JP2005511088A5 - - Google Patents
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- Publication number
- JP2005511088A5 JP2005511088A5 JP2003551302A JP2003551302A JP2005511088A5 JP 2005511088 A5 JP2005511088 A5 JP 2005511088A5 JP 2003551302 A JP2003551302 A JP 2003551302A JP 2003551302 A JP2003551302 A JP 2003551302A JP 2005511088 A5 JP2005511088 A5 JP 2005511088A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- gzip
- composition
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 14
- 102000004196 processed proteins & peptides Human genes 0.000 claims 14
- 108090000765 processed proteins & peptides Proteins 0.000 claims 14
- 150000001875 compounds Chemical class 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 239000005557 antagonist Substances 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 101150112998 ADIPOQ gene Proteins 0.000 claims 3
- 101150096655 APM1 gene Proteins 0.000 claims 3
- 101100162826 Dictyostelium discoideum apm2 gene Proteins 0.000 claims 3
- 101100053794 Homo sapiens ZBTB7C gene Proteins 0.000 claims 3
- 102100023250 Zinc finger and BTB domain-containing protein 7C Human genes 0.000 claims 3
- 230000037396 body weight Effects 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 1
- 235000021588 free fatty acids Nutrition 0.000 claims 1
- 230000002608 insulinlike Effects 0.000 claims 1
- 230000037356 lipid metabolism Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 238000000638 solvent extraction Methods 0.000 claims 1
- 230000004584 weight gain Effects 0.000 claims 1
- 235000019786 weight gain Nutrition 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32772501P | 2001-10-05 | 2001-10-05 | |
| PCT/IB2002/004598 WO2003050281A2 (en) | 2001-10-05 | 2002-10-03 | Fragments of the human zn-alpha2-glycolprotein and their use in methods of treatment of obesity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005511088A JP2005511088A (ja) | 2005-04-28 |
| JP2005511088A5 true JP2005511088A5 (https=) | 2005-12-22 |
| JP4423038B2 JP4423038B2 (ja) | 2010-03-03 |
Family
ID=23277766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003551302A Expired - Fee Related JP4423038B2 (ja) | 2001-10-05 | 2002-10-03 | Ｇｚｉｐポリヌクレオチドおよびポリペプチドならびにその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7402393B2 (https=) |
| EP (1) | EP1432803B1 (https=) |
| JP (1) | JP4423038B2 (https=) |
| AT (1) | ATE380868T1 (https=) |
| AU (1) | AU2002339678B2 (https=) |
| CA (1) | CA2461491A1 (https=) |
| DE (1) | DE60224064T2 (https=) |
| DK (1) | DK1432803T3 (https=) |
| ES (1) | ES2295415T3 (https=) |
| IL (2) | IL161233A0 (https=) |
| WO (1) | WO2003050281A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2350573T3 (es) | 2002-05-31 | 2011-01-25 | Merck Serono Biodevelopment Sas | Cabeza globular de obg3 ensanchada, homotrimérica y sus usos. |
| US8252520B2 (en) * | 2002-10-11 | 2012-08-28 | Taivex Therapeutics Corporation | Methods and compounds for inhibiting Hec1 activity for the treatment of proliferative diseases |
| EP1548445A3 (en) * | 2003-12-22 | 2005-11-23 | F. Hoffmann-La Roche Ag | Novel targets for obesity from fat tissue |
| US20100173829A1 (en) * | 2008-11-07 | 2010-07-08 | Aston University | Glycoproteins Having Lipid Mobilizing Properties and Therapeutic Uses Thereof |
| US8892184B2 (en) | 2010-10-18 | 2014-11-18 | Siemens Medical Solutions Usa, Inc. | Systems and methods for reducing interference in a dual modality imaging system |
| JP2015524808A (ja) * | 2012-07-25 | 2015-08-27 | ユニバーシティ・オブ・シンシナティ | アポリポタンパク質ａｉｖを用いたｉ型糖尿病の治療法 |
| CN111201029B (zh) * | 2017-09-29 | 2023-10-24 | 爱恩斯生物有限公司 | Zag来源肽及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9811465D0 (en) | 1998-05-29 | 1998-07-29 | Tisdale Michael J | Glycoproteins having lipid mobilising properties and therapeutic applications thereof |
| BR0107626A (pt) | 2000-01-14 | 2002-10-15 | Genset Sa | Cabeças globulares de obg3 e usos destes para diminuir a massa corporal |
| IL161234A0 (en) * | 2001-10-12 | 2004-09-27 | Genset Sa | Ngzipa, ngzipd, pgzipa and pgzipd polynucleotides and polypeptides and uses thereof |
-
2002
- 2002-10-03 DE DE60224064T patent/DE60224064T2/de not_active Expired - Lifetime
- 2002-10-03 AT AT02777726T patent/ATE380868T1/de active
- 2002-10-03 IL IL16123302A patent/IL161233A0/xx unknown
- 2002-10-03 EP EP02777726A patent/EP1432803B1/en not_active Expired - Lifetime
- 2002-10-03 CA CA002461491A patent/CA2461491A1/en not_active Abandoned
- 2002-10-03 DK DK02777726T patent/DK1432803T3/da active
- 2002-10-03 US US10/491,772 patent/US7402393B2/en not_active Expired - Fee Related
- 2002-10-03 AU AU2002339678A patent/AU2002339678B2/en not_active Ceased
- 2002-10-03 ES ES02777726T patent/ES2295415T3/es not_active Expired - Lifetime
- 2002-10-03 WO PCT/IB2002/004598 patent/WO2003050281A2/en not_active Ceased
- 2002-10-03 JP JP2003551302A patent/JP4423038B2/ja not_active Expired - Fee Related
-
2004
- 2004-04-01 IL IL161233A patent/IL161233A/en not_active IP Right Cessation
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