JP2004035024A - Autoclave sterilizing blister package of improved peelability - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a convenient autoclave sterilizing blister package of considerably improved peelability which is sealed with sterilizing paper. <P>SOLUTION: The blister package B comprises a tray 1 and a sterilizing paper 2 affixed to a seal surface 17 of the tray 1, and a portion including at least a peeling surface 211 of a seal surface 21 of the sterilizing paper 2 is provided within ≥ 0.5 mm from an outer peripheral edge 22 of the sterilizing paper 2. <P>COPYRIGHT: (C)2004,JPO

Description

【００１１】
【表２】

【００１２】
【発明の効果】
以上述べたことから明らかなように、本発明を採用することにより、ピール性の著しく改良された、使い勝手の良い、滅菌紙でシールされたオートクレーブ滅菌用ブリスター包装体を提供することができる。
【図面の簡単な説明】
【図１】本発明の一実施例に係るブリスター包装体の平面図であり、プレフィルドシリンジ用トレーに滅菌紙を貼着した状態を示す。
【図２】図１の側面図である。
【図３】図１において滅菌紙を貼着する前のトレーを示す平面図である。
【図４】図１に示す包装体の使用状態の説明図である。
【図５】比較例における滅菌紙のシール面の基端縁および側縁の状態を示す図である。
【符号の説明】
１　トレー
１１　チップ収容部
１２　胴部先端側収容部
１３　胴部基端側収容部
１３１　小径部分
１４　フランジ収容部
１５　プランジャ収容部
１６　プランジャのフランジ収容部
１７　シール面
１８　開封突起
２　滅菌紙
２１　シール面
２１１　ピール対象面
２２　外周縁
２３　開封口
Ｂ　ブリスター包装体
Ｓ　プレフィルドシリンジ[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to improving the peelability of a blister package for autoclave sterilization sealed with sterilized paper, and is particularly suitable as a package for a prefilled syringe in which a plunger is attached to a gasket.
[0002]
[Prior art]
A blister package for autoclave sterilization usually includes a blister tray (hereinafter simply referred to as a tray) made of a transparent plastic such as polypropylene, polyethylene, or polystyrene, and a sealing member for sealing the tray. The seal width for sealing the members is usually required to be about 2 to 5 mm. Conventionally, in order to make the tray as compact as possible, the sealing surface of the tray has conventionally been the seal width including the outer peripheral edge of the tray. In such a blister package in which the sealing surface of the tray has a sealing width including the outer peripheral edge of the tray, if the sealing member is a plastic film, there is no problem because the film is difficult to tear, but the sealing member is made of sterilized paper. In such a case, it was torn in the middle of peeling, which was inconvenient and inconvenient.
On the other hand, in the case of products such as prefilled syringes that need to be stored in a tray, packaged, and sterilized, it is absolutely necessary that the sealing member that seals the tray be made of sterilized paper. Was waiting.
[0003]
Therefore, in order to avoid tearing of the sterilized paper when peeling, a method of facilitating peeling by weakening the seal strength or a method of providing a peel layer using an adhesive or the like have been studied, but the former is applied to the sealing surface. It has the drawback that there is a risk of pinhole formation, and the latter has a problem in that there are few adhesives that can withstand autoclave sterilization at 121 ° C. and, if any, it is expensive and expensive.
[0004]
[Problems to be solved by the invention]
The present invention has been made in view of the above circumstances, and it is an object of the present invention to provide an easy-to-use, easy-to-use, sterilized paper-sealed blister package for sterilizing autoclaves, which has significantly improved peelability.
[0005]
[Means for Solving the Problems]
The present inventors have conducted intensive studies to solve the above problems, and as a result, by shifting the sealing surface of the sterilized paper affixed to the tray inward from the outer peripheral edge of the sterilized paper by a predetermined distance, the peelability has been significantly improved. The present invention was completed. That is, the present invention comprises a blister tray and a sterilizing paper stuck on the sealing surface of the blister tray to seal the blister tray, and at least a portion of the sealing surface of the sterilizing paper including the surface to be peeled is the sterilizing paper. The present invention relates to a blister package for autoclave sterilization with improved peelability, which is provided at least 0.5 mm inside from the outer peripheral edge of the blister package. As a preferred embodiment of the present invention, a pair of opening protrusions are provided axially symmetrically at one end in the longitudinal direction of the sealing surface of the blister tray, and the three sealing surfaces of the sterilizing paper adjacent to the pair of opening protrusions are sterilized. And a package provided 0.5 mm or more inward from the outer peripheral edge of the paper. Here, the package of the present invention is suitable as a package for accommodating a prefilled syringe with a plunger.
[0006]
BEST MODE FOR CARRYING OUT THE INVENTION
Next, embodiments of the present invention will be described with reference to the drawings.
FIG. 1 is a plan view of a blister package for autoclave sterilization according to one embodiment of the present invention, showing a state where sterilized paper is stuck to a tray for prefilled syringe. FIG. 2 is a side view of FIG. 1, FIG. 3 is a plan view showing a tray before attaching sterilized paper in FIG. 1, and FIG. 4 is an explanatory view of a use state of the package shown in FIG. .
As shown in FIGS. 1 and 2, the blister package B of the present invention includes a tray 1 and a sterilized paper 2 attached to a sealing surface 17 of the tray 1. Is provided at least 0.5 mm inward from the outer peripheral edge 22 of the sterilized paper 2.
[0007]
The tray 1 is usually a dish-shaped container, and a sealing surface 17 is provided outside a portion for storing the product. In the case of a tray for a prefilled syringe, a portion for storing the prefilled syringe S has a tip accommodation portion 11 for accommodating the vicinity of the tip 31 of the barrel 3 as shown in FIGS. 3 is a torso-side accommodation section 12 for accommodating the tip side (except for the tip 31) of the torso, and a torso base-side accommodation section 13 for accommodating the torso of the barrel 3 (excluding the flange 32). A small-diameter portion 131 provided on the base end side of the body base end side housing portion 13, a flange housing portion 14 for housing the flange 32 of the barrel 3, a plunger housing portion 15 for housing the plunger 4 (excluding the flange 41); The base end is the flange accommodating portion 16 of the plunger that accommodates the flange 41 of the plunger 4. The trunk base-side accommodation section 13 has a larger diameter than the trunk end-side accommodation section 12, and has a size that allows a finger to be inserted when taking out the prefilled syringe S from the tray 1. The flange accommodating portion 14 is a portion for preventing the barrel 3 from moving in the tray 1, and therefore, the accommodating portions 131 and 15 adjacent thereto have smaller diameters than the flange.
[0008]
Sterilized paper 2 is adhered to the sealing surface 17 of the tray 1, and a pair of unsealing protrusions 18 are provided at one end of the plunger on the flange housing portion 16 side symmetrically with respect to the housing portion 16. . The number of the unsealing protrusion 18 may be one, but it is preferable to provide a pair of left and right in consideration of the dominant arm of the unsealed person. A portion corresponding to the opening projection 18 of the sterilizing paper 2 is an opening 23, and the sterilizing paper 2 can be peeled off by grasping the opening 23 with a finger.
The sterilized paper 2 is attached to the tray 1 such that at least a portion of the sealing surface 21 of the sterilized paper 2 including the surface 211 to be peeled is 0.5 mm or more inward from the outer peripheral edge 22 of the sterilized paper 2. . Note that the peel target surface 211 refers to the sealing surface 21 portion of the sterilized paper 2 to be peeled when the prefilled syringe S is taken out of the blister package B, and from the portion adjacent to the opening 23 at the base end of the sterilized paper 2. Begin. The distal end of the peel target surface 211 can be arbitrarily selected as long as it is located at the distal end side of the trunk base-side accommodation section 13, but the point is that when the sterilized paper 2 is peeled, a finger is inserted and the pre-filled syringe S is inserted. As long as the position can be taken out, a position corresponding to the trunk base side accommodation portion 13 may be used.
[0009]
[Test Example] Fifty blister packages each having a sealing surface as shown in Table 1 were prepared and subjected to a peeling test, and the results as shown in Table 2 were obtained. From Table 2, it can be seen that the peelability of the blister package of the present invention is significantly improved.
[0010]
[Table 1]

[0011]
[Table 2]

[0012]
【The invention's effect】
As is apparent from the above description, by adopting the present invention, it is possible to provide an easy-to-use, easy-to-use, sterilized paper-sealed blister package for sterilization of autoclave, which has significantly improved peelability.
[Brief description of the drawings]
FIG. 1 is a plan view of a blister package according to an embodiment of the present invention, showing a state in which sterilized paper is stuck to a prefilled syringe tray.
FIG. 2 is a side view of FIG.
FIG. 3 is a plan view showing the tray before attaching sterilized paper in FIG. 1;
FIG. 4 is an explanatory view of a use state of the package shown in FIG. 1;
FIG. 5 is a diagram showing a state of a base edge and a side edge of a sealing surface of sterilized paper in a comparative example.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 Tray 11 Chip accommodation part 12 Body tip side accommodation part 13 Body part base end accommodation part 131 Small diameter part 14 Flange accommodation part 15 Plunger accommodation part 16 Plunger flange accommodation part 17 Seal surface 18 Opening projection 2 Sterilization paper 21 Seal surface 211 Peel target surface 22 Outer edge 23 Opening opening B Blister package S Prefilled syringe

Claims (3)

A blister tray and a sterile paper stuck to the seal surface of the blister tray to seal the blister tray, wherein at least a portion of the seal surface of the sterile paper including a surface to be peeled is 0 mm from an outer peripheral edge of the sterile paper. A blister package for autoclave sterilization with improved peelability provided at least 5 mm inside. A pair of opening protrusions are provided axially symmetrically at one end in the longitudinal direction of the sealing surface of the blister tray, and the sealing surfaces on three sides of the sterilized paper adjacent to the pair of opening protrusions are 0.5 mm or more inward from the outer peripheral edge of the sterilized paper. The package according to claim 1, wherein the package is provided. The package according to claim 1 or 2, which is a package containing a prefilled syringe with a plunger.

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