JP2004537275A - Ｄ−アミノ酸オキシダーゼおよびｄ−アスパラギン酸オキシダーゼのアンタゴニストを使用するｃｎｓ障害の処置 - Google Patents

Ｄ−アミノ酸オキシダーゼおよびｄ−アスパラギン酸オキシダーゼのアンタゴニストを使用するｃｎｓ障害の処置 Download PDF

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JP2004537275A
JP2004537275A JP2002566376A JP2002566376A JP2004537275A JP 2004537275 A JP2004537275 A JP 2004537275A JP 2002566376 A JP2002566376 A JP 2002566376A JP 2002566376 A JP2002566376 A JP 2002566376A JP 2004537275 A JP2004537275 A JP 2004537275A
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polypeptide
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コーヘン、ダニエル
イリヤ チュマコブ
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ジェンセット
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    • A—HUMAN NECESSITIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/30—Psychoses; Psychiatry
    • G01N2800/302—Schizophrenia

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  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
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  • Physics & Mathematics (AREA)
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  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
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JP2002566376A 2001-01-16 2002-01-15 Ｄ−アミノ酸オキシダーゼおよびｄ−アスパラギン酸オキシダーゼのアンタゴニストを使用するｃｎｓ障害の処置 Pending JP2004537275A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26188301P 2001-01-16 2001-01-16
US30544501P 2001-07-13 2001-07-13
US34521101P 2001-10-22 2001-10-22
US33388101P 2001-11-19 2001-11-19
PCT/IB2002/001262 WO2002066672A2 (en) 2001-01-16 2002-01-15 Treatment of cns disorders using d-amino acid oxidase and d-aspartate oxidase antagonists

Publications (2)

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JP2004537275A true JP2004537275A (ja) 2004-12-16
JP2004537275A5 JP2004537275A5 (pt) 2006-01-05

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JP2002566376A Pending JP2004537275A (ja) 2001-01-16 2002-01-15 Ｄ−アミノ酸オキシダーゼおよびｄ−アスパラギン酸オキシダーゼのアンタゴニストを使用するｃｎｓ障害の処置

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EP (1) EP1412515A2 (pt)
JP (1) JP2004537275A (pt)
KR (1) KR20030066813A (pt)
CN (1) CN1568370A (pt)
AU (1) AU2002247939B2 (pt)
BR (1) BR0206495A (pt)
CA (1) CA2433866A1 (pt)
EA (1) EA006654B1 (pt)
IL (1) IL156865A0 (pt)
MX (1) MXPA03006321A (pt)
WO (1) WO2002066672A2 (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009522377A (ja) * 2006-01-09 2009-06-11 オクラホマ メディカル リサーチ ファウンデーション 炎症性疾患治療のためのランチオニン関連化合物
JP4462382B1 (ja) * 2009-04-23 2010-05-12 学校法人北里研究所 Ｄ−アスパラギン酸オキシダーゼおよびｄ−アミノ酸オキシダーゼに対する新規阻害剤
JP2012515720A (ja) * 2009-01-20 2012-07-12 ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー− ユーシーエルエー メディカル センター 向精神薬の働きを向上させるソルビン酸、安息香酸及びその誘導体

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE408593T1 (de) 2001-05-03 2008-10-15 Galileo Lab Inc Pyruvatderivate
EP1291015A1 (en) 2001-09-10 2003-03-12 Lunamed AG Dosage forms having prolonged active ingredient release
WO2003039540A2 (en) * 2001-11-09 2003-05-15 Sepracor Inc. D-amino acid oxidase inhibitors for learning and memory
WO2003047558A2 (en) * 2001-12-03 2003-06-12 Genset S.A. Treatment of cns disorders using d-amino acid oxidase and d-aspartate oxidase inhibitors
US20060234221A1 (en) * 2001-12-12 2006-10-19 Genset S.A. Biallelic markers of d-amino acid oxidase and uses thereof
EP1495041A4 (en) * 2002-02-20 2006-02-01 Sirna Therapeutics Inc RNA interferon-mediated inhibition of gene expression of G72 and D-amino acid oxidase (DAAO) using short-term interfering nucleic acid (siNA)
GB0223424D0 (en) * 2002-10-09 2002-11-13 Imp College Innovations Ltd Disease-associated gene
BRPI0418244A (pt) 2003-12-29 2007-04-17 Sepracor Inc composto, métodos para aumentar a concentração de d-serina e/ou diminuir a concentração de produtos tóxicos da oxidação de d-serina pela daao em um mamìfero, para tratar a esquizofrenia, para tratar ou prevenir a perda de memória e/ou cognição associadas com o mal de alzheimer, para tratar a ataxia ou para prevenir a perda da função neuronal caracterìstica de doenças neurodegenerativas, para intensificar a aprendizagem, memória e/ou cognição e para tratar dor neuropática, e, composição farmacêutica
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
GB2456390A (en) * 2008-01-15 2009-07-22 Glaxo Group Ltd Bipolar disorder treatments
WO2012135119A1 (en) * 2011-03-25 2012-10-04 Genomind, Llc Biomarker-based detection and treatment of neurodegenerative depression
EP2831232A4 (en) 2012-03-30 2015-11-04 Univ Washington METHODS OF MODULATING THE EXPRESSION OF TAU TO REDUCE THE STROKE AND MODIFY A NEURODEGENERATIVE SYMPTOM
RU2765625C2 (ru) 2016-06-13 2022-02-01 Сайньюрекс Интернэшнл (Тайвань) Корп. Сокристаллы бензоата лития и их применения
EP3468944B1 (en) 2016-06-13 2022-11-16 Syneurx International (Taiwan) Corp. Co-crystals of sodium benzoate and uses thereof
US10336679B2 (en) 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof
CN108504752B (zh) * 2018-06-26 2021-05-11 华中农业大学 一种与母猪繁殖性状关联的分子标记及应用
CN111909907B (zh) * 2020-07-08 2022-05-24 浙江工业大学 天冬氨酸氧化酶突变体、工程菌及其在氧化-还原偶联制备精草铵膦中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
CA2361408A1 (en) * 1999-03-30 2000-10-05 Genset S.A. Schizophrenia associated genes, proteins and biallelic markers
AU6462500A (en) * 1999-07-29 2001-02-19 Patrick T. Prendergast Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement
WO2001068104A1 (en) * 2000-03-16 2001-09-20 The Mclean Hospital Corporation Compounds for the treatment of psychiatric or substance abuse disorders

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009522377A (ja) * 2006-01-09 2009-06-11 オクラホマ メディカル リサーチ ファウンデーション 炎症性疾患治療のためのランチオニン関連化合物
JP2012515720A (ja) * 2009-01-20 2012-07-12 ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー− ユーシーエルエー メディカル センター 向精神薬の働きを向上させるソルビン酸、安息香酸及びその誘導体
JP4462382B1 (ja) * 2009-04-23 2010-05-12 学校法人北里研究所 Ｄ−アスパラギン酸オキシダーゼおよびｄ−アミノ酸オキシダーゼに対する新規阻害剤
JP2010254609A (ja) * 2009-04-23 2010-11-11 Kitasato Institute Ｄ−アスパラギン酸オキシダーゼおよびｄ−アミノ酸オキシダーゼに対する新規阻害剤

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AU2002247939B2 (en) 2007-01-25
MXPA03006321A (es) 2003-10-06
BR0206495A (pt) 2006-01-24
CN1568370A (zh) 2005-01-19
WO2002066672A3 (en) 2004-02-26
IL156865A0 (en) 2004-02-08
CA2433866A1 (en) 2002-08-29
KR20030066813A (ko) 2003-08-09
EA200300807A1 (ru) 2004-08-26
EA006654B1 (ru) 2006-02-24
AU2002247939B9 (en) 2002-09-04
EP1412515A2 (en) 2004-04-28
WO2002066672A2 (en) 2002-08-29

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