JP2004256785A - Soap containing gammalinolenic acid and fine powder of calcined shell - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a soap which has a auxiliary therapeutic effect for calming down an itching caused by an atopic dermatitis lesion, a psoriasis lesion and a kidney dialysis and also has an antimicrobial effect to suppress a yellow staphylococcus which propagates at a diseased part, and also to provide a soap which has a depression effect for a tinea pedis (athlete's foot) caused by breeding of a true fungus. <P>SOLUTION: The soap is produced by adding in a proper quantity to a soap made from a natural fatty oil a gammalinolenic acid, which is contained in a borage oil and an evening primrose oil and is expected to have a pruritus silencing effect, and a fine powder prepared by high temperature calcination of shells of a scallop, an oyster, a surf clam, etc. which is expected to have an environmentally friendly antimicrobial activity.The use of the soap reduces an economical burden of users and also exhibits a pruritous suppression effect of a transdermally soaked gammalinolenic acid in a daily bathing time indispensable in daily life of an atopic dermatitis patient as well as exhibits an antimicrobial activity to suppress the propagation of a true fungus such as an yellow staphylococcus which propagates at a skin surface. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a soap having the pruritus-suppressing effect of gamma lenolinic acid and the antibacterial effect of fired shell powder in addition to the cleaning power of soap.
[0002]
[Prior art]
Soaps containing a substance intended to alleviate skin pruritus in addition to the cleaning effect of soap are not commercially available. However, so-called medicated soaps which have been imparted with antibacterial properties by incorporating antibacterial substances such as icutamol and chlorhexidine hydrochloride obtained from synthetic chemistry have been manufactured and sold.
[0003]
[Problems to be solved by the invention]
It is necessary to use a safe substance for the purpose of pruritus relief to reach skin tissue by using soap. On the other hand, antibacterial agents such as icutamol and chlorhexidine hydrochloride are used as antibacterial agents to suppress the growth of Staphylococcus aureus and fungi. There are concerns about the impact on ecosystems in rivers and lakes. By replacing this with a natural antibacterial substance, the significance of reducing the environmental load can be obtained.
[0004]
[Means to solve the problem]
Gamma renolinic acid is also produced in the body, and is produced from ingested foods by a desaturating enzyme called D6D (delta 6 desastase) which is a physiological substance provided in the body. Has been confirmed. On the other hand, it has been confirmed that gamma renolinic acid has a function of inhibiting the synthesis of interleukin 1 and interleukin 2 among cytokines involved in the inflammatory response causing pruritus or tumor necrosis factor. The inhibitory effect of this gamma renolinic acid suggests an effect of suppressing inflammation and pruritus. Therefore, as a method of supplementing gamma lenolinic acid from the outside, which is expected to have the effect of suppressing inflammation and pruritus, it reaches the dermis layer by percutaneous absorption through the use of soap containing evening primrose oil or borage oil containing a large amount of gamma renolinic acid Then, a method of leaving soap residue on the skin surface after washing was adopted.
Furthermore, if an appropriate amount of shell fired fine powder such as scallops, oysters, and mussels is mixed in soap to obtain an antibacterial effect, an effect comparable to an antibacterial agent of a synthetic chemical substance can be obtained.
[0005]
【The invention's effect】
Conventionally, gamma renolinic acid has been orally ingested for the purpose of alleviating pruritus in skin diseases under the guidance of some physicians. In addition, although a method of directly applying it to the skin has also been performed, the effect on the economic burden is unknown, and there is no antibacterial effect on the skin surface.
The soap of the present invention reduces the economic burden and provides a pruritus-inhibiting effect by periodically and quantitatively transcutaneously absorbing gamma-renolinic acid during daily bathing, which is essential for the daily life of atopic dermatitis patients. In addition, it also provides an antibacterial effect that suppresses the propagation of Staphylococcus aureus and fungi that propagate on the skin surface, assists in the treatment of various skin diseases such as atopic dermatitis, improves symptoms, and alleviates symptoms I want to spread the significance of the present invention.

Claims (3)

A solid or liquid soap containing gamma lenolinic acid and fired shell fine powder as active ingredients. 2. The soap according to claim 1, wherein gamma lenolinic acid contained in evening primrose oil or borage oil is contained in a range of 0.1% to 5% by weight. 2. The soap according to claim 1, which contains a shell-fired fine powder obtained from bivalves such as scallop, oysters, clams, and conch shells such as turban shellfish in a weight ratio of 0.01% to 10%.