JP2005211184A - Eyedropper and adapter for applying minute amount of liquid medication - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To solve a problem that a conventional eyedropper applies 30-150 μL of liquid medication excessive for the eye and the liquid medication overflown from the eye inside causes dermatitis around the eye. <P>SOLUTION: This eyedropper is provided with a nozzle with a caliber of 0.1-0.8 mm enabling to apply the liquid medication of 30 μL or less, which is the amount preventing the liquid overflow from the eye. This adapter is attached to the nozzle part of the conventional eyedropper and enables to apply the liquid medication of 30 μL or less. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

The present invention is an eye drop container that allows an eye drop of 30 μl (microliter) or less, which is an amount of eye drop that does not overflow from the eye, or a small amount that does not overflow from the eye when attached to an existing eye drop container. An adapter capable of dripping the ophthalmic solution is provided.

In the case of dropping ophthalmic solution into the eye, when an amount of liquid of 30 μl or less is dropped, it can be stored in the eye without overflowing from the eye. However, when instillation is performed using an existing ophthalmic solution container, a liquid amount of about 30 to 150 μl is dropped during one instillation. Since the maximum retention volume of the conjunctival sac is about 30 μl, a liquid volume of 30 to 150 μl is excessive for the eye. For this reason, the drug solution often overflows from the eye when dropped, causing periocular dermatitis. To solve the problem of periocular dermatitis, develop an eye drop container that can drop a small amount of drug solution of 30 μl or less, which is the amount of drug solution that can be stored in the eye, or attach it to an existing eye drop container to make 30 μl There is a demand for an adapter that can drop the following amount of chemical solution.
Kanji Takada, effective people who are effective, Shueisha, 2000

When an eye drop is instilled using the current eye drop container, about 30 to 150 μl of the liquid amount is dropped at the time of one drop, so that an excessive amount of the drug solution is dropped. At the time of dripping, the solution often overflows from within the eye, and there are problems that cause side effects such as inflammation and injury to the skin around the eye.

Since it is known that the amount of medicinal solution that can be stored in the eye by instillation per time is 30 μl or less, an eye drop container that can drop a small amount of medicinal solution of 30 μl or less per instillation, Alternatively, the present invention has been completed by devising an adapter that can be attached to an existing eye drop container and can drop a small amount of drug solution of 30 μl or less.

If you use an eye drop container with a 0.1-0.8mm narrow inner diameter nozzle or an adapter with a pore diameter of 0.1-0.8mm that can be attached to the nozzle of a conventional eye drop container, a small amount of eye drop of 30μl or less is dropped. It becomes possible to do.

As a result of intensive studies in order to solve the above problems, the present inventors have invented an eye drop container having a nozzle with a narrow inner diameter and a pore adapter used by attaching to an existing eye drop container. FIG. 1 shows a nozzle portion for an eye drop container having a pore that enables a small amount of dripping, which has been developed as a result of the present invention. The tip of the eye drop container is designed to be thinner than the inner diameter of the nozzle of the conventional eye drop container. As a result of the experiment, by setting the inner diameter to about 0.5 mm, it was possible to drop a small amount of eye drops of 30 μl or less. FIGS. 2 and 3 show examples of adapters that are attached to a conventional eye drop container to reduce the amount of the dropped drug solution to an amount of 30 μl or less. Any material can be a plastic such as polyethylene or polypropylene conventionally used for eye drops. In addition, this invention is not limited to FIGS. 1-3, FIGS. 1-3 is only clarified as an example in the case of implementing this invention, respectively.

Ophthalmic container in which the inner diameter of the pores through which the chemical solution passes in the nozzle portion of the ophthalmic bottle is 0.1 to 0.8 mm

Example of an adapter with an inner diameter of 0.1 to 0.8 mm to be inserted into the nozzle part of an existing eye drop container

Example of an adapter having an inner diameter of about 0.5 mm to be inserted into the nozzle part of an existing eye drop container

When an eye drop is instilled using the current eye drop container, about 30 to 150 μl of the liquid amount is dropped at the time of one drop, so that an excessive amount of drug solution is dropped. When dropped, the liquid often overflows from the eye, causing side effects such as inflammation and injury to the skin around the eye. By using the eye drop container according to the present invention or attaching the adapter of the present invention to a conventional eye drop container, the above-mentioned problems can be solved by instilling a small amount of liquid that does not overflow from the eye. .

An eye drop container that can drop a small amount of eye drops that do not overflow from the eye, or an adapter that can be attached to an existing eye drop container and allow a minute amount of eye drops that do not overflow from the eye to drop. By using it, it is possible to instill a small amount of a drug solution of 30 μl or less that does not overflow from the eye.

Example Nozzle portion for eye drop container having an inner diameter of about 0.5 mm designed to drop a small amount of drug solution according to the present invention (Example 1) Example of adapter used by attaching to the nozzle portion of an existing eye drop container designed to drop a small amount of drug solution according to the present invention and its sectional view (Example 2) Example of adapter used by attaching to the nozzle portion of an existing eye drop container designed to drop a small amount of drug solution according to the present invention and its cross-sectional view (Example 3)

Claims (3)

After instillation, an eye drop container with a fine inner diameter of 0.1 to 0.8 mm that can drop a liquid volume of 30 μl (microliter) or less, which is a liquid volume that does not overflow from within the eye, or 30 μl or less attached to a conventional eye drop container An adapter having 0.1 to 0.8 mm pores that allows the amount of ophthalmic solution to be dropped. An ophthalmic container nozzle having an inner diameter of 0.1 to 0.8 mm to which a drug solution amount of 30 μl or less, which is a drug solution amount that does not overflow from within the eye after instillation, can be dropped. An adapter that can be attached to a conventional eye dropper container to drop a drug solution of 30 μl or less.