JP2004527476A5 - - Google Patents

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Publication number
JP2004527476A5
JP2004527476A5 JP2002560615A JP2002560615A JP2004527476A5 JP 2004527476 A5 JP2004527476 A5 JP 2004527476A5 JP 2002560615 A JP2002560615 A JP 2002560615A JP 2002560615 A JP2002560615 A JP 2002560615A JP 2004527476 A5 JP2004527476 A5 JP 2004527476A5
Authority
JP
Japan
Prior art keywords
diabetes
vardenafil
solvate
pharmaceutically acceptable
insulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2002560615A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004527476A (ja
Filing date
Publication date
Priority claimed from GB0106468A external-priority patent/GB0106468D0/en
Application filed filed Critical
Priority claimed from PCT/IB2002/000315 external-priority patent/WO2002060422A2/en
Publication of JP2004527476A publication Critical patent/JP2004527476A/ja
Publication of JP2004527476A5 publication Critical patent/JP2004527476A5/ja
Withdrawn legal-status Critical Current

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JP2002560615A 2001-02-02 2002-01-30 真性糖尿病の処置 Withdrawn JP2004527476A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26608301P 2001-02-02 2001-02-02
GB0106468A GB0106468D0 (en) 2001-03-15 2001-03-15 Treatment of diabetes mellitus
PCT/IB2002/000315 WO2002060422A2 (en) 2001-02-02 2002-01-30 Treatment of diabetes mellitus using vardenafil

Publications (2)

Publication Number Publication Date
JP2004527476A JP2004527476A (ja) 2004-09-09
JP2004527476A5 true JP2004527476A5 (https=) 2005-06-09

Family

ID=26245830

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002560615A Withdrawn JP2004527476A (ja) 2001-02-02 2002-01-30 真性糖尿病の処置

Country Status (8)

Country Link
US (1) US6683080B2 (https=)
EP (1) EP1355651A2 (https=)
JP (1) JP2004527476A (https=)
AU (1) AU2002226633A1 (https=)
BR (1) BR0206847A (https=)
CA (1) CA2436576A1 (https=)
MX (1) MXPA03006936A (https=)
WO (1) WO2002060422A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020165237A1 (en) * 2000-08-11 2002-11-07 Fryburg David Albert Treatment of the insulin resistance syndrome
DE10135815A1 (de) * 2001-07-23 2003-02-06 Bayer Ag Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen
US20030114469A1 (en) * 2001-09-27 2003-06-19 Cohen David Saul Combinations
JP2005508978A (ja) * 2001-11-02 2005-04-07 ファイザー・プロダクツ・インク Pde9阻害薬によるインスリン抵抗性症候群及び2型糖尿病の治療
US20030181461A1 (en) * 2002-01-25 2003-09-25 Lautt Wilfred Wayne Use of phosphodiesterase antagonists to treat insulin resistance
US20040077650A1 (en) * 2002-10-18 2004-04-22 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
BRPI0408500A (pt) * 2003-03-17 2006-03-07 Pfizer Prod Inc tratamento do diabetes do tipo 1 com inibidores de pde5
DE10325813B4 (de) * 2003-06-06 2007-12-20 Universitätsklinikum Freiburg Prophylaxe und/oder Therapie bei der portalen Hypertonie
DE102004023069A1 (de) * 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
WO2006074443A2 (en) * 2005-01-07 2006-07-13 The Johns Hopkins University Pde5 inhibitor compositions and methods for immunotherapy
US20060235005A1 (en) * 2005-04-14 2006-10-19 Oak Labs, Corp. Use of phosphodiesterase 5 (PDE5) inhibitors in the treatment of schizophrenia
DE102005018389A1 (de) * 2005-04-20 2006-10-26 Sanofi-Aventis Deutschland Gmbh Azolderivate als Inhibitoren von Lipasen und Phospholipasen
WO2007010337A2 (de) * 2005-07-15 2007-01-25 Proxomed Medizintechnik Gmbh Verwendung von phosphodiesterase typ 5-hemmern für die prävention und behandlung von adipositas, sowie abgabesysteme für dieselben
WO2008028914A1 (en) 2006-09-07 2008-03-13 Nycomed Gmbh Combination treatment for diabetes mellitus
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) * 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
KR101560844B1 (ko) 2007-06-04 2015-10-15 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 트라이-아릴계 화합물 및 이를 포함하는 조성물
ES2522968T3 (es) * 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20100221329A1 (en) 2008-12-03 2010-09-02 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase c agonists and methods of use
US8592370B2 (en) * 2008-12-12 2013-11-26 Poxel S.A.S. Combination of insulin with triazine derivatives
JP2013508295A (ja) 2009-10-16 2013-03-07 デューク・ユニヴァーシティ 薬物誘発性手足症候群を治療するための組成物および方法
US8637096B2 (en) 2009-12-04 2014-01-28 Curtis C. Stojan Compositions and method for enhancing insulin activity
WO2011162320A1 (ja) * 2010-06-23 2011-12-29 国立大学法人九州大学 Egcgまたはメチル化egcgとpde阻害剤との組み合わせ
WO2012037380A2 (en) 2010-09-15 2012-03-22 Synergy Pharmaceuticals Inc. Formulations of guanylate cyclase c agonists and methods of use
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AT512084A1 (de) 2011-10-20 2013-05-15 Univ Wien Tech Diazabicyclo- und diazaspiro-alkanderivate als phosphodiesterase-5 inhibitoren
WO2013106547A1 (en) * 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
MX2016005995A (es) 2013-11-05 2016-08-17 Ben-Gurion Univ Of The Negev Res And Dev Authority Compuestos para el tratamiento de diabetes y complicaciones de la enfermedad derivadas de la misma.
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2395558C (en) 1997-11-12 2007-07-17 Bayer Aktiengesellschaft Intermediates for 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
KR20010052235A (ko) * 1998-04-06 2001-06-25 후지야마 아키라 인돌 유도체
DE19944161A1 (de) 1999-09-15 2001-03-22 Bayer Ag Neue Kombination zur Behandlung von sexueller Dysfunktion
ATE257480T1 (de) * 1999-09-30 2004-01-15 Pfizer Prod Inc Bicyclische pyrrolylamide als glycogenphosphorylase-inhibitoren
AU2001219185A1 (en) 2000-03-17 2001-10-03 Alcon, Inc. 2-acylaminobenzimidazole derivatives for treating glaucoma
US6774128B2 (en) 2000-04-19 2004-08-10 Johns Hopkins University Methods for prevention and treatment of gastrointestinal disorders
WO2001088824A2 (en) 2000-05-15 2001-11-22 Imakit, Ltd. Method and system for online custom footwear preparation
AU2001276607A1 (en) * 2000-08-11 2002-02-25 Pfizer Inc. Treatment of the insulin resistance syndrome with selective CGMP PDE5 inhibitors

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