JP2005519877A - Hiv感染のための幹細胞スクリーニングおよび移植治療 - Google Patents

Hiv感染のための幹細胞スクリーニングおよび移植治療 Download PDF

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JP2005519877A
JP2005519877A JP2003546840A JP2003546840A JP2005519877A JP 2005519877 A JP2005519877 A JP 2005519877A JP 2003546840 A JP2003546840 A JP 2003546840A JP 2003546840 A JP2003546840 A JP 2003546840A JP 2005519877 A JP2005519877 A JP 2005519877A
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cells
hiv
polymorphism
gene
stem cells
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JP2005519877A5 (ja
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ロバート チャウ
デニス オー. ロッドジャーソン
ルビオ アール. プンツァラン
ローレンス ディー. ペッツ
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StemCyte Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
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  • Biotechnology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
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  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
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  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003546840A 2001-11-29 2002-11-27 Hiv感染のための幹細胞スクリーニングおよび移植治療 Withdrawn JP2005519877A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/998,832 US20030099621A1 (en) 2001-11-29 2001-11-29 Stem cell screening and transplantation therapy for HIV infection
PCT/US2002/038436 WO2003045335A2 (en) 2001-11-29 2002-11-27 Stem cell screening and transplantation therapy for hiv infection

Related Child Applications (1)

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JP2009284587A Division JP5675088B2 (ja) 2001-11-29 2009-12-15 Hiv感染に対する幹細胞スクリーニングおよび移植治療

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JP2005519877A true JP2005519877A (ja) 2005-07-07
JP2005519877A5 JP2005519877A5 (ja) 2010-02-12

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JP2003546840A Withdrawn JP2005519877A (ja) 2001-11-29 2002-11-27 Hiv感染のための幹細胞スクリーニングおよび移植治療
JP2009284587A Expired - Lifetime JP5675088B2 (ja) 2001-11-29 2009-12-15 Hiv感染に対する幹細胞スクリーニングおよび移植治療
JP2012215505A Expired - Fee Related JP5829993B2 (ja) 2001-11-29 2012-09-28 Hiv感染に対する幹細胞スクリーニングおよび移植治療

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JP2009284587A Expired - Lifetime JP5675088B2 (ja) 2001-11-29 2009-12-15 Hiv感染に対する幹細胞スクリーニングおよび移植治療
JP2012215505A Expired - Fee Related JP5829993B2 (ja) 2001-11-29 2012-09-28 Hiv感染に対する幹細胞スクリーニングおよび移植治療

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US (2) US20030099621A1 (enExample)
EP (1) EP1469888B1 (enExample)
JP (3) JP2005519877A (enExample)
AU (1) AU2002353006A1 (enExample)
WO (1) WO2003045335A2 (enExample)

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KR101042448B1 (ko) 2002-11-26 2011-06-16 안트로제네시스 코포레이션 세포요법제, 세포요법제 단위 및 이를 이용한 치료방법
WO2007016372A2 (en) * 2005-07-28 2007-02-08 Eden Biotech Ltd. Method for regenerating an immune system
PT3255061T (pt) * 2006-11-03 2021-07-26 Univ Leland Stanford Junior Imunodepleção seletiva de nicho de células estaminais endógenas para enxerto
PT2164993T (pt) 2007-05-29 2017-01-12 Reid Christopher B Métodos para produção e usos de populações de células multipotentes, populações de células pluripotentes, populações de célula diferenciadas e populações de células resistentes a vih
CA2840540A1 (en) * 2011-06-29 2013-01-03 Ronilu Development Corporation Prevention and treatment of hiv infection
WO2014151994A1 (en) 2013-03-15 2014-09-25 Kambiz Shekdar Genome editing using effector oligonucleotides for therapeutic treatment
RU2563172C1 (ru) * 2014-11-12 2015-09-20 Общество с ограниченной ответственностью "Покровский банк стволовых клеток" СПОСОБ ОПРЕДЕЛЕНИЯ АЛЛЕЛЬНОГО ПОЛИМОРФИЗМА CCR5 delta 32
US10426796B2 (en) * 2016-06-13 2019-10-01 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US10456423B2 (en) 2016-06-13 2019-10-29 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
CA3053129A1 (en) * 2017-02-10 2018-08-16 Abraham J And Phyllis Katz Cord Blood Foundation Methods of treating hiv infection with allogeneic ccr5 null umbilical cord blood cells
ES2954311T3 (es) * 2017-04-01 2023-11-21 Avm Biotechnology Llc Reemplazo de un preacondicionamiento citotóxico antes de una inmunoterapia celular
CA3082404A1 (en) * 2017-11-15 2019-05-23 Weird Science Llc Methods and compositions for non-myeloablative bone marrow reconstitution

Citations (5)

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JPH05502218A (ja) * 1989-09-14 1993-04-22 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 治療用組成物;hiv感染の治療方法
US6153431A (en) * 1997-05-30 2000-11-28 Fond Mondiale Rech & Prev Sida Human immunodeficiency virus co-receptor variants associated with resistance to virus infection
WO2001058916A2 (en) * 2000-02-09 2001-08-16 Human Genome Sciences, Inc. Antibodies to ccr5
JP2001514886A (ja) * 1997-08-14 2001-09-18 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ, アズ レプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ Ccr2遺伝子のミスセンス対立遺伝子によるaidsへの進行の遅延
JP2001518289A (ja) * 1997-09-29 2001-10-16 ニューロスフィアーズ ホウルディングス リミテッド 多分化能神経幹細胞からの造血細胞の生成

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US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
CA1291031C (en) 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Method for the detection of specific binding agents and their correspondingbindable substances
US6217867B1 (en) * 1993-09-13 2001-04-17 University Of Pittsburgh Non-lethal methods for conditioning a recipient for bone marrow transplantation
US20030017587A1 (en) * 2001-07-18 2003-01-23 Rader William C. Embryonic stem cells, clinical applications and methods for expanding in vitro

Patent Citations (5)

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JPH05502218A (ja) * 1989-09-14 1993-04-22 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 治療用組成物;hiv感染の治療方法
US6153431A (en) * 1997-05-30 2000-11-28 Fond Mondiale Rech & Prev Sida Human immunodeficiency virus co-receptor variants associated with resistance to virus infection
JP2001514886A (ja) * 1997-08-14 2001-09-18 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ, アズ レプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ Ccr2遺伝子のミスセンス対立遺伝子によるaidsへの進行の遅延
JP2001518289A (ja) * 1997-09-29 2001-10-16 ニューロスフィアーズ ホウルディングス リミテッド 多分化能神経幹細胞からの造血細胞の生成
WO2001058916A2 (en) * 2000-02-09 2001-08-16 Human Genome Sciences, Inc. Antibodies to ccr5

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JPN6009029321, ALIVE,S.T. et al, "Genetic restriction of AIDS pathogenesis by an SDF−1 chemokine gene variant", Science, 1998, Vol.279, No.5349, p.389−93 *
JPN6009029323, LIU,H. et al, "Polymorphism in RANTES chemokine promoter affects HIV−1 disease progression", Proc Natl Acad Sci U S A, 1999, Vol.96, No.8, p.4581−5 *
JPN6009029325, FLORES−VILLANUEVA,P.O. et al, "Control of HIV−1 viremia and protection from AIDS are associated with HLA−Bw4 homozygosity", Proc Natl Acad Sci U S A, 200104, Vol.98, No.9, p.5140−5 *
JPN6010024842, SAMSON,M. et al, "Resistance to HIV−1 infection in caucasian individuals bearing mutant alleles of the CCR−5 chemokine", Nature, 1996, Vol.382, No.6593, p.722−5 *
JPN6010024843, TAMASAUSKAS,D. et al, "A homologous naturally occurring mutation in Duffy and CCR5 leading to reduced receptor expression", Blood, 2001, Vol.97, No.11, p.3651−4 *
JPN6010024845, OMETTO,L. et al, "Polymorphisms in the CCR5 promoter region influence disease progression in perinatally human immunod", J Infect Dis, 2001, Vol.183, No.5, p.814−8 *

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Publication number Publication date
JP5675088B2 (ja) 2015-02-25
EP1469888B1 (en) 2016-06-08
EP1469888A4 (en) 2005-01-19
WO2003045335A3 (en) 2003-10-16
JP2013031450A (ja) 2013-02-14
US20050220772A1 (en) 2005-10-06
US20030099621A1 (en) 2003-05-29
JP5829993B2 (ja) 2015-12-09
AU2002353006A1 (en) 2003-06-10
JP2010116400A (ja) 2010-05-27
WO2003045335A2 (en) 2003-06-05
EP1469888A2 (en) 2004-10-27

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