JP2004329136A - Treating vessel and treating apparatus - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a treating vessel capable of rapidly and easily feeding a treating liquid to two or more supporters to which a material to be treated is attached; and to provide a treating apparatus. <P>SOLUTION: The treating apparatus has the treating vessel 2 having two or more treating parts 4 for allowing the treating liquid to be inserted into the interior, and arranged through partitions 2, and treating the material to be treated by installing the supporters to which the material to be treated is attached in each of the treating parts 4, and a tilting structure for tilting or leveling the treating vessel 2. The treating vessel 2 has functions for allowing the treating liquid fed to the interior to communicate with each other in a state of the treating part 4 tilted in a prescribed direction, and for distributing the fed treating liquid to each treating part 4 when the treating vessel is returned to the horizontal state from the tilted state. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a processing tank and a processing apparatus.
[0002]
[Prior art]
For example, when performing a process such as hybridization for nucleic acids (RNA, DNA), a nucleic acid (object to be treated) is attached to a plate (support), and a treatment solution is supplied to the nucleic acid (contact). Processing) is performed.
[0003]
As a method of bringing the nucleic acid into contact with the treatment liquid, the treatment liquid is dropped on each support, and further, a developing member is overlapped thereon, and the treatment liquid is filled in a gap formed therebetween. By developing, the nucleic acid is brought into contact with the treatment liquid.
[0004]
In the conventional processing tank and processing apparatus, a cover plate (development member) 560 is superimposed on a microarray M which is a plate (support) P to which an object to be processed is attached, and a gap formed between the microarray M and the microarray M. In 569, a processing liquid for processing the object to be processed is developed (for example, see Patent Document 1). Note that the code used here is the code described in Patent Document 1.
[0005]
However, in the above-described sample processing tank and processing apparatus, when processing a plurality of microarrays (plates), it is time-consuming because the processing liquid must be individually dropped on each microarray using a dispenser or the like. was there.
[0006]
[Patent Document 1]
JP-A-2003-57245 (FIG. 3)
[0007]
[Problems to be solved by the invention]
An object of the present invention is to provide a processing tank and a processing apparatus capable of quickly and easily supplying a processing liquid to a plurality of supports to which an object to be processed is attached.
[0008]
[Means for Solving the Problems]
Such an object is achieved by the following (1) to (14) of the present invention.
[0009]
(1) A processing tank in which a plurality of processing units for putting a processing liquid therein are arranged side by side through a partition, and a support having an object to be processed attached thereto is installed in each processing unit to perform processing.
In a state where the processing section is tilted in a predetermined direction, the processing liquid supplied therein conducts to one, and when the processing section is brought into a horizontal state from that state, the supplied processing liquid is supplied to each of the processing sections. A treatment tank, wherein the treatment tank is distributed to parts.
[0010]
(2) A processing tank in which a plurality of long processing sections into which a processing solution is to be put are arranged side by side through a partition, and a support on which an object to be processed is attached is installed in each of the processing sections. hand,
In a state where the processing tank is tilted so that one end of the processing unit is raised, the processing liquid supplied to the inside of the processing unit passes through each of the partition walls and conducts to one, and then the processing unit is in a horizontal state. Wherein the supplied processing liquid is distributed to each of the processing units.
[0011]
(3) an inner tank provided with the partition,
Having an outer tank capable of storing the inner tank,
Openings are respectively provided on the bottom surface of a portion corresponding to each processing unit of the inner tank,
The support is provided between the bottom surface of the inner tank and the bottom surface of the outer tank, and the portions of the support to which the object to be processed adhere are exposed from the openings, respectively. ).
[0012]
(4) The processing tank according to any one of (1) to (3), wherein at least one hole for supplying and / or discharging the processing liquid is provided.
[0013]
(5) Any of the above (1) to (4), wherein a tapered surface is formed between a bottom surface of each of the processing units and a lowermost side surface when the processing tank is in the inclined state. The processing tank described in 1.
[0014]
(6) The processing tank according to (5), wherein the partition wall is formed from a side surface located opposite to the tapered surface side to a middle of the tapered surface.
[0015]
(7) The processing tank according to any one of (1) to (6), further including a positioning unit on a bottom surface of the processing unit for preventing the support from moving with respect to the processing tank.
[0016]
(8) The treatment tank according to any one of (1) to (7),
A processing apparatus, comprising: a tilt mechanism that displaces the processing tank between the tilted state and the horizontal state.
[0017]
(9) The processing apparatus according to (8), wherein, when discharging the processing liquid, the processing tank is tilted and discharged by the tilt mechanism.
[0018]
(10) The tilt mechanism includes a base,
A hinge connection portion serving as a rotation center of the processing tank with respect to the base;
The processing apparatus according to the above (8) or (9), further comprising: a rotation unit configured to rotate the processing tank by using the hinge joint.
[0019]
(11) In order to clean the portion to which the object is attached and / or the processing unit, the supplied cleaning liquid is stirred in the processing unit by the operation of the tilting mechanism to attach the object. The processing apparatus according to any one of the above (8) to (10), which cleans a part and / or the processing unit.
[0020]
(12) The processing apparatus according to any one of (8) to (11), wherein the processing liquid is a reaction liquid capable of reacting with the object to be processed.
[0021]
(13) The processing apparatus according to any one of (8) to (12), wherein the object is a nucleic acid.
[0022]
(14) The processing apparatus according to (13), wherein the processing liquid is a liquid containing a probe capable of reacting with the nucleic acid.
[0023]
BEST MODE FOR CARRYING OUT THE INVENTION
Hereinafter, a processing tank and a processing apparatus of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
[0024]
In the following, a nucleic acid (DNA, cDNA, RNA, etc.) is represented as an example of the object to be treated, and a microarray (DNA chip) in which the nucleic acid (nucleic acid fragment) is attached to a plate (support) in a scattered manner. A case in which the processing apparatus of the present invention is applied to a microarray processing apparatus for processing the above will be described.
[0025]
Further, as an example of the treatment liquid (reaction liquid), a nucleic acid (for example, mRNA, DNA, etc.) collected from a subject, or a nucleic acid (for example, cDNA, etc.) synthesized based on this nucleic acid is labeled (for example, a dye, A liquid containing a substance (labeled with a substance, a radioactive substance, or the like) (hereinafter, referred to as a “probe liquid”) will be described as a representative.
[0026]
The treatment referred to herein preferably refers to hybridization of the nucleic acid adhered to the plate in a scattered manner with the nucleic acid or probe contained in the probe solution.
[0027]
<First embodiment>
1 and 2 are overall configuration diagrams showing an embodiment of the processing apparatus of the present invention. In the following, for convenience of explanation, the upper side in FIG. 1 (also in FIG. 2) is referred to as “upper” or “upper”, and the lower side is referred to as “lower” or “lower”.
[0028]
The processing apparatus 1 shown in FIGS. 1 and 2 has a processing tank 2 and an inclination mechanism 3 for displacing the processing tank 2 between an inclined state and a substantially horizontal state.
[0029]
In the processing apparatus 1 of the present invention, it is preferable that the processing tank 2 is housed in a hermetically sealed airtight tank (not shown) and the processing is performed in an environment in which temperature and humidity are controlled.
[0030]
Hereinafter, the configuration of each unit will be described.
The tilt mechanism 3 has a base 33, a hinge (hinge joint) 31, and an air cylinder (rotating means) 32. The hinge 31 is a mechanism for rotatably connecting the base 33 and the bottom plate (bottom surface) 21 of the processing tank 2. The air cylinder 32 is rotatably coupled to the base 33 and the bottom plate 21 at both longitudinal ends thereof. The tilting mechanism 3 tilts or horizontalizes the processing tank 2 with respect to the base 33 around the hinge 31 by extending and contracting the air cylinder 32. The processing apparatus 1 tilts the processing tank 2 when supplying the probe liquid (processing liquid) R into the processing tank 2 by the tilting mechanism 3 and causes the probe liquid R to react with the nucleic acid (object to be processed) S. The processing tank 2 is made horizontal.
[0031]
According to the processing apparatus 1, the nucleic acid S can be reacted with the probe liquid R and the nucleic acid S can be treated with various liquids. From the reaction results of the nucleic acid S, for example, mutation analysis of gene DNA (nucleic acid), polymorphism analysis, base sequence analysis, expression analysis (presence / absence), and diagnosis of various diseases based on these are performed. It can be suitably performed.
[0032]
The rotating means for rotating the processing tank 2 about the hinge 31 as a center of rotation is not limited to the air cylinder 32 but may be, for example, a motor drive, a gear mechanism, or the like. Further, the tilting mechanism 3 is not limited to the mechanism using the hinge 31, and may have any structure as long as the mechanism can displace the processing tank 2 to an inclined posture.
[0033]
FIG. 3 is a perspective view showing a first embodiment of the processing tank of the present invention. FIG. 4 is a cross-sectional view taken along line AA of FIG. 3 when the processing tank 2 is tilted by the tilting mechanism 3 and the probe liquid R is supplied into the processing tank 2 from the supply / discharge port 221. FIG. 5 is a cross-sectional view taken along the line AA of FIG. 3 when the processing tank 2 in the state of FIG. In the following, for convenience of description, the upper side in FIG. 3 (the same applies to FIGS. 4, 5 and 6) is referred to as “upper” or “upper”, and the lower side is referred to as “lower” or “lower”. However, the size of the nucleic acid S in FIG. 3 (also in FIGS. 4, 5, 6, 7, and 8) is exaggerated for the sake of explanation.
[0034]
The processing bath 2 shown in FIG. 3 includes a bottom plate 21, side walls 22, a tapered surface (inclined surface) 23, and a partition 24 that partitions the inside of the processing bath 2 into a plurality of spaces. Although the processing tank 2 of the present embodiment has a configuration in which these components are integrally formed, the processing tank 2 may be configured by combining a plurality of members.
The side wall 22 is formed around the entire periphery of the bottom plate 21.
[0035]
In this embodiment, two partition walls 24 are provided, and are arranged in parallel with each other at intervals. The inner space of the processing tank 2 is partitioned into three spaces by these partition walls 24, and each of these spaces constitutes a processing unit 4 into which the probe liquid R is charged.
[0036]
In the present invention, the number of the processing units 4 is not particularly limited, and four or more processing units 4 may be provided by providing three or more partition walls 24.
[0037]
These processing units 4 are arranged in a direction orthogonal to the partition wall 24. In addition, the shape of the region of each processing unit 4 has a long shape (elongated shape) that is long in a direction orthogonal to the arranged direction. When the processing tank 2 is tilted by the tilting mechanism 3, one end (the right side in FIG. 3) of the processing unit 4 rises to a position higher than the other end (the left side in FIG. 3).
[0038]
The bottom plate 21 forms the bottom of the processing unit 4. As shown in FIG. 4, a recess (positioning means) 211 having a shape corresponding to the plate P is formed on a surface above the bottom plate 21 in each processing unit 4. By disposing the plate P in the concave portion 211, the plate P can be positioned on the bottom plate 21, and the position of the plate P can be more reliably prevented from shifting even when the processing tank 2 is inclined.
[0039]
The side wall 22 is provided with one liquid supply / drain port (hole) 221. The probe liquid R can be supplied or discharged from the supply / drain port 221. Conventionally, a supply / drainage port must be provided for each processing unit. However, in the present invention, as will be described later, since the probe liquid R can flow between the processing units 4, the processing tank 2 can supply the probe liquid R sufficiently if only one supply / drain port 221 is provided. And can be discharged.
[0040]
A tapered surface (inclined surface) 23 is formed between the bottom plate 21 and the side wall 22a located at the lowest position when the processing tank 2 is inclined by the inclination mechanism 3. The tapered surface 23 is inclined with respect to the bottom plate 21 so that the height increases from the bottom plate 21 toward the side wall 22a.
[0041]
The partition wall 24 is formed from the side wall 22 b opposite to the side of the tapered surface 23 to a part of the tapered surface 23. In other words, a gap 25 where the partition wall 24 is not formed is provided near the side wall 22a. The gap 25 functions as a passage (liquid passage section) for allowing the probe liquid R to flow between the processing sections 4.
[0042]
As shown in FIG. 4, when the processing apparatus 1 supplies the probe liquid R into the processing tank 2, the processing liquid is supplied through the supply / drain port 221 by a processing liquid supply unit (not shown) while the processing tank 2 is inclined. To send the probe solution R into the processing tank 2.
[0043]
In addition, as the processing liquid supply mechanism, for example, a mechanism that sucks up the probe liquid R stored in the storage unit by a pump and supplies the probe liquid R to the supply / drainage port 221 from the pump using a pipe can be cited.
[0044]
In the state shown in FIG. 4, the probe liquid R supplied to the inside of the processing tank 4 is conducted to one through the partition wall 24 and spreads to each processing unit 4. In other words, the probe liquid R passes through the gap (passage) 25 at the end (the left side in FIG. 4) of each processing unit 4 on the tapered surface 23 side, and the probe liquid R can move relative to each other. For this reason, they are connected to one another in a direction orthogonal to the paper surface of FIG.
[0045]
At this time, in the present embodiment, the provision of the tapered surface 23 allows the probe liquid R to be distributed to each processing unit 4 in a smaller amount.
[0046]
The processing apparatus 1 may tilt the processing tank 2 after supplying the probe liquid R into the processing tank 2 in a state where the processing tank 2 is horizontal.
[0047]
When the processing tank 2 is returned to the horizontal posture from the state shown in FIG. 4, the probe liquid R is distributed to each processing unit 4 while flowing toward the side wall 22b, and covers the microarray M, as shown in FIG. The depths of the probe liquids R covering the microarray M are the same. Further, since the processing units 4 are partitioned by the partition walls 24, the probe liquid R does not move between the processing units 4 beyond the partition walls 24 in the state shown in FIG. However, the liquid level of the probe liquid R at this time is preferably lower than the lowermost part 251 of the gap 25. Then, the amount of the probe liquid R in each processing section 4 thereafter does not change.
[0048]
Conventionally, since a dispensing device or the like was used, it was necessary to quantify the amount of the probe solution R to be dispensed, and drop (dispense) the probe solution R on each microarray M individually. However, in the processing apparatus 1, the following operation can be easily and quickly performed only by leveling the processing tank 2. First, the probe liquid R held (supplied) near the gap 25 while the processing tank 2 is tilted by the tilting mechanism 3 is transferred to each processing unit 4 when the processing tank 2 is displaced to a horizontal state. Distributed. Further, the water depth of the probe liquid R distributed to each processing unit 4 is the same. Next, since the respective probe liquids R do not move (cannot move) between the processing units 4 due to the partition walls 24, the amounts of the probe liquids R are kept constant and unchanged.
[0049]
Further, in the processing apparatus 1, when the processing tank 2 is leveled by the tilting mechanism 3 in a state where the probe liquid R is contained in the inclined processing tank 2, the depth of the probe liquid R becomes the same. Therefore, the amount of the probe liquid R corresponding to the width of each processing unit 4 enters each processing unit 4. For example, if the widths of the processing units 2 are equal, the same amount of the probe liquid R enters each processing tank 2.
[0050]
FIG. 6 is a cross-sectional view taken along the line AA of FIG. 3 when the inclination of the treatment tank 2 in the state of FIG. At this time, the probe liquid R collected in the vicinity of the gap 25 covers all or a part of the liquid supply / drain port 221 and is naturally discharged from the liquid supply / drain port 221. As described above, when the probe liquid R is discharged, the probe liquid R is discharged through the tilting mechanism 3 and the supply / drain port 221. In other words, since there is no need to provide a mechanism for discharging the probe liquid R in the processing tank 2 to the outside of the processing tank 2 using, for example, a pump and a pipe, the apparatus can be downsized and the structure can be simplified.
[0051]
The configuration for keeping the processing tank 2 in a closed environment as described above is not particularly limited. For example, a lid may be provided on the processing tank 2 and the processing tank 2 itself may have a processing tank sealing function. In addition, not only the treatment tank 2 but also the tilting mechanism 3 may be housed in a closed tank.
[0052]
When cleaning the portion where the nucleic acid S has reacted with the probe liquid R and the processing section 4, the cleaning liquid is supplied to the processing tank 2 by a cleaning liquid supply unit (not shown). Next, the processing tank 2 is repeatedly displaced as shown in FIGS. 1 and 2 by the operation of the tilting mechanism 3. Thus, the washing liquid is stirred in the processing section 4 to wash the portion where the nucleic acid S has reacted with the probe liquid R and the processing tank 4. Further, the cleaning liquid after the cleaning is discharged in the same manner as in FIG. As described above, even in the cleaning of the processing unit 4, the processing apparatus 1 can perform the operation by using the operation of the tilt mechanism 3, and the tilt mechanism 3 is used for multiple purposes, so that the structure can be rationalized. Also, in the discharge of the cleaning liquid, the processing apparatus 1 can discharge the cleaning liquid through the supply / drainage port 221. In other words, since it is not necessary to provide a flushing mechanism having a flushing function, the size of the apparatus can be reduced and the structure can be simplified.
[0053]
In this embodiment, for example, as shown in FIG. 3, the tapered surface is formed not only inside the processing tank 2 (the processing unit 4) but also outside the processing tank 2. It may be formed only inside the portion 4).
[0054]
<Second embodiment>
FIG. 7 is an exploded perspective view showing a second embodiment of the processing tank of the present invention. In the following, for convenience of description, the upper side in FIG. 7 (also in FIG. 8) is referred to as “up” or “upper”, and the lower side is referred to as “lower” or “lower”.
[0055]
Hereinafter, the second embodiment of the present invention will be described with reference to these drawings, but the description will focus on the differences from the above-described first embodiment, and a description of similar items will be omitted.
[0056]
This embodiment is the same as the first embodiment except that the configuration of the processing tank is different.
[0057]
The processing tank 2A of the first embodiment is different from the processing tank 2 of the first embodiment in that the processing tank 2A of the first embodiment is configured by combining two tanks, an inner tank 5 and an outer tank 6 capable of storing the inner tank 5. different.
[0058]
The inner tank 5 has substantially the same shape as the processing tank 2 of the first embodiment, and has a bottom plate (bottom surface) 51, a side wall 52, a tapered surface 53, and a partition for partitioning the inside of the inner tank 2 into a plurality of spaces. 54. Although the inner tank 2 of the present embodiment has a configuration in which these components are integrally formed, the inner tank 2 may be configured by combining a plurality of members.
[0059]
The bottom plate 51 constitutes the bottom of the inner tank 5 and has an opening 511. The openings 511 are provided respectively corresponding to the processing units 4 described below.
The side wall 52 is formed on the entire outer periphery of the bottom plate 51.
[0060]
A tapered surface (inclined surface) 53 is formed between the bottom plate 51 and the side wall 52a located at the lowest position when the processing tank 2A is inclined by the inclination mechanism 3. The tapered surface 53 is inclined with respect to the bottom plate 51 so that the height increases from the bottom plate 51 toward the side wall 52a.
[0061]
In the present embodiment, two partition walls 54 are provided, and are arranged in parallel with each other at intervals. The inner space of the inner tank 5 is partitioned into three spaces by these partition walls 54, and each of these spaces constitutes the processing unit 4 in which the probe liquid R is charged. Further, the partition wall 54 is formed from the side wall 52 b located on the opposite side to the side of the tapered surface 53 to the middle of the tapered surface 53. In other words, a gap 55 where the partition wall 54 is not formed is provided near the side wall 52a.
[0062]
The outer tub 6 has a bottom plate (bottom surface) 61 and side walls 62. The outer tub 6 of the present embodiment has a configuration in which these components are integrally formed. However, the outer tub 6 may be configured by combining a plurality of members.
[0063]
The bottom plate 61 forms the bottom of the outer tub 6.
The side wall 62 is formed all around the outer peripheral portion of the bottom plate 61.
[0064]
FIG. 8 is a cross-sectional view taken along the line BB showing the use state of the processing tank 2A in FIG. At this time, the plate P is installed between the bottom plate 51 of the inner tank 5 and the bottom plate 61 of the outer tank 6. Further, the portions to which the nucleic acids S are attached are exposed from the openings 511 and covered with the probe solution R. In the present embodiment, in order to process the microarray M, it is sufficient to cover only the portions where the nucleic acids S exposed from the openings 511 are attached with the probe solution R, and it is not necessary to cover the entire plate P with the probe solution R. Therefore, in this embodiment, only the opening 511 needs to be covered with the probe liquid R, and the use of the probe liquid R can be minimized.
[0065]
In the present embodiment, since the plate P is sandwiched between the bottom plate 51 and the bottom plate 61, it is possible to more reliably prevent the position of the plate P from shifting even when the processing tank 2A is tilted. it can. That is, the bottom plate 51 and the bottom plate 61 function as positioning means for the plate P.
[0066]
As described above, the processing tank and the processing apparatus of the present invention have been described with respect to the illustrated embodiment. However, the present invention is not limited to this, and each unit constituting the processing tank and the processing apparatus exhibits the same function. It can be replaced with any configuration obtained. Further, an arbitrary component may be added.
[0067]
【The invention's effect】
As described above, according to the present invention, when applying a processing liquid to a plurality of supports to which an object to be processed is attached, it is not necessary to apply the processing liquid to each support individually, and the processing liquid can be quickly and easily applied. Each support can be contacted.
[0068]
In addition, the configuration of the processing tank has an inner tank provided with a partition wall, and an outer tank capable of storing the inner tank, and an opening is provided on the bottom surface of a portion corresponding to each processing unit of the inner tank. In the case where the plurality of supports are provided between the bottom surface of the inner tank and the bottom surface of the outer tank, and the portions of the plurality of supports to which the objects to be processed adhere are respectively exposed from the openings. Thus, the amount of the processing solution used can be minimized.
[0069]
Further, when the processing tank has a tapered surface formed between the bottom surface of the processing unit and the lowermost side surface when the processing tank is tilted, the processing liquid is tilted when the processing tank is tilted. Can be distributed to the processing units in a smaller amount.
[0070]
For this reason, according to the present invention, for example, a search for a cancer gene, a mutant gene, and the like can be performed more easily and efficiently.
[Brief description of the drawings]
FIG. 1 is an overall configuration diagram showing an embodiment of a processing apparatus of the present invention.
FIG. 2 is an overall configuration diagram showing an embodiment of a processing apparatus of the present invention.
FIG. 3 is a perspective view showing a first embodiment of the processing tank of the present invention.
4 is a cross-sectional view taken along line AA of FIG. 3 when the processing tank 2 is tilted by the tilting mechanism 3 and the probe liquid R is supplied into the processing tank 2 from the supply / drain port 221.
FIG. 5 is a cross-sectional view taken along line AA of FIG. 3 when the processing tank 2 in the state of FIG.
6 is a sectional view taken along line AA of FIG. 3 when the inclination of the processing tank 2 in the state of FIG. 5 is made larger than that of FIG.
FIG. 7 is an exploded perspective view showing a second embodiment of the processing tank of the present invention.
FIG. 8 is a sectional view taken along the line BB showing a use state of the processing tank of FIG. 7;
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 Processing apparatus 2 Processing tank 2A Processing tank 21 Bottom plate 211 Depression 22 Side wall 22a Side wall 22b Side wall 221 Supply / drainage port 23 Tapered surface 24 Partition wall 25 Gap 251 Lowermost part 3 Inclination mechanism 31 Hinge 32 Air cylinder 33 Base 4 Processing part 5 Bath 51 Bottom plate 511 Opening 52 Side wall 52 a Side wall 52 b Side wall 53 Tapered surface 54 Partition wall 55 Gap 6 Outer bath 61 Bottom plate 62 Side wall M Microplate P Plate R Probe solution S Nucleic acid

Claims (14)

A plurality of processing units into which a processing liquid is to be placed are arranged side by side via a partition, and a processing tank for processing by installing a support having an object to be processed attached to each processing unit,
In a state where the processing section is tilted in a predetermined direction, the processing liquid supplied therein conducts to one, and when the processing section is brought into a horizontal state from that state, the supplied processing liquid is supplied to each of the processing sections. A treatment tank, wherein the treatment tank is distributed to parts. A plurality of long processing units into which a processing liquid is to be placed are arranged side by side via a partition, and a processing tank that performs processing by installing a support having an object to be processed attached to each processing unit,
In a state where the processing tank is tilted so that one end of the processing unit is raised, the processing liquid supplied to the inside of the processing unit passes through each of the partition walls and conducts to one, and then the processing unit is in a horizontal state. Wherein the supplied processing liquid is distributed to each of the processing units. An inner tank provided with the partition wall,
Having an outer tank capable of storing the inner tank,
Openings are respectively provided on the bottom surface of a portion corresponding to each processing unit of the inner tank,
The said support is installed between the bottom surface of the said inner tank, and the bottom surface of the said outer tank, The part to which the said to-be-processed object of the said support adhered is each exposed from the said opening part. Processing tank. 4. The processing tank according to claim 1, wherein at least one hole for supplying and / or discharging the processing liquid is provided. The processing tank according to claim 1, wherein a tapered surface is formed between a bottom surface of each of the processing units and a lowermost side surface when the processing tank is in the inclined state. The processing tank according to claim 5, wherein the partition wall is formed from a side surface opposite to the tapered surface side to a middle of the tapered surface. The processing tank according to any one of claims 1 to 6, further comprising a positioning means on a bottom surface of the processing unit for preventing the support from moving with respect to the processing tank. A treatment tank according to any one of claims 1 to 7,
A processing apparatus, comprising: a tilt mechanism that displaces the processing tank between the tilted state and the horizontal state. The processing apparatus according to claim 8, wherein when discharging the processing liquid, the processing tank is tilted and discharged by the tilt mechanism. The tilt mechanism includes a base,
A hinge connection portion serving as a rotation center of the processing tank with respect to the base;
The processing apparatus according to claim 8, further comprising a rotation unit configured to rotate the processing tank by using the hinge connection part. In order to clean the portion to which the object is attached and / or the processing unit, the supplied cleaning liquid is stirred in the processing unit by the operation of the tilting mechanism, and / or the part to which the object is attached. 11. The processing apparatus according to claim 8, wherein the processing unit is cleaned. The processing apparatus according to claim 8, wherein the processing liquid is a reaction liquid capable of reacting with the object. The processing apparatus according to claim 8, wherein the object is a nucleic acid. The processing apparatus according to claim 13, wherein the processing liquid is a liquid containing a probe capable of reacting with the nucleic acid.

Images