JP2004250456A - Dentifrice - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To easily produce a low-cost dentifrice by compounding granules using no binder into the dentifrice. <P>SOLUTION: This dentifrice contains wet-method silica granules with such a granular size that the granules pass through a 30-mesh sieve but does not pass through a 200-mesh sieve. The silica granules have a breaking strength per granule of 30-800 gf/mm<SP>2</SP>and a grinding force with a RDA (radioactive dentine abrasion) value of ≤150. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

  The present invention relates to a dentifrice containing wet-processed silica granules, and more specifically, an aesthetic effect of the granules and a touch of the granules in the oral cavity so that the effect of removing dirt can be recognized, and the granules have such strength as to be perceptible in the oral cavity. The present invention relates to a dentifrice that does not give an unpleasant foreign body sensation because it gradually disintegrates in the process of dentifrice, despite having such a size.

  Dentifrices containing granules or granular substances have been conventionally known. Such granules include those containing a functional material such as a drug, an enzyme agent, and an abrasive, and those intended for the aesthetic effect thereof. As a binder for these granules, a water-soluble binder such as methylcellulose and carboxymethylcellulose and a water-insoluble binder such as wax and ethylcellulose have been used. In addition, there are problems such as the disintegration of the granules, and when the above water-insoluble binder is used, if the hardness and size of the granules are adjusted to the extent that they can be perceived, the granules are perceived as foreign matter in the oral cavity And other problems.

Accordingly, the present applicant has proposed a dentifrice containing granules obtained by binding a water-insoluble powder material such as zeolite with a water-insoluble inorganic binder as a dentifrice that has solved the above problems (Patent Documents) 1). This dentifrice is made by granulating a water-insoluble powder material with a water-insoluble binder and blending granules having a certain size and strength, so that the granules can be palpated in the oral cavity and the effect can be recognized. Nevertheless, the abrasive force is enhanced without substantially feeling the foreign substance sensation and without damaging the teeth.
JP-A-1-299211

However, there is a problem that the granules contained in the dentifrice are expensive because a binder is required for the production.
Therefore, there is a need for a dentifrice that incorporates granules produced without using a binder and has the same or better performance as the above dentifrice.

  Under such circumstances, the present inventors have conducted intensive studies and as a result, the wet process silica can be made into granules without a binder, and the dentifrice containing the granules can palpate the granules in the oral cavity, Despite recognizing the effect, the inventor found that the feeling of foreign matter was hardly felt and the polishing power was enhanced without damaging the teeth, and the present invention was completed.

That is, the present invention has a particle size that passes through a 30-mesh sieve (JIS standard) but does not pass through a 200-mesh sieve (JIS standard), and has a collapse strength per unit of 30 to 800 gf / mm ² . Another object of the present invention is to provide a dentifrice containing wet-processed silica granules having an abrasive force of 150 or less in RDA value.

  The wet-processed silica granules used in the present invention need to have a particle size (75 to 500 μm) that passes through a 30-mesh sieve but does not pass through a 200-mesh sieve. A particle size of 75 μm or more is required to be visually perceived and palpable in the oral cavity. Further, the average particle size is preferably 150 to 250 μm.

Strength of the wet process silica granules (hardness) is a strength decay in granular per 30~800gf / mm ^2, particularly preferably 40~500gf / mm ^2. If the disintegration strength per silica granule is less than 30 gf / mm ² , the abrasive power is not sufficient, and if it exceeds 800 gf / mm ² , it is felt only as a foreign substance and does not disintegrate by brushing at all. May damage the enamel.

  The polishing power of the wet silica granules needs to be 150 or less, particularly preferably 100 or less, RDA value (Radioactive Dentine Abrasion values). If the RDA value exceeds 150, the teeth may be cut more than necessary.

The specific surface area and pore volume according to the BET method of the wet silica granules are 150 to 450 m ² / g and 1 to 2.5 ml / g, respectively, for controlling the disintegration strength of the granules, the medicinal component and the amount of adsorption of the fragrance. It is particularly preferably 200 to 400 m ² / g and 1.5 to 2.0 ml / g.

  The wet silica used in the present invention can be produced by a precipitation method or a gel method, for example, according to the following production method.

(1) A method in which a silica hydrosol whose pH has been adjusted in advance is suspended in a medium such as an incompatible oil, solidified in the suspension, and impurities are washed and removed, followed by drying. .
(2) A method in which a silica hydrosol is sprayed into the air to form a gel, impurities are removed by washing, and then drying is performed.

  The wet-processed silica granules incorporated in the dentifrice of the present invention may be obtained by any of these methods.

The wet-processed silica granules thus obtained can be blended with various dentifrices such as toothpastes and powdered dentifrices, but it is particularly preferable to blend them with toothpastes in order to express the aesthetics of the granules.
The content of the granules is preferably 1 to 50% by weight, particularly preferably 3 to 30% by weight in the dentifrice.

  Since silica has a large specific surface area, by mixing a medicinal component or a fragrance into wet-process silica granules and blending it into a dentifrice, silica fragments that have collapsed during tooth brushing can be adsorbed and remain in the oral cavity. Can be released slowly.

  The medicinal component is not particularly limited as long as it is used in the oral region, and examples thereof include a caries preventive agent, an antimicrobial agent, a vitamin, an enzyme, an anti-inflammatory agent, and the like. Sodium fluoride, tin fluoride, sodium monofluorophosphate, vitamin E, vitamin C, dextranase, mutanase, sodium chloride, glycyrrhetinic acid, azulene, β-glycyrrhetinic acid, dihydrocholesterol, chlorhexidine, epidihydrocholesterol, Examples thereof include isopropylmethylphenol, trichlorocarbanilide, halocarban, hinokitiol, allantoin, tranexamic acid, propolis, cetylpyridinium chloride, and the like, and these can be used alone or in combination of two or more.

  Examples of fragrances include menthol and natural products containing menthol; basil, camphor, caraway, cardamom, coriander, geranium, ginger, laurel, lavender, mace, nutmeg, pepper, rose, rosemary, thyme, ylang ylang, jasmine. Essential oils and extracts of vanilla, hyssop, lavandin, oris, carrot seed, dabana, eremi, osmantas; borneol and its derivatives; heliotropin; α-, β-, γ-, δ-ionone and their derivatives; thymol, Examples thereof include vanillin, ethyl vanillin, maltol, and ethyl maltol, and these can be used alone or in combination of two or more.

  Preparation of the dentifrice of the present invention is carried out according to a conventional method, and other components which are added to a usual dentifrice can be added. Examples of the binder include sodium carboxymethylcellulose, sodium polyacrylate, hydroxyethylcellulose, thickening silica, montmorillonite, carrageenan, sodium alginate, guar gum, pectin, and the like. Examples of the surfactant include salts of acyl amino acids such as sodium acylglutamate and sodium acylsarcosine; salts of alkyl phosphoric acids such as sodium lauryl phosphate; sucrose fatty acid esters, sorbitan fatty acid esters, polyoxyethylene fatty acid esters, and polyoxyethylene. And polyoxypropylene block copolymers. In addition, the same medicinal components and flavors, humectants, sweeteners, preservatives, and the like as described above can be added.

  Since the granules contained in the dentifrice of the present invention do not use a binder, they can be easily manufactured at low cost and have an advantage that the cost of the dentifrice can be reduced.

  Next, the present invention will be described with reference to examples, but the present invention is not limited to these examples.

Example 1
A silica hydrosol having a primary particle size of 4.0 nm was sprayed into the air to gel, washed with purified water, and dried to produce wet-process silica granules.

The resulting granules have a particle size (average particle size 200 μm) that passes through a 30 mesh sieve but does not pass through a 200 mesh sieve, disintegrates when a load of 200 gf / mm ² is applied, and the abrasive power is RDA The value was 60, the specific surface area was 280 m ² / g, and the pore volume was 1.90 ml / g.

  To evaluate the feel of the granules, the produced granules were directly blended into a dentifrice having the composition shown in Table 1. The dentifrice was left for one week after production for stabilization of the fragrance. Thereafter, 20 panelists were asked to use this dentifrice, and immediately afterwards, the feel of the granules was evaluated. A normal round cut toothbrush was used as the toothbrush. The degree of recognition of the granules in the oral cavity and the feel of the granules were classified as follows. The feel of the granules was evaluated by a panelist who recognized the granules in the oral cavity. Table 2 shows the results.

(Recognition of granules in the oral cavity):
1; Recognized from the start of brushing until the end of brushing.
2: Granules were palpable at the beginning of brushing, but could not be felt during brushing.
3: The granules could not be palpated.

(Granular feel):
1; good.
2; somewhat good.
3: Neither.
4: Somewhat bad.
5; bad.

Test Example Dentifrice (comparative product) in which 15.0% by weight of wet-process silica having a particle size of 10 μm was blended instead of the wet-process silica granules in the dentifrice shown in Table 1 (the present invention) and the dentifrice shown in Table 1 ) Was tested for cleaning action. 1 g of dentifrice was applied to a glass plate coated with black magic ink and brushed, and the number of times of brushing when the magic sink on the glass plate was completely removed with the naked eye (when the test was performed 10 times) Average). The number of times of brushing was 4.7 for the product of the present invention and 30.5 for the comparative product.

Examples 2 to 4
Silica granules having the properties shown in Table 3 below were obtained, and a toothpaste having the composition shown in Table 4 was prepared. These toothpastes were good in both feel and cleansing action.

Claims (5)

Wet silica granules having a particle size that passes through a 30-mesh sieve but does not pass through a 200-mesh sieve, have a disintegration strength of 30 to 800 gf / mm ² , and have an abrasive power of 150 or less RDA value. Dentifrice containing. Dentifrice according to claim 1, wherein a BET specific surface area of the wet silica granules is 150~450m ² / g.   The dentifrice according to claim 1 or 2, wherein the pore volume of the wet process silica granules is 1 to 2.5 ml / g.   The dentifrice according to any one of claims 1 to 3, wherein the content of the wet-process silica granules is 1 to 30% by weight.   The dentifrice according to any one of claims 1 to 4, wherein the wet method silica granules are synthesized by a precipitation method or a gel method.