JP2004500411A - 癌の発達の阻害のための、ブチルニトロンを含む組成物 - Google Patents

癌の発達の阻害のための、ブチルニトロンを含む組成物 Download PDF

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JP2004500411A
JP2004500411A JP2001572094A JP2001572094A JP2004500411A JP 2004500411 A JP2004500411 A JP 2004500411A JP 2001572094 A JP2001572094 A JP 2001572094A JP 2001572094 A JP2001572094 A JP 2001572094A JP 2004500411 A JP2004500411 A JP 2004500411A
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Japan
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pbn
tert
development
nitrone
diet
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JP2001572094A
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English (en)
Japanese (ja)
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JP2004500411A5 (enExample
Inventor
フロイド, ロバート エイ.
古武 弥成
ヘンズリー, ケネス
中江 大
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Oklahoma Medical Research Foundation
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Oklahoma Medical Research Foundation
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Publication of JP2004500411A publication Critical patent/JP2004500411A/ja
Publication of JP2004500411A5 publication Critical patent/JP2004500411A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2001572094A 2000-03-30 2001-03-28 癌の発達の阻害のための、ブチルニトロンを含む組成物 Pending JP2004500411A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19357200P 2000-03-30 2000-03-30
PCT/US2001/010508 WO2001074349A1 (en) 2000-03-30 2001-03-28 Butylnitrone containing compositons for inhibition of cancer development

Publications (2)

Publication Number Publication Date
JP2004500411A true JP2004500411A (ja) 2004-01-08
JP2004500411A5 JP2004500411A5 (enExample) 2008-05-15

Family

ID=22714183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001572094A Pending JP2004500411A (ja) 2000-03-30 2001-03-28 癌の発達の阻害のための、ブチルニトロンを含む組成物

Country Status (6)

Country Link
US (1) US6569902B2 (enExample)
EP (1) EP1267860A1 (enExample)
JP (1) JP2004500411A (enExample)
AU (1) AU785365B2 (enExample)
CA (1) CA2404291A1 (enExample)
WO (1) WO2001074349A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
US20060235370A1 (en) * 2005-04-04 2006-10-19 Oblong John E Method of regulating mammalian keratinous tissue
EP1922075A4 (en) * 2005-08-04 2009-10-14 Oklahoma Med Res Found ADJUVANT CHEMOTHERAPY FOR ANAPLASTIC GLIOMAS
JP5236641B2 (ja) * 2006-07-25 2013-07-17 ハフ イヤ インスティテュート 急性音響外傷の治療方法
CA2735859C (en) 2008-09-02 2016-08-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl tert-butyl nitrone for the treatment of gliomas
CN110373380B (zh) * 2019-06-14 2022-01-28 中国科学院生态环境研究中心 一种肝脏类器官模型及其建立方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0925263A (ja) * 1989-10-17 1997-01-28 Oklahoma Medical Res Found 酸化的損傷に伴う疾患を阻止する化合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0925263A (ja) * 1989-10-17 1997-01-28 Oklahoma Medical Res Found 酸化的損傷に伴う疾患を阻止する化合物

Also Published As

Publication number Publication date
US20020004531A1 (en) 2002-01-10
US6569902B2 (en) 2003-05-27
CA2404291A1 (en) 2001-10-11
WO2001074349A1 (en) 2001-10-11
AU785365B2 (en) 2007-02-08
EP1267860A1 (en) 2003-01-02
AU4791501A (en) 2001-10-15

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