GB2482526A - Praziquantel suspendable powder as an immersion fish treatment for parasites - Google Patents
Praziquantel suspendable powder as an immersion fish treatment for parasites Download PDFInfo
- Publication number
- GB2482526A GB2482526A GB1013181.1A GB201013181A GB2482526A GB 2482526 A GB2482526 A GB 2482526A GB 201013181 A GB201013181 A GB 201013181A GB 2482526 A GB2482526 A GB 2482526A
- Authority
- GB
- United Kingdom
- Prior art keywords
- praziquantel
- powder
- parasites
- fish
- suspendable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
- A01N25/14—Powders or granules wettable
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Abstract
A method of formulating and using praziquantel in a suspendable powder for the immersion treatment of fish in ponds or tanks for external parasites. A suspendable powder is also claimed comprising a combination of praziquantel as the active ingredient with an inert powder, surfactant or surfactants and dispersing agent or agents. The inert powder may be silicon dioxide. The surfactant may be sodium lauryl sulfate and the dispersing agent may be sodium naphthalene sulfonate formaldehyde condensate.
Description
Description Title
A method of formulating praziquantel to make it suitable as an immersion treatment for fish parasites
Background
Ornamental fish can suffer from a range of diseases including external and internal parasites.
Treatment of ornamental fish in ponds or tanks can present a range of challenges since they often cannot be handled and treated individually, administering medications in the feed is difficult since they may vary in appetite, and in general fish which are feeling ill do not eat as well as healthy fish, despite being the ones who need the treatment. Also mixing the medication with the fish feed can present its own problems since the challenge is to make the medication stick to the feed and not wash off into the pond or tank water before the food is consumed. The other problem here is that there is no guarantee with the oral route that fish will consume a therapeutic dose of the medicine which could in time lead to the parasites developing resistance to the product.
Treatment of disease problems by immersing the fish in the medicine can be a better way of treating them, but there are a number of problems associated with this method -the medicinal product most be efficacious, readily soluble and disperse rapidly through the water, it must be safe for the fish and other pondlife, and it must not have an adverse effect on the biofllters which are an essential part of the running of a pond or tank system. Otherwise it has to be dissolved in solvents which may themselves present health risks both to the fish and to the humans working with them.
Statement of invention
Praziquantel, although an effective treatment for fish parasites, is only slightly soluble in water, and this invention is a method of formulating praziquantel in a suspendable powder which allows it to dissolve at the treatment dose by evenly dispersing it throughout the pond or tank water.
Advantages The advantage of this method of formulating praziquantel is that all the fish in a pond or tank can be easily treated with a scientifically proven therapeutic, without having to dissolve it in solvents first, or trying to incorporate it into feed and getting the fish to consume a therapeutic dose. The other advantage is that the finished product is stable, and so can be stored for extended periods, and is in a presentation which is easy to use straight from the packet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1013181.1A GB2482526A (en) | 2010-08-05 | 2010-08-05 | Praziquantel suspendable powder as an immersion fish treatment for parasites |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1013181.1A GB2482526A (en) | 2010-08-05 | 2010-08-05 | Praziquantel suspendable powder as an immersion fish treatment for parasites |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB201013181D0 GB201013181D0 (en) | 2010-09-22 |
| GB2482526A true GB2482526A (en) | 2012-02-08 |
Family
ID=42931236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1013181.1A Withdrawn GB2482526A (en) | 2010-08-05 | 2010-08-05 | Praziquantel suspendable powder as an immersion fish treatment for parasites |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2482526A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999018796A2 (en) * | 1997-10-09 | 1999-04-22 | Rhone-Poulenc Agro | Pesticidal combination |
| WO2009062939A1 (en) * | 2007-11-15 | 2009-05-22 | Novartis Ag | Anthelmintic paste comprising praziquantel, a macrolide lactone, cyclodextrin and a thickener |
| CN101838268A (en) * | 2010-04-30 | 2010-09-22 | 孙德群 | Pyroquine pesticide and application thereof |
| WO2011027333A1 (en) * | 2009-09-07 | 2011-03-10 | Douglas Robert Cleverly | Granulated anthelmintic preparations and delivery systems |
-
2010
- 2010-08-05 GB GB1013181.1A patent/GB2482526A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999018796A2 (en) * | 1997-10-09 | 1999-04-22 | Rhone-Poulenc Agro | Pesticidal combination |
| WO2009062939A1 (en) * | 2007-11-15 | 2009-05-22 | Novartis Ag | Anthelmintic paste comprising praziquantel, a macrolide lactone, cyclodextrin and a thickener |
| WO2011027333A1 (en) * | 2009-09-07 | 2011-03-10 | Douglas Robert Cleverly | Granulated anthelmintic preparations and delivery systems |
| CN101838268A (en) * | 2010-04-30 | 2010-09-22 | 孙德群 | Pyroquine pesticide and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| GB201013181D0 (en) | 2010-09-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |