JP2004016707A - Injector type drug capsule - Google Patents

Injector type drug capsule Download PDF

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Publication number
JP2004016707A
JP2004016707A JP2002179867A JP2002179867A JP2004016707A JP 2004016707 A JP2004016707 A JP 2004016707A JP 2002179867 A JP2002179867 A JP 2002179867A JP 2002179867 A JP2002179867 A JP 2002179867A JP 2004016707 A JP2004016707 A JP 2004016707A
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Japan
Prior art keywords
syringe
outer
drug
member
provided
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JP2002179867A
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JP4182692B2 (en
Inventor
Michio Kato
Hiroaki Murata
加藤 道雄
村田 浩昭
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Yuka Denshi Co Ltd
油化電子株式会社
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Priority to JP2002179867A priority Critical patent/JP4182692B2/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed

Abstract

<P>PROBLEM TO BE SOLVED: To provide an injector type drug capsule which is to separately store, mix, and push out two kinds of drugs and can easily and sufficiently mix two kinds of drugs. <P>SOLUTION: This injector type drug capsule is equipped with an outside syringe (1) which is equipped with an output port (11) and in which a first drug (A) is stored, an inside syringe (2) which is equipped with an outlet port (22) and in which a second drug (B) is stored, and a plunger (3) from which a boring rod (31) to open an outlet port (22) is protruded and which is inserted from the rear end of the inside syringe (2). A stirring member (4) to be rotated by the boring rod (31) is placed in the drug storage area of the outside syringe (1) to mix and stir the first drug (A) preliminarily stored in its storage area and the second drug (B) supplied from the inside syringe (2). <P>COPYRIGHT: (C)2004,JPO

Description

【0001】 [0001]
【発明の属する技術分野】 BACKGROUND OF THE INVENTION
本発明は、注射器型薬剤カプセルに関するものであり、詳しくは、2種の薬剤を別個に収容すると共にこれらを混合して押し出す注射器型薬剤カプセルに関するものである。 The present invention relates to a syringe type drug capsule, more particularly to a syringe type drug capsules extruding a mixture of these as well as separately housing the two agents.
【0002】 [0002]
【従来の技術】 BACKGROUND OF THE INVENTION
特開平8−131459号公報には、歯科治療において歯牙修復材料を投与するための「歯牙修復材用カプセル」が開示されている。 JP-A-8-131459, for administering the tooth restoration material "capsule for the tooth restorative material" is disclosed in dental treatment. 斯かる歯牙修復材用カプセルは、2種の薬剤を別個に収容すると共にこれらを混合して押し出す注射器型のカプセルであり、粉体成分が収納され且つ先端部にノズルが固定されたシリンダー状のカプセル本体と、内部に液体成分が収納され且つカプセル本体に後端側から嵌合する液体カップと、先端部に棒状突起を有し且つ液体カップに後端側から嵌合するプランジャーとから構成され、カプセル本体の先端には、薄膜状シールによって封止された混合物取出用の円形穴が設けられ、液体カップの先端には、薄膜状シールによって封止された液体成分の出口用の穴が設けられる。 Such capsule for the tooth restorative material is a capsule of the syringe-extruding a mixture of these as well as separately housing the two drugs, the powder component is accommodated and cylindrical nozzle is fixed to the distal end composed of a capsule body and a liquid cup liquid component therein is fitted from the rear end side is accommodated and capsule body, a plunger which is fitted from the rear side and a liquid cup has a rod-like projection at the tip portion is, at the distal end of the capsule body, a circular hole for mixture extraction sealed provided by a thin film-like seal, the tip of the liquid cup holes for exit of the liquid component sealed by a thin film-like seal It is provided.
【0003】 [0003]
上記の歯牙修復材用カプセルを使用する場合は、液体カップの奥端までプランジャーを押し込み、液体カップ先端の薄膜状シールを棒状突起によって破ることにより、カプセル本体に液体成分を注入し、カプセル本体内において歯牙修復材料としての混合物(混練物)を得る。 When using the above-mentioned capsule for the tooth restorative material is pushing the plunger to the back end of the liquid cup by breaking the thin film sealing liquid cup tip by rodlike protrusions, injection of the liquid component into the capsule body, the capsule body obtained mixture as the tooth restoration material (kneaded material) in the inner. なお、カプセル本体における粉体成分と液体成分の混合においては、専用のミキシング装置に歯牙修復材用カプセル全体を装填して機械的振動を与え、また、得られた混練物の取出においては、専用のアプライヤー(注入器具)を使用し、プランジャーと共に液体カップをカプセル本体の奥端に押し込むことにより、カプセル本体先端の薄膜状シールを棒状突起によって押し破り、ノズルから混練物を押し出す。 In the mixing of the powder and liquid components in the capsule body, giving the mechanical vibration loading the entire capsule for a tooth restoration material to a dedicated mixing unit, also in removal of the resulting kneaded product, dedicated of a using pliers (injection device), by pushing the liquid cup back end of the capsule body with plunger, breaks down the thin film sealing the capsule body distal end by the rod-like protrusions, extruding the kneaded product through a nozzle.
【0004】 [0004]
【発明が解決しようとする課題】 [Problems that the Invention is to Solve
ところで、上記の様なカプセルにおいて粉体成分と液体成分を混合する場合は、ミキシング装置などの専用機器が使用されるが、外部からの振動によって混合するため、十分に混合するには多くの合時間を必要とする。 In the case of mixing the powder and liquid components in the above such capsules is dedicated device such as a mixing device is used, for mixing by vibration from the outside, to mix well many case It needs time. 更に、ある種の高粘度の歯牙修復材などは、上記の構造のカプセルに収容した場合、外部振動によっては十分に混合できないと言う問題がある。 Furthermore, such tooth restoration material of certain high viscosity, when contained in a capsule of the above structure, there is a problem that can not be sufficiently mixed by external vibration. また、上記の様なカプセルにおいては、製造コストを低減する観点から、一層シンプルな構造が望まれる。 Further, in the above such capsules, from the viewpoint of reducing the manufacturing cost, a more simple structure would be desirable.
【0005】 [0005]
本発明は、上記の実情に鑑みてなされたものであり、その目的は、2種の薬剤を別個に収容すると共にこれらを混合して押し出す注射器型薬剤カプセルであって、シンプルな構造を備え、しかも、収容された2種の薬剤が高粘度の薬剤であっても、これらを簡単に且つ十分に混合することが出来る新規な構造の注射器型薬剤カプセルを提供することにある。 The present invention has been made in view of the above circumstances, the object is achieved by a syringe type drug capsules extruding a mixture of these as well as separately housing the two agents, provided with a simple structure, Moreover, even two agents contained is a drug of a high viscosity is to provide a syringe-drug capsules of novel structure capable of mixing them easily and sufficiently.
【0006】 [0006]
【課題を解決するための手段】 In order to solve the problems]
上記の課題を解決するため、本発明の注射器型薬剤カプセルは、2種の薬剤を別個に収容すると共にこれらを混合して押し出す注射器型薬剤カプセルであって、先端に取出口が設けられ且つ第1の薬剤が収容される外側シリンジと、先端に放出口が設けられ且つ第2の薬剤が収容されて前記外側シリンジの後端から挿入される内側シリンジと、当該内側シリンジの放出口を開口する穿孔ロッドが先端に突設され且つ前記内側シリンジの後端から挿入されるプランジャとを備え、前記外側シリンジの薬剤収容領域には、予め収容された第1の薬剤と前記内側シリンジから供給される第2の薬剤とを回転によって撹拌混合する攪拌部材が前記外側シリンジと同軸状に配置され、前記攪拌部材は、その中心部に設けられた軸穴にプランジャの前記穿 To solve the above problems, the syringe-type agents capsules of the present invention is a syringe-type agents capsules extruding a mixture of these as well as separately housing the two drugs, and provided takeout to the tip first opening an outer syringe first agent is housed, an inner syringe is inserted from the rear end of said outer syringe outlet is and the second agent is provided housed in the tip, the outlet of the inner syringe drilling rod and a plunger that is inserted from the rear end of and the inner syringe projecting from the tip, the medicine accommodating region of the outer syringe is supplied from the first agent in advance accommodated inside the syringe agitating member for agitating mixed by rotating the second agent disposed on the outer syringe coaxially, the agitating member, the puncture of the plunger shaft hole provided at the center thereof ロッドが挿通され且つ前記プランジャを回転操作されることにより、回転する様になされていることを特徴としている。 The rod is rotated the inserted through and the plunger is characterized by being made so as to rotate.
【0007】 [0007]
上記の注射器型薬剤カプセルにおいては、プランジャの押込み操作により、穿孔ロッドによって内側シリンジ先端の放出口を開口し、内側シリンジの第2の薬剤を外側シリンジに供給する。 In the above syringe type drug capsule by depressing the plunger, opens the outlet of the inner syringe tip by drilling rod, it supplies the second agent inside the syringe to the outer syringe. その際、プランジャの穿孔ロッドは、内側シリンジ先端の放出口を貫通して外側シリンジ先端側の薬剤収容領域に突出する。 At that time, drilling rod of the plunger protrudes into the medicine receiving region outside the syringe tip side through the outlet of the inner syringe tip. これにより、攪拌部材は、その中心部に設けられた軸穴にプランジャの穿孔ロッドが挿通されることにより当該穿孔ロッドによって係止される。 Thus, the agitating member is stopped by the perforation rod by piercing the rod of the plunger shaft hole provided in the center thereof is inserted. 従って、攪拌部材は、プランジャの回転操作により回転し、薬剤収容領域の第1の薬剤と第2の薬剤を撹拌混合する。 Therefore, the stirring member is rotated by rotational operation of the plunger, stirring and mixing a first agent and a second agent medicament containing region. そして、各薬剤を混合した後は、内側シリンジの押込み操作により、外側シリンジ先端の取出口通じ、混合された薬剤を押し出す。 Then, after mixing each drug, by depressing the inner syringe, through outlet of the outer syringe tip to push the mixed agent.
【0008】 [0008]
【発明の実施の形態】 DETAILED DESCRIPTION OF THE INVENTION
本発明の注射器型薬剤カプセルの実施形態を図面に基づいて説明する。 The embodiment of a syringe type drug capsules of the present invention will be described with reference to the drawings. 図1は、注射器型薬剤カプセルの一例の構成要素を示す部品展開斜視図である。 Figure 1 is a part exploded perspective view showing an example component of the syringe-drug capsules. 図2は、図1の注射器型薬剤カプセルの構成要素を中心線に沿って一部破断して示す側面図である。 Figure 2 is a side view, partly in cross section along the center line of the components of the syringe-like medicament capsule of Figure 1. 図3は、図1の注射器型薬剤カプセルの使用態様を中心線に沿って一部破断して示す側面図である。 Figure 3 is a side view, partly in cross section along the center line of the embodiment use of a syringe type drug capsule of Figure 1. 図4は、注射器型薬剤カプセルの他の例の構成要素を示す部品展開斜視図である。 Figure 4 is a part exploded perspective view showing components of another example of the syringe type drug capsules. 図5は、図4の注射器型薬剤カプセルの構成要素を中心線に沿って一部破断して示す側面図である。 Figure 5 is a side view, partly in cross section along the center line of the components of the syringe-like medicament capsule of FIG. 図6は、図4の注射器型薬剤カプセルの使用態様を中心線に沿って一部破断して示す側面図である。 Figure 6 is a side view, partly in cross section along the center line of the embodiment use of a syringe type drug capsule of FIG. 図7は、攪拌部材の幾つかの態様を示す斜視図である。 Figure 7 is a perspective view showing some aspects of the agitating member. なお、以下の実施形態の説明においては、注射器型薬剤カプセルを「カプセル」と略記する。 In the following description of the embodiments, a syringe type drug capsule abbreviated as "capsule".
【0009】 [0009]
本発明のカプセルは、2種の薬剤、すなわち、第1の薬剤(A)及び第2の薬剤(B)(図3又は図6参照)を別個に収容すると共にこれらを混合して押し出すいわゆる注射器の機能を備えた容器であり、図1、図2、図4及び図5に示す様に、主に、外側シリンジ(1)、内側シリンジ(2)、プランジャ(3)及び攪拌部材(4)とから構成される。 Capsules of the present invention, two drugs, i.e., so-called syringe extruding a mixture of these with the first agent (A) and the second drug (B) (see FIG. 3 or FIG. 6) is housed separately a vessel equipped with a function, FIG. 1, FIG. 2, as shown in FIGS. 4 and 5, primarily, the outer syringe (1), an inner syringe (2), a plunger (3) and the agitating member (4) composed of a.
【0010】 [0010]
本発明のカプセルに適用される第1の薬剤(A)及び第2の薬剤(B)としては、混合して使用されるべき薬剤であれば特に制限はなく、医薬品の他、歯牙修復材料(ペースト)、手術補助剤などの医薬品外の物質、接着剤、充填剤などの医療用途以外の物質が挙げられる。 The first agent (A) and a second agent that is applied to the capsule of the present invention (B), is not particularly limited as long as the agent to be used as a mixture, other medicines, the tooth restoration material ( paste), pharmaceuticals outside the substance such as surgical aids, adhesives include materials other than medical applications, such as fillers. 第1の薬剤(A)及び第2の薬剤(B)の少なくとも一方は液体またはゲルである。 At least one of the first agent (A) and the second agent (B) is a liquid or gel.
【0011】 [0011]
上記の外側シリンジ(1)は、第1の薬剤(A)を収容し且つ第1の薬剤(A)と第2の薬剤(B)を混合するための容器であり、通常は透明性の樹脂材料、典型的には耐薬品性および耐熱性に優れた環状ポリオレフィン、ポリプロピレン、ポリエチレン、ポリエチレンナフタレート、ポリカーボネート、ABS樹脂などの樹脂によって一体的に射出成形される。 Said outer syringe (1) is a container for mixing and first agent containing a first agent (A) (A) with a second agent (B), the normal transparency of the resin material, typically chemical resistance and heat resistance superior cyclic polyolefin, polypropylene, polyethylene, polyethylene naphthalate, polycarbonate, is injection molded integrally with a resin such as ABS resin. 外側シリンジ(1)の構成材料としては、上記の様な樹脂の他、積層構造になされた各種の樹脂、ガラス、セラミックス、金属などが挙げられる。 The constituent material of the outer syringe (1), in addition to the above such resin, the resin was made into a laminated structure variety, glass, ceramics, metals, and the like. 外側シリンジ(1)は略有底円筒状に形成され、その先端中心には取出口(11)が設けられる。 Outer syringe (1) is formed substantially in a bottomed cylindrical shape, outlet (11) is provided at its end center. 取出口(11)は、通常、外側シリンジ(1)の先端から突出するノズル状に形成される。 Outlet (11) is typically formed in a nozzle shape protruding from the distal end of the outer syringe (1). また、外側シリンジ(1)の後端には、後述する内側シリンジ(2)の操作の際に外側シリンジ(1)を支持するため、フランジ状に張出された掛止部(13)が設けられる。 Further, the rear end of the outer syringe (1), for supporting the outer syringe (1), Zhang out the hooking portion in a flange shape (13) is provided during the operation of the inner syringe (2) to be described later It is.
【0012】 [0012]
外側シリンジ(1)は、第1の薬剤(A)が収容されて取出口(11)を薄膜状のシール材やキャップ(図示省略)によって封止される。 Outer syringe (1) is sealed by the first agent (A) a thin film-like sealing member and the cap outlet (11) collected is accommodated (not shown). 外側シリンジ(1)の先端側、具体的には外側シリンジ(1)の前半部は薬剤収容領域とされ、当該薬剤収容領域においては、第1の薬剤(A)と第2の薬剤(B)を混合するため、例えばその半分の容積に相当する部分に第1の薬剤(A)が収容される。 The distal end side of the outer syringe (1), specifically the first half of the outer syringe (1) is a medicament containing region, in the medicine accommodating region, a first agent (A) with a second agent (B) for mixing the first agent (a) is accommodated for example in a portion corresponding to half of its volume. なお、外側シリンジ(1)の内容積は、歯牙材料に適用する場合で0.01〜10cm 程度である。 Incidentally, the internal volume of the outer syringe (1) is a 0.01~10Cm 3 about the case of applying to a tooth material.
【0013】 [0013]
また、本発明の好ましい態様においては、後述の攪拌部材(4)を外側シリンジ(1)内でより確実に進退させるため、図5に示す様に、薬剤収容領域を構成する外側シリンジ(1)の先端側の内周面には、攪拌部材(4)を案内する案内ネジ(15)が設けられる。 Further, in a preferred embodiment of the present invention, in order to more reliably reciprocating agitating member described later (4) outside the syringe (1) in, as shown in FIG. 5, the outer syringe constituting the medicine receiving area (1) the inner peripheral surface of the distal end side guide screw for guiding the stirring member (4) (15) is provided. 案内ネジ(15)は、これに係合した攪拌部材(4)の正逆回転により、当該攪拌部材を外側シリンジ(1)の軸線に沿って進退させる案内機能を有する。 Guide screw (15), the forward and reverse rotation of the engaged stirring member (4) to have a guiding function for advancing and retracting the agitating member along the axis of the outer syringe (1).
【0014】 [0014]
図1、図2、図4及び図5に示す内側シリンジ(2)は、第2の薬剤(B)を収容し且つ外側シリンジ(1)内で混合された第1の薬剤(A)及び第2の薬剤(B)を押し出す容器兼プランジャとして機能する部材であり、上記の外側シリンジ(1)と同様に、通常は各種の樹脂材料により一体的に射出成形される。 1, the inner syringe shown in FIGS. 2, 4 and 5 (2), the second agent (B) containing a and first agent which is mixed with the outer syringe (1) in (A) and the a member that functions as a container and a plunger for pushing the second agent (B), similarly to the outer syringe (1), typically is injection molded integrally with a variety of resin material. 勿論、ガラス等で構成されてもよい。 Of course, it may be composed of glass or the like. 内側シリンジ(2)は、外側シリンジ(1)の筒内に嵌合する外径の略有底円筒状に形成され、その先端中心には、放出口(22)が設けられる。 Inside the syringe (2) is formed in a substantially bottomed cylindrical outer diameter which fits into the cylinder of the outer syringe (1), in its end center, outlet (22) is provided. 内側シリンジ(2)の後端には、後述するプランジャ(3)の操作の際に内側シリンジ(2)を支持するため、フランジ状に張出された掛止部(23)が設けられる。 The rear end of the inner syringe (2), for supporting the inner syringe (2) during the operation of the plunger (3) to be described later, Zhang out the hooking portion in a flange shape (23) is provided.
【0015】 [0015]
内側シリンジ(2)の内部には、第2の薬剤(B)が収容され、放出口(22)は、例えば、内側シリンジ(2)と一体に成形された蓋状のシール部(21)によって封止される。 Inside the inner syringe (2), a second agent (B) is accommodated, outlet (22), for example, by an inner syringe (2) and a lid-like sealing portion formed integrally (21) It is sealed. シール部(21)は、後述の穿孔ロッド(31)によって開封される部位であり、内側シリンジ(2)の先端面において一部を残して形成された円環状の薄肉部(溝)によって構成される。 Seal portion (21) is a portion which is opened by piercing rod described later (31) is constituted by the thin portion of the annular formed leaving a part in the front end surface of the inner syringe (2) (a groove) that. なお、内側シリンジ(2)の内容積は、歯牙材料に適用する場合で0.01〜10cm 程度である。 Incidentally, the internal volume of the inner syringe (2) is a 0.01~10Cm 3 about the case of applying to a tooth material.
【0016】 [0016]
また、上記の様に、外側シリンジ(1)の内周面に案内ネジ(15)が設けられる場合、図4及び図5に示す様に、内側シリンジ(2)の掛止部(23)を除く部位の外形は2段の有底円筒状に形成される。 Further, as described above, when the guide screw (15) is provided on the inner peripheral surface of the outer syringe (1), as shown in FIGS. 4 and 5, engaging portion of the inner syringe (2) (23) contour of the portion except for being formed into a bottomed cylindrical second stage. すなわち、外側シリンジ(1)の奥端まで内側シリンジ(2)を挿入した際に内側シリンジ(2)が外側シリンジ(1)の内周面に密接に嵌合する様に(図6(d)参照)、内側シリンジ(2)の外周部は、案内ネジ(15)に対応する前半部の外径を後半部の外径よりも小さく設定される。 That is, as the inner syringe when inserting the inner syringe (2) to the back end of the outer syringe (1) (2) is closely fitted to the inner peripheral surface of the outer syringe (1) (FIG. 6 (d) see), the outer peripheral portion of the inner syringe (2) is set smaller than the outer diameter of the rear half portion of the outer diameter of the front half section corresponding to the guide screw (15).
【0017】 [0017]
図1、図2、図4及び図5に示すプランジャ(3)は、内側シリンジ(2)に収容された第1の薬剤(A)を外側シリンジ(1)へ押し出すための押圧部材であり、上記の外側シリンジ(1)と同様に、通常は各種の樹脂材料により一体的に射出成形される。 1, FIG. 2, the plunger shown in FIG. 4 and FIG. 5 (3) is a pressing member for pressing a first agent which is housed inside the syringe (2) (A) to the outer syringe (1), Like the outer syringe (1), typically is injection molded integrally with a variety of resin material. 外側シリンジ(1)と同様にガラス等で構成されてもよい。 May be composed of glass or the like similarly to the outer syringe (1). 図3又は図6に示す様に、プランジャ(3)は、内側シリンジ(2)の筒内に嵌合する略円柱状に形成され、図1、図2、図4及び図5に示す様に、その先端中心には、内側シリンジ(2)の放出口(22)を開口する穿孔ロッド(31)が突設される。 As shown in FIG. 3 or FIG. 6, the plunger (3) is formed in a substantially cylindrical shape which fits into the cylinder of the inner syringe (2), 1, 2, as shown in FIGS. 4 and 5 , to its end center opening punching rod (31) is projecting an outlet of the inner syringe (2) (22). また、プランジャ(3)の後端には、後述する様に、プランジャ(3)の押し込み操作および回転操作を容易にするため、例えば扁平箱形に張出された把持部(33)が設けられる。 Further, the rear end of the plunger (3), as described below, to facilitate the pushing operation and rotational operation of the plunger (3), for example, Zhang out the grip portion into a flat box shape (33) is provided . そして、上記のプランジャ(3)は、内側シリンジ(2)の後端から挿入される。 The above plunger (3) is inserted from the rear end of the inner syringe (2).
【0018】 [0018]
プランジャ(3)の穿孔ロッド(31)は、放出口(22)のシール部(21)を突き破る機能と、後述の攪拌部材(4)を係止して操作する機能を有する。 Plunger (3) drilling rod (31) of has a function pierce a seal of the outlet (22) (21), a function of operating engages the stirring member (4) below. 穿孔ロッド(31)の長手方向に直交する断面形状は、後述の攪拌部材(4)の軸穴(41)に嵌合する非円形の形状とされる。 Sectional shape perpendicular to the longitudinal direction of the drilling rod (31) is a non-circular shape which fits into the shaft hole (41) of the agitating member (4) described later. 例えば、穿孔ロッド(31)の上記の断面形状は四角形に形成される。 For example, the cross-sectional shape of the perforation rod (31) is formed in a rectangular shape.
【0019】 [0019]
更に、穿孔ロッド(31)の先端部の形状は、当該穿孔ロッドを外側シリンジ(1)内部に進入させた場合に上記の軸穴(41)に円滑に挿入し得る様に、先端に向かうに従い断面積が漸次小さくなる形状とされる(図1及び図4参照)。 Furthermore, the shape of the tip of the piercing rod (31), as may be smoothly inserted into the shaft hole (41) when caused to enter the perforation rod outer syringe (1) inside, toward the distal end the cross-sectional area are gradually becomes smaller shape (see FIGS. 1 and 4). 更に、穿孔ロッド(31)の長さは、プランジャ(3)を内側シリンジ(2)に押し込み、更に内側シリンジ(2)を外側シリンジ(1)に押し込んだ場合、外側シリンジ(1)の取出口(11)の内部または先端部に達する程度の長さに設定される(図3(d)及び図6(d)参照)。 Further, the length of the piercing rod (31), pushing the plunger (3) inside the syringe (2), further if pushed inside the syringe (2) outside the syringe (1), collected outside the syringe (1) outlet enough to reach the inside or distal end (11) is set to the length (see FIG. 3 (d) and FIG. 6 (d)).
【0020】 [0020]
本発明のカプセルにおいては、収容した第1の薬剤(A)及び第2の薬剤(B)を強制的に撹拌混合するため、図1、図2、図4及び図5に示す様に、外側シリンジ(1)の先端側の薬剤収容領域、すなわち、外側シリンジ(1)の前半部には、第1の薬剤(A)と第2の薬剤(B)を回転によって撹拌混合する攪拌部材(4)が外側シリンジ(1)と同軸状に配置される。 In the capsules of the present invention, the first agent (A) and the second agent (B) forcibly for agitating mixing accommodating, as shown in FIG. 1, 2, 4 and 5, the outer the distal end side of the medicine accommodating region of the syringe (1), that is, the first half of the outer syringe (1), stirring member (4 stirring mixed by rotating the first agent (a) with a second agent (B) ) is disposed outside the syringe (1) and coaxially. 斯かる攪拌部材(4)は、図7に示す様に、その中心部に設けられた軸穴(41)にプランジャ(3)の穿孔ロッド(31)が挿通され且つプランジャ(3)が回転操作されることにより、回転する様になされている。 Such stirring member (4) is, as shown in FIG. 7, the perforation rod of the plunger to the shaft hole (41) provided in the central portion (3) (31) is inserted and the plunger (3) is rotating operation by being, it has been made so as to rotate. これにより、薬剤の粘度に拘わらず、2種の薬剤を確実に混合することが出来る。 Thus, regardless of the viscosity of the drug can be reliably mixed with two agents.
【0021】 [0021]
上記の攪拌部材(4)の形態としては、回転によって撹拌機能を発揮し得る限り、例えば図7に示す様に、各種の形態が挙げられる。 The form of the above-mentioned stirring member (4), as long as capable of exhibiting stirred functions by rotating, for example, as shown in FIG. 7, various forms can be mentioned. 具体的には、最も簡単な構造の攪拌部材(4)としては、図7(g)に示す様な部材が挙げられる。 Specifically, the stirring member of the simplest structure (4) include members such as shown in FIG. 7 (g). 図 (g)に示す攪拌部材(4)は、軸穴(41)が設けられたハブ(40)から複数のバー(42)を外側シリンジ(1)の半径方向に張出して成る。 FIG stirring member (4) shown in (g) consists Te projecting shaft hole (41) a plurality of bars from the hub (40) which is provided (42) in the radial direction of the outer syringe (1). ハブ(40)は、攪拌部材(4)の回転中心となる部位であり、上記の穿孔ロッド(31)を挿通するための軸穴(41)を備えている。 Hub (40) is a portion serving as a rotation center of the agitating member (4) is provided with a shaft hole (41) for inserting the perforation rod (31). 上記の攪拌部材(4)は、その回転により、バー(42)によって外側シリンジ(1)内の薬剤を撹拌する。 Additional stirring member (4), by their rotation, stirring the drug outside the syringe (1) in the bar (42).
【0022】 [0022]
ハブ(40)の軸穴(41)の形状(軸芯に垂直な断面形状)は、穿孔ロッド(31)を係合させた際に当該穿孔ロッドが空回することのない様に、穿孔ロッド(31)の断面と同様の非円形の形状に形成される。 Hub (the cross-sectional shape perpendicular to the axis) the shape of the shaft hole (41) in (40), as the drilling rod not to empty times upon engaging the perforation rod (31), drilling rods (31) is formed in the same noncircular shape as the cross-section of the. 軸穴(41)の形状としては、図示する様な四角形の他、五角形、六角形、半円形などの適宜の形状を採用し得る。 The shape of the shaft hole (41), other such as shown square, pentagonal, hexagonal, may be employed an appropriate shape, such as semicircular.
【0023】 [0023]
また、攪拌部材(4)としては、図7(a)及び図7(b)に示す様なものでもよい。 As the stirring member (4), FIGS. 7 (a) and it may be such as shown in FIG. 7 (b). 図7(a)及び図7(b)に示す攪拌部材(4)は、軸穴(41)が設けられたハブ(40)から複数の羽根(43)を外側シリンジ(1)の半径方向に張出して成るプロペラ型の部材である。 FIGS. 7 (a) and stirring member (4) shown in FIG. 7 (b), a plurality of vanes (43) from the hub (40) of the shaft hole (41) is provided in the radially outer syringe (1) it is a member of the propeller formed by overhanging. 羽根(43)の数は、通常、2〜5枚程度である。 The number of wings (43), usually about 2 to 5 sheets. 軸穴(41)の形状は上記の場合と同様である。 The shape of the shaft hole (41) is the same as in the above. 斯かる攪拌部材(4)は、羽根(43)が一方向に捻られているため、回転により推力を発生し、回転方向によって外側シリンジ(1)内を進退する様になされている。 Such stirring member (4), since the blades (43) are twisted in one direction, the thrust generated by the rotation has been made so as to advance and retract the outer syringe (1) in the direction of rotation. 従って、上記の攪拌部材(4)は、これを正逆回転させることにより、一層すぐれた撹拌混合効果を発揮する。 Therefore, the above agitating member (4), which by normal and reverse rotation, exerts a stirred mixture effects more excellent.
【0024】 [0024]
更に、図5に示す様に外側シリンジ(1)の内周面に案内ネジ(15)が設けられている場合には、上記のプロペラ型の攪拌部材(4)は、図7(c)及び図7(d)に示す様な形態に構成される。 Further, when the guide screw (15) on the inner peripheral surface of the outer syringe (1) as shown in FIG. 5 are provided, stirring member (4) of propeller of the above, and FIG. 7 (c) and configured to a configuration as shown in FIG. 7 (d). すなわち、図7(c)及び図7(d)に示す攪拌部材(4)においては、図7(a)及び図7(b)に示す部材の基本構造に加え、案内ネジ(15)に係合する突起(45)が各羽根(43)の先端に付設される。 That is, in the stirring member (4) shown in FIG. 7 (c) and FIG. 7 (d), the addition to the basic structure of the member shown in FIG. 7 (a) and 7 (b), the guide engages the screw (15) if projections (45) is attached to the tip of each blade (43). そして、斯かる撹拌部材(4)は、その回転により案内ネジ(15)に沿って外側シリンジ(1)の軸方向へ移動可能(進退可能)に構成される(図6参照)。 Then, such stirring member (4) is configured to be movable (retractable) thereof in the axial direction of the outer syringe guided along the screw (15) by rotation (1) (see FIG. 6). 上記の様に、外側シリンジ(1)の案内ネジ(15)に攪拌部材(4)の突起(45)を係合させた場合には、攪拌部材(4)を回転させることにより、強制的に攪拌部材(4)を進退させることが出来、粘度の高い薬剤であっても、確実に撹拌混合できる。 As described above, when the projection of the agitating member (4) to (45) is engaged in the guide screw (15) of the outer syringe (1), by rotating the stirring member (4), forcibly It can advance and retract the stirring member (4), even at high viscosity agents, can be reliably stirred mixture.
【0025】 [0025]
また、攪拌部材(4)としては、図7(e)及び図7(f)に示す様な部材が挙げられる。 As the stirring member (4) include members such as shown in FIG. 7 (e) and FIG. 7 (f). 図7(e)及び図7(f)に示す攪拌部材(4)は、中心部に軸穴(41)が設けられた螺旋円盤型の部材である。 Figure 7 (e) and stirring member (4) shown in FIG. 7 (f) is a member of the spiral disk type shaft hole (41) is provided at the center portion. 斯かる攪拌部材(4)の円盤部(44)は、各分図に示す様に、一重でも二重でもよい。 Disk portion of such agitating member (4) (44), as shown in the partial view, may be a double any single. 円盤部(44)中心のの軸穴(41)の形状は上記の場合と同様である。 Shape of the disk portion (44) the center of the shaft hole (41) is the same as in the above.
【0026】 [0026]
更に、図5に示す様に外側シリンジ(1)の内周面に案内ネジ(15)が設けられている場合には、上記の螺旋円盤型の攪拌部材(4)は、円盤部(44)の外周縁が案内ネジ(15)に係合し、当該撹拌部材の回転により案内ネジ(15)に沿って外側シリンジ(1)の軸方向へ移動可能に構成される。 Further, when the guide screw (15) is provided on the inner peripheral surface of the outer syringe (1) as shown in FIG. 5, the stirring member (4) of the spiral disk type, disk portion (44) of the outer peripheral edge engages guide the screw (15), movable in along the guide screw (15) by rotation of the stirring member in the axial direction of the outer syringe (1). 上記の様に、外側シリンジ(1)の案内ネジ(15)に攪拌部材(4)の円盤部(44)の外周縁を係合させた場合には、上記の場合と同様に、攪拌部材(4)を回転させることにより、強制的に攪拌部材(4)を進退させることが出来、粘度の高い薬剤の撹拌混合に好適である。 As described above, when engaging the outer peripheral edge of the disk portion (44) of the agitating member guiding the screw (15) of the outer syringe (1) (4), as in the case of the stirring member ( by rotating the 4), forcing it is possible to advance and retreat the stirring member (4) is suitable for stirring and mixing the high viscosity agents.
【0027】 [0027]
また、図7に示す各態様の上記の攪拌部材(4)は、通常、耐薬品性および耐熱性に優れたポリオレフィン、ポリプロピレン、ポリエチレン、ポリエチレンナフタレート等の樹脂を射出成形して作製されるが、特に、図7(a)〜図7(f)に示す攪拌部材(4)は、柔弾性を有する材料によって構成されるのが好ましい。 Further, the above-mentioned stirring member (4) of the embodiment shown in Figure 7, typically, chemical resistance and excellent heat resistance polyolefins, polypropylene, polyethylene, a resin such as polyethylene naphthalate is produced by injection molding in particular, stirring member (4) shown in FIG. 7 (a) ~ FIG 7 (f) is preferably made of a material having soft elastic. 勿論、金属等の材料で構成されてもよい。 Of course, it may be formed of a material such as metal. 攪拌部材(4)は柔弾性材料によって構成されている場合には、外側シリンジ(1)の奥端まで内側シリンジ(2)を押し込んだ際、扁平状態に攪拌部材(4)を変形させることが出来るため、混合した薬剤をより多く効率的に取り出すことが出来る(図3(d)及び図6(d)参照)。 Stirring member (4) when it is constituted by a soft elastic material, when pushed inside the syringe (2) to the back end of the outer syringe (1), may deform the stirring member (4) in the flat state it can therefore, can be taken out by mixing the drug more efficiently (refer to FIG. 3 (d) and FIG. 6 (d)).
【0028】 [0028]
次に、本発明のカプセルの使用方法および機能について図3及び図6を参照して説明する。 It will now be described with reference to FIGS. 3 and 6 for the use and functions of the capsule of the present invention. 本発明のカプセルを使用する場合には、先ず、図3(a)及び図6(a)に示す状態からプランジャ(3)の押込み操作により、内側シリンジ(2)の後端側から先端へ向けてプランジャ(3)を押し込み、図3(b)及び図6(b)に示す様に、穿孔ロッド(31)によって内側シリンジ(2)先端の放出口(22)を開口し、そして、内側シリンジ(2)の第2の薬剤(B)を外側シリンジ(1)の薬剤収容領域に供給する。 When using capsules of the present invention, first, by depressing the plunger (3) from the state shown in FIG. 3 (a) and 6 (a), directed from the rear end side of the inner syringe (2) to the tip Te pushing the plunger (3), as shown in FIG. 3 (b) and 6 (b), opening in the inner syringe (2) the tip of the outlet (22) by drilling rod (31), and, inside the syringe (2) a second agent (B) supplied to the medicine receiving region outside the syringe (1).
【0029】 [0029]
上記の様に、内側シリンジ(2)の放出口(22)を開口させた場合、プランジャ(3)の穿孔ロッド(31)は、内側シリンジ(2)先端の放出口(22)を貫通して外側シリンジ(1)先端側の薬剤収容領域に突出する。 As described above, when outlet inside the syringe (2) (22) is opened, the perforation rod of the plunger (3) (31) penetrates inside the syringe (2) the tip of the outlet (22) projecting the medicine receiving region outside the syringe (1) the distal end side. 一方、上記の薬剤収容領域には攪拌部材(4)が配置されており、斯かる攪拌部材(4)はその中心部に軸穴(41)が設けられているため、上記のプランジャ(3)の押し込み操作により、穿孔ロッド(31)は、攪拌部材(4)の軸穴(41)を貫通して攪拌部材(4)を係止する。 On the other hand, in the above medicine accommodating region is disposed agitating member (4) is such a stirring member (4) Since the shaft hole (41) is provided at the center thereof, said plunger (3) by the pressing operation, drilling rod (31) to lock the stirring member (4) through the shaft hole of the agitating member (4) (41).
【0030】 [0030]
次いで、図3(c)及び図6(c)に示す様に、プランジャ(3)を回転操作すると、穿孔ロッド(31)に係止された攪拌部材(4)が回転し、攪拌部材(4)は、その回転により、外側シリンジ(1)の薬剤収容領域に予め収容された第1の薬剤(A)と内側シリンジ(2)から供給された第2の薬剤(B)を撹拌混合する。 Then, as shown in FIG. 3 (c) and FIG. 6 (c), the when rotating the plunger (3), stirring member (4) which is engaged in drilling rod (31) is rotated, the stirring member (4 ), by their rotation, stirring and mixing a second agent which is supplied the first drug (a) which is previously accommodated in the medicine receiving region outside the syringe (1) from the inside the syringe (2) (B). なお、攪拌部材(4)を回転させる場合には、内側シリンジ(2)を回転操作することにより、内側シリンジ(2)と共にプランジャ(3)を回転させてもよい。 Incidentally, in the case of rotating the stirring member (4), by rotating the inner syringe (2), a plunger (3) may be rotated with the inner syringe (2).
【0031】 [0031]
また、上記の撹拌混合の際、特に、図6に示す様に、外側シリンジ(1)の内周面に案内ネジ(15)が設けられ且つ当該案内ネジに攪拌部材(4)が係合している場合には、攪拌部材(4)を回転させることにより、外側シリンジ(1)内で強制的に攪拌部材(4)を進退させることが出来るため、粘度の高い薬剤でも、確実に撹拌混合することが出来る。 Further, when the above-described stirring and mixing, in particular, as shown in FIG. 6, stirring and the guide screw guide screw (15) is provided on the inner peripheral surface of the outer syringe (1) member (4) is engaged If it is, by rotating the stirring member (4), since it is possible to forcibly retreat the stirring member (4) outside the syringe (1) in, even at high viscosity agents, reliably stirred mixture to it can be.
【0032】 [0032]
そして、第1の薬剤(A)と第2の薬剤(B)を混合した後は、図3(d)及び図6(d)に示す様に、プランジャ(3)と共に内側シリンジ(2)を外側シリンジ(1)の奥端へ押し込むことにより、外側シリンジ(1)先端の取出口(11)から混合された薬剤を押し出すことが出来る。 Then, after mixing the first agent (A) with a second agent (B), as shown in FIG. 3 (d) and FIG. 6 (d), the inner syringe with plunger (3) (2) by pushing the rear end of the outer syringe (1), it is possible to push the drug mixed from outside the syringe (1) the tip of the outlet (11).
【0033】 [0033]
なお、本発明のカプセルは、勿論、指先で操作することも出来るが、通常は専用のアプライヤー(薬剤注入器具)を使用して操作される。 Incidentally, the capsule of the present invention is, of course, also possible to operate with a fingertip and is usually operated using a dedicated applier (drug infusion device). 斯かるアプライヤーは、概略、先端部にカプセル全体を収納保持するガン状の本体と、当該本体内に配置されて先端側へ伸びるプランジャ送出し用の押し込み棒と、ラック・ピニオン機構を介して押し込み棒に連接する押し込み棒回転操作用の操作バーとから成り、本体に付設された引金状のレバーの把持操作により、押し込み棒を段階的に押出操作してプランジャ(3)、内側シリンジ(2)をそれぞれ押し込み、操作バーを押送操作して押し込み棒を正逆回転させる器具である。 Such applier is a schematic, through a gun-like body for accommodating and holding the whole capsule tip, the push-rod for and plunger sends extending distally disposed within the body, a rack and pinion mechanism pushing consists of a manipulation bar for push-rod rotating operation for connecting the rod, the gripping operation of the annexed been trigger-like lever main body, a plunger (3) by stepwise extrusion operation the push rod, the inner syringe ( push 2), respectively, it is a rod pushing and pusher operating the operation bar an instrument to rotate forward and backward.
【0034】 [0034]
上記の様に、本発明のカプセルは、主に、外側シリンジ(1)、内側シリンジ(2)、プランジャ(3)及び攪拌部材(4)の4つの部材が同軸状に配置されたシンプルな構造を備えている。 As described above, the capsule of the present invention is mainly outside the syringe (1), an inner syringe (2), a simple structure in which four members are arranged coaxially of the plunger (3) and the agitating member (4) It is equipped with a. そして、本発明のカプセルにおいては、外側シリンジ(1)の薬剤収容領域に攪拌部材(4)が予め配置され、内側シリンジ(2)から外側シリンジ(1)の薬剤収容領域に第1の薬剤(A)を供給して第2の薬剤(B)と混合する際にプランジャ(3)の穿孔ロッド(31)で攪拌部材(4)を係止し、そして、プランジャ(3)の回転操作により攪拌部材(4)を強制的に回転させる様になされているため、外側シリンジ(1)の薬剤収容領域において第1の薬剤(A)と第2の薬剤(B)を簡単に且つ十分に混合することが出来る。 Then, in the capsules of the present invention, the agitating member to the medicine receiving region (4) is arranged in advance of the outer syringe (1), the first agent from the inner syringe (2) the medicament containing the region of the outer syringe (1) ( locking the stirring member (4) in drilling rod of the plunger (3) (31) when mixing with a second agent (B) by supplying a), and stirring by the rotation operation of the plunger (3) because it is made so as to forcibly rotate the member (4), simple mixing and sufficiently the first agent (a) with a second agent (B) in the medicine accommodating area outside the syringe (1) it can be.
【0035】 [0035]
更に、本発明のカプセルにおいて、外側シリンジ(1)の内周面に案内ネジ(15)が設けられ且つ当該案内ネジに攪拌部材(4)が係合している場合には、外側シリンジ(1)内で攪拌部材(4)を回転させつつ強制的に進退させることが出来るため、粘度の高い薬剤でも、確実に撹拌混合することが出来る。 Further, in the capsule of the present invention, when the stirring and the guide screw guide screw (15) is provided on the inner peripheral surface of the outer syringe (1) member (4) is engaged, the outer syringe (1 ) in order to agitating member (4) it can be forced to retreat while rotating at, even at high viscosity agents, can be reliably stirred mixture. なお、本発明のカプセルは、歯牙材料だけでなく、粘性の高い各種の薬剤に好適であり、また、外側シリンジ(1)及び内側シリンジ(2)の形状や大きさは、収容される薬剤や用途に応じて適宜に設計できる。 Incidentally, the capsule of the present invention, not only the tooth material is suitable for a highly viscous various drugs, also the shape and size of the outer syringe (1) and the inner syringe (2), the drug to be contained Ya It can be designed as appropriate according to the use.
【0036】 [0036]
【発明の効果】 【Effect of the invention】
以上説明した様に、本発明の注射器型薬剤カプセルによれば、外側シリンジの薬剤収容領域に攪拌部材が予め配置され、内側シリンジから外側シリンジの薬剤収容領域に第1の薬剤を供給して第2の薬剤と混合する際にプランジャの穿孔ロッドで攪拌部材を係止し、そして、プランジャの回転操作により攪拌部材を強制的に回転させる様になされているため、外側シリンジの薬剤収容領域において第1の薬剤と第2の薬剤を簡単に且つ十分に混合することが出来る。 As described above, according to the syringe-drug capsules of the present invention, the agitating member is disposed in advance in the medicine accommodating region outside the syringe, the supplying a first agent from the inner syringe medicine accommodating region outside the syringe locking the stirring member with the plunger drilling rod upon mixing with second agent, and, because they are made so as to forcibly rotate the stirring member by the rotation operation of the plunger, the in drug accommodating region of the outer syringe 1 agent and the second agent easily and sufficiently, it is possible to mix.
【図面の簡単な説明】 BRIEF DESCRIPTION OF THE DRAWINGS
【図1】注射器型薬剤カプセルの一例の構成要素を示す部品展開斜視図である。 1 is a part exploded perspective view illustrating components of an example of a syringe type drug capsules.
【図2】図1の注射器型薬剤カプセルの構成要素を中心線に沿って一部破断して示す側面図である。 2 is a side view, partly in cross section along the center line of the components of the syringe-like medicament capsule of Figure 1.
【図3】図1の注射器型薬剤カプセルの使用態様を中心線に沿って一部破断して示す側面図である。 3 is a side view, partly in cross section along the center line of the usage mode of the syringe type drug capsule of Figure 1.
【図4】注射器型薬剤カプセルの他の例の構成要素を示す部品展開斜視図である。 4 is a part exploded perspective view showing components of another example of the syringe type drug capsules.
【図5】図4の注射器型薬剤カプセルの構成要素を中心線に沿って一部破断して示す側面図である。 5 is a side view, partly in cross section along the center line of the components of the syringe-like medicament capsule of FIG.
【図6】図4の注射器型薬剤カプセルの使用態様を中心線に沿って一部破断して示す側面図である。 6 is a side view, partly in cross section along the center line of the usage mode of the syringe type drug capsule of FIG.
【図7】攪拌部材の幾つかの態様を示す斜視図である。 7 is a perspective view showing some aspects of the agitating member.
【符号の説明】 DESCRIPTION OF SYMBOLS
1 :外側シリンジ11:取出口13:掛止部15:案内ネジ2 :内側シリンジ21:シール材22:放出口23:掛止部3 :プランジャ31:穿孔ロッド33:把持部4 :攪拌部材40:ハブ41:軸穴42:バー43:羽根44:円盤45:突起A :薬剤(第1の薬剤) 1: outer syringe 11: outlet 13: hook member 15: guide screws 2: inner syringe 21: sealing material 22: discharge port 23: retaining portion 3: Plunger 31: piercing rod 33: gripping portion 4: stirring member 40 : hub 41: shaft hole 42: bar 43: blade 44: disk 45: protrusion a: drug (first agent)
B :薬剤(第2の薬剤) B: drug (second drug)
C :混合薬剤 C: mixing drugs

Claims (6)

  1. 2種の薬剤(A,B)を別個に収容すると共にこれらを混合して押し出す注射器型薬剤カプセルであって、先端に取出口(11)が設けられ且つ第1の薬剤(A)が収容される外側シリンジ(1)と、先端に放出口(22)が設けられ且つ第2の薬剤(B)が収容されて外側シリンジ(1)の後端から挿入される内側シリンジ(2)と、内側シリンジ(2)の放出口(22)を開口する穿孔ロッド(31)が先端に突設され且つ内側シリンジ(2)の後端から挿入されるプランジャ(3)とを備え、外側シリンジ(1)の薬剤収容領域には、予め収容された第1の薬剤(A)と内側シリンジ(2)から供給される第2の薬剤(B)とを回転によって撹拌混合する攪拌部材(4)が外側シリンジ(1)と同軸状に配置され、攪拌部材(4)は、 Two agents (A, B) a syringe-type agents capsules extruding a mixture of them with a separately housed, and the first agent is provided an outlet (11) collected by the tip (A) is contained that the outer syringe (1), an inner syringe (2) inserted from the rear end of the outer syringe (1) outlet (22) is provided and a second agent (B) is accommodated in the distal end, the inner syringe (2) of the outlet comprises drilling rod opening (22) (31) and a plunger (3) which is inserted from the rear end of and inside the syringe is protruded from the distal end (2), the outer syringe (1) the drug receiving area, a first agent (a) with a second agent (B) and the agitating member (4) for mixing and stirring by the rotation supplied from the inner syringe (2) is an outer syringe which is previously accommodated (1) and are arranged coaxially, stirring member (4) の中心部に設けられた軸穴(41)にプランジャ(3)の穿孔ロッド(31)が挿通され且つプランジャ(3)を回転操作されることにより、回転する様になされていることを特徴とする注射器型薬剤カプセル。 By drilling rod of the plunger (3) (31) is rotated the inserted through and the plunger (3) in the shaft hole (41) provided at the center of, and characterized by being made so as to rotate syringe-drug capsules.
  2. 攪拌部材(4)は、軸穴(41)が設けられたハブ(40)から複数のバー(42)を外側シリンジ(1)の半径方向に張出して成る部材である請求項1に記載の注射器型薬剤カプセル。 Stirring member (4) is a syringe according to claim 1, wherein the member made Te projecting radially of the shaft hole hub (41) is provided (40) from a plurality of bars (42) outside the syringe (1) type drug capsule.
  3. 攪拌部材(4)は、軸穴(41)が設けられたハブ(40)から複数の羽根(43)を外側シリンジ(1)の半径方向に張出して成るプロペラ型の部材である請求項1に記載の注射器型薬剤カプセル。 Stirring member (4) is in claim 1 in the radial direction is a member of the propeller comprising Te projecting axial bore (41) a plurality of blades from the hub (40) which is provided (43) an outer syringe (1) syringe-drug capsule according.
  4. 薬剤収容領域を構成する外側シリンジ(1)の先端側の内周面には案内ネジ(15)が設けられ、撹拌部材(4)の各羽根(43)の先端には案内ネジ(15)に係合する突起(45)が付設され、撹拌部材(4)は、その回転により案内ネジ(15)に沿って外側シリンジ(1)の軸方向へ移動可能に構成されている請求項3に記載の注射器型薬剤カプセル。 Guide screw on the inner circumferential surface of the distal end of the outer syringe (1) (15) is provided which constitutes the medicine accommodating region, the tip of each blade (43) of the stirring member (4) to the guide screw (15) It is attached protrusion for engaging (45), agitator (4), according to claim 3 which is movable in the axial direction of the outer syringe (1) along the guide screw (15) by its rotation syringe-drug capsules.
  5. 攪拌部材(4)は、中心部に軸穴(41)が設けられた螺旋円盤型の部材である請求項1に記載の注射器型薬剤カプセル。 Stirring member (4) is a syringe type drug capsule according to claim 1 in the center shaft hole (41) is a member of the spiral disk type provided.
  6. 薬剤収容領域を構成する外側シリンジ(1)の先端側の内周面には案内ネジ(15)が設けられ、撹拌部材(15)の円盤(44)の外周縁は案内ネジ(15)に係合し、撹拌部材(4)は、その回転により案内ネジ(15)に沿って外側シリンジ(1)の軸方向へ移動可能に構成されている請求項5に記載の注射器型薬剤カプセル。 The inner peripheral surface of the distal end of the outer syringe (1) which constitutes the medicine accommodating region is provided a guide screw (15), the outer peripheral edge of the disk (44) of the stirring member (15) is engaged with the guide screw (15) combined, the stirring member (4) is a syringe type drug capsule according to claim 5 which is movable in the axial direction of the outer syringe (1) along the guide screw (15) by its rotation.
JP2002179867A 2002-06-20 2002-06-20 Syringe-drug capsule Expired - Fee Related JP4182692B2 (en)

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JP2009542427A (en) * 2006-07-06 2009-12-03 デピュイ・スパイン・インコーポレイテッドDePuy Spine,Inc. Mixing equipment
JP2012029855A (en) * 2010-07-30 2012-02-16 Asahi Kasei Kuraray Medical Co Ltd Cell treatment system
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JP2014018479A (en) * 2012-07-19 2014-02-03 Okayama Univ Method for inspecting adaptability of denture base and injection tool used for the method
US8809418B2 (en) 2004-03-21 2014-08-19 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
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US8956368B2 (en) 2003-06-17 2015-02-17 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
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US9642932B2 (en) 2006-09-14 2017-05-09 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
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US8992541B2 (en) 2003-03-14 2015-03-31 DePuy Synthes Products, LLC Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US9839460B2 (en) 2003-03-31 2017-12-12 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US10039585B2 (en) 2003-06-17 2018-08-07 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US9504508B2 (en) 2003-06-17 2016-11-29 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US8956368B2 (en) 2003-06-17 2015-02-17 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US10111697B2 (en) 2003-09-26 2018-10-30 DePuy Synthes Products, Inc. Device for delivering viscous material
US9750840B2 (en) 2004-03-21 2017-09-05 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US8809418B2 (en) 2004-03-21 2014-08-19 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
JP2008529663A (en) * 2005-02-09 2008-08-07 チルドレンズ メディカル センター コーポレイションChildren’S Medical Center Corporation Mixing and supplying device fluid for tissue recovery
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US9259696B2 (en) 2005-11-22 2016-02-16 DePuy Synthes Products, Inc. Mixing apparatus having central and planetary mixing elements
JP2009542427A (en) * 2006-07-06 2009-12-03 デピュイ・スパイン・インコーポレイテッドDePuy Spine,Inc. Mixing equipment
US9642932B2 (en) 2006-09-14 2017-05-09 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US8950929B2 (en) 2006-10-19 2015-02-10 DePuy Synthes Products, LLC Fluid delivery system
JP2012029855A (en) * 2010-07-30 2012-02-16 Asahi Kasei Kuraray Medical Co Ltd Cell treatment system
US8992071B2 (en) 2012-05-07 2015-03-31 Heraeus Medical Gmbh Mixing device for multi-component systems
JP2013240582A (en) * 2012-05-07 2013-12-05 Heraeus Medical Gmbh Mixing device for multi-component systems
JP2014018479A (en) * 2012-07-19 2014-02-03 Okayama Univ Method for inspecting adaptability of denture base and injection tool used for the method
WO2016144868A1 (en) * 2015-03-06 2016-09-15 Dentsply Sirona Inc. Dental material delivery system
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