JP2005506371A5 - - Google Patents
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- Publication number
- JP2005506371A5 JP2005506371A5 JP2003537648A JP2003537648A JP2005506371A5 JP 2005506371 A5 JP2005506371 A5 JP 2005506371A5 JP 2003537648 A JP2003537648 A JP 2003537648A JP 2003537648 A JP2003537648 A JP 2003537648A JP 2005506371 A5 JP2005506371 A5 JP 2005506371A5
- Authority
- JP
- Japan
- Prior art keywords
- cox
- bisphosphonate
- inhibitors
- combination
- certain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940122361 Bisphosphonate Drugs 0.000 description 3
- 150000004663 bisphosphonates Chemical class 0.000 description 3
- 102000010907 Cyclooxygenase 2 Human genes 0.000 description 2
- 108010037462 Cyclooxygenase 2 Proteins 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 229940111134 coxibs Drugs 0.000 description 2
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34592101P | 2001-10-19 | 2001-10-19 | |
| PCT/EP2002/011696 WO2003035081A1 (en) | 2001-10-19 | 2002-10-18 | Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005506371A JP2005506371A (ja) | 2005-03-03 |
| JP2005506371A5 true JP2005506371A5 (enExample) | 2009-09-24 |
Family
ID=23357099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003537648A Pending JP2005506371A (ja) | 2001-10-19 | 2002-10-18 | ビスホスホネート、ｃｏｘ−２阻害剤およびタキソールを組合せて含んでなる、悪性腫瘍の処置に使用するための医薬組成物 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7345088B2 (enExample) |
| EP (1) | EP1443942B1 (enExample) |
| JP (1) | JP2005506371A (enExample) |
| KR (1) | KR20040066103A (enExample) |
| CN (1) | CN100372539C (enExample) |
| AT (1) | ATE382347T1 (enExample) |
| AU (1) | AU2002363089B2 (enExample) |
| BR (1) | BR0213410A (enExample) |
| CA (1) | CA2461085A1 (enExample) |
| CO (1) | CO5570672A2 (enExample) |
| DE (1) | DE60224429T2 (enExample) |
| DK (1) | DK1443942T3 (enExample) |
| EC (1) | ECSP045054A (enExample) |
| ES (1) | ES2301710T3 (enExample) |
| HU (1) | HUP0402061A3 (enExample) |
| IL (2) | IL161090A0 (enExample) |
| MX (1) | MXPA04003671A (enExample) |
| NO (1) | NO20042056L (enExample) |
| NZ (1) | NZ532282A (enExample) |
| PL (1) | PL367707A1 (enExample) |
| PT (1) | PT1443942E (enExample) |
| RU (1) | RU2317819C2 (enExample) |
| SI (1) | SI1443942T1 (enExample) |
| WO (1) | WO2003035081A1 (enExample) |
| ZA (1) | ZA200402089B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0204756D0 (en) * | 2002-02-28 | 2002-04-17 | Novartis Ag | Organic compounds |
| GB0328040D0 (en) * | 2003-12-03 | 2004-01-07 | Coleman Robert E | Pharmaceutical uses of bisphosphonates |
| FR2939314A1 (fr) * | 2008-12-04 | 2010-06-11 | Univ Victor Segalen Bordeaux 2 | Nouvelles compositions et methodes pour la potentialisation des signaux d'apoptose dans les cellules tumorales |
| US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| PT2459176T (pt) | 2009-07-31 | 2017-12-11 | Gruenenthal Gmbh | Método de cristalização e biodisponibilidade |
| US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| WO2012071517A2 (en) | 2010-11-24 | 2012-05-31 | Thar Pharmaceuticals, Inc. | Novel crystalline forms |
| US10195218B2 (en) | 2016-05-31 | 2019-02-05 | Grunenthal Gmbh | Crystallization method and bioavailability |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1187130A (zh) * | 1995-06-06 | 1998-07-08 | 麦克公司 | 用二磷酸盐预防与免疫抑制疗法有关的骨损失 |
| CA2356462A1 (en) * | 1998-12-23 | 2000-07-06 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| CA2396593A1 (en) * | 2000-01-28 | 2001-08-02 | Merck & Co., Inc. | Treatment or prevention of prostate cancer with a cox-2 selective inhibiting drug |
-
2002
- 2002-10-18 EP EP02801899A patent/EP1443942B1/en not_active Expired - Lifetime
- 2002-10-18 NZ NZ532282A patent/NZ532282A/en unknown
- 2002-10-18 AU AU2002363089A patent/AU2002363089B2/en not_active Ceased
- 2002-10-18 BR BR0213410-1A patent/BR0213410A/pt not_active IP Right Cessation
- 2002-10-18 AT AT02801899T patent/ATE382347T1/de not_active IP Right Cessation
- 2002-10-18 HU HU0402061A patent/HUP0402061A3/hu unknown
- 2002-10-18 MX MXPA04003671A patent/MXPA04003671A/es active IP Right Grant
- 2002-10-18 PT PT02801899T patent/PT1443942E/pt unknown
- 2002-10-18 DE DE60224429T patent/DE60224429T2/de not_active Expired - Fee Related
- 2002-10-18 KR KR10-2004-7005630A patent/KR20040066103A/ko not_active Ceased
- 2002-10-18 CA CA002461085A patent/CA2461085A1/en not_active Abandoned
- 2002-10-18 PL PL02367707A patent/PL367707A1/xx not_active Application Discontinuation
- 2002-10-18 WO PCT/EP2002/011696 patent/WO2003035081A1/en not_active Ceased
- 2002-10-18 DK DK02801899T patent/DK1443942T3/da active
- 2002-10-18 RU RU2004115337/15A patent/RU2317819C2/ru not_active IP Right Cessation
- 2002-10-18 CN CNB028207823A patent/CN100372539C/zh not_active Expired - Fee Related
- 2002-10-18 US US10/493,042 patent/US7345088B2/en not_active Expired - Fee Related
- 2002-10-18 IL IL16109002A patent/IL161090A0/xx unknown
- 2002-10-18 SI SI200230676T patent/SI1443942T1/sl unknown
- 2002-10-18 JP JP2003537648A patent/JP2005506371A/ja active Pending
- 2002-10-18 ES ES02801899T patent/ES2301710T3/es not_active Expired - Lifetime
-
2004
- 2004-03-16 ZA ZA200402089A patent/ZA200402089B/en unknown
- 2004-03-25 IL IL161090A patent/IL161090A/en not_active IP Right Cessation
- 2004-04-08 EC EC2004005054A patent/ECSP045054A/es unknown
- 2004-04-15 CO CO04034537A patent/CO5570672A2/es not_active Application Discontinuation
- 2004-05-18 NO NO20042056A patent/NO20042056L/no not_active Application Discontinuation
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