JP2004535397A - 心細胞におけるカルシウムチャンネルの活性の調節法及びそのための試薬 - Google Patents
心細胞におけるカルシウムチャンネルの活性の調節法及びそのための試薬 Download PDFInfo
- Publication number
- JP2004535397A JP2004535397A JP2002589036A JP2002589036A JP2004535397A JP 2004535397 A JP2004535397 A JP 2004535397A JP 2002589036 A JP2002589036 A JP 2002589036A JP 2002589036 A JP2002589036 A JP 2002589036A JP 2004535397 A JP2004535397 A JP 2004535397A
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- JP
- Japan
- Prior art keywords
- peptide
- channel
- cardiac
- activity
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9453—Cardioregulators, e.g. antihypotensives, antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR5066A AUPR506601A0 (en) | 2001-05-17 | 2001-05-17 | Method of modulating the activity of calcium channels in cardiac cells and reagents therefor |
| PCT/AU2002/000608 WO2002092119A1 (en) | 2001-05-17 | 2002-05-17 | Method of modulating the activity of calcium channels in cardiac cells and reagents therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004535397A true JP2004535397A (ja) | 2004-11-25 |
| JP2004535397A5 JP2004535397A5 (enExample) | 2006-01-05 |
Family
ID=3829046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002589036A Withdrawn JP2004535397A (ja) | 2001-05-17 | 2002-05-17 | 心細胞におけるカルシウムチャンネルの活性の調節法及びそのための試薬 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050049198A1 (enExample) |
| EP (1) | EP1392344A4 (enExample) |
| JP (1) | JP2004535397A (enExample) |
| KR (1) | KR20040002970A (enExample) |
| CN (1) | CN1516596A (enExample) |
| AU (1) | AUPR506601A0 (enExample) |
| BR (1) | BR0210902A (enExample) |
| CA (1) | CA2446839A1 (enExample) |
| NZ (1) | NZ529940A (enExample) |
| WO (1) | WO2002092119A1 (enExample) |
| ZA (1) | ZA200309727B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011174707A (ja) * | 2010-02-23 | 2011-09-08 | Kanazawa Univ | 心筋障害の検査方法 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101812523B (zh) * | 2010-04-09 | 2012-08-22 | 广州益善生物技术有限公司 | Ryr1基因snp检测特异性引物、液相芯片和检测方法 |
| CN109010799B (zh) * | 2018-07-09 | 2021-07-06 | 沣潮医药科技(上海)有限公司 | RyR2蛋白或RyR2重组蛋白在制备抗心力衰竭药物中的用途 |
| CN109306011B (zh) * | 2018-09-27 | 2021-08-03 | 中国人民解放军第二军医大学 | 靶向RyR2蛋白的胞内纳米抗体在制备抗心力衰竭药物中的用途 |
| CN119876003B (zh) * | 2025-01-21 | 2026-04-24 | 深圳大学 | 一种肌质网钙泵囊泡的分离纯化方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5691310A (en) * | 1987-09-29 | 1997-11-25 | Vesely; David L. | Methods of treatment using proANF peptides |
| DE4110785A1 (de) * | 1991-04-04 | 1992-10-08 | Bayer Ag | Gewebe-spezifische humane neuronale calcium-kanal-subtypen und deren verwendung |
| AU1890092A (en) * | 1991-04-18 | 1992-11-17 | Indiana University Foundation | Novel ester derivatives of ryanodine and dehydroryanodine |
| EP1218407A4 (en) * | 1999-09-22 | 2003-01-08 | Cognetix Inc | USES OF KAPPA-CONOTOXIN PVIIA |
| GB0005124D0 (en) * | 2000-03-03 | 2000-04-26 | Cellpep Sa | Maurocalcin,analogues thereof and their therapeutical uses |
| US7105489B2 (en) * | 2002-01-22 | 2006-09-12 | Amylin Pharmaceuticals, Inc. | Methods and compositions for treating polycystic ovary syndrome |
-
2001
- 2001-05-17 AU AUPR5066A patent/AUPR506601A0/en not_active Abandoned
-
2002
- 2002-05-17 US US10/478,112 patent/US20050049198A1/en not_active Abandoned
- 2002-05-17 NZ NZ529940A patent/NZ529940A/en unknown
- 2002-05-17 BR BR0210902-6A patent/BR0210902A/pt not_active IP Right Cessation
- 2002-05-17 EP EP02721869A patent/EP1392344A4/en not_active Withdrawn
- 2002-05-17 JP JP2002589036A patent/JP2004535397A/ja not_active Withdrawn
- 2002-05-17 CN CNA028120566A patent/CN1516596A/zh active Pending
- 2002-05-17 WO PCT/AU2002/000608 patent/WO2002092119A1/en not_active Ceased
- 2002-05-17 CA CA002446839A patent/CA2446839A1/en not_active Abandoned
- 2002-05-17 KR KR10-2003-7014989A patent/KR20040002970A/ko not_active Withdrawn
-
2003
- 2003-12-15 ZA ZA200309727A patent/ZA200309727B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011174707A (ja) * | 2010-02-23 | 2011-09-08 | Kanazawa Univ | 心筋障害の検査方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1516596A (zh) | 2004-07-28 |
| CA2446839A1 (en) | 2002-11-21 |
| US20050049198A1 (en) | 2005-03-03 |
| AUPR506601A0 (en) | 2001-06-07 |
| NZ529940A (en) | 2006-08-31 |
| EP1392344A1 (en) | 2004-03-03 |
| BR0210902A (pt) | 2004-06-08 |
| EP1392344A4 (en) | 2005-09-21 |
| WO2002092119A1 (en) | 2002-11-21 |
| KR20040002970A (ko) | 2004-01-07 |
| ZA200309727B (en) | 2005-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050517 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050517 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20070621 |