JP2005505503A5 - - Google Patents
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- Publication number
- JP2005505503A5 JP2005505503A5 JP2002587459A JP2002587459A JP2005505503A5 JP 2005505503 A5 JP2005505503 A5 JP 2005505503A5 JP 2002587459 A JP2002587459 A JP 2002587459A JP 2002587459 A JP2002587459 A JP 2002587459A JP 2005505503 A5 JP2005505503 A5 JP 2005505503A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- peptides
- positions
- protein
- hpv16
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 96
- 102000004196 processed proteins & peptides Human genes 0.000 claims 43
- 239000000203 mixture Substances 0.000 claims 25
- 108090000623 proteins and genes Proteins 0.000 claims 23
- 102000004169 proteins and genes Human genes 0.000 claims 19
- 241000341655 Human papillomavirus type 16 Species 0.000 claims 13
- 101001100327 Homo sapiens RNA-binding protein 45 Proteins 0.000 claims 6
- 102100038823 RNA-binding protein 45 Human genes 0.000 claims 6
- 101000954493 Human papillomavirus type 16 Protein E6 Proteins 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 150000001413 amino acids Chemical group 0.000 claims 4
- 108700028369 Alleles Proteins 0.000 claims 3
- 101000691214 Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) 50S ribosomal protein L44e Proteins 0.000 claims 3
- 101000767631 Human papillomavirus type 16 Protein E7 Proteins 0.000 claims 3
- 108010028921 Lipopeptides Proteins 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- 108010039343 HLA-DRB1 Chains Proteins 0.000 claims 2
- 230000027455 binding Effects 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 101150034979 DRB3 gene Proteins 0.000 claims 1
- 101150082328 DRB5 gene Proteins 0.000 claims 1
- 238000011510 Elispot assay Methods 0.000 claims 1
- HVLSXIKZNLPZJJ-TXZCQADKSA-N HA peptide Chemical compound C([C@@H](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](C)C(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 HVLSXIKZNLPZJJ-TXZCQADKSA-N 0.000 claims 1
- 102100040482 HLA class II histocompatibility antigen, DR beta 3 chain Human genes 0.000 claims 1
- 102100028636 HLA class II histocompatibility antigen, DR beta 4 chain Human genes 0.000 claims 1
- 102100040485 HLA class II histocompatibility antigen, DRB1 beta chain Human genes 0.000 claims 1
- 108010058597 HLA-DR Antigens Proteins 0.000 claims 1
- 102000006354 HLA-DR Antigens Human genes 0.000 claims 1
- 108010061311 HLA-DRB3 Chains Proteins 0.000 claims 1
- 108010040960 HLA-DRB4 Chains Proteins 0.000 claims 1
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 101000854908 Homo sapiens WD repeat-containing protein 11 Proteins 0.000 claims 1
- 101100278514 Oryza sativa subsp. japonica DRB2 gene Proteins 0.000 claims 1
- 101100117565 Oryza sativa subsp. japonica DRB4 gene Proteins 0.000 claims 1
- 101100117569 Oryza sativa subsp. japonica DRB6 gene Proteins 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 241000223960 Plasmodium falciparum Species 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 230000006052 T cell proliferation Effects 0.000 claims 1
- 108010055044 Tetanus Toxin Proteins 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 102100020705 WD repeat-containing protein 11 Human genes 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 238000001516 cell proliferation assay Methods 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- BFMYDTVEBKDAKJ-UHFFFAOYSA-L disodium;(2',7'-dibromo-3',6'-dioxido-3-oxospiro[2-benzofuran-1,9'-xanthene]-4'-yl)mercury;hydrate Chemical group O.[Na+].[Na+].O1C(=O)C2=CC=CC=C2C21C1=CC(Br)=C([O-])C([Hg])=C1OC1=C2C=C(Br)C([O-])=C1 BFMYDTVEBKDAKJ-UHFFFAOYSA-L 0.000 claims 1
- 238000003114 enzyme-linked immunosorbent spot assay Methods 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 229940118376 tetanus toxin Drugs 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0105980A FR2824326B1 (fr) | 2001-05-04 | 2001-05-04 | Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications |
| PCT/FR2002/001533 WO2002090382A2 (fr) | 2001-05-04 | 2002-05-03 | Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005505503A JP2005505503A (ja) | 2005-02-24 |
| JP2005505503A5 true JP2005505503A5 (enExample) | 2005-12-22 |
Family
ID=8862980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002587459A Withdrawn JP2005505503A (ja) | 2001-05-04 | 2002-05-03 | Ｅ６及び／又はｅ７パピローマウイルスタンパク質に由来するペプチドの混合物並びにその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7488791B2 (enExample) |
| EP (1) | EP1383535A2 (enExample) |
| JP (1) | JP2005505503A (enExample) |
| AU (1) | AU2002302713A1 (enExample) |
| CA (1) | CA2446062A1 (enExample) |
| FR (1) | FR2824326B1 (enExample) |
| WO (1) | WO2002090382A2 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| DE10336916B4 (de) * | 2003-08-07 | 2015-02-19 | Danfoss A/S | Regelventil und Wärmetauscheranordnung |
| WO2006037059A2 (en) * | 2004-09-27 | 2006-04-06 | The Johns Hopkins Universtiy | Point-of-care mass spectrometer system |
| JP2008044848A (ja) * | 2004-11-30 | 2008-02-28 | Univ Kurume | Ｈｌａ−ａ２４拘束性腫瘍抗原ペプチド |
| US7972776B2 (en) * | 2005-11-15 | 2011-07-05 | Oncohealth Corporation | Protein chips for HPV detection |
| ES2310072B1 (es) * | 2005-12-23 | 2009-11-16 | Proyecto De Biomedicina Cima, S.L. | Nuevos peptidos determinantes antigenicos t colaboradores (/dth). |
| US8859218B2 (en) * | 2008-06-13 | 2014-10-14 | Oncohealth Corp. | In situ detection of early stages and late stages HPV infection |
| US8968995B2 (en) * | 2008-11-12 | 2015-03-03 | Oncohealth Corp. | Detection, screening, and diagnosis of HPV-associated cancers |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| AU2013205259B2 (en) * | 2007-05-31 | 2015-06-11 | Isa Pharmaceuticals B.V. | HPV epitopes targeted by T cells infiltrating cervical malignancies for use in vaccines |
| ES2496916T3 (es) | 2007-05-31 | 2014-09-22 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Epítopo de HPV al que se dirigen células T que infiltran tumores malignos cervicales para su uso en vacunas |
| KR20090103571A (ko) * | 2008-03-28 | 2009-10-01 | 바이오코아 주식회사 | 면역성 펩타이드 및 그 펩타이드를 포함하는 ｈｐｖ 관련질환 예방 또는 치료용 조성물 |
| WO2009129227A1 (en) | 2008-04-17 | 2009-10-22 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
| EP2427763A4 (en) | 2009-05-07 | 2013-08-21 | Oncohealth Corp | IDENTIFICATION OF HIGH GRADE OR CIN2 FOR DETECTION, MONITORING AND DIAGNOSIS, AT EARLY STAGES AND ADVANCED STAGES, OF HUMAN PAPILLOMAVIRUS (HPV) AND HPV ASSOCIATED CANCERS |
| AR074485A1 (es) * | 2009-12-04 | 2011-01-19 | Consejo Nac Invest Cient Tec | Vacuna contra lesiones neoplasicas o cancerosas causadas por el virus del papiloma humano (vph), procedimientos, usos y metodos |
| EP2521914A4 (en) | 2010-01-08 | 2013-07-10 | Oncohealth Corp | CELL-BASED HPV IMMUNOTESTS HAVE A HIGH PERFORMANCE FOR DIAGNOSIS AND SCANNING OF HPV ASSOCIATED CANCER |
| CN102060929A (zh) * | 2010-06-07 | 2011-05-18 | 夏书奇 | T细胞免疫平衡肽 |
| CN103282375B (zh) | 2010-12-02 | 2017-01-11 | 比奥诺尔免疫有限公司 | 肽支架设计 |
| ES2607148T3 (es) | 2012-05-08 | 2017-03-29 | The Johns Hopkins University | Métodos y composiciones para infusión de poblaciones seleccionadas de linfocitos alogénicos con prendimiento transitorio para tratar cáncer |
| CN105163753B (zh) | 2012-06-15 | 2018-12-21 | Pds生物科技公司 | 阳离子脂质疫苗组合物和使用方法 |
| EP2897639A4 (en) | 2012-09-21 | 2016-05-04 | Frank Bedu-Addo | IMPROVED VACCINATE COMPOSITIONS AND METHODS OF USE |
| FR3008099B1 (fr) | 2013-07-05 | 2020-08-07 | Commissariat Energie Atomique | Peptides immunogenes de l'antigene tumoral cycline b1 |
| EP3058956A1 (en) | 2015-02-23 | 2016-08-24 | Institut Curie | Combined vaccination/radioterapy for cancer treatment |
| CA3005251A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| EA201990071A1 (ru) | 2016-06-20 | 2019-06-28 | АйЭсЭй ФАРМАСЬЮТИКАЛЗ Б.В. | Композиция пептидной вакцины |
| EP3267119A1 (en) | 2016-07-07 | 2018-01-10 | E.ON Sverige AB | Combined heating and cooling system |
| CN110035765B (zh) * | 2016-10-05 | 2024-04-02 | Pds生物科技公司 | 新型hpv16非hla限制性t细胞疫苗、组合物及其使用方法 |
| WO2019145792A1 (en) * | 2018-01-24 | 2019-08-01 | The Council Of The Queensland Institute Of Medical Research | Hpv immunotherapy |
| JP2021522239A (ja) * | 2018-04-26 | 2021-08-30 | アジェナス インコーポレイテッド | 熱ショックタンパク質結合ペプチド組成物およびその使用方法 |
| EP3886886A4 (en) * | 2018-11-28 | 2022-08-24 | The General Hospital Corporation | T cell-directed anti-cancer vaccines against commensal viruses |
| MX2022009255A (es) * | 2020-02-10 | 2023-02-23 | Univ Johns Hopkins | Inmunoterapia contra cáncer usando transfusiones de celulas t alogenicas cd4+ específicas de tumor. |
| EP4281106A4 (en) * | 2021-01-21 | 2024-12-25 | The General Hospital Corporation | T-CELL-TARGETED ANTICANCER VACCINES AGAINST COMMENSAL VIRUSES FOR THE TREATMENT OF MUCOSAIC CARCINOMAS |
| WO2024223299A2 (en) | 2023-04-26 | 2024-10-31 | Isa Pharmaceuticals B.V. | Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor |
| CN119569831A (zh) * | 2024-12-13 | 2025-03-07 | 深圳锦时生物科技有限公司 | 一种活性多肽及在预防和/或治疗hpv中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9001705D0 (sv) * | 1990-05-11 | 1990-05-11 | Medscand Ab | Saett foer diagnostik av virusbaerande tumoerer genom immunoassay |
| US5932412A (en) * | 1990-05-11 | 1999-08-03 | Euro-Diagnostica Ab | Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes |
| PT523391E (pt) * | 1991-07-13 | 2003-08-29 | Dade Behring Marburg Gmbh | Utilizacao dos peptidos derivados dos genes hpv-16 e6 e e7 para fins de diagnostico |
| RS50101B (sr) * | 1996-02-24 | 2009-01-22 | Boehringer Ingelheim International Gmbh., | Farmaceutski preparati za imunomodulaciju |
| JP2002500198A (ja) * | 1998-01-09 | 2002-01-08 | サーカシア リミテッド | 脱感作のための方法及び組成物 |
| FR2794370B1 (fr) * | 1999-06-03 | 2003-10-17 | Biovector Therapeutics | Fragments proteiques polyepitopiques, leur obtention et leurs utilisations notamment en vaccination |
| JP2003509465A (ja) * | 1999-07-19 | 2003-03-11 | エピミューン， インコーポレイテッド | ペプチドおよび核酸組成物を使用する、ｃ型肝炎ウイルスに対する細胞性免疫応答の誘導 |
| SE9903031D0 (sv) * | 1999-08-27 | 1999-08-27 | Eurodiagnostica Ab | Peptide mixture and vaccine against a chronic viral infection |
| AU785319B2 (en) * | 1999-09-16 | 2007-01-11 | Eisai Inc. | Nucleic acids encoding polyepitope polypeptides |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| WO2001024810A1 (en) * | 1999-10-05 | 2001-04-12 | Epimmune Inc. | Inducing cellular immune responses to human immunodeficiency virus-1 using peptide and nucleic acid compositions |
-
2001
- 2001-05-04 FR FR0105980A patent/FR2824326B1/fr not_active Expired - Fee Related
-
2002
- 2002-05-03 EP EP02730391A patent/EP1383535A2/fr not_active Withdrawn
- 2002-05-03 CA CA 2446062 patent/CA2446062A1/fr not_active Abandoned
- 2002-05-03 JP JP2002587459A patent/JP2005505503A/ja not_active Withdrawn
- 2002-05-03 WO PCT/FR2002/001533 patent/WO2002090382A2/fr not_active Ceased
- 2002-05-03 US US10/476,570 patent/US7488791B2/en not_active Expired - Fee Related
- 2002-05-03 AU AU2002302713A patent/AU2002302713A1/en not_active Abandoned
-
2008
- 2008-12-31 US US12/347,471 patent/US20100203080A1/en not_active Abandoned
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