JP2004523211A - 高温ポリメラーゼ活性を有する酵素およびその使用方法 - Google Patents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US09/656,309 US7049101B1 (en) | 1997-08-06 | 2000-09-06 | Enzymes having high temperature polymerase activity and methods of use thereof |
| PCT/US2001/028007 WO2002020735A2 (en) | 2000-09-06 | 2001-09-06 | Enzymes having high temperature polymerase activity and methods of use thereof |
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| JP2004523211A true JP2004523211A (ja) | 2004-08-05 |
| JP2004523211A5 JP2004523211A5 (enExample) | 2005-04-28 |
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| CA (1) | CA2419975A1 (enExample) |
| WO (1) | WO2002020735A2 (enExample) |
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| AUPS115502A0 (en) * | 2002-03-18 | 2002-04-18 | Diatech Pty Ltd | Assessing data sets |
| KR20050052666A (ko) * | 2002-10-10 | 2005-06-03 | 다이버사 코포레이션 | 프로테아제, 이를 암호화하는 핵산, 및 이를 제조하고사용하는 방법 |
| US7960157B2 (en) * | 2002-12-20 | 2011-06-14 | Agilent Technologies, Inc. | DNA polymerase blends and uses thereof |
| AU2004277368B2 (en) | 2003-03-07 | 2011-01-20 | Dsm Ip Assets B.V. | Hydrolases, nucleic acids encoding them and mehods for making and using them |
| US20080070291A1 (en) | 2004-06-16 | 2008-03-20 | David Lam | Compositions and Methods for Enzymatic Decolorization of Chlorophyll |
| US8557551B2 (en) | 2004-09-10 | 2013-10-15 | Dsm Ip Assets B.V. | Compositions and methods for making and modifying oils |
| WO2006030455A1 (en) * | 2004-09-17 | 2006-03-23 | Prokaria Ehf. | Dna polymerases having strand displacement activity |
| WO2009135158A2 (en) * | 2008-05-02 | 2009-11-05 | Immunetics, Inc. | Detection of microbial nucleic acids |
| GB201007384D0 (en) | 2010-04-30 | 2010-06-16 | Medical Res Council | Enzymes |
| US9309501B2 (en) | 2012-12-24 | 2016-04-12 | Industrial Technology Research Institute | Isolated DNA polymerases, kits and applications thereof |
| US10494665B2 (en) * | 2014-08-20 | 2019-12-03 | Huawei Yang | Test kit and method for testing target nucleic acid in sample |
| WO2019143622A1 (en) | 2018-01-19 | 2019-07-25 | Bio-Rad Laboratories, Inc. | Mutant dna polymerases |
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| US1531A (en) * | 1840-03-31 | Kockiltor-chaib | ||
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| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| IL95738A (en) * | 1989-09-23 | 1996-11-14 | Hoechst Ag | Antibodies against the well-preserved amino acid sequences of insulin, a process for their preparation and use in immunoassay |
| US5322785A (en) | 1990-04-26 | 1994-06-21 | New England Biolabs, Inc. | Purified thermostable DNA polymerase obtainable from thermococcus litoralis |
| US5770429A (en) * | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5541311A (en) | 1992-12-07 | 1996-07-30 | Third Wave Technologies, Inc. | Nucleic acid encoding synthesis-deficient thermostable DNA polymerase |
| US5491086A (en) | 1993-05-14 | 1996-02-13 | Hoffmann-La Roche Inc. | Purified thermostable nucleic acid polymerase and DNA coding sequences from pyrodictium species |
| USH1531H (en) | 1994-04-18 | 1996-05-07 | Blumentals; Ilse I. | Thermophilic DNA polymerase |
| JP3132624B2 (ja) | 1994-05-09 | 2001-02-05 | 東洋紡績株式会社 | 超好熱始原菌由来のｄｎａポリメラーゼ遺伝子およびその用途 |
| JP3498808B2 (ja) | 1994-06-09 | 2004-02-23 | タカラバイオ株式会社 | Ｄｎａポリメラーゼ遺伝子 |
| US6077664A (en) | 1995-06-07 | 2000-06-20 | Promega Corporation | Thermophilic DNA polymerases from Thermotoga neapolitana |
| US5939250A (en) * | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
| EP0822256B1 (en) | 1996-07-29 | 2003-09-24 | Toyo Boseki Kabushiki Kaisha | Modified thermostable DNA polymerase, and DNA polymerase composition for nucleic acid amplification |
| US6057098A (en) * | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| US5948666A (en) * | 1997-08-06 | 1999-09-07 | Diversa Corporation | Isolation and identification of polymerases |
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