JP2004238622A - 変更された結晶構造を有する急速膨張性澱粉 - Google Patents
変更された結晶構造を有する急速膨張性澱粉 Download PDFInfo
- Publication number
- JP2004238622A JP2004238622A JP2004023233A JP2004023233A JP2004238622A JP 2004238622 A JP2004238622 A JP 2004238622A JP 2004023233 A JP2004023233 A JP 2004023233A JP 2004023233 A JP2004023233 A JP 2004023233A JP 2004238622 A JP2004238622 A JP 2004238622A
- Authority
- JP
- Japan
- Prior art keywords
- starch
- water
- birefringence
- tablet
- particle size
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920002472 Starch Polymers 0.000 title claims abstract description 132
- 235000019698 starch Nutrition 0.000 title claims abstract description 132
- 239000008107 starch Substances 0.000 title claims abstract description 118
- 239000013078 crystal Substances 0.000 title description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 55
- 230000008961 swelling Effects 0.000 claims abstract description 29
- 239000007885 tablet disintegrant Substances 0.000 claims abstract description 4
- 239000007884 disintegrant Substances 0.000 claims description 27
- 239000002245 particle Substances 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 16
- 150000003839 salts Chemical class 0.000 claims description 12
- 239000002195 soluble material Substances 0.000 claims description 8
- 229920000881 Modified starch Polymers 0.000 claims description 5
- 235000019426 modified starch Nutrition 0.000 claims description 5
- 239000004368 Modified starch Substances 0.000 claims description 2
- 239000012530 fluid Substances 0.000 abstract description 9
- 239000000463 material Substances 0.000 abstract description 3
- 229940032147 starch Drugs 0.000 description 104
- 238000000034 method Methods 0.000 description 27
- 230000008569 process Effects 0.000 description 18
- 239000002002 slurry Substances 0.000 description 18
- 230000005764 inhibitory process Effects 0.000 description 17
- 239000008187 granular material Substances 0.000 description 16
- 235000002639 sodium chloride Nutrition 0.000 description 14
- 238000001694 spray drying Methods 0.000 description 14
- 239000000126 substance Substances 0.000 description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 10
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 description 10
- 229920001592 potato starch Polymers 0.000 description 10
- 239000007787 solid Substances 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 230000036571 hydration Effects 0.000 description 8
- 238000006703 hydration reaction Methods 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 239000002904 solvent Substances 0.000 description 8
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 244000061456 Solanum tuberosum Species 0.000 description 6
- 235000002595 Solanum tuberosum Nutrition 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 5
- 238000010411 cooking Methods 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 239000011780 sodium chloride Substances 0.000 description 5
- 239000007921 spray Substances 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000006266 etherification reaction Methods 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 230000036961 partial effect Effects 0.000 description 4
- 239000012266 salt solution Substances 0.000 description 4
- UGTZMIPZNRIWHX-UHFFFAOYSA-K sodium trimetaphosphate Chemical compound [Na+].[Na+].[Na+].[O-]P1(=O)OP([O-])(=O)OP([O-])(=O)O1 UGTZMIPZNRIWHX-UHFFFAOYSA-K 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 229920000856 Amylose Polymers 0.000 description 3
- 235000000378 Caryota urens Nutrition 0.000 description 3
- 240000000163 Cycas revoluta Species 0.000 description 3
- 235000008601 Cycas revoluta Nutrition 0.000 description 3
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 3
- 240000003183 Manihot esculenta Species 0.000 description 3
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 description 3
- 235000010103 Metroxylon rumphii Nutrition 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 235000021307 Triticum Nutrition 0.000 description 3
- 244000098338 Triticum aestivum Species 0.000 description 3
- 240000008042 Zea mays Species 0.000 description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 3
- 238000007605 air drying Methods 0.000 description 3
- 235000005822 corn Nutrition 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 235000013312 flour Nutrition 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 description 3
- 235000011152 sodium sulphate Nutrition 0.000 description 3
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 239000012736 aqueous medium Substances 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000007907 direct compression Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- LEQAOMBKQFMDFZ-UHFFFAOYSA-N glyoxal Chemical compound O=CC=O LEQAOMBKQFMDFZ-UHFFFAOYSA-N 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000000314 lubricant Substances 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 238000000386 microscopy Methods 0.000 description 2
- 239000002480 mineral oil Substances 0.000 description 2
- 235000010446 mineral oil Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 238000007873 sieving Methods 0.000 description 2
- 238000007614 solvation Methods 0.000 description 2
- 238000005550 wet granulation Methods 0.000 description 2
- 240000001592 Amaranthus caudatus Species 0.000 description 1
- 235000009328 Amaranthus caudatus Nutrition 0.000 description 1
- 229920000945 Amylopectin Polymers 0.000 description 1
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 244000075850 Avena orientalis Species 0.000 description 1
- 235000005273 Canna coccinea Nutrition 0.000 description 1
- 240000008555 Canna flaccida Species 0.000 description 1
- 239000004971 Cross linker Substances 0.000 description 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 244000027321 Lychnis chalcedonica Species 0.000 description 1
- 235000010804 Maranta arundinacea Nutrition 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 240000004713 Pisum sativum Species 0.000 description 1
- 235000010582 Pisum sativum Nutrition 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 240000003829 Sorghum propinquum Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 244000145580 Thalia geniculata Species 0.000 description 1
- 235000012419 Thalia geniculata Nutrition 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 235000012735 amaranth Nutrition 0.000 description 1
- 239000004178 amaranth Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000001212 derivatisation Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000004211 gastric acid Anatomy 0.000 description 1
- 229940015043 glyoxal Drugs 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000012457 nonaqueous media Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 238000001907 polarising light microscopy Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/003—Crosslinking of starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/003—Crosslinking of starch
- C08B31/006—Crosslinking of derivatives of starch
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/354,714 US6846497B2 (en) | 2003-01-30 | 2003-01-30 | Rapidly expanding starches with altered crystalline structure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004238622A true JP2004238622A (ja) | 2004-08-26 |
| JP2004238622A5 JP2004238622A5 (https=) | 2007-03-15 |
Family
ID=32655558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004023233A Pending JP2004238622A (ja) | 2003-01-30 | 2004-01-30 | 変更された結晶構造を有する急速膨張性澱粉 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6846497B2 (https=) |
| EP (1) | EP1443057B1 (https=) |
| JP (1) | JP2004238622A (https=) |
| AT (1) | ATE348114T1 (https=) |
| DE (1) | DE602004003599T2 (https=) |
| ES (1) | ES2276175T3 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009123102A1 (ja) | 2008-03-31 | 2009-10-08 | 旭化成ケミカルズ株式会社 | 崩壊性に優れる加工澱粉粉末及びその製法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7462861B2 (en) * | 2004-04-28 | 2008-12-09 | Cree, Inc. | LED bonding structures and methods of fabricating LED bonding structures |
| US8871270B2 (en) | 2004-07-09 | 2014-10-28 | Corn Products Development, Inc | Tablet excipient |
| PL1861427T3 (pl) * | 2005-03-23 | 2013-01-31 | Bpsi Holdings Llc | Kompozycje aglomerowanej skrobi |
| US20070054027A1 (en) * | 2005-09-08 | 2007-03-08 | Eric Weisser | Starch hydrolysis products for size enlargement |
| CN101677945A (zh) * | 2007-05-08 | 2010-03-24 | 赫尔克里士公司 | 坚固的快速崩解片剂制剂 |
| US20090311408A1 (en) * | 2008-06-17 | 2009-12-17 | Brunob Ii B.V. | Low swelling starch |
| US10463066B2 (en) | 2012-05-15 | 2019-11-05 | Tate & Lyle Ingredients Americas Llc | Process for preparing inhibited non-pregelatinized granular starches |
| CN103265729A (zh) * | 2013-05-22 | 2013-08-28 | 苏州志向纺织科研股份有限公司 | 一种光可降解烯烃聚合物的光敏剂合成方法 |
Citations (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS49125488A (https=) * | 1972-12-21 | 1974-11-30 | ||
| JPS575700A (en) * | 1980-06-12 | 1982-01-12 | Asahi Chemical Ind | Processed starch |
| JPS5818322A (ja) * | 1981-07-24 | 1983-02-02 | ナシヨナル・スタ−チ・アンド・ケミカル・コ−ポレイシヨン | 錠剤崩壊剤及びその製造法 |
| JPS5934872A (ja) * | 1982-08-18 | 1984-02-25 | Nichiden Kagaku Kk | 水産練製品の製造方法 |
| JPS59108001A (ja) * | 1982-11-19 | 1984-06-22 | エ−，イ−，ステ−リ−，マニユフアクチユアリング，カンパニ− | 低下したペ−スト化温度を有する顆粒状デンプンエ−テル |
| JPS61112091A (ja) * | 1984-08-17 | 1986-05-30 | ナシヨナル・スタ−チ・アンド・ケミカル・コ−ポレイシヨン | 多糖類誘導体、このものの製造および紙添加材料としての利用 |
| JPH0923826A (ja) * | 1995-07-07 | 1997-01-28 | Nichiden Kagaku Kk | 食品用変性澱粉およびそれを用いたペースト状食品 |
| JPH107842A (ja) * | 1996-03-22 | 1998-01-13 | Natl Starch & Chem Investment Holding Corp | ヒドロキシプロピル化架橋ワキシーポテトスターチ |
| JPH1080294A (ja) * | 1996-05-06 | 1998-03-31 | Natl Starch & Chem Investment Holding Corp | 酵素転換デンプンの調製のための高固形分単相工程 |
| JP2000178182A (ja) * | 1998-12-17 | 2000-06-27 | Lion Corp | 崩壊性組成物 |
| WO2000071117A1 (en) * | 1999-05-21 | 2000-11-30 | Kissei Pharmaceutical Co., Ltd. | Immediate release medicinal compositions for oral use |
| US6299907B1 (en) * | 1998-06-12 | 2001-10-09 | Kansas State University Research Foundation | Reversibly swellable starch products |
| WO2002000204A1 (en) * | 2000-06-23 | 2002-01-03 | Teva Pharmaceutical Industries Ltd. | Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates |
| WO2002002084A1 (en) * | 2000-06-29 | 2002-01-10 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
| JP2002193792A (ja) * | 2000-12-25 | 2002-07-10 | Lion Corp | フィルムコーティング錠剤及びエロージョン防止組成物 |
| JP2002534991A (ja) * | 1999-01-29 | 2002-10-22 | コーオペラティーベ、ベルコープ‐アン、プロドゥクティーベレニギング、バン、アルダペルメール、アン、デリバーテン、アベベ、ベー．アー． | ゼラチン代替物として適した架橋スターチおよび解重合スターチをベースにした組成物 |
| WO2002088188A1 (en) * | 2001-04-26 | 2002-11-07 | Cooperatieve Verkoop-En Productievereniging Van Aardappelmeel En Derivaten Avebe B.A. | Cross-linking of starch |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3034911A (en) | 1959-03-25 | 1962-05-15 | Nat Starch Chem Corp | Tablet disintegrants |
| US3490742A (en) | 1966-01-14 | 1970-01-20 | Staley Mfg Co A E | Compressed tablets |
| US3622677A (en) | 1969-07-07 | 1971-11-23 | Staley Mfg Co A E | Compressed tablets containing compacted starch as binder-disintegrant ingredient |
| US5468286A (en) | 1989-10-25 | 1995-11-21 | National Starch And Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
| US5616343A (en) | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
| US5932017A (en) * | 1993-07-30 | 1999-08-03 | National Starch And Chemical Investment Holding Corporation | Thermally-inhibited non-pregelatinized granular starches and flours and process for their preparation |
| US5830884A (en) | 1995-01-18 | 1998-11-03 | National Starch And Chemical Investment Holding Corporation | Pharmaceutical products containing thermally-inhibited starches |
| AU4700996A (en) | 1995-01-18 | 1996-08-07 | National Starch And Chemical Investment Holding Corporation | Pharmaceutical products containing thermally-inhibited starches |
| US5807575A (en) * | 1997-02-14 | 1998-09-15 | Rougier Inc. | Manufacture of cross-linked amylose useful as a excipient for control release of active compounds |
| GB9802201D0 (en) | 1998-02-03 | 1998-04-01 | Cerestar Holding Bv | Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules |
| FR2801888B1 (fr) | 1999-12-07 | 2002-02-15 | Roquette Freres | Composition diluante et desintegrante, son procede d'obtention et son utilisation |
-
2003
- 2003-01-30 US US10/354,714 patent/US6846497B2/en not_active Expired - Lifetime
-
2004
- 2004-01-29 ES ES04001959T patent/ES2276175T3/es not_active Expired - Lifetime
- 2004-01-29 AT AT04001959T patent/ATE348114T1/de not_active IP Right Cessation
- 2004-01-29 EP EP04001959A patent/EP1443057B1/en not_active Expired - Lifetime
- 2004-01-29 DE DE602004003599T patent/DE602004003599T2/de not_active Expired - Lifetime
- 2004-01-30 JP JP2004023233A patent/JP2004238622A/ja active Pending
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009123102A1 (ja) | 2008-03-31 | 2009-10-08 | 旭化成ケミカルズ株式会社 | 崩壊性に優れる加工澱粉粉末及びその製法 |
| US8431618B2 (en) | 2008-03-31 | 2013-04-30 | Asahi Kasei Chemicals Corporation | Processed starch powder with excellent disintegration properties and manufacturing method thereof |
| JP5577241B2 (ja) * | 2008-03-31 | 2014-08-20 | 旭化成ケミカルズ株式会社 | 崩壊性に優れる加工澱粉粉末及びその製法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20040151767A1 (en) | 2004-08-05 |
| EP1443057A1 (en) | 2004-08-04 |
| EP1443057B1 (en) | 2006-12-13 |
| DE602004003599T2 (de) | 2007-09-27 |
| ATE348114T1 (de) | 2007-01-15 |
| US6846497B2 (en) | 2005-01-25 |
| ES2276175T3 (es) | 2007-06-16 |
| DE602004003599D1 (de) | 2007-01-25 |
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