JP2005041976A - Polyester resin injection molding for medical device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide polyester resin injection moldings for medical devices which exhibit few effluents, contain no endocrine disrupters, has good injection-moldability, transparency and color, and exhibit little discoloration due to sterilization processing by radiation or electron beam irradiation. <P>SOLUTION: A copolymerized polyester resin composition comprises at least 60-95 mol% of terephthalic acid and 5-40 mol% of isophthalic acid as a dicarboxylic acid component and 65-100 mol% of ethylene glycol as a glycol component, wherein it contains 5-300 ppm as an element of one or more elements selected from Ge and Al, and has an intrinsic viscosity of 0.50-0.90 dl/g and a melting point of 180-245°C. The polyester resin injection moldings for medical devices can be obtained by injection-molding the copolymerized polyester resin composition and has the following properties: (1) a haze per a thickness of 4 mm of 1.0 or less; (2) a water-elution volume at 50°C for 5 hours of 3 ppm or less; and (3) a yellowness index (YI) of 8.0 or less. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

【００３４】
表中の略号は次の通りである。原料モノマーはすべてナカライテスク社のＧＲ試薬を使用した。
ＰＴＡ：テレフタル酸
ＩＰＡ：イソフタル酸
ＮＤＣ：ナフタレンジカルボン酸
ＥＧ：エチレングリコール
Ｇｅ：ゲルマニューム
Ａｌ：アルミニューム
Ｃｏ：コバルト
Ｓｂ：アンチモン
Ｓｔ−Ｍｇ：ステアリン酸マグネシューム
【００３５】
【発明の効果】
本発明の共重合ポリエステル樹脂組成物からなる成形体は、透明性と色調に優れており、かつ放射線や電子線照射による光学特性の変化が少なく、医療用具のケースやコックに最適である。特に、放射線や電子線照射による滅菌処理による基材樹脂の変質による光学特性の低下の少ないので、医療用用具が放射線あるいは電子線照射により滅菌処理される用途により好適に用いることができる。[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an injection molded body for a medical device. More specifically, the present invention relates to an injection molded body for a medical device that is highly transparent, good in color tone, and high in safety. The present invention relates to a copolyester resin injection-molded article suitable for a human body that does not contain an environmental hormone substance and is suitable for cases such as cases, caps, cocks, and piping of medical devices. In particular, the present invention relates to a copolyester resin injection-molded article suitable for a container for storing a dialysis membrane of a blood purifier, which is sterilized by radiation or electron beam irradiation.
[0002]
[Prior art]
As materials for drip and artificial dialysis devices, hard vinyl chloride resins and polycarbonate resins have been widely used because of their excellent injection moldability, transparency, and mechanical properties. However, in recent years, there are concerns about the adverse effects of phthalic acid esters and bisphenols contained in hard vinyl chloride resins and polycarbonate resins on the human body, and therefore, development of resin compositions to replace them has been demanded. As a container for medical equipment, it goes without saying that it does not have an adverse effect on the human body, and high transparency and good color tone are required to confirm the state of the contents.
[0003]
In addition, although substitution with polyethylene terephthalate resin has been attempted in part, the transparency of the gate part and thick part at the time of molding is lost, and only a molded product with high yellowness can be obtained, so the color tone of the contents There was a problem with confirmation. Further, although it is an effective means to use a low-temperature mold for imparting transparency, there is also a problem that a good mold cannot be obtained due to insufficient fluidity.
[0004]
In addition, in recent years, it has been desired that the medical device container is economically excellent, and as a molding method thereof, an injection molding method with high production efficiency has been developed. Since the injection moldability is inferior, the improvement has been desired.
[0005]
Japanese Patent Laid-Open Nos. 2000-297144 and 2003-40987 have already disclosed polyester resin injection-molded bodies using specific copolymerized polyesters. However, the molded body obtained by the above method does not satisfy the market demand in terms of transparency and color tone as a container for a medical device. Further, in recent years, as a method for sterilizing a container of a medical device from the viewpoint of safety and economy, a method of irradiating radiation or an electron beam has been increasing, but the sterilization treatment causes deterioration of the container material of the medical device, Countermeasures are required because the color tone and transparency deteriorate, but the molded product obtained by the above method is not designed for alteration due to radiation or electron beam irradiation during the sterilization treatment. It is inferior in characteristics and does not meet market requirements.
[0006]
[Patent Document 1]
JP 2000-297144 A [Patent Document 2]
JP 2003-40987 A
[Problems to be solved by the invention]
The present invention provides a molded article for a medical device that has less elution, does not contain an environmental hormonal substance, has good injection moldability, and can ensure the state of the contents in the molded article. An object of the present invention is to provide an injection molded article for a medical device that has a good color tone and is less susceptible to discoloration due to sterilization treatment by radiation or electron beam irradiation.
[0008]
[Means for Solving the Problems]
In order to solve the above-mentioned problems, the present inventors have intensively studied and finally completed the present invention. That is, the present invention contains 10 to 300 ppm of one or more elements selected from germanium elements and aluminum elements as elements, 60 to 95 mol% of terephthalic acid as at least a dicarboxylic acid component, and 5 to 5 of isophthalic acid. A copolymer polyester resin composition comprising 40 mol% and 65 to 100 mol% of ethylene glycol as a glycol component, having an intrinsic viscosity of 0.50 to 0.90 dl / g and a melting point of 180 to 245 ° C. is injected. An injection-molded article obtained by molding, wherein the molded article has the following properties (1) to (3): a polyester-based resin injection-molded article for medical devices.
(1) The haze per 4 mm thickness is 1.0 or less.
(2) The amount of water elution at 50 ° C. for 5 hours is 3 ppm or less.
(3) Yellowness index (YI) is 8.0 or less.
[0009]
The resin composition for a medical device of the present invention having the above-described structure has little eluate, does not contain an environmental hormonal substance, has high fluidity, is excellent in injection moldability, is transparent and has a good color tone, and is a radiation or electron beam. It is possible to provide a polyester-based resin injection molded article for a medical device in which the state of the contents of the molded article can be observed with little change in optical characteristics due to irradiation.
[0010]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, embodiments of the resin composition for medical devices of the present invention will be described.
It is important that the copolymerized polyester resin composition used in the present invention contains 5 to 300 ppm of one or more elements selected from germanium elements and aluminum elements. 10-250 ppm is preferable and 15-200 ppm is especially preferable. These are used as polymerization catalysts. These elements are preferably added as oxides, acetates, alkoxides and the like. If these elements are 5 ppm or less, the polymerization rate is low and the productivity is low, and if they are 300 ppm or more, the thermal decomposition at the time of melt molding is promoted, the color tone is yellowish, and the effect of the present invention cannot be exhibited. In addition, it is not possible to suppress a decrease in optical characteristics due to sterilization treatment by radiation or electron beam irradiation.
[0011]
In the present invention, as described in claim 2, it is a preferred embodiment that the copolymerized polyester resin composition contains 1 to 30 ppm of cobalt element. By the blending, a bluing effect is exhibited, YI described later is reduced, and the color tone of the molded body is improved. 2-20 ppm is preferable and 3-10 ppmm is particularly preferable. If it is less than 1 ppm, the effect of improving the color tone is small. Conversely, if it exceeds 30 ppm, the transparency and lightness of the molded product are lowered, which is not preferable. The cobalt element is preferably added as an oxide, acetate, alkoxide or the like. In the present invention, it is a preferred embodiment to use 0.5 to 2 equivalents of phosphorus element in combination with the cobalt element. By using the phosphorus element in combination, the bluing effect can be efficiently expressed.
The phosphorus element is preferably added and added as phosphoric acid, phosphorous acid, hypophosphorous acid, and ester compounds thereof.
[0012]
The copolymerized polyester resin composition used in the present invention contains at least 60 to 95 mol% of terephthalic acid as a dicarboxylic acid component, 5 to 40 mol% of isophthalic acid, and 65 to 100 mol% of ethylene glycol as a glycol component. It is important that By using the copolyester resin having such a composition, the injection moldability can be ensured, and both the transparency and heat resistance of the molded product can be achieved. As acid components other than terephthalic acid and isophthalic acid, known acid components can be copolymerized. For example, naphthalenedicarboxylic acid, cyclohexanedicarboxylic acid, adipic acid, sebacic acid and the like are used. Among these, naphthalenedicarboxylic acid is preferable because the decrease in heat resistance is small. Examples of glycol components other than ethylene glycol include 1,3 propylene glycol, 1,4 butanediol, neopentyl glycol, cyclohexane dimethanol, diethylene glycol, polyethylene glycol, polytetramethylene glycol, polylactone, and the like. Among these, butanediol and neopentyl glycol are preferable from the viewpoint of transparency of the molded product.
[0013]
In order to obtain a molded article having transparency and good color tone from the copolymer polyester resin composition, the copolymer polyester resin composition has an intrinsic viscosity (according to JIS K7390, solvent: phenol / tetrachloroethane = 6/4 mass ratio, measurement). (Temperature: 30 ° C.) is preferably 0.50 to 0.90 dl / g. In particular, 0.55 to 0.85 dl / g is preferable. When the intrinsic viscosity is 0.50 or less, even if a water-cooled mold is used, if the molded body is thick, the inside is gradually cooled during molding and the copolymerized polyester resin composition is crystallized and whitened. On the other hand, if it is 0.90 dl / g or more, stress-induced crystallization occurs near the gate where a high shear force is applied during injection molding, and the transparency of the molded product is lowered, which is not preferable.
[0014]
Moreover, 180-245 degreeC is preferable and, as for melting | fusing point of the said copolyester resin composition, the range of 200-235 degreeC is more preferable. When the melting point is 245 ° C. or higher, the molded body is whitened due to the spherulite structure that is expressed by crystallization of the copolyester resin, transparency is easily impaired, and the molding condition width is narrow and the mass productivity is poor. The copolymer polyester resin having a melting point of 180 to 245 ° C. can crystallize the raw material pellets before injection molding, and therefore has an advantage that pre-drying can be performed at a high temperature in a short time, and trouble caused by fusion of the raw material pellets at the time of injection molding. Is preferable. If the melting point is within this range, the obtained injection-molded product having a high transparency can be obtained even though the crystal state is white and devitrified before molding. Therefore, it is possible to achieve both the workability of being able to handle at a high temperature and the product performance of being able to obtain a highly transparent molded body. Note that the melting point here is an endothermic peak temperature associated with crystal melting at a temperature rising rate of 20 ° C./min in a differential scanning calorimeter (DSC).
[0015]
The polyester-based resin injection molded article for a medical device of the present invention is calculated by the equation (1) from the tristimulus values (ASTM D1925) measured with a color difference meter. It is important that the yellowness index (YI) is 8.0 or less.
YI = 100 (1.28X-1.06Z) / Y (1)
YI is more preferably 6.0 or less. YI is a measure of yellowness, and the smaller the value, the lower the yellowness. When it exceeds 8.0, for example, when used as a container, the color tone of the contents looks different, which is not preferable. It is one of the important characteristics as a container for medical equipment.
[0016]
It is important that the polyester-based resin injection molded article for a medical device of the present invention has a haze per 4 mm thickness of 1.0% or less, preferably 0.9% or less, particularly 0.8% or less. preferable. When it exceeds 1.0%, for example, when used as a container, the transparency of the contents deteriorates, which is not preferable. Similar to the above characteristics, it is one of the important characteristics as a container for medical equipment.
[0017]
The polyester resin injection molded article for medical devices of the present invention needs to have a water elution amount of 3 ppm or less at 50 ° C. for 5 hours, preferably 2.5 ppm or less. 2 ppm or less is particularly preferable. This water elution amount is determined as follows. 50 g of 3 mmφ × 3 mm long pellets are weighed and packed in a glass U-tube, and 700 ml of water at 50 ° C. is circulated at a circulation rate of 300 ml / min for 5 hours. After 20 ml of the circulated liquid is placed in a weighing bottle and evaporated to dryness at 105 ° C., the mass of the evaporation residue is weighed, and the fraction relative to the sample pellet is evaluated in ppm. If the amount of water is more than this, it affects the contents of the medical device and is inappropriate. The water eluate contains monomers, oligomer residues, stabilizers and catalysts.
The method for bringing the water elution amount within the range of the present invention can be achieved by using a highly pure monomer and selecting a water-insoluble stabilizer.
A method of removing monomers and oligomers before molding is also a preferred embodiment. Examples of the removal method include a method of extracting with a solvent, a method of extracting in a supercritical pressure state, and a method of heating and scattering under reduced pressure.
[0018]
In the case of a medical device, it is necessary to observe not only the drip solution or the dialysate but also the state of foreign matter, transparency and color tone. The transparency and color tone of the container and the cock are important performances related to the success or failure of the medical device.
[0019]
Furthermore, you may add a usual additive, for example, a heat-resistant stabilizer, a glaze-proofing agent, a hydrolysis-resistant agent, a pigment, etc. to the copolyester resin composition used for this invention. Examples of the heat stabilizer include hindered phenols, thioethers, phosphites, and combinations thereof. Examples of the antifungal agent include benzophenone, triazole, and hindered amine. Examples of the hydrolysis resistance agent include carbodiimide, bisoxazoline, epoxy, and isocyanate compounds. Moreover, a fluorescent dye can also be mix | blended.
[0020]
The copolymerized polyester resin composition used in the present invention can be polymerized by mixing the above-described constituent components at the monomer stage. In addition, the stabilizer and the release agent can be mixed before and after the polymerization, but they are produced by kneading the release agent and the stabilizer using an apparatus such as a single screw extruder, a twin screw extruder or a kneader. be able to. A composition containing a stabilizer in a higher concentration can be previously melt-kneaded and mixed as a master batch at the time of molding.
Moreover, as a method of injection-molding the copolyester resin composition obtained by the above method into an injection-molded body, it is preferable that the mold temperature is 20 to 60 ° C. as described in claim 3. . In particular, the range of 25 to 55 ° C is preferable. A lower mold temperature is preferable because crystallization of the molded body is suppressed and transparency of the molded body is improved. However, molding at less than 20 ° C. causes condensation when the humidity of the molding environment is high. It becomes easy. Moreover, since temperature control is difficult, it is not preferable. Furthermore, at the time of injection molding, the distortion may be uneven due to the front and back sides and portions of the molded body, which may cause cracks, which is not preferable. On the other hand, when the temperature is 60 ° C. or higher, the mold release resistance increases and the haze of the molded product increases, which is not preferable.
[0021]
In the present invention, since the copolymer polyester resin is optimized to the above-described composition, stable production can be performed in the mold temperature range. However, as described in claim 4, the copolymer polyester resin composition is separated. It is a preferred embodiment that the mold contains 0.01 to 2% by mass. As a mold release agent, the mold release resistance must be reduced without devitrifying the copolyester resin. Examples include higher fatty acid esters, higher fatty acid salts, higher fatty acid monoamides, and higher fatty acid bisamides. In particular, higher fatty acid salts having 20 or less carbon atoms and bisamides of higher fatty acids are preferred. These release agents are blended in an amount of 0 to 2 parts by mass, preferably 0.01 to 0.8 parts by mass with respect to 100 parts by mass of the polyester resin. If it exceeds 2 parts by mass, the transparency and color tone of the molded article are impaired, which is not preferable for the present invention. By mix | blending this mold release agent, the mold release property of the molded object from a metal mold | die improves, and the stability of production improves more.
[0022]
As described in claim 4, the polyester resin injection molded article for medical devices according to the present invention has an increase in color difference value (Y value) of 8.0 when the above-mentioned injection molded article is irradiated with 20 kGy of γ-rays. The following is a preferred embodiment. 7.0 or less is preferable, and 6.0 or less is particularly preferable. By satisfying this characteristic, it can be suitably used as a medical device that is sterilized by irradiation with the aforementioned radiation or electron beam. This characteristic can be achieved by setting the polyester resin composition in the above-described range.
[0023]
The use of the polyester-based resin injection molded article for a medical device of the present invention is not particularly limited, but since it has the above-described properties, it is used for a medical device in which the medical device is sterilized by radiation or electron beam irradiation as described in claim 5. It is a preferred embodiment that Moreover, it is a preferable embodiment that the polyester-based resin injection molded article for a medical device of the present invention is used as a container for housing a dialysis membrane of a blood purifier for the same reason. By developing for these applications, the characteristics of the polyester resin injection molded article for medical devices of the present invention can be expressed more effectively.
[0024]
【Example】
The present invention will be specifically described below with reference to examples. The physical properties in the specification were measured by the following methods.
(1) Intrinsic viscosity of copolymerized polyester resin It was dissolved in a mixed solvent of phenol / tetrachloroethane = 6/4 (mass ratio) according to JIS K7390 and measured at 30 ° C. using an Ubbelohde viscometer. In addition, the measurement was performed 3 times and the average value was calculated | required.
(2) Melting point of copolymerized polyester resin A copolymerized polyester resin crystallized from DuPont, V4.0B2000, using differential scanning calorimetry, in an argon atmosphere, sample weight: 10 mg, temperature rising start temperature: 30 ° C. The temperature increase rate was measured at 20 ° C./min, and the endothermic peak temperature was determined as the melting point.
(3) Copolymerization polyester resin copolymer composition 1 mg of copolymer polyester resin was subjected to proton NMR measurement under the following conditions.
(Measurement condition)
Apparatus: Nuclear magnetic resonance apparatus (AVANCE500 manufactured by BRUKER)
Measurement solvent: deuterated chloroform / trifluoroacetic acid = 9/1 (v / v)
¹ H resonance frequency: 500 MHz
Number of integrations: 512 times Measurement temperature: Room temperature [0025]
(4) Quantitative determination of metal content of copolymerized polyester resin Measured by fluorescent X-ray method. It quantified with the analytical curve calculated | required using the standard sample with known content about each metal. (Measurement device: Rigaku Electric's top-illuminated X-ray fluorescence analyzer ZSX 100e)
(5) Preparation of test piece After the pellets of the copolymerized polyester resin composition were dried at 120 ° C for 5 hours, a release agent was added to the pellets, and the injection molding machine adjusted to a cylinder temperature of 240-260-260 ° C. Using a mold whose surface temperature was adjusted to 30 ° C. by supplying it to the hopper, 100 mm by a film gate having a thickness of 1 mm and a land length of 1 mm under conditions of an injection time of 10 seconds and a cooling time of 10 seconds. A flat plate of × 100 × 4 mm was injection molded. These flat plates were used as samples for evaluation.
[0026]
(6) Yellowness index (YI)
Using a color difference meter (TC1500MC-88 manufactured by Tokyo Denshoku Industries Co., Ltd.) and a C light source, tristimulus values XYZ values according to ASTM D1925 for the central part of the 4 mm thick flat plate produced in (5) Was measured. The yellowness index (YI) was calculated according to the following formula.
YI = 100 (1.28X-1.06Z) / Y (1)
[0027]
(7) Transparency (haze)
About the central part of the 4 mm thick flat plate produced in (5), according to JIS K7361-1, using Nippon Denshoku Industries Co., Ltd. turbidimeter (Haze Meter NDH2000 type) and a halogen lamp, haze It was measured.
(8) Water-eluting property 50 g of 3 mmφ × 3 mm long pellets were weighed and packed in a glass U-tube, and 700 ml of 50 ° C. distilled water was circulated at a circulation rate of 300 ml / min for 5 hours. The circulated liquid was placed in a 20 ml weighing bottle and evaporated to dryness at 105 ° C. The mass of the evaporation residue was weighed and evaluated at a fractional ppm relative to the sample pellet mass.
(9) The 4 mm thick flat plate produced in radiation resistance (5) was placed in a light-shielded and oxygen-free state, irradiated with 20 kGy of γ rays, and the change in yellowness index before and after irradiation (ΔYI) was evaluated. YI was evaluated by the method shown in (6).
[0028]
(Example 1)
90 mol parts of terephthalic acid, 10 mol parts of isophthalic acid and 159 mol parts of ethylene glycol were placed in a reaction vessel equipped with a rectifying column and a stirrer, and the temperature was gradually raised to 260 ° C. while stirring. Esterification is carried out while discharging the distilled water out of the system, and after transferring to a polycondensation reactor, the reaction is held at 260 ° C. for 15 minutes. Then, oxidized germanium is used as a polycondensation catalyst, and 80 ppm as a germanium element with respect to the produced polyester It added so that it might become. After 5 minutes, cobalt acetate and trimethyl phosphate as a color tone improver were added as cobalt element and phosphorus element to 5 ppm and 10 ppm, respectively, and after 5 minutes, the degree of vacuum was −90 kPa or less, 280 ° C. Was copolymerized for 2 hours to obtain a copolyester. This was vacuum-dried and crystallized at 140 ° C. for 6 hours at a vacuum degree of −90 kPa, subsequently heated to 200 ° C. and subjected to solid-phase polymerization for 6 hours, and a copolymer polyester resin having the copolymer composition shown in Table 1 was obtained. Got. A test piece was produced from the obtained copolyester resin under the conditions described above. Table 1 shows the characteristic values of the obtained test pieces.
[0029]
(Comparative Example 1)
In the method of Example 1, the copolymerized polyester resin and test piece of this comparative example were prepared in the same manner as in Example 1 except that the polycondensation catalyst was antimony trioxide and the addition of the color adjusting agents cobalt and phosphorus compound was stopped. Obtained. Table 1 shows the characteristic values of the obtained test pieces.
[0030]
(Comparative Examples 2 and 3)
A polyester resin and test pieces of these comparative examples were obtained in the same manner as in Comparative Example 1 except that the polyester resin composition was changed as shown in Table 1 by the method of Comparative Example 1. Table 1 shows the characteristic values of the obtained test pieces. In Comparative Example 2, copolymerization was stopped and polyethylene terephthalate was used.
[0031]
(Examples 2 to 4)
A copolymer polyester resin and a test piece of this comparative example were obtained in the same manner as in Example 1 except that the copolymer polyester composition, polycondensation catalyst and color tone modifier composition were changed as shown in Table 1 in the method of Example 1. It was. Table 1 shows the characteristic values of the obtained test pieces.
[0032]
All of the injection-molded articles obtained in Examples 1 to 4 are excellent in transparency, color tone, elution amount, and radiation resistance, and can be suitably used for medical devices. On the other hand, Comparative Example 1 has poor color tone and radiation resistance, Comparative Example 2 has poor color tone, transparency, elution amount, and radiation resistance durability, and Comparative Example 3 has poor color tone, elution amount, and radiation resistance durability. The quality was low for medical devices.
[0033]
[Table 1]

[0034]
Abbreviations in the table are as follows. All raw material monomers used were GR reagents from Nacalai Tesque.
PTA: terephthalic acid IPA: isophthalic acid NDC: naphthalene dicarboxylic acid EG: ethylene glycol Ge: germanium Al: aluminum Co: cobalt Sb: antimony St-Mg: magnesium stearate
【The invention's effect】
The molded body made of the copolymerized polyester resin composition of the present invention is excellent in transparency and color tone, has little change in optical properties due to radiation or electron beam irradiation, and is optimal for cases and cocks of medical devices. In particular, since there is little deterioration in optical properties due to alteration of the base resin due to sterilization treatment by radiation or electron beam irradiation, the medical device can be suitably used for applications in which sterilization treatment is performed by radiation or electron beam irradiation.

Claims (7)

Contains at least one element selected from germanium element and aluminum element in an amount of 5 to 300 ppm, at least 60 to 95 mol% of terephthalic acid, 5 to 40 mol% of isophthalic acid, and glycol as a dicarboxylic acid component Injection obtained by injection molding a copolymer polyester resin composition comprising 65 to 100 mol% of ethylene glycol as an ingredient, having an intrinsic viscosity of 0.50 to 0.90 dl / g and a melting point of 180 to 245 ° C. A polyester-based resin injection molded article for a medical device, which is a molded article, wherein the molded article has the following properties (1) to (3).
(1) The haze per 4 mm thickness is 1.0 or less.
(2) The amount of water elution at 50 ° C. for 5 hours is 3 ppm or less.
(3) Yellowness index (YI) is 8.0 or less. The polyester resin injection molded article for medical devices according to claim 1, wherein the copolymerized polyester resin composition contains 1 to 30 ppm of cobalt element. 3. The polyester resin injection molded article for medical devices according to claim 1, wherein a mold temperature at the time of injection molding is 20 to 60 ° C. 3. The polyester resin injection molded article for medical devices according to any one of claims 1 to 3, wherein the copolymerized polyester resin composition contains 0.01 to 2% by mass of a release agent. The polyester-based resin for a medical device according to any one of claims 1 to 4, wherein an increase in yellowness index (YI) when the injection molded product is irradiated with γ-rays of 20 kGy is 8.0 or less. Injection molded body. The polyester-based resin injection molded article for a medical device according to any one of claims 1 to 5, wherein the medical device is used for a sterilization treatment by radiation or electron beam irradiation. The polyester-based resin injection molded article for a medical device according to any one of claims 1 to 6, wherein the medical device is a container for storing a dialysis membrane of a blood purifier.