JP2004261119A - Functional health food or beverage - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To develop a health food or beverage having excellent functionalities such as an antiobestic property. <P>SOLUTION: The functional health food or beverage comprises lees of rice wine and rice bran, and as necessary, further, a sweetener such as sugar, honey bee, starch syrup, an acidulant such as lactic acid, tartaric acid or gluconic acid, a flavoring agent, a coloring agent and various components such as common salt, starch, ginger and water. The health food or beverage is not directly used only for drinking or eating, but can be used also as a foodstuff for food products and beverage products and is effective for suppression of obesity, improvement of blood lipid, vasodepressor and suppression of amnesia and has no problem on safety. As a result, the food or beverage can not only be taken in human bodies for a long period for medical application, but also for health application. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a functional health food or drink, and more particularly, a functional health food or drink according to the present invention contains sake lees and rice koji, and has an anti-obesity effect and an improvement in blood lipids. It has many excellent functions such as action, learning and memory improving action (amnesia inhibitory action), and blood pressure lowering action. Especially suitable for long-term ingestion.
[0002]
[Prior art]
In recent years, the number of lifestyle-related diseases such as increased blood lipids and blood pressure, including obesity due to the westernization of dietary habits, and the number of dementia and amnesia patients associated with an aging society have been increasing. Potential potential patients are increasing further and are expanding to younger generations, which is a major social problem.
[0003]
Various drugs have been developed to prevent, ameliorate, and treat these conditions, and some of them have been put to practical use. The present invention, in place of the drug, in particular, from the viewpoint of safety and continuity, food and drink, especially using a specific material of sake lees and rice koji, and are used by mixing both, sake lees, The residue obtained by squeezing sake moromi to separate sake and used as a raw material for edible, pickled, and shochu shochu (see Non-Patent Document 1, for example). It is used not only as a raw material for producing sake and miso, but also for producing sweet sake by adding it to white rice and saccharifying it into a porridge (for example, Non-Patent Document 2).
[0004]
As described above, sake lees and rice koji are used for various food applications, but by using both in combination, it is possible that the effects of anti-obesity, blood lipid improvement, learning and memory improvement, and blood pressure lowering are exhibited. , Not yet reported.
[0005]
[Non-patent document 1]
"Encyclopedia of Food Industry", Korin, October 25, 1979, p. 379
[0006]
[Non-patent document 2]
Encyclopedia of Food Industry, Korin, October 25, 1979, p. 31
[0007]
[Problems to be solved by the invention]
Obesity is mainly caused by lifestyle, and its onset takes a relatively long time. Therefore, to prevent or control its onset, it is not only highly effective but also for long-term use. Recognizing that it is necessary to have high safety and excellent palatability (easy to take), the present inventors focused on food and drink and food and drink raw materials, We decided to use. That is, the present invention has been made for the purpose of developing a health food or drink having excellent functionality such as anti-obesity property.
[0008]
[Means for Solving the Problems]
The present inventors have succeeded in establishing each experimental system of an obesity test, a blood pressure test, and a learning and memory test in a mouse first, in order to achieve the above object, and conducted a mouse in vivo test on various foodstuffs. Was used to evaluate the functionality. As a result, when sake lees was added to amazake made from rice koji and white rice, it was found for the first time that it had anti-obesity, blood lipid improvement, learning memory improvement, blood pressure lowering effects, and focusing on this new finding, Similarly, rice koji was added to amazake using sake lees (hereinafter also referred to as sake lees amazake), and the functional evaluation was carried out. Was completed.
[0009]
That is, the present invention newly provides a beverage or food having functions such as anti-obesity, improvement of blood lipids, improvement of learning and memory, and blood pressure lowering action by using sake lees and rice koji.
[0010]
The functional food or drink according to the present invention contains sake lees and rice koji as essential components, and may be composed of only sake lees and rice koji, or may be made into a beverage by adding water. Further, sweeteners such as sugar, honey, water syrup, oligosaccharides, stevia and the like may be added as a seasoning component, and if desired, sour seasonings, salt, ginger, plum extract and other seasonings having a taste. Ingredients, starch, flavors and the like may be added.
[0011]
In addition, amazake can also be used. For example, besides amazake produced not only sake lees but also rice koji as a raw material (hereinafter also referred to as sake lees amazake with rice koji), sake lees amazake may be additionally prepared with rice koji. Additions can be used, and in the case of amazake obtained by saccharifying white rice using rice koji and white rice as raw materials, those obtained by adding sake lees thereto can be used as appropriate.
[0012]
As the sake lees amazake with rice koji, for example, the following composition is exemplified as the composition in a total amount of 100 L. 1 to 40 kg of sugar, preferably 5 to 25 kg, more preferably 7 to 20 kg; sake cake 0.5 to 30 kg, preferably 1 to 15 kg, more preferably 3 to 10 kg; rice koji (dried koji) 0.05 to 10 kg; Preferably 0.1 to 10 kg, more preferably 0.5 to 5 kg; honey 50 to 500 g; ginger 10 to 500 g, preferably 100 to 300 g; plum extract 1 to 100 ml, preferably 5 to 30 ml; , Citric acid, acetic acid, gluconic acid, tartaric acid, fumaric acid, etc.) 1 to 50 g, preferably 2 to 20 g. In addition, sake lees amazake is composed of sugar, sake lees, starch, salt, water, and the like, and its composition is as described above. Even when only sake lees and rice koji are used, the composition and composition may be appropriately defined within the range of the composition ratio of 90:10 to 10:90 based on the above.
[0013]
In order to produce the functional health food or drink according to the present invention, in addition to sake lees and rice koji, the above-mentioned components may be appropriately mixed and stirred as required. In that case, the mixture may be heated. The heating may be carried out in the same manner as in the production of amazake, and for the purpose of promoting saccharification and edibleization of each component, for example, 20 to 80 ° C, preferably 50 to 65 ° C, more preferably around 60 ° C. Is good. In addition, rice grains remain in rice koji, there are cases where rice grains such as glutinous rice remain in amazake, and sake lees and ginger etc. also contain solids, so it is easy to drink by performing grinding treatment It is also possible to do.
[0014]
In addition, the functional health food or drink according to the present invention is further concentrated, pasted, dried, hardened and processed into a jelly, and processed into supplements such as tablets, capsules and drinks. May be formulated. If necessary, a food ingredient, a pharmaceutical ingredient or the like having an anti-obesity, blood lipid improvement, learning and memory improvement, and blood pressure lowering action may be added.
[0015]
The functional health food or drink according to the present invention can be directly consumed or edible, can also be used as a food or drink material, can be added to other food or drink, or can be further cooked. It is possible. At this time, since there is no particular problem in safety, it is sufficient to appropriately ingest an appropriate amount as in the case of commercially available amazake or homemade amazake, and when used as a food material, a normal food material It may be used in the same way as.
[0016]
Thus, the functional health food and drink according to the present invention can be directly eat and drink as anti-obesity food and drink, blood lipid improving food and drink, anti-dementia food and drink, hypotensive food and drink, etc. Can also be used as appropriate. The details of the mechanism by which these functions are obtained must be considered in future studies, but it is thought that active ingredients such as peptides, amino acids, fibers, oligosaccharides, organic acids, polyphenols, and enzymes are acting synergistically. Can be
[0017]
Hereinafter, the present invention will be described in more detail with reference to Examples.
[0018]
Embodiment 1
6 kg of sake lees, 1 kg of rice koji (dried koji), 10 kg of sugar, 1 kg of water syrup, 0.5 kg of honey, 10 kg of acidulant (lactic acid), 200 g of ginger, and water to make 100 L, sufficiently stirred and mixed at a product temperature of 60 ° C. After holding for 10 hours, 195 g was filled into a scale can to produce a health drink. This healthy drink was directly drinkable with or without warming as amazake.
[0019]
Embodiment 2
An experimental system for obesity test was established, and the anti-obesity effect of a health drink (hereinafter, simply referred to as amazake) prepared in a sake lees amazake type containing rice koji produced in Example 1 was evaluated.
[0020]
As a control group, 4-week-old female ICR mice were allowed to freely ingest a high-fat feed (comprising 20% of tallow powder) and tap water. As a result, compared to the blank group in which only CE-2 (the high fat feed) was ingested, the amount of weight gain showed a high value from the 18th day, and the generation of an obese model mouse was confirmed.
[0021]
In the amazake administration group, the solid portion of the amazake was mixed with a high fat feed, and the water-soluble portion was freely ingested as a beverage. The method is as follows. The amazake was centrifuged to separate the precipitate fraction into the supernatant fraction. The precipitate was washed with an equal amount of water and then mixed with a high fat feed so that the dry weight was 10% of the whole. The washing solution after washing the precipitate was collected and combined with the supernatant fraction to give a beverage. Others were tested under the same conditions as the control group.
[0022]
As a result, the body weight gain was significantly suppressed from day 10 as compared with the control group in which only the high fat diet was ingested (p <0.05), and anti-obesity due to the administration of amazake was observed (FIG. 1).
[0023]
Embodiment 3
Using the test system of Example 1, the blood lipid improving effect of amazake was evaluated. In the control group, the blood triglyceride concentration was significantly higher from day 14 (p <0.05) than in the blank group, and the generation of a hyperlipidemic model mouse was confirmed.
[0024]
In the amazake administration group, the blood triglyceride concentration was significantly suppressed from day 14 as compared with the control group (p <0.05), and a blood lipid improving effect was observed (FIG. 2).
[0025]
Embodiment 4
An experimental system for a blood pressure test was established, and the blood pressure lowering effect of amazake was evaluated.
[0026]
As a control group, 4-week-old female ICR mice were allowed to freely ingest high-salt diet (containing 10% salt) and tap water. As a result, compared with the blank group in which only CE-2 (the above-mentioned high salt diet) was taken, the blood pressure showed a higher value from the 19th day, and the creation of a hypertensive model mouse was confirmed.
[0027]
In the amazake administration group, the solid portion of the amazake was mixed with a high-salt feed, and the water-soluble portion was freely ingested as a beverage. The method is the same as in Examples 2 and 3. The test was performed under the same conditions as the control group.
[0028]
As a result, as compared with the control group in which only the high salt diet was taken, the blood pressure showed a low value from the 19th day, and the blood pressure lowering effect by the administration of amazake was observed (FIG. 3).
[0029]
Embodiment 5
An experimental system for learning and memory tests was established, and the effect of amazake on amnesia was evaluated.
[0030]
In the learning and memory test, a platform-type water maze device was used, and the learning and memory ability of the mouse was evaluated based on the time to reach the platform. The mice used were ICR female 9 weeks old. As an acquisition trial, mice were allowed to swim twice a day for 5 consecutive days, and mice were allowed to learn the position of the platform. As a result, the arrival time was shortened and converged to a substantially constant value.
[0031]
As a control group, physiological saline (20 ml / kg) was orally administered by gavage to a mouse immediately after the acquisition trial was completed. After 60 minutes, scopolamine (2 mg / kg) was administered subcutaneously and a test trial was performed 30 minutes later. As a result, the arrival time was significantly prolonged (p <0.05) compared to that before scopolamine administration,
The creation of an amnesia model mouse was confirmed.
[0032]
In the amazake administration group, amazake (20 ml / kg) was orally administered by gavage to the mouse immediately after the end of the acquisition trial. After a lapse of 60 minutes, scopolamine administration and test trial were performed in the same manner as in the control group. As a result, the arrival time was suppressed (p <0.05) as compared with the test trial of the control group, and the amnesia-suppressing effect of amazake was observed (FIG. 4).
[0033]
Embodiment 6
After adding 20 kg of water to 10 kg of glutinous rice and boiled, cool to 70 ° C., add 10 kg of rice koji, mix well, hold at 55 to 60 ° C. for 2 days and saccharify, then add and mix 50 kg of sake lees. Manufactured functional health drinks.
[0034]
【The invention's effect】
The novel functional health food and drink according to the present invention has excellent anti-obesity effect, blood lipid improving effect, learning memory improving effect, and blood pressure lowering effect, and is useful for prevention, suppression, improvement and treatment of these pathological conditions. is there. In addition, the health food and drink are very characteristic in that there is no problem with regard to safety and that they have all of the above-mentioned actions instead of one. Therefore, it is suitable to be taken on a daily basis, especially for patients with lifestyle-related diseases and their prevention.
[Brief description of the drawings]
FIG. 1 shows the suppressive effect on obesity of the functional health food or drink according to the present invention. Note that BK indicates a blank and CONT indicates a control. same as below.
FIG. 2 shows the inhibitory effect on hyperlipidemia.
FIG. 3 shows an inhibitory effect on hypertension.
FIG. 4 also shows the inhibitory effect on amnesia.

Claims (6)

A functional health food or drink comprising only sake lees and rice koji. A functional health food or drink comprising sake lees and rice koji, and further comprising at least one selected from a seasoning component, a flavoring component, a coloring component, and water. The functional health food or drink according to claim 1 or 2, wherein the seasoning component is at least one of a sweetener, an acidulant, and salt. The functional health food or drink according to any one of claims 1 to 3, wherein the content ratio of sake lees and rice koji is 90:10 to 10:90. The functional food or drink according to any one of claims 1 to 4, wherein the food or drink is a health drink. The functional health according to any one of claims 1 to 5, wherein the functionality is at least one selected from anti-obesity, blood lipid improving property, blood pressure lowering property, and amnesia suppressing property. Food and drink.

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