials 0.000 description 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Substances [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
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- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
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- 239000007929 subcutaneous injection Substances 0.000 description 1
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- 235000000346 sugar Nutrition 0.000 description 1
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- 235000002906 tartaric acid Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39546602P | 2002-07-12 | 2002-07-12 | |
| PCT/US2003/021740 WO2004006938A1 (en) | 2002-07-12 | 2003-07-11 | Method for reducing c-rective protein levels with non-antibacterial tetracycline formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005533110A true JP2005533110A (ja) | 2005-11-04 |
| JP2005533110A5 JP2005533110A5 (https=) | 2006-10-12 |
Family
ID=30115878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004521686A Abandoned JP2005533110A (ja) | 2002-07-12 | 2003-07-11 | 非抗菌性テトラサイクリン製剤によるｃ−反応性タンパク質レベルの減少方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050282786A1 (https=) |
| EP (1) | EP1531830A4 (https=) |
| JP (1) | JP2005533110A (https=) |
| KR (1) | KR20050034713A (https=) |
| AU (1) | AU2003256496A1 (https=) |
| CA (1) | CA2491655A1 (https=) |
| NZ (1) | NZ538198A (https=) |
| WO (1) | WO2004006938A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004091483A2 (en) * | 2003-04-07 | 2004-10-28 | Shire Laboratories, Inc. | Once daily formulations of tetracyclines |
| CN104957154B (zh) * | 2015-06-24 | 2018-05-18 | 广东中迅农科股份有限公司 | 含有四霉素和醚菌酯的杀菌组合物 |
| CN105010359B (zh) * | 2015-06-24 | 2018-05-18 | 广东中迅农科股份有限公司 | 含有四霉素和氟环唑的杀菌组合物 |
| MY203238A (en) | 2018-10-29 | 2024-06-19 | Fraunhofer Ges Zur Frderung Der Angewandten Forschung E V | Tetracycline complexes with sustained activity |
| EP3982956B1 (en) * | 2019-06-14 | 2024-06-12 | Joshua O. Atiba | Triple pharmaceutical composition for proteinaceous infection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666897A (en) * | 1983-12-29 | 1987-05-19 | Research Foundation Of State University | Inhibition of mammalian collagenolytic enzymes by tetracyclines |
| US5223248A (en) * | 1991-02-11 | 1993-06-29 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing antiplaque properties |
| US5523297A (en) * | 1993-03-02 | 1996-06-04 | The Research Foundation Of State University Of New York | Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines |
| US5827840A (en) * | 1996-08-01 | 1998-10-27 | The Research Foundation Of State University Of New York | Promotion of wound healing by chemically-modified tetracyclines |
| US5789395A (en) * | 1996-08-30 | 1998-08-04 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds for inhibition of endogenous nitric oxide production |
| EP2327409A1 (en) * | 2001-07-13 | 2011-06-01 | Paratek Pharmaceuticals, Inc. | Tetracycline compound having target therapeutic activities |
-
2003
- 2003-07-11 CA CA002491655A patent/CA2491655A1/en not_active Abandoned
- 2003-07-11 WO PCT/US2003/021740 patent/WO2004006938A1/en not_active Ceased
- 2003-07-11 JP JP2004521686A patent/JP2005533110A/ja not_active Abandoned
- 2003-07-11 KR KR1020057000506A patent/KR20050034713A/ko not_active Withdrawn
- 2003-07-11 AU AU2003256496A patent/AU2003256496A1/en not_active Abandoned
- 2003-07-11 NZ NZ538198A patent/NZ538198A/en unknown
- 2003-07-11 US US10/519,534 patent/US20050282786A1/en not_active Abandoned
- 2003-07-11 EP EP03764515A patent/EP1531830A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1531830A4 (en) | 2007-09-05 |
| CA2491655A1 (en) | 2004-01-22 |
| WO2004006938A1 (en) | 2004-01-22 |
| KR20050034713A (ko) | 2005-04-14 |
| AU2003256496A1 (en) | 2004-02-02 |
| US20050282786A1 (en) | 2005-12-22 |
| EP1531830A1 (en) | 2005-05-25 |
| NZ538198A (en) | 2006-11-30 |
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| A762 | Written abandonment of application |
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