JP2005015460A5 - - Google Patents

Info

Publication number

JP2005015460A5

JP2005015460A5 JP2003366734A JP2003366734A JP2005015460A5 JP 2005015460 A5 JP2005015460 A5 JP 2005015460A5 JP 2003366734 A JP2003366734 A JP 2003366734A JP 2003366734 A JP2003366734 A JP 2003366734A JP 2005015460 A5 JP2005015460 A5 JP 2005015460A5

Authority

JP

Japan

Prior art keywords

sglt

seq

glucose transporter

salt

agent

Prior art date

2003-10-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 102000018711 Facilitative Glucose Transport Proteins Human genes 0.000 claims 20
• 108091052347 Glucose transporter family Proteins 0.000 claims 20
• 102000000070 Sodium-Glucose Transport Proteins Human genes 0.000 claims 20
• 108010080361 Sodium-Glucose Transport Proteins Proteins 0.000 claims 20
• 239000003795 chemical substances by application Substances 0.000 claims 16
• 150000003839 salts Chemical class 0.000 claims 14
• 125000003275 alpha amino acid group Chemical group 0.000 claims 12
• 230000004190 glucose uptake Effects 0.000 claims 10
• 210000000813 small intestine Anatomy 0.000 claims 10
• 150000001875 compounds Chemical class 0.000 claims 8
• 108090000623 proteins and genes Proteins 0.000 claims 8
• 239000002157 polynucleotide Substances 0.000 claims 7
• 102000040430 polynucleotide Human genes 0.000 claims 7
• 108091033319 polynucleotide Proteins 0.000 claims 7
• 238000012216 screening Methods 0.000 claims 7
• 230000000694 effects Effects 0.000 claims 6
• 108090000765 processed proteins & peptides Proteins 0.000 claims 6
• 102000004169 proteins and genes Human genes 0.000 claims 6
• 201000001421 hyperglycemia Diseases 0.000 claims 5
• 238000000034 method Methods 0.000 claims 5
• 239000003112 inhibitor Substances 0.000 claims 4
• 239000002773 nucleotide Substances 0.000 claims 4
• 125000003729 nucleotide group Chemical group 0.000 claims 4
• 208000031226 Hyperlipidaemia Diseases 0.000 claims 3
• 208000008589 Obesity Diseases 0.000 claims 3
• 206010012601 diabetes mellitus Diseases 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 235000020824 obesity Nutrition 0.000 claims 3
• 229940124597 therapeutic agent Drugs 0.000 claims 3
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 239000000032 diagnostic agent Substances 0.000 claims 2
• 229940039227 diagnostic agent Drugs 0.000 claims 2
• 230000003449 preventive effect Effects 0.000 claims 2
• WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
• 229940124532 absorption promoter Drugs 0.000 claims 1
• 230000000692 anti-sense effect Effects 0.000 claims 1
• 239000008103 glucose Substances 0.000 claims 1
• 230000000069 prophylactic effect Effects 0.000 claims 1