JP2005516605A5 - - Google Patents

Info

Publication number

JP2005516605A5

JP2005516605A5 JP2003565410A JP2003565410A JP2005516605A5 JP 2005516605 A5 JP2005516605 A5 JP 2005516605A5 JP 2003565410 A JP2003565410 A JP 2003565410A JP 2003565410 A JP2003565410 A JP 2003565410A JP 2005516605 A5 JP2005516605 A5 JP 2005516605A5

Authority

JP

Japan

Prior art keywords

seq

sequence number

sequence

polypeptide

amino acid

Prior art date

2003-01-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 108090000765 processed proteins & peptides Proteins 0.000 claims 41
• 102000004196 processed proteins & peptides Human genes 0.000 claims 40
• 229920001184 polypeptide Polymers 0.000 claims 39
• 150000001875 compounds Chemical class 0.000 claims 23
• 125000003275 alpha amino acid group Chemical group 0.000 claims 17
• 239000002773 nucleotide Substances 0.000 claims 17
• 125000003729 nucleotide group Chemical group 0.000 claims 17
• 238000000034 method Methods 0.000 claims 14
• 102000039446 nucleic acids Human genes 0.000 claims 14
• 108020004707 nucleic acids Proteins 0.000 claims 14
• 150000007523 nucleic acids Chemical class 0.000 claims 14
• 208000024172 Cardiovascular disease Diseases 0.000 claims 13
• 230000000694 effects Effects 0.000 claims 11
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 10
• 210000004027 cell Anatomy 0.000 claims 7
• 230000003321 amplification Effects 0.000 claims 4
• 238000003199 nucleic acid amplification method Methods 0.000 claims 4
• 230000002792 vascular Effects 0.000 claims 4
• 239000008194 pharmaceutical composition Substances 0.000 claims 3
• 206010002383 Angina Pectoris Diseases 0.000 claims 2
• 208000036490 Arterial inflammations Diseases 0.000 claims 2
• 206010003210 Arteriosclerosis Diseases 0.000 claims 2
• 206010003225 Arteriospasm coronary Diseases 0.000 claims 2
• 201000001320 Atherosclerosis Diseases 0.000 claims 2
• 206010007572 Cardiac hypertrophy Diseases 0.000 claims 2
• 208000006029 Cardiomegaly Diseases 0.000 claims 2
• 208000003890 Coronary Vasospasm Diseases 0.000 claims 2
• 208000005189 Embolism Diseases 0.000 claims 2
• 206010020772 Hypertension Diseases 0.000 claims 2
• 206010063837 Reperfusion injury Diseases 0.000 claims 2
• 208000007536 Thrombosis Diseases 0.000 claims 2
• 208000011775 arteriosclerosis disease Diseases 0.000 claims 2
• 230000015572 biosynthetic process Effects 0.000 claims 2
• 208000029078 coronary artery disease Diseases 0.000 claims 2
• 201000011634 coronary artery vasospasm Diseases 0.000 claims 2
• 210000004351 coronary vessel Anatomy 0.000 claims 2
• 208000019622 heart disease Diseases 0.000 claims 2
• 208000023589 ischemic disease Diseases 0.000 claims 2
• 230000000302 ischemic effect Effects 0.000 claims 2
• 238000007634 remodeling Methods 0.000 claims 2
• 208000037803 restenosis Diseases 0.000 claims 2
• 150000003384 small molecules Chemical class 0.000 claims 2
• 238000007818 agglutination assay Methods 0.000 claims 1
• 238000004220 aggregation Methods 0.000 claims 1
• 230000002776 aggregation Effects 0.000 claims 1
• 230000000692 anti-sense effect Effects 0.000 claims 1
• 230000000295 complement effect Effects 0.000 claims 1
• 210000003593 megakaryocyte Anatomy 0.000 claims 1
• 102000040430 polynucleotide Human genes 0.000 claims 1
• 108091033319 polynucleotide Proteins 0.000 claims 1
• 239000002157 polynucleotide Substances 0.000 claims 1
• 210000003462 vein Anatomy 0.000 claims 1