JP2004536847A - 眼の疾患の処置のためのチューブリン結合薬剤を投与するための組成物および方法 - Google Patents
眼の疾患の処置のためのチューブリン結合薬剤を投与するための組成物および方法 Download PDFInfo
- Publication number
- JP2004536847A JP2004536847A JP2003511808A JP2003511808A JP2004536847A JP 2004536847 A JP2004536847 A JP 2004536847A JP 2003511808 A JP2003511808 A JP 2003511808A JP 2003511808 A JP2003511808 A JP 2003511808A JP 2004536847 A JP2004536847 A JP 2004536847A
- Authority
- JP
- Japan
- Prior art keywords
- eye
- combretastatin
- subject
- administered
- ocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38622701P | 2001-07-13 | 2001-07-13 | |
| US37755602P | 2002-05-03 | 2002-05-03 | |
| US37784502P | 2002-05-03 | 2002-05-03 | |
| US37784702P | 2002-05-03 | 2002-05-03 | |
| PCT/US2002/022449 WO2003006002A1 (en) | 2001-07-13 | 2002-07-15 | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009063664A Division JP2009132738A (ja) | 2001-07-13 | 2009-03-16 | 眼の疾患の処置のためのチューブリン結合薬剤を投与するための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004536847A true JP2004536847A (ja) | 2004-12-09 |
| JP2004536847A5 JP2004536847A5 (enExample) | 2006-01-05 |
Family
ID=32034390
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003511808A Pending JP2004536847A (ja) | 2001-07-13 | 2002-07-15 | 眼の疾患の処置のためのチューブリン結合薬剤を投与するための組成物および方法 |
| JP2009063664A Pending JP2009132738A (ja) | 2001-07-13 | 2009-03-16 | 眼の疾患の処置のためのチューブリン結合薬剤を投与するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009063664A Pending JP2009132738A (ja) | 2001-07-13 | 2009-03-16 | 眼の疾患の処置のためのチューブリン結合薬剤を投与するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1406600A4 (enExample) |
| JP (2) | JP2004536847A (enExample) |
| KR (1) | KR20040030042A (enExample) |
| CN (1) | CN1527704B (enExample) |
| CA (1) | CA2453442C (enExample) |
| NZ (1) | NZ575466A (enExample) |
| WO (1) | WO2003006002A1 (enExample) |
| ZA (1) | ZA200400210B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012532113A (ja) * | 2009-07-02 | 2012-12-13 | オキシジーン, インコーポレイテッド | 後嚢混濁を予防するためのコンブレタスタチン |
| JP2013502440A (ja) * | 2009-08-27 | 2013-01-24 | バイオノミックス リミテッド | 黄斑変性の治療 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040229960A1 (en) * | 2001-07-13 | 2004-11-18 | David Sherris | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
| JP4005048B2 (ja) * | 2003-04-09 | 2007-11-07 | 日信工業株式会社 | 炭素繊維複合材料およびその製造方法 |
| NZ598489A (en) | 2009-08-27 | 2014-03-28 | Bionomics Ltd | Combination therapy for treating proliferative diseases |
| CN104619760B (zh) * | 2012-08-02 | 2016-10-26 | 阿米利尔股份公司 | 含纳米碳的天然橡胶 |
| CN113577020B (zh) * | 2021-08-16 | 2022-09-23 | 海南鑫开源医药科技有限公司 | 一种玻璃体腔内注射剂、其制备方法及应用 |
| CN113520995B (zh) * | 2021-08-16 | 2023-03-10 | 海南鑫开源医药科技有限公司 | 一种离子敏感型眼用原位凝胶、其制备方法及应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63233939A (ja) * | 1987-01-06 | 1988-09-29 | アリゾナ ボード オブ リーゼンツ | コンブレタスタチン類 |
| WO1999035150A1 (en) * | 1998-01-09 | 1999-07-15 | Arizona Board Of Regents, A Body Corporate, Acting On Behalf Of Arizona State University | Synthesis of combretastatin a-4 prodrugs and trans-isomers thereo f |
| WO2000048591A1 (en) * | 1999-02-16 | 2000-08-24 | Angiogene Pharmaceuticals Ltd. | Combinations for the treatment of diseases involving angiogenesis |
| WO2000048606A1 (en) * | 1999-02-18 | 2000-08-24 | Oxigene, Inc. | Compositions and methods for use in targeting vascular destruction |
| WO2002022626A1 (en) * | 2000-09-14 | 2002-03-21 | Bristol-Myers Squibb Company | Combretastatin a-4 phosphate prodrug salts with nitrogen-containing compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5504074A (en) * | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
-
2002
- 2002-07-15 JP JP2003511808A patent/JP2004536847A/ja active Pending
- 2002-07-15 EP EP02756487A patent/EP1406600A4/en not_active Withdrawn
- 2002-07-15 NZ NZ575466A patent/NZ575466A/en not_active IP Right Cessation
- 2002-07-15 CN CN028139917A patent/CN1527704B/zh not_active Expired - Fee Related
- 2002-07-15 KR KR10-2004-7000464A patent/KR20040030042A/ko not_active Ceased
- 2002-07-15 CA CA2453442A patent/CA2453442C/en not_active Expired - Fee Related
- 2002-07-15 WO PCT/US2002/022449 patent/WO2003006002A1/en not_active Ceased
-
2004
- 2004-01-12 ZA ZA2004/00210A patent/ZA200400210B/en unknown
-
2009
- 2009-03-16 JP JP2009063664A patent/JP2009132738A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63233939A (ja) * | 1987-01-06 | 1988-09-29 | アリゾナ ボード オブ リーゼンツ | コンブレタスタチン類 |
| WO1999035150A1 (en) * | 1998-01-09 | 1999-07-15 | Arizona Board Of Regents, A Body Corporate, Acting On Behalf Of Arizona State University | Synthesis of combretastatin a-4 prodrugs and trans-isomers thereo f |
| WO2000048591A1 (en) * | 1999-02-16 | 2000-08-24 | Angiogene Pharmaceuticals Ltd. | Combinations for the treatment of diseases involving angiogenesis |
| WO2000048606A1 (en) * | 1999-02-18 | 2000-08-24 | Oxigene, Inc. | Compositions and methods for use in targeting vascular destruction |
| WO2002022626A1 (en) * | 2000-09-14 | 2002-03-21 | Bristol-Myers Squibb Company | Combretastatin a-4 phosphate prodrug salts with nitrogen-containing compounds |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012532113A (ja) * | 2009-07-02 | 2012-12-13 | オキシジーン, インコーポレイテッド | 後嚢混濁を予防するためのコンブレタスタチン |
| JP2013502440A (ja) * | 2009-08-27 | 2013-01-24 | バイオノミックス リミテッド | 黄斑変性の治療 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1406600A1 (en) | 2004-04-14 |
| NZ575466A (en) | 2011-01-28 |
| CN1527704A (zh) | 2004-09-08 |
| WO2003006002A8 (en) | 2004-05-27 |
| WO2003006002A1 (en) | 2003-01-23 |
| EP1406600A4 (en) | 2007-06-06 |
| JP2009132738A (ja) | 2009-06-18 |
| CN1527704B (zh) | 2011-05-18 |
| KR20040030042A (ko) | 2004-04-08 |
| WO2003006002A9 (en) | 2004-07-22 |
| CA2453442C (en) | 2011-02-01 |
| CA2453442A1 (en) | 2003-01-23 |
| ZA200400210B (en) | 2005-06-29 |
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