JP2005510469A5 - - Google Patents
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- Publication number
- JP2005510469A5 JP2005510469A5 JP2003528859A JP2003528859A JP2005510469A5 JP 2005510469 A5 JP2005510469 A5 JP 2005510469A5 JP 2003528859 A JP2003528859 A JP 2003528859A JP 2003528859 A JP2003528859 A JP 2003528859A JP 2005510469 A5 JP2005510469 A5 JP 2005510469A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- lysine
- sequence
- serine
- acetylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 69
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 66
- 239000004472 Lysine Substances 0.000 claims 66
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 claims 63
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 60
- 108090000765 processed proteins & peptides Proteins 0.000 claims 27
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 150000001413 amino acids Chemical class 0.000 claims 7
- 208000023275 Autoimmune disease Diseases 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 241001529936 Murinae Species 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 230000004481 post-translational protein modification Effects 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 230000021736 acetylation Effects 0.000 claims 2
- 238000006640 acetylation reaction Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 210000000056 organ Anatomy 0.000 claims 2
- 230000026731 phosphorylation Effects 0.000 claims 2
- 238000006366 phosphorylation reaction Methods 0.000 claims 2
- 230000009885 systemic effect Effects 0.000 claims 2
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 208000003250 Mixed connective tissue disease Diseases 0.000 claims 1
- 108010061100 Nucleoproteins Proteins 0.000 claims 1
- 102000011931 Nucleoproteins Human genes 0.000 claims 1
- 108010076622 SS-A antigen Proteins 0.000 claims 1
- 208000021386 Sjogren Syndrome Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000018631 connective tissue disease Diseases 0.000 claims 1
- 210000000987 immune system Anatomy 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 210000003705 ribosome Anatomy 0.000 claims 1
- -1 splicesomes Proteins 0.000 claims 1
- 208000035408 type 1 diabetes mellitus 1 Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0112041A FR2829768B1 (fr) | 2001-09-18 | 2001-09-18 | Utilisation de peptides comportant des modifications de type post-traductionnel dans le cadre du traitement de pathologies auto-immunes |
| PCT/FR2002/003186 WO2003025014A2 (fr) | 2001-09-18 | 2002-09-18 | Utilisation de peptides comportant des modifications de type post-traductionnel dans le cadre du traitement de pathologies auto-immunes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005510469A JP2005510469A (ja) | 2005-04-21 |
| JP2005510469A5 true JP2005510469A5 (https=) | 2005-12-22 |
| JP4160505B2 JP4160505B2 (ja) | 2008-10-01 |
Family
ID=8867384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003528859A Expired - Lifetime JP4160505B2 (ja) | 2001-09-18 | 2002-09-18 | 自己免疫疾患の治療の構想における翻訳後型修飾を含むペプチドの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7872098B1 (https=) |
| EP (2) | EP1427755A2 (https=) |
| JP (1) | JP4160505B2 (https=) |
| AU (1) | AU2002362383B2 (https=) |
| CA (1) | CA2460704A1 (https=) |
| FR (1) | FR2829768B1 (https=) |
| WO (1) | WO2003025014A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60234843D1 (de) * | 2001-09-06 | 2010-02-04 | Centre Nat Rech Scient | Modifizierte peptide und deren verwendung zur behandlung von autoimmunkrankheiten |
| FR2931360B1 (fr) * | 2008-05-20 | 2012-05-18 | Centre Nat Rech Scient | Nanoparticules contenant un peptide, vecteurs les contenant et utilisations pharmaceutiques desdits nanoparticules et vecteurs |
| ES2618402T3 (es) * | 2011-12-13 | 2017-06-21 | Centre National De La Recherche Scientifique | Péptidos modificados y su uso para tratar enfermedades autoinmunitarias |
| US10213482B2 (en) | 2014-12-12 | 2019-02-26 | Immupharma France Sa | Methods of treating chronic inflammatory diseases |
| WO2021198135A1 (en) * | 2020-03-29 | 2021-10-07 | Immupharma France Sa | Method of treating viral infections |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60234843D1 (de) * | 2001-09-06 | 2010-02-04 | Centre Nat Rech Scient | Modifizierte peptide und deren verwendung zur behandlung von autoimmunkrankheiten |
-
2001
- 2001-09-18 FR FR0112041A patent/FR2829768B1/fr not_active Expired - Lifetime
-
2002
- 2002-09-18 US US10/489,967 patent/US7872098B1/en active Active
- 2002-09-18 CA CA002460704A patent/CA2460704A1/fr not_active Abandoned
- 2002-09-18 EP EP02798771A patent/EP1427755A2/fr not_active Ceased
- 2002-09-18 AU AU2002362383A patent/AU2002362383B2/en not_active Expired
- 2002-09-18 EP EP10183969A patent/EP2338908A1/fr not_active Withdrawn
- 2002-09-18 JP JP2003528859A patent/JP4160505B2/ja not_active Expired - Lifetime
- 2002-09-18 WO PCT/FR2002/003186 patent/WO2003025014A2/fr not_active Ceased
-
2010
- 2010-10-27 US US12/913,232 patent/US8475800B2/en not_active Expired - Lifetime
-
2013
- 2013-06-11 US US13/914,997 patent/US20140004136A1/en not_active Abandoned
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