JP2003531180A5 - - Google Patents
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- Publication number
- JP2003531180A5 JP2003531180A5 JP2001577990A JP2001577990A JP2003531180A5 JP 2003531180 A5 JP2003531180 A5 JP 2003531180A5 JP 2001577990 A JP2001577990 A JP 2001577990A JP 2001577990 A JP2001577990 A JP 2001577990A JP 2003531180 A5 JP2003531180 A5 JP 2003531180A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor agonist
- composition according
- ester
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/552,823 | 2000-04-20 | ||
| US09/552,823 US20030114482A1 (en) | 1999-12-15 | 2000-04-20 | Use of retinoid receptor antagonists or agonists in the treatment of cartilage and bone pathologies |
| PCT/US2001/012742 WO2001080894A2 (en) | 2000-04-20 | 2001-04-19 | Use of retinoid receptor antagonists or agonists in the treatment of cartilage and bone pathologies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003531180A JP2003531180A (ja) | 2003-10-21 |
| JP2003531180A5 true JP2003531180A5 (https=) | 2008-06-05 |
Family
ID=24206947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001577990A Pending JP2003531180A (ja) | 2000-04-20 | 2001-04-19 | 軟骨および骨の疾患の治療におけるレチノイド受容体拮抗薬または作用薬の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20030114482A1 (https=) |
| EP (1) | EP1274456B1 (https=) |
| JP (1) | JP2003531180A (https=) |
| AT (1) | ATE285794T1 (https=) |
| AU (3) | AU5548801A (https=) |
| CA (1) | CA2407021A1 (https=) |
| DE (1) | DE60108094T2 (https=) |
| HK (1) | HK1053053B (https=) |
| WO (1) | WO2001080894A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007518719A (ja) * | 2003-12-26 | 2007-07-12 | アラーガン インコーポレイテッド | ＲＡＲγレチノイド受容体アンタゴニスト活性を有する二置換カルコンオキシム |
| JP2007070281A (ja) * | 2005-09-06 | 2007-03-22 | Matsumoto Shika Univ | レチノイドｘ受容体関連化合物を用いた骨粗鬆症の治療剤 |
| EP1959945B1 (en) * | 2005-12-13 | 2014-12-03 | McGill University | Fenretinide for correcting a lipid imbalance in a subject |
| US20090209601A1 (en) * | 2008-02-15 | 2009-08-20 | Wyeth | Use of rxr agonists for the treatment of osteoarthritis |
| EP3721880B1 (en) | 2010-09-01 | 2022-02-02 | Thomas Jefferson University | Composition and method for muscle repair and regeneration |
| US20140094512A1 (en) * | 2012-10-02 | 2014-04-03 | Nikolas Gunkel | Method of modulating the degree of adipose tissue deposited intramuscularly |
| US9492431B2 (en) | 2012-11-08 | 2016-11-15 | Yamaguchi University | Therapeutic agent for keratoconjunctive disorders |
| US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
| ES2694831T3 (es) | 2013-05-22 | 2018-12-27 | Yamaguchi University | Inhibidor para trastornos retinocoroideos |
| JP7023868B2 (ja) | 2016-06-08 | 2022-02-22 | クレメンティア ファーマシューティカルズ，インコーポレイテッド | 異所性骨化を治療するための方法 |
| CA3043807A1 (en) | 2016-11-16 | 2018-05-24 | Clementia Pharmaceuticals Inc. | Methods for treating multiple osteochondroma (mo) |
| AU2018300150A1 (en) | 2017-07-11 | 2020-01-30 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| WO2020146682A1 (en) | 2019-01-10 | 2020-07-16 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| US12440481B2 (en) | 2019-01-10 | 2025-10-14 | Vertex Pharmaceuticals Incorporated | Esters and carbamates as modulators of sodium channels |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4621100A (en) * | 1981-09-25 | 1986-11-04 | The Upjohn Company | Treatment of osteoporosis with prostaglandins |
| US5977125A (en) * | 1994-10-31 | 1999-11-02 | Eisai Co., Ltd. | Mono-or polyenic carboxylic acid derivatives |
| US5514825A (en) * | 1994-12-29 | 1996-05-07 | Allergan, Inc. | Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity |
| US5648514A (en) * | 1994-12-29 | 1997-07-15 | Allergan | Substituted acetylenes having retinoid-like biological activity |
| DE19501032A1 (de) * | 1995-01-14 | 1996-07-18 | Max Delbrueck Centrum | Mittel zur Behandlung von rheumatischen Erkrankungen |
| US5776699A (en) * | 1995-09-01 | 1998-07-07 | Allergan, Inc. | Method of identifying negative hormone and/or antagonist activities |
| US5877207A (en) * | 1996-03-11 | 1999-03-02 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
| CN1255396C (zh) * | 1996-03-18 | 2006-05-10 | 卫材株式会社 | 含有稠环的羧酸衍生物 |
| US5808124A (en) * | 1996-06-21 | 1998-09-15 | Allergan | O- or S-substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5773594A (en) * | 1996-06-21 | 1998-06-30 | Allergan | Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5763635A (en) * | 1996-06-21 | 1998-06-09 | Allergan | Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity |
| US5739338A (en) * | 1996-11-05 | 1998-04-14 | Allergan | N-aryl substituted tetrahydroquinolines having retinoid agonist, retinoid antagonist or retinoid inverse agonist type biological activity |
| US5728846A (en) * | 1996-12-12 | 1998-03-17 | Allergan | Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives |
| US5760276A (en) * | 1997-03-06 | 1998-06-02 | Allergan | Aryl-and heteroarylcyclohexenyl substituted alkenes having retinoid agonist, antagonist or inverse agonist type biological activity |
| US5962707A (en) * | 1998-08-18 | 1999-10-05 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D3 compounds with calcemic activity |
| CA2254429A1 (en) * | 1998-11-19 | 2000-05-19 | Tully Michael Underhill | Compositions for promoting chondrogenesis |
| DE19910246A1 (de) * | 1999-03-08 | 2000-09-28 | Bayer Ag | Trennfreundliche Polyurethan-Formschaum-Systeme |
| CA2402413A1 (en) * | 2000-03-14 | 2001-09-20 | The University Of Western Ontario | Compositions and methods for affecting osteogenesis |
-
2000
- 2000-04-20 US US09/552,823 patent/US20030114482A1/en not_active Abandoned
-
2001
- 2001-04-19 WO PCT/US2001/012742 patent/WO2001080894A2/en not_active Ceased
- 2001-04-19 EP EP01928654A patent/EP1274456B1/en not_active Expired - Lifetime
- 2001-04-19 AU AU5548801A patent/AU5548801A/xx active Pending
- 2001-04-19 DE DE60108094T patent/DE60108094T2/de not_active Expired - Fee Related
- 2001-04-19 HK HK03105084.3A patent/HK1053053B/en not_active IP Right Cessation
- 2001-04-19 AT AT01928654T patent/ATE285794T1/de not_active IP Right Cessation
- 2001-04-19 AU AU2001255488A patent/AU2001255488B2/en not_active Ceased
- 2001-04-19 CA CA002407021A patent/CA2407021A1/en not_active Abandoned
- 2001-04-19 JP JP2001577990A patent/JP2003531180A/ja active Pending
-
2006
- 2006-10-27 AU AU2006233216A patent/AU2006233216A1/en not_active Abandoned
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