JP2004524511A - アフィニティ捕捉タンデム質量分析のための装置および方法 - Google Patents

アフィニティ捕捉タンデム質量分析のための装置および方法 Download PDF

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Publication number
JP2004524511A
JP2004524511A JP2002534826A JP2002534826A JP2004524511A JP 2004524511 A JP2004524511 A JP 2004524511A JP 2002534826 A JP2002534826 A JP 2002534826A JP 2002534826 A JP2002534826 A JP 2002534826A JP 2004524511 A JP2004524511 A JP 2004524511A
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JP
Japan
Prior art keywords
probe
laser
protein
analytical instrument
affinity capture
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Pending
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JP2002534826A
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English (en)
Japanese (ja)
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JP2004524511A5 (enExample
Inventor
ワインバーガー,スコット
エンス,ワーナー
ラボダ,アレクサンダー
スパイサー,ヴィクター
ブライアン,レイモンド,ジー.
スタンディング,ケン
トールネーター,ピート
マクナッブ,ジェームス,アール.
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シファーゲン バイオシステムズ, インコーポレイテッド
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Publication of JP2004524511A publication Critical patent/JP2004524511A/ja
Publication of JP2004524511A5 publication Critical patent/JP2004524511A5/ja
Pending legal-status Critical Current

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    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]

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  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Plasma & Fusion (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electron Tubes For Measurement (AREA)
JP2002534826A 2000-10-11 2000-10-11 アフィニティ捕捉タンデム質量分析のための装置および方法 Pending JP2004524511A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/028163 WO2002031491A2 (en) 2000-10-11 2000-10-11 Apparatus and methods for affinity capture tandem mass spectrometry

Publications (2)

Publication Number Publication Date
JP2004524511A true JP2004524511A (ja) 2004-08-12
JP2004524511A5 JP2004524511A5 (enExample) 2005-04-14

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Family Applications (1)

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JP2002534826A Pending JP2004524511A (ja) 2000-10-11 2000-10-11 アフィニティ捕捉タンデム質量分析のための装置および方法

Country Status (8)

Country Link
EP (1) EP1327256A2 (enExample)
JP (1) JP2004524511A (enExample)
KR (1) KR20040010541A (enExample)
CN (1) CN1502116A (enExample)
AU (1) AU2001210807A1 (enExample)
CA (1) CA2425456A1 (enExample)
IL (1) IL154932A0 (enExample)
WO (1) WO2002031491A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005024551A (ja) * 2003-06-10 2005-01-27 Santen Pharmaceut Co Ltd シェーグレン症候群患者の検定方法
JP2006329896A (ja) * 2005-05-30 2006-12-07 Hitachi High-Technologies Corp 質量分析方法及び質量分析装置
JP2015105951A (ja) * 2013-11-28 2015-06-08 コリア ベーシック サイエンス インスティテュートKorea Basic Science Institute 血液由来の癌診断用ペプチドマーカー及びそれを用いた癌診断方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10125258A1 (de) 2001-05-23 2003-01-09 November Ag Molekulare Medizin Verfahren zur Bestimmung des Bindeverhaltens von an Ziel-Molekülen spezifisch bindenden Liganden
GB2384778A (en) * 2001-12-21 2003-08-06 Sense Proteomic Ltd Probe for mass spectrometry
US7064319B2 (en) * 2003-03-31 2006-06-20 Hitachi High-Technologies Corporation Mass spectrometer
GB0404106D0 (en) * 2004-02-24 2004-03-31 Shimadzu Res Lab Europe Ltd An ion trap and a method for dissociating ions in an ion trap
KR100805775B1 (ko) * 2005-08-08 2008-02-21 한국기초과학지원연구원 변형된 폴리펩티드(Modifiedpolypeptide)의 서열 및 변형 정보를 분석하는방법
CN106055895B (zh) * 2010-09-15 2021-02-19 Dh科技发展私人贸易有限公司 产物离子谱的数据独立获取及参考谱库匹配
EP2850645B1 (en) * 2012-05-18 2018-10-31 DH Technologies Development Pte. Ltd. Systems and methods for using interleaving window widths in tandem mass spectrometry
CN113049663B (zh) * 2021-01-27 2023-10-20 中国科学院成都生物研究所 一维线材样品转储及质谱分析的装置和使用方法
CN115184530B (zh) * 2022-08-19 2023-11-24 北京中医药大学 一种多级在线能量分辨质谱法及其在结构精准鉴定中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498545A (en) * 1994-07-21 1996-03-12 Vestal; Marvin L. Mass spectrometer system and method for matrix-assisted laser desorption measurements

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005024551A (ja) * 2003-06-10 2005-01-27 Santen Pharmaceut Co Ltd シェーグレン症候群患者の検定方法
JP2006329896A (ja) * 2005-05-30 2006-12-07 Hitachi High-Technologies Corp 質量分析方法及び質量分析装置
JP2015105951A (ja) * 2013-11-28 2015-06-08 コリア ベーシック サイエンス インスティテュートKorea Basic Science Institute 血液由来の癌診断用ペプチドマーカー及びそれを用いた癌診断方法

Also Published As

Publication number Publication date
CN1502116A (zh) 2004-06-02
WO2002031491A3 (en) 2003-01-09
AU2001210807A1 (en) 2002-04-22
CA2425456A1 (en) 2002-04-18
EP1327256A2 (en) 2003-07-16
WO2002031491A2 (en) 2002-04-18
KR20040010541A (ko) 2004-01-31
IL154932A0 (en) 2003-10-31

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