JP2005523687A5 - - Google Patents
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- Publication number
- JP2005523687A5 JP2005523687A5 JP2003557507A JP2003557507A JP2005523687A5 JP 2005523687 A5 JP2005523687 A5 JP 2005523687A5 JP 2003557507 A JP2003557507 A JP 2003557507A JP 2003557507 A JP2003557507 A JP 2003557507A JP 2005523687 A5 JP2005523687 A5 JP 2005523687A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- tm7xn1
- moiety
- compound
- astrocytoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 29
- 206010028980 Neoplasm Diseases 0.000 claims 12
- 102100031934 Adhesion G-protein coupled receptor G1 Human genes 0.000 claims 9
- 101000775042 Homo sapiens Adhesion G-protein coupled receptor G1 Proteins 0.000 claims 9
- 208000003174 Brain Neoplasms Diseases 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 7
- 206010003571 Astrocytoma Diseases 0.000 claims 6
- 238000003384 imaging method Methods 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 4
- 206010038389 Renal cancer Diseases 0.000 claims 4
- 239000013543 active substance Substances 0.000 claims 4
- 208000009956 adenocarcinoma Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 201000010982 kidney cancer Diseases 0.000 claims 4
- 201000001441 melanoma Diseases 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 208000005017 glioblastoma Diseases 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 231100000433 cytotoxic Toxicity 0.000 claims 2
- 230000001472 cytotoxic effect Effects 0.000 claims 2
- 238000007913 intrathecal administration Methods 0.000 claims 2
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 108700020796 Oncogene Proteins 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 231100000196 chemotoxic Toxicity 0.000 claims 1
- 230000002604 chemotoxic effect Effects 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 230000003828 downregulation Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 108700012359 toxins Proteins 0.000 claims 1
- 238000011820 transgenic animal model Methods 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 230000003827 upregulation Effects 0.000 claims 1
- 239000012905 visible particle Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34342201P | 2001-12-27 | 2001-12-27 | |
| PCT/US2002/041419 WO2003057148A2 (en) | 2001-12-27 | 2002-12-23 | Use of biomolecular targets in the treatment and visualization of tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005523687A JP2005523687A (ja) | 2005-08-11 |
| JP2005523687A5 true JP2005523687A5 (https=) | 2005-12-22 |
Family
ID=23346050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003557507A Pending JP2005523687A (ja) | 2001-12-27 | 2002-12-23 | 腫瘍の処置及び可視化における生体分子標的の使用法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7368098B2 (https=) |
| EP (1) | EP1465997A4 (https=) |
| JP (1) | JP2005523687A (https=) |
| AU (1) | AU2002360773A1 (https=) |
| CA (1) | CA2469480A1 (https=) |
| WO (1) | WO2003057148A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005073621A (ja) * | 2003-09-01 | 2005-03-24 | Japan Science & Technology Agency | 脳腫瘍マーカーと脳腫瘍の診断方法 |
| US20050255045A1 (en) * | 2004-05-13 | 2005-11-17 | Woltering Eugene A | Surgical marking composition and method |
| EP2290071B1 (en) | 2004-05-28 | 2014-12-31 | Asuragen, Inc. | Methods and compositions involving microRNA |
| WO2006020557A2 (en) * | 2004-08-10 | 2006-02-23 | Immusol, Inc. | Methods of using or identifying agents that inhibit cancer growth |
| CA2857881A1 (en) | 2004-11-12 | 2006-12-28 | Asuragen, Inc. | Methods and compositions involving mirna and mirna inhibitor molecules |
| EP1815864A4 (en) * | 2004-11-15 | 2009-08-05 | Kyowa Hakko Kirin Co Ltd | METHOD FOR THE SUPPRESSION OF METASTASIS OF CANCER CELLS AND MEDICAL COMPOSITION THEREFOR |
| US9603941B2 (en) * | 2006-01-24 | 2017-03-28 | Minghui Chai | Method of preparing dendritic drugs |
| WO2008036765A2 (en) * | 2006-09-19 | 2008-03-27 | Asuragen, Inc. | Micrornas differentially expressed in pancreatic diseases and uses thereof |
| JP2010510964A (ja) * | 2006-09-19 | 2010-04-08 | アシュラジェン インコーポレイテッド | 治療的介入の標的としての、ｍｉＲ−１５、ｍｉＲ−２６、ｍｉＲ−３１、ｍｉＲ−１４５、ｍｉＲ−１４７、ｍｉＲ−１８８、ｍｉＲ−２１５、ｍｉＲ−２１６、ｍｉＲ−３３１、ｍｍｕ−ｍｉＲ−２９２−３ｐによって調節される遺伝子および経路 |
| DK2104737T3 (da) * | 2006-12-08 | 2013-05-27 | Asuragen Inc | Funktioner og formål for let-7 mikro-RNAer |
| WO2008073915A2 (en) * | 2006-12-08 | 2008-06-19 | Asuragen, Inc. | Micrornas differentially expressed in leukemia and uses thereof |
| WO2008073920A2 (en) * | 2006-12-08 | 2008-06-19 | Asuragen, Inc. | Mir-21 regulated genes and pathways as targets for therapeutic intervention |
| CA2671270A1 (en) * | 2006-12-29 | 2008-07-17 | Asuragen, Inc. | Mir-16 regulated genes and pathways as targets for therapeutic intervention |
| US20090232893A1 (en) * | 2007-05-22 | 2009-09-17 | Bader Andreas G | miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
| US20090131354A1 (en) * | 2007-05-22 | 2009-05-21 | Bader Andreas G | miR-126 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
| JP2010529966A (ja) * | 2007-06-08 | 2010-09-02 | アシュラジェン インコーポレイテッド | 治療的介入の標的としてｍｉＲ−３４によって調節される遺伝子および経路 |
| US8361714B2 (en) | 2007-09-14 | 2013-01-29 | Asuragen, Inc. | Micrornas differentially expressed in cervical cancer and uses thereof |
| US20090186015A1 (en) * | 2007-10-18 | 2009-07-23 | Latham Gary J | Micrornas differentially expressed in lung diseases and uses thereof |
| US8071562B2 (en) * | 2007-12-01 | 2011-12-06 | Mirna Therapeutics, Inc. | MiR-124 regulated genes and pathways as targets for therapeutic intervention |
| WO2009086156A2 (en) * | 2007-12-21 | 2009-07-09 | Asuragen, Inc. | Mir-10 regulated genes and pathways as targets for therapeutic intervention |
| US20090263803A1 (en) * | 2008-02-08 | 2009-10-22 | Sylvie Beaudenon | Mirnas differentially expressed in lymph nodes from cancer patients |
| EP2268832A2 (en) * | 2008-03-06 | 2011-01-05 | Asuragen, INC. | Microrna markers for recurrence of colorectal cancer |
| EP2271757A2 (en) * | 2008-03-26 | 2011-01-12 | Asuragen, INC. | Compositions and methods related to mir-16 and therapy of prostate cancer |
| US8258111B2 (en) | 2008-05-08 | 2012-09-04 | The Johns Hopkins University | Compositions and methods related to miRNA modulation of neovascularization or angiogenesis |
| CA2738124A1 (en) * | 2008-09-22 | 2010-03-25 | Nihon Medi-Physics Co., Ltd. | Device for creating database of alternative normal brain |
| US20100074480A1 (en) * | 2008-09-22 | 2010-03-25 | University Of Washington | Device for generating alternative of normal brain database |
| US20100179213A1 (en) * | 2008-11-11 | 2010-07-15 | Mirna Therapeutics, Inc. | Methods and Compositions Involving miRNAs In Cancer Stem Cells |
| CN103459598B (zh) | 2011-02-03 | 2016-08-10 | 米尔纳医疗股份有限公司 | Mir-124的合成模拟物 |
| WO2013040251A2 (en) | 2011-09-13 | 2013-03-21 | Asurgen, Inc. | Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease |
| WO2015143074A1 (en) * | 2014-03-20 | 2015-09-24 | University Of Southern California | Brain cancer immunotherapy |
| US12358959B2 (en) | 2016-03-31 | 2025-07-15 | Children's Medical Center Corporation | Compositions and methods for oligodendrocyte development |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030167485A1 (en) * | 1997-09-24 | 2003-09-04 | Garvan Institute Of Medical Research | Novel G protein-coupled receptor encoding gene and diagnostic uses therefor |
| US6391311B1 (en) * | 1998-03-17 | 2002-05-21 | Genentech, Inc. | Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1 |
| WO2000020590A2 (en) | 1998-10-06 | 2000-04-13 | Incyte Pharmaceuticals, Inc. | G-protein coupled receptor proteins |
| EP1033404A1 (en) * | 1999-01-29 | 2000-09-06 | F. Hoffmann-La Roche Ag | New gene with down-regulated expression in metastatic human melanoma cells |
-
2002
- 2002-12-23 US US10/328,544 patent/US7368098B2/en not_active Expired - Lifetime
- 2002-12-23 WO PCT/US2002/041419 patent/WO2003057148A2/en not_active Ceased
- 2002-12-23 AU AU2002360773A patent/AU2002360773A1/en not_active Abandoned
- 2002-12-23 EP EP02796055A patent/EP1465997A4/en not_active Withdrawn
- 2002-12-23 US US10/329,258 patent/US7014838B2/en not_active Expired - Lifetime
- 2002-12-23 CA CA002469480A patent/CA2469480A1/en not_active Abandoned
- 2002-12-23 JP JP2003557507A patent/JP2005523687A/ja active Pending
-
2008
- 2008-03-10 US US12/045,448 patent/US20080226646A1/en not_active Abandoned
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