CN1502116A - 亲和捕获串联质谱分析设备和方法 - Google Patents

亲和捕获串联质谱分析设备和方法 Download PDF

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Publication number
CN1502116A
CN1502116A CNA008199590A CN00819959A CN1502116A CN 1502116 A CN1502116 A CN 1502116A CN A008199590 A CNA008199590 A CN A008199590A CN 00819959 A CN00819959 A CN 00819959A CN 1502116 A CN1502116 A CN 1502116A
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CN
China
Prior art keywords
probe
analytical device
protein
laser
affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA008199590A
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English (en)
Chinese (zh)
Inventor
ʷ���ء��²���
史高特·温伯格
沃纳·安斯
亚历山大·拉博达
维克托·斯派塞
G
雷蒙德·G·布赖恩
肯·史旦丁
比德·托纳托
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspira Womens Health Inc
Original Assignee
Ciphergen Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciphergen Biosystems Inc filed Critical Ciphergen Biosystems Inc
Publication of CN1502116A publication Critical patent/CN1502116A/zh
Pending legal-status Critical Current

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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]

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  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Plasma & Fusion (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electron Tubes For Measurement (AREA)
CNA008199590A 2000-10-11 2000-10-11 亲和捕获串联质谱分析设备和方法 Pending CN1502116A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/028163 WO2002031491A2 (en) 2000-10-11 2000-10-11 Apparatus and methods for affinity capture tandem mass spectrometry

Publications (1)

Publication Number Publication Date
CN1502116A true CN1502116A (zh) 2004-06-02

Family

ID=21741880

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA008199590A Pending CN1502116A (zh) 2000-10-11 2000-10-11 亲和捕获串联质谱分析设备和方法

Country Status (8)

Country Link
EP (1) EP1327256A2 (enExample)
JP (1) JP2004524511A (enExample)
KR (1) KR20040010541A (enExample)
CN (1) CN1502116A (enExample)
AU (1) AU2001210807A1 (enExample)
CA (1) CA2425456A1 (enExample)
IL (1) IL154932A0 (enExample)
WO (1) WO2002031491A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106055895A (zh) * 2010-09-15 2016-10-26 Dh科技发展私人贸易有限公司 产物离子光谱的数据独立获取及参考光谱库匹配
CN107092769A (zh) * 2012-05-18 2017-08-25 Dh科技发展私人贸易有限公司 用于在串联质谱分析中使用交错窗宽度的系统及方法
CN113049663A (zh) * 2021-01-27 2021-06-29 中国科学院成都生物研究所 一维线材样品转储及质谱分析的装置和使用方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10125258A1 (de) 2001-05-23 2003-01-09 November Ag Molekulare Medizin Verfahren zur Bestimmung des Bindeverhaltens von an Ziel-Molekülen spezifisch bindenden Liganden
GB2384778A (en) * 2001-12-21 2003-08-06 Sense Proteomic Ltd Probe for mass spectrometry
US7064319B2 (en) * 2003-03-31 2006-06-20 Hitachi High-Technologies Corporation Mass spectrometer
JP4605344B2 (ja) * 2003-06-10 2011-01-05 直久 友杉 シェーグレン症候群患者の検定方法
GB0404106D0 (en) * 2004-02-24 2004-03-31 Shimadzu Res Lab Europe Ltd An ion trap and a method for dissociating ions in an ion trap
JP4522910B2 (ja) * 2005-05-30 2010-08-11 株式会社日立ハイテクノロジーズ 質量分析方法及び質量分析装置
KR100805775B1 (ko) * 2005-08-08 2008-02-21 한국기초과학지원연구원 변형된 폴리펩티드(Ｍｏｄｉｆｉｅｄｐｏｌｙｐｅｐｔｉｄｅ)의 서열 및 변형 정보를 분석하는방법
KR101559101B1 (ko) * 2013-11-28 2015-10-12 한국기초과학지원연구원 혈액유래 암 진단용 펩티드 마커 및 이를 이용한 암 진단방법
CN115184530B (zh) * 2022-08-19 2023-11-24 北京中医药大学 一种多级在线能量分辨质谱法及其在结构精准鉴定中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498545A (en) * 1994-07-21 1996-03-12 Vestal; Marvin L. Mass spectrometer system and method for matrix-assisted laser desorption measurements

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106055895A (zh) * 2010-09-15 2016-10-26 Dh科技发展私人贸易有限公司 产物离子光谱的数据独立获取及参考光谱库匹配
CN107092769A (zh) * 2012-05-18 2017-08-25 Dh科技发展私人贸易有限公司 用于在串联质谱分析中使用交错窗宽度的系统及方法
CN107092769B (zh) * 2012-05-18 2020-07-10 Dh科技发展私人贸易有限公司 用于在串联质谱分析中使用交错窗宽度的系统及方法
CN113049663A (zh) * 2021-01-27 2021-06-29 中国科学院成都生物研究所 一维线材样品转储及质谱分析的装置和使用方法
CN113049663B (zh) * 2021-01-27 2023-10-20 中国科学院成都生物研究所 一维线材样品转储及质谱分析的装置和使用方法

Also Published As

Publication number Publication date
JP2004524511A (ja) 2004-08-12
WO2002031491A3 (en) 2003-01-09
AU2001210807A1 (en) 2002-04-22
CA2425456A1 (en) 2002-04-18
EP1327256A2 (en) 2003-07-16
WO2002031491A2 (en) 2002-04-18
KR20040010541A (ko) 2004-01-31
IL154932A0 (en) 2003-10-31

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