JP2004521952A - 脂肪分解を誘発するためのコルチコトロフ−誘導の糖タンパク質ホルモンの使用 - Google Patents

脂肪分解を誘発するためのコルチコトロフ−誘導の糖タンパク質ホルモンの使用 Download PDF

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Publication number
JP2004521952A
JP2004521952A JP2003511857A JP2003511857A JP2004521952A JP 2004521952 A JP2004521952 A JP 2004521952A JP 2003511857 A JP2003511857 A JP 2003511857A JP 2003511857 A JP2003511857 A JP 2003511857A JP 2004521952 A JP2004521952 A JP 2004521952A
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JP
Japan
Prior art keywords
cgh
lipolysis
individual
obesity
adipocytes
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JP2003511857A
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English (en)
Japanese (ja)
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JP2004521952A5 (enExample
Inventor
ディー. ケリー,ジェイムズ
ジェイ. ウェブスター,フィリッパ
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ザイモジェネティクス,インコーポレイティド
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Publication of JP2004521952A publication Critical patent/JP2004521952A/ja
Publication of JP2004521952A5 publication Critical patent/JP2004521952A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003511857A 2001-07-13 2002-07-15 脂肪分解を誘発するためのコルチコトロフ−誘導の糖タンパク質ホルモンの使用 Pending JP2004521952A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30528401P 2001-07-13 2001-07-13
PCT/US2002/022747 WO2003006051A1 (en) 2001-07-13 2002-07-15 Use of corticotroph-derived glycoprotein hormone to induce lipolysis

Publications (2)

Publication Number Publication Date
JP2004521952A true JP2004521952A (ja) 2004-07-22
JP2004521952A5 JP2004521952A5 (enExample) 2006-01-05

Family

ID=23180168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003511857A Pending JP2004521952A (ja) 2001-07-13 2002-07-15 脂肪分解を誘発するためのコルチコトロフ−誘導の糖タンパク質ホルモンの使用

Country Status (7)

Country Link
US (2) US20030095983A1 (enExample)
EP (1) EP1414485A1 (enExample)
JP (1) JP2004521952A (enExample)
CA (1) CA2454181A1 (enExample)
IL (1) IL159526A0 (enExample)
WO (1) WO2003006051A1 (enExample)
ZA (1) ZA200400060B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1395580A (zh) * 2000-01-18 2003-02-05 阿克佐诺贝尔公司 人类胱氨酸结多肽
IL165474A0 (en) * 2002-06-10 2006-01-15 Zymogenetics Inc Use of corticortoph-derived glycoprotein hormone to treat inflammation and potentiate glucocoritcoidaction
CA2547631A1 (en) * 2003-12-05 2005-06-23 Zymogenetics, Inc. Methods for treating inflammation using thyroid stimulating hormone
US20050272635A1 (en) * 2004-03-05 2005-12-08 Kelly James D Use of corticotroph-derivced glycoprotein hormone to treat liver steatosis
JP5118292B2 (ja) * 2005-06-16 2013-01-16 株式会社ロッテ 脂肪分解促進剤
WO2007005320A2 (en) * 2005-06-29 2007-01-11 Zymogenetics, Inc. Methods of delivering corticotroph-derived glycoprotein hormone
AU2006331619B2 (en) * 2005-12-23 2012-12-20 James D. Kelly Improved thyroid-stimulating hormone receptor polypeptide agonist glycoforms to treat metabolic syndrome

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69932804T2 (de) * 1998-02-13 2007-08-23 Zymogenetics, Inc., Seattle Protein, welches durch einen cystinknoten charakterisiert ist und verfahren zu dessen herstellung
WO2000078964A1 (en) * 1999-06-17 2000-12-28 Amgen Inc. Glycoprotein hormone family member
US20020068279A1 (en) * 1999-12-06 2002-06-06 Curagen Corporation Novel Proteins and nucleic acids encoding the same
US7514239B2 (en) * 2000-03-28 2009-04-07 Amgen Inc. Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
US20040005554A1 (en) * 2000-05-08 2004-01-08 Tayar Nabil El Novel glycoproteins and methods of use thereof

Also Published As

Publication number Publication date
US20030095983A1 (en) 2003-05-22
WO2003006051A1 (en) 2003-01-23
IL159526A0 (en) 2004-06-01
ZA200400060B (en) 2004-08-17
CA2454181A1 (en) 2003-01-23
EP1414485A1 (en) 2004-05-06
US20060035818A1 (en) 2006-02-16

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