JP2005253959A5 - - Google Patents
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- Publication number
- JP2005253959A5 JP2005253959A5 JP2005040910A JP2005040910A JP2005253959A5 JP 2005253959 A5 JP2005253959 A5 JP 2005253959A5 JP 2005040910 A JP2005040910 A JP 2005040910A JP 2005040910 A JP2005040910 A JP 2005040910A JP 2005253959 A5 JP2005253959 A5 JP 2005253959A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- cladribine
- rapamycin
- implantable structure
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PTOAARAWEBMLNO-KVQBGUIXSA-N Cladribine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@H]1C[C@H](O)[C@@H](CO)O1 PTOAARAWEBMLNO-KVQBGUIXSA-N 0.000 claims 7
- 229960002436 cladribine Drugs 0.000 claims 7
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 7
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 7
- 229960002930 sirolimus Drugs 0.000 claims 7
- 239000011248 coating agent Substances 0.000 claims 6
- 238000000576 coating method Methods 0.000 claims 6
- 239000000463 material Substances 0.000 claims 5
- 208000037803 restenosis Diseases 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- 238000011287 therapeutic dose Methods 0.000 claims 3
- 230000003872 anastomosis Effects 0.000 claims 2
- 238000010828 elution Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000004925 Acrylic resin Substances 0.000 claims 1
- 229920000178 Acrylic resin Polymers 0.000 claims 1
- 208000024248 Vascular System injury Diseases 0.000 claims 1
- 208000012339 Vascular injury Diseases 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 229920002313 fluoropolymer Polymers 0.000 claims 1
- 239000004811 fluoropolymer Substances 0.000 claims 1
- 239000002861 polymer material Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US780596 | 2004-02-18 | ||
| US10/780,596 US7806924B2 (en) | 2004-02-18 | 2004-02-18 | Implantable structures for local vascular delivery of cladribine in combination with rapamycin for restenosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005253959A JP2005253959A (ja) | 2005-09-22 |
| JP2005253959A5 true JP2005253959A5 (enExample) | 2011-03-24 |
| JP4846246B2 JP4846246B2 (ja) | 2011-12-28 |
Family
ID=34750452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005040910A Expired - Fee Related JP4846246B2 (ja) | 2004-02-18 | 2005-02-17 | 脈管の傷害後の再狭窄を防ぐためのラパマイシンとの組み合わせにおけるクラドリビンの局所的脈管配給 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7806924B2 (enExample) |
| EP (1) | EP1570871B1 (enExample) |
| JP (1) | JP4846246B2 (enExample) |
| AT (1) | ATE442169T1 (enExample) |
| CA (1) | CA2497216C (enExample) |
| DE (1) | DE602005016479D1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8986369B2 (en) | 2010-12-01 | 2015-03-24 | Zorion Medical, Inc. | Magnesium-based absorbable implants |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7611533B2 (en) | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| US7572245B2 (en) * | 2003-09-15 | 2009-08-11 | Atrium Medical Corporation | Application of a therapeutic substance to a tissue location using an expandable medical device |
| US6955661B1 (en) | 1999-01-25 | 2005-10-18 | Atrium Medical Corporation | Expandable fluoropolymer device for delivery of therapeutic agents and method of making |
| US7947015B2 (en) * | 1999-01-25 | 2011-05-24 | Atrium Medical Corporation | Application of a therapeutic substance to a tissue location using an expandable medical device |
| US8038708B2 (en) | 2001-02-05 | 2011-10-18 | Cook Medical Technologies Llc | Implantable device with remodelable material and covering material |
| US7056338B2 (en) | 2003-03-28 | 2006-06-06 | Conor Medsystems, Inc. | Therapeutic agent delivery device with controlled therapeutic agent release rates |
| DE60235775D1 (de) * | 2001-11-08 | 2010-05-06 | Ziscoat N V | Intraluminale Vorrichtung mit einer therapeutisches-mittel enthaltenden Beschichtung |
| WO2004087214A1 (en) | 2003-03-28 | 2004-10-14 | Conor Medsystems, Inc. | Implantable medical device with beneficial agent concentration gradient |
| US8021331B2 (en) * | 2003-09-15 | 2011-09-20 | Atrium Medical Corporation | Method of coating a folded medical device |
| US20050113687A1 (en) * | 2003-09-15 | 2005-05-26 | Atrium Medical Corporation | Application of a therapeutic substance to a tissue location using a porous medical device |
| US7244441B2 (en) * | 2003-09-25 | 2007-07-17 | Scios, Inc. | Stents and intra-luminal prostheses containing map kinase inhibitors |
| US20050249776A1 (en) * | 2003-12-19 | 2005-11-10 | Chen Chao C | Coated aneurysmal repair device |
| US8747881B2 (en) | 2003-12-19 | 2014-06-10 | Cordis Corporation | Intraluminal medical devices in combination with therapeutic agents |
| US8652502B2 (en) | 2003-12-19 | 2014-02-18 | Cordis Corporation | Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury |
| EP2594259A1 (en) | 2004-08-04 | 2013-05-22 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| US9012506B2 (en) | 2004-09-28 | 2015-04-21 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
| US8312836B2 (en) | 2004-09-28 | 2012-11-20 | Atrium Medical Corporation | Method and apparatus for application of a fresh coating on a medical device |
| WO2006036983A2 (en) | 2004-09-28 | 2006-04-06 | Atrium Medical Corporation | Pre-dried drug delivery coating for use with a stent |
| US9000040B2 (en) | 2004-09-28 | 2015-04-07 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
| US9801982B2 (en) | 2004-09-28 | 2017-10-31 | Atrium Medical Corporation | Implantable barrier device |
| WO2006036970A2 (en) * | 2004-09-28 | 2006-04-06 | Atrium Medical Corporation | Method of thickening a coating using a drug |
| US8367099B2 (en) | 2004-09-28 | 2013-02-05 | Atrium Medical Corporation | Perforated fatty acid films |
| US8124127B2 (en) | 2005-10-15 | 2012-02-28 | Atrium Medical Corporation | Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings |
| WO2006036964A2 (en) | 2004-09-28 | 2006-04-06 | Atrium Medical Corporation | Barrier layer |
| US9278161B2 (en) | 2005-09-28 | 2016-03-08 | Atrium Medical Corporation | Tissue-separating fatty acid adhesion barrier |
| US9427423B2 (en) | 2009-03-10 | 2016-08-30 | Atrium Medical Corporation | Fatty-acid based particles |
| US8574627B2 (en) | 2006-11-06 | 2013-11-05 | Atrium Medical Corporation | Coated surgical mesh |
| US20070116736A1 (en) * | 2005-11-23 | 2007-05-24 | Argentieri Dennis C | Local vascular delivery of PI3 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury |
| US20070203564A1 (en) * | 2006-02-28 | 2007-08-30 | Boston Scientific Scimed, Inc. | Biodegradable implants having accelerated biodegradation properties in vivo |
| US9492596B2 (en) | 2006-11-06 | 2016-11-15 | Atrium Medical Corporation | Barrier layer with underlying medical device and one or more reinforcing support structures |
| US8142490B2 (en) | 2007-10-24 | 2012-03-27 | Cordis Corporation | Stent segments axially connected by thin film |
| US8728528B2 (en) | 2007-12-20 | 2014-05-20 | Evonik Corporation | Process for preparing microparticles having a low residual solvent volume |
| US20110038910A1 (en) | 2009-08-11 | 2011-02-17 | Atrium Medical Corporation | Anti-infective antimicrobial-containing biomaterials |
| US20110301695A1 (en) * | 2010-06-08 | 2011-12-08 | Svelte Medical Systems, Inc. | Optimum coatings for vascular stents |
| EP2582408B1 (en) | 2010-06-21 | 2014-09-10 | Zorion Medical, Inc. | Bioabsorbable implants |
| WO2012009707A2 (en) | 2010-07-16 | 2012-01-19 | Atrium Medical Corporation | Composition and methods for altering the rate of hydrolysis of cured oil-based materials |
| US9867880B2 (en) | 2012-06-13 | 2018-01-16 | Atrium Medical Corporation | Cured oil-hydrogel biomaterial compositions for controlled drug delivery |
| EP2968730B1 (en) | 2013-03-15 | 2019-01-09 | Bitol Designs, LLC | Occlusion resistant catheter and method of use |
| CA2998170C (en) | 2015-09-15 | 2023-10-03 | Savage Medical, Inc. | Devices and methods for anchoring a sheath in a tissue cavity |
| JP7108631B2 (ja) | 2017-01-06 | 2022-07-28 | パルヴェラ セラピューティクス、インク． | ｍＴＯＲ阻害剤の無水組成物およびその使用方法 |
| CN107335100A (zh) * | 2017-07-31 | 2017-11-10 | 首都医科大学附属北京安贞医院 | 一种冠状动脉旁路移植术预防桥血管再狭窄系统 |
| JP2021530463A (ja) | 2018-07-02 | 2021-11-11 | パルヴェラ セラピューティクス、インク． | ｍＴＯＲ阻害剤の無水組成物および使用方法 |
| WO2022271702A1 (en) * | 2021-06-21 | 2022-12-29 | Palvella Therapeutics, Inc. | Methods and compositions for treating gorlin syndrome |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA737247B (en) * | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
| US3959078A (en) * | 1973-05-18 | 1976-05-25 | Midwest Research Institute | Enzyme immobilization with a thermochemical-photochemical bifunctional agent |
| SU1088712A1 (ru) * | 1979-11-14 | 1984-04-30 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Аппарат дл циркул рного сшивани кровеносных сосудов |
| US4368736A (en) | 1980-11-17 | 1983-01-18 | Kaster Robert L | Anastomotic fitting |
| US4366819A (en) * | 1980-11-17 | 1983-01-04 | Kaster Robert L | Anastomotic fitting |
| US4917091A (en) * | 1982-06-24 | 1990-04-17 | Unilink Ab | Annular fastening means |
| SE431609B (sv) | 1982-06-24 | 1984-02-20 | Unilink Ab | Kirurgiskt instrument for astadkommande av anastomos och festelement herfor |
| US4722906A (en) * | 1982-09-29 | 1988-02-02 | Bio-Metric Systems, Inc. | Binding reagents and methods |
| US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
| US5234447A (en) * | 1990-08-28 | 1993-08-10 | Robert L. Kaster | Side-to-end vascular anastomotic staple apparatus |
| US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
| US5350800A (en) * | 1993-01-19 | 1994-09-27 | Medtronic, Inc. | Method for improving the biocompatibility of solid surfaces |
| US5308641A (en) * | 1993-01-19 | 1994-05-03 | Medtronic, Inc. | Biocompatibility of solid surfaces |
| US5229172A (en) * | 1993-01-19 | 1993-07-20 | Medtronic, Inc. | Modification of polymeric surface by graft polymerization |
| US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US5837313A (en) * | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
| US6120536A (en) * | 1995-04-19 | 2000-09-19 | Schneider (Usa) Inc. | Medical devices with long term non-thrombogenic coatings |
| US7611533B2 (en) * | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| WO1998033443A1 (en) | 1997-02-03 | 1998-08-06 | Angioguard, Inc. | Vascular filter |
| US6425898B1 (en) * | 1998-03-13 | 2002-07-30 | Cordis Corporation | Delivery apparatus for a self-expanding stent |
| US8029561B1 (en) | 2000-05-12 | 2011-10-04 | Cordis Corporation | Drug combination useful for prevention of restenosis |
| US6153252A (en) * | 1998-06-30 | 2000-11-28 | Ethicon, Inc. | Process for coating stents |
| CA2340652C (en) * | 1998-08-20 | 2013-09-24 | Cook Incorporated | Coated implantable medical device comprising paclitaxel |
| AU780539B2 (en) | 2000-02-25 | 2005-03-24 | Cordis Corporation | Use of cladribine on a stent to prevent restenosis |
| US7419678B2 (en) * | 2000-05-12 | 2008-09-02 | Cordis Corporation | Coated medical devices for the prevention and treatment of vascular disease |
| AU1129902A (en) * | 2000-09-29 | 2002-04-08 | Cordis Corp | Coated medical devices |
| US7195640B2 (en) * | 2001-09-25 | 2007-03-27 | Cordis Corporation | Coated medical devices for the treatment of vulnerable plaque |
| US8652502B2 (en) * | 2003-12-19 | 2014-02-18 | Cordis Corporation | Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury |
| US7306677B2 (en) * | 2004-01-30 | 2007-12-11 | Boston Scientific Corporation | Clamping fixture for coating stents, system using the fixture, and method of using the fixture |
-
2004
- 2004-02-18 US US10/780,596 patent/US7806924B2/en active Active
-
2005
- 2005-02-16 CA CA2497216A patent/CA2497216C/en not_active Expired - Lifetime
- 2005-02-17 JP JP2005040910A patent/JP4846246B2/ja not_active Expired - Fee Related
- 2005-02-17 AT AT05250908T patent/ATE442169T1/de not_active IP Right Cessation
- 2005-02-17 DE DE602005016479T patent/DE602005016479D1/de not_active Expired - Lifetime
- 2005-02-17 EP EP05250908A patent/EP1570871B1/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8986369B2 (en) | 2010-12-01 | 2015-03-24 | Zorion Medical, Inc. | Magnesium-based absorbable implants |
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