JP2004536783A5 - - Google Patents
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- Publication number
- JP2004536783A5 JP2004536783A5 JP2002552127A JP2002552127A JP2004536783A5 JP 2004536783 A5 JP2004536783 A5 JP 2004536783A5 JP 2002552127 A JP2002552127 A JP 2002552127A JP 2002552127 A JP2002552127 A JP 2002552127A JP 2004536783 A5 JP2004536783 A5 JP 2004536783A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- immune response
- sequence
- signal
- sequence homology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 21
- 230000028993 immune response Effects 0.000 claims 6
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 claims 2
- 125000005647 linker group Chemical group 0.000 claims 2
- 230000004044 response Effects 0.000 claims 2
- 230000029069 type 2 immune response Effects 0.000 claims 2
- QUBNFZFTFXTLKH-UHFFFAOYSA-N 2-aminododecanoic acid Chemical compound CCCCCCCCCCC(N)C(O)=O QUBNFZFTFXTLKH-UHFFFAOYSA-N 0.000 claims 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- 108700018351 Major Histocompatibility Complex Proteins 0.000 claims 1
- 108091008874 T cell receptors Proteins 0.000 claims 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 229960002684 aminocaproic acid Drugs 0.000 claims 1
- 229940000635 beta-alanine Drugs 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- PBLZLIFKVPJDCO-UHFFFAOYSA-N omega-Aminododecanoic acid Natural products NCCCCCCCCCCCC(O)=O PBLZLIFKVPJDCO-UHFFFAOYSA-N 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/739,466 US7786257B2 (en) | 2000-12-18 | 2000-12-18 | Signal-1/signal-2 bifunctional peptide inhibitors |
| PCT/US2001/048632 WO2002050250A2 (en) | 2000-12-18 | 2001-12-17 | Signal-1/signal-2 bifunctional peptide inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004536783A JP2004536783A (ja) | 2004-12-09 |
| JP2004536783A5 true JP2004536783A5 (cg-RX-API-DMAC7.html) | 2005-06-09 |
Family
ID=24972431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002552127A Pending JP2004536783A (ja) | 2000-12-18 | 2001-12-17 | シグナル−１／シグナル−２二官能性ペプチド阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7786257B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1932539A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2004536783A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE400293T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002230911A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2432767A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60134791D1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002050250A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8188218B2 (en) | 2006-10-27 | 2012-05-29 | University Of Kansas | Bi-functional peptides for multiple sclerosis treatment and diagnosis |
| US8735154B2 (en) | 2006-10-30 | 2014-05-27 | The University Of Kansas | Templated islet cells and small islet cell clusters for diabetes treatment |
| WO2008067281A1 (en) * | 2006-11-30 | 2008-06-05 | Vance Products Incorporated D/B/A Cook Urological Incorporated | Removable handle for medical device |
| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| WO2009022155A2 (en) * | 2007-08-15 | 2009-02-19 | Circassia Limited | Peptide with reduced dimer formation |
| AU2008317331B2 (en) * | 2007-10-25 | 2013-08-29 | The Scripps Research Institute | Antibody-mediated disruption of quorum sensing in bacteria |
| DE102009040716B4 (de) * | 2009-09-10 | 2011-07-14 | Miltenyi Biotec GmbH, 51429 | Verwendung von CD154 zur Identifizierung und Abtrennung von nicht-regulatorischen T-Zellen aus einem Gemisch mit regulatorischen T-Zellen |
| EP2585096B1 (en) | 2010-06-24 | 2021-05-05 | University Of Kansas | Bifunctional conjugate compositions and associated methods |
| EP2736536A4 (en) | 2011-07-27 | 2015-03-11 | Univ Kansas | TEMPLATE ISLAND CELLS AND SMALL ISLAND CELL PATTERNS FOR THE TREATMENT OF DIABETES |
| JP6126107B2 (ja) * | 2011-10-18 | 2017-05-10 | 株式会社アモーレパシフィックＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ | シリンガレシノールを含むｓｉｒｔ−１活性化剤 |
| WO2018215506A1 (en) * | 2017-05-23 | 2018-11-29 | Université De Genève | Beta-2-glycoprotein 1 derived peptide and use thereof for treating antiphospholipid syndrome |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5844095A (en) * | 1991-06-27 | 1998-12-01 | Bristol-Myers Squibb Company | CTLA4 Ig fusion proteins |
| EP0576842B1 (de) * | 1992-06-11 | 2002-10-16 | MERCK PATENT GmbH | Verfahren und Mittel zum Nachweis von Listerien |
| US5540926A (en) * | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
| JP4382163B2 (ja) | 1997-03-27 | 2009-12-09 | ザ カウンシル オブ ザ クイーンズランド インスティチュート オブ メディカル リサーチ | ターゲッティング分子を用いた免疫応答の増強 |
| AU1084901A (en) * | 1999-10-14 | 2001-04-23 | Martha S. Hayden-Ledbetter | Dna vaccines encoding antigen linked to a domain that binds cd40 |
-
2000
- 2000-12-18 US US09/739,466 patent/US7786257B2/en not_active Expired - Fee Related
-
2001
- 2001-12-17 DE DE60134791T patent/DE60134791D1/de not_active Expired - Fee Related
- 2001-12-17 EP EP07014573A patent/EP1932539A3/en not_active Withdrawn
- 2001-12-17 CA CA002432767A patent/CA2432767A1/en not_active Abandoned
- 2001-12-17 AU AU2002230911A patent/AU2002230911A1/en not_active Abandoned
- 2001-12-17 JP JP2002552127A patent/JP2004536783A/ja active Pending
- 2001-12-17 WO PCT/US2001/048632 patent/WO2002050250A2/en not_active Ceased
- 2001-12-17 AT AT01991168T patent/ATE400293T1/de not_active IP Right Cessation
- 2001-12-17 EP EP01991168A patent/EP1404362B1/en not_active Expired - Lifetime
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