JP2005529585A5 - - Google Patents
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- Publication number
- JP2005529585A5 JP2005529585A5 JP2003564196A JP2003564196A JP2005529585A5 JP 2005529585 A5 JP2005529585 A5 JP 2005529585A5 JP 2003564196 A JP2003564196 A JP 2003564196A JP 2003564196 A JP2003564196 A JP 2003564196A JP 2005529585 A5 JP2005529585 A5 JP 2005529585A5
- Authority
- JP
- Japan
- Prior art keywords
- snp
- 1rnic
- alleles
- 1rnsec
- detecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 101001002634 Homo sapiens Interleukin-1 alpha Proteins 0.000 claims 106
- 102100020881 Interleukin-1 alpha Human genes 0.000 claims 106
- 102100026018 Interleukin-1 receptor antagonist protein Human genes 0.000 claims 99
- 101710144554 Interleukin-1 receptor antagonist protein Proteins 0.000 claims 99
- 101001033249 Homo sapiens Interleukin-1 beta Proteins 0.000 claims 97
- 102100039065 Interleukin-1 beta Human genes 0.000 claims 97
- 102100021150 Interleukin-36 receptor antagonist protein Human genes 0.000 claims 83
- 101710089409 Interleukin-36 receptor antagonist protein Proteins 0.000 claims 83
- 238000000034 method Methods 0.000 claims 31
- 102000000589 Interleukin-1 Human genes 0.000 claims 27
- 108010002352 Interleukin-1 Proteins 0.000 claims 27
- 108700028369 Alleles Proteins 0.000 claims 20
- 102000054766 genetic haplotypes Human genes 0.000 claims 13
- 102000040430 polynucleotide Human genes 0.000 claims 9
- 108091033319 polynucleotide Proteins 0.000 claims 9
- 239000002157 polynucleotide Substances 0.000 claims 9
- 102100033474 Interleukin-36 alpha Human genes 0.000 claims 8
- 108050004801 Interleukin-36 alpha Proteins 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 8
- 229940124597 therapeutic agent Drugs 0.000 claims 8
- 230000002757 inflammatory effect Effects 0.000 claims 7
- 101150009243 HAP1 gene Proteins 0.000 claims 4
- 101000998122 Homo sapiens Interleukin-37 Proteins 0.000 claims 4
- 102100033498 Interleukin-36 beta Human genes 0.000 claims 4
- 108050003379 Interleukin-36 beta Proteins 0.000 claims 4
- 102100033502 Interleukin-37 Human genes 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 238000003205 genotyping method Methods 0.000 claims 2
- 101710148027 Ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic Proteins 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 102000014909 interleukin-1 receptor activity proteins Human genes 0.000 claims 1
- 108040006732 interleukin-1 receptor activity proteins Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35195102P | 2002-01-25 | 2002-01-25 | |
| PCT/US2003/002232 WO2003064600A2 (en) | 2002-01-25 | 2003-01-27 | The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005529585A JP2005529585A (ja) | 2005-10-06 |
| JP2005529585A5 true JP2005529585A5 (https=) | 2006-01-05 |
Family
ID=27663040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003564196A Pending JP2005529585A (ja) | 2002-01-25 | 2003-01-27 | Il−1遺伝子群ならびに関連する炎症性多型およびハプロタイプ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040171038A1 (https=) |
| EP (1) | EP1572899A4 (https=) |
| JP (1) | JP2005529585A (https=) |
| KR (1) | KR100924468B1 (https=) |
| CN (1) | CN1751127A (https=) |
| CA (1) | CA2473641A1 (https=) |
| TW (1) | TWI346700B (https=) |
| WO (1) | WO2003064600A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070264645A1 (en) * | 2002-01-25 | 2007-11-15 | Kenneth Kornman | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| US7584058B2 (en) * | 2003-02-27 | 2009-09-01 | Methexis Genomics N.V. | Genetic diagnosis using multiple sequence variant analysis |
| US8105775B2 (en) | 2005-10-25 | 2012-01-31 | Interleukin Genetics, Inc. | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| CN101389769A (zh) * | 2005-12-28 | 2009-03-18 | 森托科尔公司 | 用于评价和治疗银屑病及相关疾病的标记与方法 |
| EP2089538B1 (en) * | 2006-11-15 | 2013-08-21 | Interleukin Genetics, Inc. | The il-1 gene cluster and insulin resistance: associated polymorphisms, haplotypes and methods of using same |
| JP5762282B2 (ja) * | 2008-05-02 | 2015-08-12 | インタールーキン ジェネティクス, インコーポレイテッド | 変形性関節症に関連する状態に対する遺伝的素因の検出 |
| KR101610861B1 (ko) | 2014-07-28 | 2016-04-11 | (주)케어젠 | 골분화 촉진능 및 치주인대섬유모세포 활성 촉진능을 갖는 펩타이드 및 이의 용도 |
| WO2017040695A1 (en) * | 2015-09-01 | 2017-03-09 | Recombinetics, Inc. | Method of identifying the presence of foreign alleles in a desired haplotype |
| CN114250279B (zh) * | 2020-09-22 | 2024-04-30 | 上海韦翰斯生物医药科技有限公司 | 一种单倍型的构建方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9621129D0 (en) * | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6524795B1 (en) * | 1997-03-10 | 2003-02-25 | Interleukin Genetics, Inc. | Diagnostics for cardiovascular disorders |
| US7820383B2 (en) * | 1997-03-10 | 2010-10-26 | Interleukin Genetics, Inc. | Method for diagnosing myocardial infarction |
| US6210877B1 (en) * | 1997-03-10 | 2001-04-03 | Interleukin Genetics, Inc. | Prediction of coronary artery disease |
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| US6733967B1 (en) * | 1998-04-21 | 2004-05-11 | Interleukin Genetics, Inc. | Fetal testing for prediction of low birth weight |
| MXPA02002251A (es) * | 1999-08-30 | 2003-08-20 | Interleukin Genetics Inc | Diagnosticos y terapeuticos para osteoporosis. |
-
2003
- 2003-01-27 WO PCT/US2003/002232 patent/WO2003064600A2/en not_active Ceased
- 2003-01-27 JP JP2003564196A patent/JP2005529585A/ja active Pending
- 2003-01-27 TW TW092101760A patent/TWI346700B/zh not_active IP Right Cessation
- 2003-01-27 KR KR1020047011470A patent/KR100924468B1/ko not_active Expired - Fee Related
- 2003-01-27 CA CA002473641A patent/CA2473641A1/en not_active Abandoned
- 2003-01-27 CN CN03806113.9A patent/CN1751127A/zh active Pending
- 2003-01-27 EP EP03704010A patent/EP1572899A4/en not_active Withdrawn
- 2003-11-17 US US10/716,029 patent/US20040171038A1/en not_active Abandoned
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