JP2005519918A - 病因性状態を予防または治療するためのアルドステロン受容体拮抗剤およびα−アドレナリン作用変調剤の組み合わせ治療 - Google Patents
病因性状態を予防または治療するためのアルドステロン受容体拮抗剤およびα−アドレナリン作用変調剤の組み合わせ治療 Download PDFInfo
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- JP2005519918A JP2005519918A JP2003563540A JP2003563540A JP2005519918A JP 2005519918 A JP2005519918 A JP 2005519918A JP 2003563540 A JP2003563540 A JP 2003563540A JP 2003563540 A JP2003563540 A JP 2003563540A JP 2005519918 A JP2005519918 A JP 2005519918A
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- receptor antagonist
- aldosterone receptor
- adrenergic
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
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- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Engineering & Computer Science (AREA)
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- Organic Chemistry (AREA)
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- Hematology (AREA)
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- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35380102P | 2002-01-30 | 2002-01-30 | |
| PCT/US2003/002723 WO2003063846A2 (en) | 2002-01-30 | 2003-01-30 | Aldosterone receptor antagonist and alpha-adrenergic modulating agent combination therapy for prevention or treatment of cardiovascular conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005519918A true JP2005519918A (ja) | 2005-07-07 |
| JP2005519918A5 JP2005519918A5 (enExample) | 2006-03-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003563540A Abandoned JP2005519918A (ja) | 2002-01-30 | 2003-01-30 | 病因性状態を予防または治療するためのアルドステロン受容体拮抗剤およびα−アドレナリン作用変調剤の組み合わせ治療 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20030199483A1 (enExample) |
| EP (1) | EP1469862A2 (enExample) |
| JP (1) | JP2005519918A (enExample) |
| KR (1) | KR20040096540A (enExample) |
| CN (1) | CN1625404A (enExample) |
| BR (1) | BR0307336A (enExample) |
| CA (1) | CA2474845A1 (enExample) |
| MX (1) | MXPA04007472A (enExample) |
| PL (1) | PL371437A1 (enExample) |
| WO (1) | WO2003063846A2 (enExample) |
| ZA (1) | ZA200405437B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100381163C (zh) * | 2006-08-29 | 2008-04-16 | 陈俊云 | 一种含利美尼定的药物 |
| EP2727587A1 (en) * | 2012-10-30 | 2014-05-07 | Pharnext | Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level |
| WO2016141182A1 (en) | 2015-03-03 | 2016-09-09 | Yee Richard W | Compositions and methods for treating ocular diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5529992A (en) * | 1992-04-21 | 1996-06-25 | Curators Of The University Of Missouri | Method for inhibiting myocardial fibrosis by administering an aldosterone antagonist which suppresses aldoster one receptors |
| US5932538A (en) * | 1996-02-02 | 1999-08-03 | Nitromed, Inc. | Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses |
| WO2001087284A2 (en) * | 2000-05-11 | 2001-11-22 | Pharmacia Corporation | Aldosterone antagonist composition for release during aldosterone acrophase |
| US20040235809A1 (en) * | 2000-07-27 | 2004-11-25 | Alexander John C | Epoxy steroidal aldosterone antagonist and beta-adremergic antagonist combination therepy for treatment of congestive heart failure |
| WO2003049745A1 (en) * | 2001-12-12 | 2003-06-19 | Pharmacia Corporation | Method of treating ophthalmic disorders with epoxy-steroidal aldosterone receptor antagonists |
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2003
- 2003-01-30 EP EP20030710786 patent/EP1469862A2/en not_active Withdrawn
- 2003-01-30 KR KR10-2004-7011714A patent/KR20040096540A/ko not_active Ceased
- 2003-01-30 MX MXPA04007472A patent/MXPA04007472A/es unknown
- 2003-01-30 BR BR0307336-0A patent/BR0307336A/pt not_active IP Right Cessation
- 2003-01-30 PL PL03371437A patent/PL371437A1/xx not_active Application Discontinuation
- 2003-01-30 US US10/354,653 patent/US20030199483A1/en not_active Abandoned
- 2003-01-30 CN CNA03802988XA patent/CN1625404A/zh active Pending
- 2003-01-30 WO PCT/US2003/002723 patent/WO2003063846A2/en not_active Ceased
- 2003-01-30 CA CA002474845A patent/CA2474845A1/en not_active Abandoned
- 2003-01-30 JP JP2003563540A patent/JP2005519918A/ja not_active Abandoned
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2004
- 2004-07-08 ZA ZA200405437A patent/ZA200405437B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20030199483A1 (en) | 2003-10-23 |
| CA2474845A1 (en) | 2003-08-07 |
| MXPA04007472A (es) | 2004-11-10 |
| WO2003063846A3 (en) | 2003-12-04 |
| BR0307336A (pt) | 2004-12-07 |
| PL371437A1 (en) | 2005-06-13 |
| EP1469862A2 (en) | 2004-10-27 |
| ZA200405437B (en) | 2005-07-08 |
| WO2003063846A2 (en) | 2003-08-07 |
| KR20040096540A (ko) | 2004-11-16 |
| CN1625404A (zh) | 2005-06-08 |
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