JP2005510503A5 - - Google Patents
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- Publication number
- JP2005510503A5 JP2005510503A5 JP2003538151A JP2003538151A JP2005510503A5 JP 2005510503 A5 JP2005510503 A5 JP 2005510503A5 JP 2003538151 A JP2003538151 A JP 2003538151A JP 2003538151 A JP2003538151 A JP 2003538151A JP 2005510503 A5 JP2005510503 A5 JP 2005510503A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- alkyl
- hydroxy
- aryl
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR8464A AUPR846401A0 (en) | 2001-10-25 | 2001-10-25 | 6-Hydroxy isoflavones, derivatives and medicaments involving same |
| PCT/AU2002/001442 WO2003035635A1 (en) | 2001-10-25 | 2002-10-25 | 6-hydroxy isoflavones, derivatives and medicaments involving same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005510503A JP2005510503A (ja) | 2005-04-21 |
| JP2005510503A5 true JP2005510503A5 (https=) | 2005-12-22 |
Family
ID=3832286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003538151A Pending JP2005510503A (ja) | 2001-10-25 | 2002-10-25 | ６−ヒドロキシイソフラボン、誘導体及びそれを含む薬剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050049424A1 (https=) |
| EP (1) | EP1448542A4 (https=) |
| JP (1) | JP2005510503A (https=) |
| CN (1) | CN1575289A (https=) |
| AU (1) | AUPR846401A0 (https=) |
| CA (1) | CA2464593A1 (https=) |
| HU (1) | HUP0401648A3 (https=) |
| IL (1) | IL161517A0 (https=) |
| MX (1) | MXPA04003874A (https=) |
| NO (1) | NO20042084L (https=) |
| WO (1) | WO2003035635A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69333624T2 (de) | 1992-05-19 | 2005-09-15 | Novogen Research Pty. Ltd., North Ryde | Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee |
| AUPP260798A0 (en) * | 1998-03-26 | 1998-04-23 | Novogen Research Pty Ltd | Treatment of medical related conditions with isoflavone containing extracts of clover |
| US20040072765A1 (en) * | 1999-04-28 | 2004-04-15 | Novogen Research Pty Ltd. | Cardiovascular and bone treatment using isoflavones |
| AUPQ520300A0 (en) * | 2000-01-21 | 2000-02-17 | Novogen Research Pty Ltd | Food product and process |
| EP1794141B1 (en) | 2004-09-21 | 2011-11-09 | Marshall Edwards, Inc. | Substituted chroman derivatives, medicaments and use in therapy |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| AU2006223257A1 (en) * | 2005-03-11 | 2006-09-21 | The Regents Of The University Of Michigan | Chromen-4-one inhibitors of anti-apoptotic Bcl-2 family members and the uses thereof |
| EP1861402B1 (en) * | 2005-03-24 | 2011-01-26 | Novogen Research Pty. Ltd. | Isoflavonoid dimers |
| TWI366565B (en) | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
| WO2009049214A2 (en) * | 2007-10-12 | 2009-04-16 | Northwestern University | Inhibition and treatment of prostate cancer metastasis |
| DK2310023T3 (en) | 2008-07-31 | 2016-12-12 | Sigma Tau Ind Farmaceuti | COMPOSITION, WHICH INCLUDES green tea AND EXTRACT OF POMEGRANATE FOR USE IN PREVENTING OR REDUCING THE PROGRESSION OF PROSTATE CANCER |
| WO2010042933A2 (en) | 2008-10-10 | 2010-04-15 | Northwestern University | Inhibition and treatment of prostate cancer metastasis |
| TWI492943B (zh) | 2008-12-05 | 2015-07-21 | 大塚製藥股份有限公司 | 喹啉酮化合物及藥學組成物（二） |
| WO2011043827A1 (en) * | 2009-10-09 | 2011-04-14 | Nestec S.A. | Methods for preventing or treating sarcopenia and muscle atrophy in animals |
| WO2011156889A1 (en) * | 2010-06-14 | 2011-12-22 | Trt Pharma Inc. | Novel modulators of nrf2 and uses thereof |
| JP6013349B2 (ja) | 2010-11-01 | 2016-10-25 | メイ ファーマ, インク.Mei Pharma, Inc. | 癌の処置のためのイソフラボノイド化合物および方法 |
| WO2012066330A1 (en) | 2010-11-17 | 2012-05-24 | Heptares Therapeutics Limited | Compounds useful as a2a receptor inhibitors |
| CN116139125A (zh) | 2015-02-02 | 2023-05-23 | 梅制药公司 | 联合治疗 |
| CN104829580B (zh) * | 2015-04-11 | 2017-11-24 | 云南中烟工业有限责任公司 | 烟草所含的异黄酮类化合物及其制备方法和应用 |
| US9718799B2 (en) | 2015-05-11 | 2017-08-01 | University Of Kentucky Research Foundation | 3-aryl-4H-chromene-4-ones as antineoplastic agents for the treatment of cancer |
| JP6099024B2 (ja) * | 2015-05-18 | 2017-03-22 | 株式会社東洋新薬 | ホスホジエステラーゼ３阻害剤 |
| AU2017247008B2 (en) | 2016-04-06 | 2022-04-07 | Noxopharm Limited | Isoflavonoid composition with improved pharmacokinetics |
| EP3439642A4 (en) | 2016-04-06 | 2019-11-13 | Noxopharm Limited | IMPROVEMENTS IN RADIOTHERAPY |
| CN107441079B (zh) * | 2017-08-22 | 2021-03-26 | 四川省中医药科学院 | 一种治疗心脑血管疾病的药物及其制备方法和用途 |
| CR20200553A (es) | 2018-04-18 | 2021-04-08 | Constellation Pharmaceuticals Inc | Moduladores de enzimas modificadoras de metilo, composiciones y usos de estos |
| CN120097995A (zh) | 2018-05-21 | 2025-06-06 | 星座制药公司 | 甲基修饰酶的调节剂、其组合物和用途 |
| KR102527205B1 (ko) | 2018-08-31 | 2023-05-03 | 서울대학교산학협력단 | 신규한 HIF-1α 억제제, 이의 제조방법 및 이를 유효성분으로 함유하는 신생혈관 관련 안질환의 예방 또는 치료용 약학적 조성물 |
| WO2020045856A1 (ko) * | 2018-08-31 | 2020-03-05 | 서울대학교 산학협력단 | 신규한 HIF-1α 억제제, 이의 제조방법 및 이를 유효성분으로 함유하는 신생혈관 관련 안질환의 예방 또는 치료용 약학적 조성물 |
| WO2020051644A1 (en) * | 2018-09-13 | 2020-03-19 | Norbio No. 2 Pty Ltd | Treatment of peripheral nervous tissue inflammation |
| CN109925308A (zh) * | 2018-12-29 | 2019-06-25 | 广东宏盈科技有限公司 | 异黄酮在制备治疗眼底黄斑病变的药物中的应用 |
| WO2021016414A1 (en) | 2019-07-24 | 2021-01-28 | Constellation Pharmaceuticals, Inc. | Crystalline forms of 7-chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2,4-dimethyl-n-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide |
| CN110590738B (zh) * | 2019-08-27 | 2022-03-01 | 温州大学 | 一种3,6-二甲基-1-仲胺基-7-氰基-8-羟基异喹啉类化合物的合成方法 |
| EP4125870A1 (en) | 2020-03-30 | 2023-02-08 | Noxopharm Limited | Methods for the treatment of inflammation associated with infection |
| WO2021195698A1 (en) * | 2020-03-30 | 2021-10-07 | Noxopharm Limited | Methods for the treatment of inflammation associated with infection |
| CN117384124B (zh) * | 2022-07-04 | 2025-08-01 | 安徽中医药大学 | Hdac抑制剂、组合物及其应用 |
| JP7780235B2 (ja) * | 2023-07-24 | 2025-12-04 | 国立大学法人 大分大学 | 抗酸化化合物 |
| CN118373794B (zh) * | 2024-04-17 | 2025-08-29 | 中国中医科学院中药研究所 | 一种异黄酮类化合物及其制备方法和在制药中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4264509A (en) * | 1977-06-08 | 1981-04-28 | Z-L Limited Partnership | Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same |
| GB8626344D0 (en) * | 1986-11-04 | 1986-12-03 | Zyma Sa | Bicyclic compounds |
| DE69333624T2 (de) * | 1992-05-19 | 2005-09-15 | Novogen Research Pty. Ltd., North Ryde | Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee |
| AUPO203996A0 (en) * | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
| GB9621757D0 (en) * | 1996-10-18 | 1996-12-11 | Ciba Geigy Ag | Phenyl-substituted bicyclic heterocyclyl derivatives and their use |
| US5733926A (en) * | 1996-12-13 | 1998-03-31 | Gorbach; Sherwood L. | Isoflavonoids for treatment and prevention of alzheimer dementia and reduced cognitive functions |
| US6146668A (en) * | 1997-04-28 | 2000-11-14 | Novogen, Inc. | Preparation of isoflavones from legumes |
| WO1998050026A1 (en) * | 1997-05-01 | 1998-11-12 | Novogen Inc | Treatment or prevention of menopausal symptoms and osteoporosis |
| WO1999049862A1 (en) * | 1998-03-30 | 1999-10-07 | The University Of Mississippi | Isoflavones for treating giardiasis and malaria |
| AUPQ008299A0 (en) * | 1999-04-30 | 1999-05-27 | G.J. Consultants Pty Ltd | Isoflavone metabolites |
| FI20001593A7 (fi) * | 2000-07-03 | 2002-01-04 | Orion Yhtymo Oyj | Comt-entsyymiõ inhiboivaa aktiivisuutta omaavia kumariinijohdannaisia |
| WO2002074307A1 (en) * | 2001-03-16 | 2002-09-26 | Novogen Research Pty Ltd | Treatment of restenosis |
-
2001
- 2001-10-25 AU AUPR8464A patent/AUPR846401A0/en not_active Abandoned
-
2002
- 2002-10-25 CA CA002464593A patent/CA2464593A1/en not_active Abandoned
- 2002-10-25 HU HU0401648A patent/HUP0401648A3/hu unknown
- 2002-10-25 MX MXPA04003874A patent/MXPA04003874A/es unknown
- 2002-10-25 EP EP02771876A patent/EP1448542A4/en not_active Withdrawn
- 2002-10-25 IL IL16151702A patent/IL161517A0/xx unknown
- 2002-10-25 US US10/493,390 patent/US20050049424A1/en not_active Abandoned
- 2002-10-25 CN CNA028211154A patent/CN1575289A/zh active Pending
- 2002-10-25 WO PCT/AU2002/001442 patent/WO2003035635A1/en not_active Ceased
- 2002-10-25 JP JP2003538151A patent/JP2005510503A/ja active Pending
-
2004
- 2004-05-21 NO NO20042084A patent/NO20042084L/no unknown
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