JP2005519091A5 - - Google Patents
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- Publication number
- JP2005519091A5 JP2005519091A5 JP2003572444A JP2003572444A JP2005519091A5 JP 2005519091 A5 JP2005519091 A5 JP 2005519091A5 JP 2003572444 A JP2003572444 A JP 2003572444A JP 2003572444 A JP2003572444 A JP 2003572444A JP 2005519091 A5 JP2005519091 A5 JP 2005519091A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- cancer
- herpesvirus
- subject
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 claims 12
- 201000011510 cancer Diseases 0.000 claims 7
- 241001529453 unidentified herpesvirus Species 0.000 claims 7
- 238000002271 resection Methods 0.000 claims 3
- 238000011394 anticancer treatment Methods 0.000 claims 2
- 230000002238 attenuated effect Effects 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 102000053642 Catalytic RNA Human genes 0.000 claims 1
- 108090000994 Catalytic RNA Proteins 0.000 claims 1
- 241000700588 Human alphaherpesvirus 1 Species 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 238000001815 biotherapy Methods 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 231100000599 cytotoxic agent Toxicity 0.000 claims 1
- 239000002619 cytotoxin Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 230000002519 immonomodulatory effect Effects 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 210000001165 lymph node Anatomy 0.000 claims 1
- 210000004324 lymphatic system Anatomy 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 230000000174 oncolytic effect Effects 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 108091092562 ribozyme Proteins 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36113202P | 2002-03-01 | 2002-03-01 | |
| PCT/US2003/006519 WO2003073918A2 (en) | 2002-03-01 | 2003-03-03 | Prevention of recurrence and metastasis of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005519091A JP2005519091A (ja) | 2005-06-30 |
| JP2005519091A5 true JP2005519091A5 (https=) | 2006-04-20 |
Family
ID=27789076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003572444A Pending JP2005519091A (ja) | 2002-03-01 | 2003-03-03 | 癌の再発及び転移の予防 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050255085A1 (https=) |
| EP (1) | EP1487983A4 (https=) |
| JP (1) | JP2005519091A (https=) |
| AU (1) | AU2003216502B2 (https=) |
| CA (1) | CA2476724A1 (https=) |
| WO (1) | WO2003073918A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ425699A0 (en) | 1999-11-25 | 1999-12-23 | University Of Newcastle Research Associates Limited, The | A method of treating a malignancy in a subject and a pharmaceutical composition for use in same |
| AU2002953436A0 (en) | 2002-12-18 | 2003-01-09 | The University Of Newcastle Research Associates Limited | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
| GB0326798D0 (en) * | 2003-11-17 | 2003-12-24 | Crusade Lab Ltd | Methods for generating mutant virus |
| JP2005336094A (ja) * | 2004-05-26 | 2005-12-08 | Akikimi Nakao | 変異単純ヘルペスウイルスからなる転移性乳癌および再発性乳癌の治療剤 |
| CN101495126B (zh) | 2005-06-23 | 2016-01-06 | 休斯顿大学 | Ⅱ型单纯疱疹病毒突变体在治疗癌症中的用途 |
| CN106068326B (zh) | 2013-10-28 | 2021-06-18 | 联邦高等教育系统-匹兹堡大学 | 溶瘤性hsv载体 |
| PT3377637T (pt) * | 2016-04-08 | 2020-06-17 | Krystal Biotech Inc | Composições para uso em métodos para o tratamento de ferimentos, transtornos e doenças da pele |
| EP3426272A4 (en) * | 2016-04-26 | 2020-03-04 | Salk Institute for Biological Studies | ONCOLYTIC HSV-1 VIRUS THERAPIES WITH SPECIFIC KILLING OF OLD-DEPENDENT CARCINOMAS |
| AU2018306455A1 (en) | 2017-07-26 | 2020-02-27 | Virogin Biotech Canada Ltd | Oncolytic viral vectors and uses thereof |
| US11865081B2 (en) | 2017-12-29 | 2024-01-09 | Virogin Biotech Canada Ltd. | Oncolytic viral delivery of therapeutic polypeptides |
| TW202038947A (zh) | 2018-11-28 | 2020-11-01 | 德商創新分子有限責任公司 | 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑 |
| WO2020163703A1 (en) | 2019-02-08 | 2020-08-13 | Krystal Biotech, Inc. | Compositions and methods for delivering cftr polypeptides |
| BR112023020209A2 (pt) | 2021-04-02 | 2023-12-19 | Krystal Biotech Inc | Genoma do vírus do herpes recombinante, vírus do herpes, composição farmacêutica, uso do vírus do herpes ou da composição farmacêutica, método para expressar, realçar, aumentar, ampliar e/ou suplementar os níveis de um polipeptídeo imunomodulatório, método para prover alívio profilático, paliativo ou terapêutico, e, método para tratar câncer |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5162231A (en) * | 1989-10-25 | 1992-11-10 | Cole Dean A | Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung |
| US5328688A (en) * | 1990-09-10 | 1994-07-12 | Arch Development Corporation | Recombinant herpes simplex viruses vaccines and methods |
| US6770274B1 (en) * | 1990-09-14 | 2004-08-03 | The General Hospital Corporation | Viral mutant HSV mediated destruction of neoplastic cells |
| ES2183811T3 (es) * | 1992-03-31 | 2003-04-01 | Arch Dev Corp | Tratamiento de enfermedades tumorigenas con un hsv modificado. |
| US20020010144A1 (en) * | 1994-04-29 | 2002-01-24 | Robert Sobol | Enhancing the sensitivity of tumor cells to therapies |
| US6139834A (en) * | 1994-06-23 | 2000-10-31 | Georgetown University | Replication-competent Herpes simplex virus mediates destruction of neplastic cells |
| US5585096A (en) * | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
| US6403370B1 (en) * | 1997-02-10 | 2002-06-11 | Genstar Therapeutics Corporation | Oncolytic/immunogenic complementary-adenoviral vector system |
| US6379674B1 (en) * | 1997-08-12 | 2002-04-30 | Georgetown University | Use of herpes vectors for tumor therapy |
| US6406861B1 (en) * | 1998-10-07 | 2002-06-18 | Cell Genesys, Inc. | Methods of enhancing effectiveness of therapeutic viral immunogenic agent administration |
| DE60039730D1 (de) * | 1999-02-05 | 2008-09-11 | Arch Dev Corp | Genetisch manipulierte Herpesviren zur Behandlung von Tumoren |
| US6428968B1 (en) * | 1999-03-15 | 2002-08-06 | The Trustees Of The University Of Pennsylvania | Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject |
| US6764675B1 (en) * | 1999-06-08 | 2004-07-20 | The Uab Research Foundation | Herpes simplex virus expressing foreign genes and method for treating cancers therewith |
| US7064111B1 (en) * | 1999-10-05 | 2006-06-20 | Georgetown University | Use of soluble costimulatory factor for tumor immuno-gene therapy |
| EP1286678A2 (en) * | 2000-06-01 | 2003-03-05 | Sloan-Kettering Institute For Cancer Research | Combination of a mutant herpes virus and a chemotherapeutic agent for the treatment of cancer |
| CA2441663C (en) * | 2001-03-27 | 2013-01-22 | Medigene, Inc. | Viral vectors and their use in therapeutic methods |
-
2003
- 2003-03-03 AU AU2003216502A patent/AU2003216502B2/en not_active Ceased
- 2003-03-03 CA CA002476724A patent/CA2476724A1/en not_active Abandoned
- 2003-03-03 WO PCT/US2003/006519 patent/WO2003073918A2/en not_active Ceased
- 2003-03-03 EP EP03743747A patent/EP1487983A4/en not_active Withdrawn
- 2003-03-03 JP JP2003572444A patent/JP2005519091A/ja active Pending
- 2003-03-03 US US10/505,375 patent/US20050255085A1/en not_active Abandoned
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