JP2005514906A - p53経路のモディファイヤーとしてのLCEsおよび使用方法 - Google Patents
p53経路のモディファイヤーとしてのLCEsおよび使用方法 Download PDFInfo
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- JP2005514906A JP2005514906A JP2003502178A JP2003502178A JP2005514906A JP 2005514906 A JP2005514906 A JP 2005514906A JP 2003502178 A JP2003502178 A JP 2003502178A JP 2003502178 A JP2003502178 A JP 2003502178A JP 2005514906 A JP2005514906 A JP 2005514906A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4739—Cyclin; Prad 1
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2510/00—Detection of programmed cell death, i.e. apoptosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29607601P | 2001-06-05 | 2001-06-05 | |
US32860501P | 2001-10-10 | 2001-10-10 | |
US35725302P | 2002-02-15 | 2002-02-15 | |
US36119602P | 2002-03-01 | 2002-03-01 | |
PCT/US2002/017739 WO2002099068A2 (fr) | 2001-06-05 | 2002-06-03 | Lce utilises comme modificateurs de la voie p53 et procede d'utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2005514906A true JP2005514906A (ja) | 2005-05-26 |
Family
ID=27501675
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003502009A Withdrawn JP2004532638A (ja) | 2001-06-05 | 2002-06-03 | p53経路のモディファイヤーとしてのMAP3Ksおよび使用方法 |
JP2003502178A Withdrawn JP2005514906A (ja) | 2001-06-05 | 2002-06-03 | p53経路のモディファイヤーとしてのLCEsおよび使用方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003502009A Withdrawn JP2004532638A (ja) | 2001-06-05 | 2002-06-03 | p53経路のモディファイヤーとしてのMAP3Ksおよび使用方法 |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP1402051A4 (fr) |
JP (2) | JP2004532638A (fr) |
AU (1) | AU2002314887A1 (fr) |
CA (2) | CA2449479A1 (fr) |
WO (4) | WO2002099068A2 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2012233044B2 (en) * | 2002-11-22 | 2015-09-03 | Ganymed Pharmaceuticals Ag | Genetic products differentially expressed in tumors and the use thereof |
DE10254601A1 (de) * | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
EP1572118A4 (fr) * | 2002-12-20 | 2010-07-14 | Millennium Pharm Inc | Methodes et compositions de traitement de cancer au moyen des genes 15986, 2188, 20743, 9148, 9151, 9791, 44252, 14184, 42461, 8204, 7970, 25552, 21657, 26492, 2411, 15088, 1905, 28899, 63380, 33935, 10480, 12686, 25501, 17694, 15701, 53062, 49908, 21612, 38949, 6216, 46863, 9235, 2201, 6985, 9883 |
DE10316701A1 (de) * | 2003-04-09 | 2004-11-04 | Hinzmann, Bernd, Dr. | Humane Nukleinsäuresequenzen aus Bronchialkarzinomen |
EP1657311A4 (fr) * | 2003-07-11 | 2006-10-11 | Banyu Pharma Co Ltd | Methode d'evaluation de compose efficace dans le traitement de l'obesite |
US20070087984A1 (en) * | 2003-09-04 | 2007-04-19 | Xiuyuan Hu | Method of identifying agents that inhibit the growth of cancer cells |
WO2005083425A2 (fr) * | 2004-02-26 | 2005-09-09 | Bayer Healthcare Ag | Agents de diagnostic et de therapie destines aux maladies associees a la proteine kinase 13 activee par un mitogene (map3k13) |
EP2650907A3 (fr) | 2004-06-04 | 2014-10-08 | The Board of Trustees of the University of Illinois | Procédés et dispositifs permettant de fabriquer et d'assembler des éléments à semiconducteur imprimables |
KR101519038B1 (ko) | 2007-01-17 | 2015-05-11 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 프린팅기반 어셈블리에 의해 제조되는 광학 시스템 |
US8865489B2 (en) | 2009-05-12 | 2014-10-21 | The Board Of Trustees Of The University Of Illinois | Printed assemblies of ultrathin, microscale inorganic light emitting diodes for deformable and semitransparent displays |
US9442285B2 (en) | 2011-01-14 | 2016-09-13 | The Board Of Trustees Of The University Of Illinois | Optical component array having adjustable curvature |
WO2012158709A1 (fr) | 2011-05-16 | 2012-11-22 | The Board Of Trustees Of The University Of Illinois | Barrettes de del à gestion thermique assemblées par impression |
US8934965B2 (en) | 2011-06-03 | 2015-01-13 | The Board Of Trustees Of The University Of Illinois | Conformable actively multiplexed high-density surface electrode array for brain interfacing |
US9691873B2 (en) | 2011-12-01 | 2017-06-27 | The Board Of Trustees Of The University Of Illinois | Transient devices designed to undergo programmable transformations |
CN114181944B (zh) * | 2020-09-14 | 2023-10-03 | 中国科学院动物研究所 | 突变基因及构建短肢性侏儒症小型猪模型的方法和用途 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0572478B1 (fr) * | 1991-02-22 | 2005-09-07 | The Walter And Eliza Hall Institute Of Medical Research | Polypeptides et acides nucleiques de hbgad et higad et leur utilisation dans le traitement et le diagnostic de maladies associees a l'autoantigene gad. |
US5405941A (en) * | 1993-04-15 | 1995-04-11 | National Jewish Center For Immunology And Respiratory Medicine | MEKK protein, capable of phosphorylating MEK |
US5554523A (en) * | 1994-03-01 | 1996-09-10 | Children's Hospital Of Philadelphia | Nucleic acid sequences encoding human leucine-zipper protein-kinase |
AU3289599A (en) * | 1998-02-13 | 1999-08-30 | Cadus Pharmaceutical Corporation | Mekk1 proteins and fragments thereof for use in regulating apoptosis |
AU3354499A (en) * | 1998-03-16 | 1999-10-11 | Cadus Pharmaceutical Corporation | Human mekk proteins, corresponding nucleic acid molecules, and uses therefor |
JP2002538826A (ja) * | 1999-03-18 | 2002-11-19 | ザ ユニバーシティ オブ ブリストル | カエノラブジチス・エレガンス由来の多飽和脂肪酸(pufa)エロンガーゼ |
JP2002542782A (ja) * | 1999-04-23 | 2002-12-17 | インサイト・ゲノミックス・インコーポレイテッド | ヒト膜関連タンパク質 |
CA2342831A1 (fr) * | 1999-07-22 | 2001-02-01 | The University Of British Columbia | Enzyme biosynthetique d'acides gras a chaines longues de plantes |
CA2390421A1 (fr) * | 1999-11-12 | 2001-05-17 | Human Genome Sciences, Inc. | 24 proteines humaines secretees |
US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
EP1299538A2 (fr) * | 2000-06-20 | 2003-04-09 | Incyte Genomics, Inc. | Proteines secretees |
AU9174501A (en) * | 2000-08-11 | 2002-02-25 | Merck Patent Gmbh | Novel mitogen activated kinase |
US7297523B2 (en) * | 2000-11-29 | 2007-11-20 | Xenon Pharmaceuticals Inc. | Human elongase genes and uses thereof |
WO2002063006A2 (fr) * | 2001-02-06 | 2002-08-15 | Incyte Genomics, Inc. | Recepteurs et proteines associees aux membranes |
WO2002062974A2 (fr) * | 2001-02-08 | 2002-08-15 | Bayer Aktiengesellschaft | Regulation de la proteine humaine elongase hselo1 |
WO2002062975A2 (fr) * | 2001-02-08 | 2002-08-15 | Bayer Aktiengesellschaft | Regulation de la proteine humaine du type elongase hselo1 |
WO2002096943A1 (fr) * | 2001-05-25 | 2002-12-05 | Asahi Kasei Kabushiki Kaisha | Genes activant le stat6 |
AU2003231531A1 (en) * | 2002-04-24 | 2003-11-10 | Incyte Corporation | Kinases and phosphatases |
-
2002
- 2002-06-03 JP JP2003502009A patent/JP2004532638A/ja not_active Withdrawn
- 2002-06-03 CA CA002449479A patent/CA2449479A1/fr not_active Abandoned
- 2002-06-03 WO PCT/US2002/017739 patent/WO2002099068A2/fr not_active Application Discontinuation
- 2002-06-03 CA CA002448112A patent/CA2448112A1/fr not_active Abandoned
- 2002-06-03 EP EP02732039A patent/EP1402051A4/fr not_active Withdrawn
- 2002-06-03 WO PCT/US2002/017457 patent/WO2002098889A2/fr not_active Application Discontinuation
- 2002-06-03 AU AU2002314887A patent/AU2002314887A1/en not_active Abandoned
- 2002-06-03 WO PCT/US2002/017460 patent/WO2002098468A1/fr not_active Application Discontinuation
- 2002-06-03 JP JP2003502178A patent/JP2005514906A/ja not_active Withdrawn
- 2002-06-03 WO PCT/US2002/017465 patent/WO2002098891A2/fr not_active Application Discontinuation
- 2002-06-03 EP EP02741809A patent/EP1402262A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2448112A1 (fr) | 2002-12-12 |
WO2002098889A3 (fr) | 2003-03-27 |
CA2449479A1 (fr) | 2002-12-12 |
EP1402051A2 (fr) | 2004-03-31 |
WO2002098468A1 (fr) | 2002-12-12 |
EP1402262A4 (fr) | 2005-05-11 |
WO2002099068A3 (fr) | 2003-12-04 |
EP1402262A2 (fr) | 2004-03-31 |
WO2002099068A2 (fr) | 2002-12-12 |
JP2004532638A (ja) | 2004-10-28 |
WO2002098891A3 (fr) | 2003-05-30 |
AU2002314887A1 (en) | 2002-12-16 |
EP1402051A4 (fr) | 2005-08-17 |
WO2002098891A2 (fr) | 2002-12-12 |
WO2002098889A2 (fr) | 2002-12-12 |
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