JP2005523687A - 腫瘍の処置及び可視化における生体分子標的の使用法 - Google Patents

腫瘍の処置及び可視化における生体分子標的の使用法 Download PDF

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JP2005523687A
JP2005523687A JP2003557507A JP2003557507A JP2005523687A JP 2005523687 A JP2005523687 A JP 2005523687A JP 2003557507 A JP2003557507 A JP 2003557507A JP 2003557507 A JP2003557507 A JP 2003557507A JP 2005523687 A JP2005523687 A JP 2005523687A
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moiety
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tumor
polypeptide
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ミレラ ゴンザレス−ズルエタ
サビン ムエラー
エリック フォアー
ダニエル チン
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エージーワイ セラピューティクス インコーポレイティッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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JP2003557507A 2001-12-27 2002-12-23 腫瘍の処置及び可視化における生体分子標的の使用法 Pending JP2005523687A (ja)

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Application Number Priority Date Filing Date Title
US34342201P 2001-12-27 2001-12-27
PCT/US2002/041419 WO2003057148A2 (en) 2001-12-27 2002-12-23 Use of biomolecular targets in the treatment and visualization of tumors

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JP2005523687A true JP2005523687A (ja) 2005-08-11
JP2005523687A5 JP2005523687A5 (https=) 2005-12-22

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US (3) US7368098B2 (https=)
EP (1) EP1465997A4 (https=)
JP (1) JP2005523687A (https=)
AU (1) AU2002360773A1 (https=)
CA (1) CA2469480A1 (https=)
WO (1) WO2003057148A2 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005073621A (ja) * 2003-09-01 2005-03-24 Japan Science & Technology Agency 脳腫瘍マーカーと脳腫瘍の診断方法
US20050255045A1 (en) * 2004-05-13 2005-11-17 Woltering Eugene A Surgical marking composition and method
EP2290071B1 (en) 2004-05-28 2014-12-31 Asuragen, Inc. Methods and compositions involving microRNA
WO2006020557A2 (en) * 2004-08-10 2006-02-23 Immusol, Inc. Methods of using or identifying agents that inhibit cancer growth
CA2857881A1 (en) 2004-11-12 2006-12-28 Asuragen, Inc. Methods and compositions involving mirna and mirna inhibitor molecules
EP1815864A4 (en) * 2004-11-15 2009-08-05 Kyowa Hakko Kirin Co Ltd METHOD FOR THE SUPPRESSION OF METASTASIS OF CANCER CELLS AND MEDICAL COMPOSITION THEREFOR
US9603941B2 (en) * 2006-01-24 2017-03-28 Minghui Chai Method of preparing dendritic drugs
WO2008036765A2 (en) * 2006-09-19 2008-03-27 Asuragen, Inc. Micrornas differentially expressed in pancreatic diseases and uses thereof
JP2010510964A (ja) * 2006-09-19 2010-04-08 アシュラジェン インコーポレイテッド 治療的介入の標的としての、miR−15、miR−26、miR−31、miR−145、miR−147、miR−188、miR−215、miR−216、miR−331、mmu−miR−292−3pによって調節される遺伝子および経路
DK2104737T3 (da) * 2006-12-08 2013-05-27 Asuragen Inc Funktioner og formål for let-7 mikro-RNAer
WO2008073915A2 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. Micrornas differentially expressed in leukemia and uses thereof
WO2008073920A2 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. Mir-21 regulated genes and pathways as targets for therapeutic intervention
CA2671270A1 (en) * 2006-12-29 2008-07-17 Asuragen, Inc. Mir-16 regulated genes and pathways as targets for therapeutic intervention
US20090232893A1 (en) * 2007-05-22 2009-09-17 Bader Andreas G miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
US20090131354A1 (en) * 2007-05-22 2009-05-21 Bader Andreas G miR-126 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
JP2010529966A (ja) * 2007-06-08 2010-09-02 アシュラジェン インコーポレイテッド 治療的介入の標的としてmiR−34によって調節される遺伝子および経路
US8361714B2 (en) 2007-09-14 2013-01-29 Asuragen, Inc. Micrornas differentially expressed in cervical cancer and uses thereof
US20090186015A1 (en) * 2007-10-18 2009-07-23 Latham Gary J Micrornas differentially expressed in lung diseases and uses thereof
US8071562B2 (en) * 2007-12-01 2011-12-06 Mirna Therapeutics, Inc. MiR-124 regulated genes and pathways as targets for therapeutic intervention
WO2009086156A2 (en) * 2007-12-21 2009-07-09 Asuragen, Inc. Mir-10 regulated genes and pathways as targets for therapeutic intervention
US20090263803A1 (en) * 2008-02-08 2009-10-22 Sylvie Beaudenon Mirnas differentially expressed in lymph nodes from cancer patients
EP2268832A2 (en) * 2008-03-06 2011-01-05 Asuragen, INC. Microrna markers for recurrence of colorectal cancer
EP2271757A2 (en) * 2008-03-26 2011-01-12 Asuragen, INC. Compositions and methods related to mir-16 and therapy of prostate cancer
US8258111B2 (en) 2008-05-08 2012-09-04 The Johns Hopkins University Compositions and methods related to miRNA modulation of neovascularization or angiogenesis
CA2738124A1 (en) * 2008-09-22 2010-03-25 Nihon Medi-Physics Co., Ltd. Device for creating database of alternative normal brain
US20100074480A1 (en) * 2008-09-22 2010-03-25 University Of Washington Device for generating alternative of normal brain database
US20100179213A1 (en) * 2008-11-11 2010-07-15 Mirna Therapeutics, Inc. Methods and Compositions Involving miRNAs In Cancer Stem Cells
CN103459598B (zh) 2011-02-03 2016-08-10 米尔纳医疗股份有限公司 Mir-124的合成模拟物
WO2013040251A2 (en) 2011-09-13 2013-03-21 Asurgen, Inc. Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease
WO2015143074A1 (en) * 2014-03-20 2015-09-24 University Of Southern California Brain cancer immunotherapy
US12358959B2 (en) 2016-03-31 2025-07-15 Children's Medical Center Corporation Compositions and methods for oligodendrocyte development

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030167485A1 (en) * 1997-09-24 2003-09-04 Garvan Institute Of Medical Research Novel G protein-coupled receptor encoding gene and diagnostic uses therefor
US6391311B1 (en) * 1998-03-17 2002-05-21 Genentech, Inc. Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1
WO2000020590A2 (en) 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. G-protein coupled receptor proteins
EP1033404A1 (en) * 1999-01-29 2000-09-06 F. Hoffmann-La Roche Ag New gene with down-regulated expression in metastatic human melanoma cells

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CA2469480A1 (en) 2003-07-17
EP1465997A2 (en) 2004-10-13
US7368098B2 (en) 2008-05-06
EP1465997A4 (en) 2006-05-24
WO2003057148A2 (en) 2003-07-17
WO2003057148A3 (en) 2004-01-15
US7014838B2 (en) 2006-03-21
US20030175209A1 (en) 2003-09-18
US20080226646A1 (en) 2008-09-18
AU2002360773A1 (en) 2003-07-24

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