JP2004248669A5 - - Google Patents

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Publication number
JP2004248669A5
JP2004248669A5 JP2004015978A JP2004015978A JP2004248669A5 JP 2004248669 A5 JP2004248669 A5 JP 2004248669A5 JP 2004015978 A JP2004015978 A JP 2004015978A JP 2004015978 A JP2004015978 A JP 2004015978A JP 2004248669 A5 JP2004248669 A5 JP 2004248669A5
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Japan
Prior art keywords
lysine
methylophilus
bacterium
enhanced
producing
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JP2004015978A
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Japanese (ja)
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JP2004248669A (en
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Priority to JP2004015978A priority Critical patent/JP2004248669A/en
Priority claimed from JP2004015978A external-priority patent/JP2004248669A/en
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Publication of JP2004248669A5 publication Critical patent/JP2004248669A5/ja
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Claims (7)

生育にL−メチオニンを要求し、かつ、L−リジン生産能を有するメタノール資化性細菌を、メタノールを主要炭素源とする培地に培養し、培養物中にL−リジンを生産蓄積させ、該培養物からL−リジンを採取することを特徴とするL−リジンの製造法。   Methanol assimilating bacteria that require L-methionine for growth and have L-lysine-producing ability are cultured in a medium containing methanol as a main carbon source, and L-lysine is produced and accumulated in the culture. A method for producing L-lysine, which comprises collecting L-lysine from a culture. メタノール資化性細菌がメチロフィラス属細菌である請求項1に記載のL−リジンの製造法。   The method for producing L-lysine according to claim 1, wherein the methanol-assimilating bacterium is a genus Methylophilus. メチロフィラス属細菌がメチロフィラス・メチロトロファスである請求項2に記載のL−リジンの製造法。   The method for producing L-lysine according to claim 2, wherein the Methylophilus bacterium is Methylophilus methylotrophus. メチロフィラス属細菌が、ジヒドロジピコリン酸合成酵素活性が増強され、かつ、L−リジン排出系が増強されるように改変されている請求項1〜3のいずれか一項に記載のL−リジンの製造法。 The L-lysine production according to any one of claims 1 to 3, wherein the Methylophilus bacterium is modified so that dihydrodipicolinate synthase activity is enhanced and the L-lysine excretion system is enhanced. Law. 生育にL−メチオニンを要求し、かつ、L−リジン生産能を有するメチロフィラス属細菌。   A Methylophilus bacterium that requires L-methionine for growth and has an ability to produce L-lysine. メチロフィラス・メチロトロファスである請求項5に記載のメチロフィラス属細菌。   6. The bacterium belonging to the genus Methylophilus according to claim 5, which is Methylophilus methylotrophus. ジヒドロジピコリン酸合成酵素活性が増強され、かつ、L−リジン排出系が増強されるように改変されている請求項5又は6に記載のメチロフィラス属細菌。 The bacterium belonging to the genus Methylophilus according to claim 5 or 6, which is modified so that dihydrodipicolinate synthase activity is enhanced and L-lysine excretion system is enhanced.
JP2004015978A 2003-01-29 2004-01-23 Method for preparing l-lysine using methanol assimilating bacteria Withdrawn JP2004248669A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2004015978A JP2004248669A (en) 2003-01-29 2004-01-23 Method for preparing l-lysine using methanol assimilating bacteria

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003020513 2003-01-29
JP2004015978A JP2004248669A (en) 2003-01-29 2004-01-23 Method for preparing l-lysine using methanol assimilating bacteria

Publications (2)

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JP2004248669A JP2004248669A (en) 2004-09-09
JP2004248669A5 true JP2004248669A5 (en) 2005-11-04

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JP2004015978A Withdrawn JP2004248669A (en) 2003-01-29 2004-01-23 Method for preparing l-lysine using methanol assimilating bacteria

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009153382A (en) 2006-03-30 2009-07-16 Ajinomoto Co Inc Method for producing carboxylic acid using methanol-assimilating bacterium
KR102139806B1 (en) * 2020-02-13 2020-07-30 씨제이제일제당 (주) Microorganism Comprising Mutated LysE and Method of L-Amino Acid Production Using the Same

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