JP2003512836A - タンキラーゼh、細胞周期に関わる組成物および使用法 - Google Patents

タンキラーゼh、細胞周期に関わる組成物および使用法

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Publication number
JP2003512836A
JP2003512836A JP2001533970A JP2001533970A JP2003512836A JP 2003512836 A JP2003512836 A JP 2003512836A JP 2001533970 A JP2001533970 A JP 2001533970A JP 2001533970 A JP2001533970 A JP 2001533970A JP 2003512836 A JP2003512836 A JP 2003512836A
Authority
JP
Japan
Prior art keywords
cell cycle
cell
protein
nucleic acid
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001533970A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003512836A5 (enExample
Inventor
ルオ・イン
エバ・チャン
シュ・シアン
ベティ・フアン
バレリア・オソフスカヤ
Original Assignee
ライジェル・ファーマシューティカルズ・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ライジェル・ファーマシューティカルズ・インコーポレイテッド filed Critical ライジェル・ファーマシューティカルズ・インコーポレイテッド
Publication of JP2003512836A publication Critical patent/JP2003512836A/ja
Publication of JP2003512836A5 publication Critical patent/JP2003512836A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2001533970A 1999-10-25 2000-10-25 タンキラーゼh、細胞周期に関わる組成物および使用法 Pending JP2003512836A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/427,154 US6589725B1 (en) 1999-10-25 1999-10-25 Tankyrase H, compositions involved in the cell cycle and methods of use
US09/427,154 1999-10-25
PCT/US2000/041528 WO2001030987A2 (en) 1999-10-25 2000-10-25 Tankyrase h, compositions involved in the cell cycle and methods of use

Publications (2)

Publication Number Publication Date
JP2003512836A true JP2003512836A (ja) 2003-04-08
JP2003512836A5 JP2003512836A5 (enExample) 2007-12-06

Family

ID=23693704

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001533970A Pending JP2003512836A (ja) 1999-10-25 2000-10-25 タンキラーゼh、細胞周期に関わる組成物および使用法

Country Status (6)

Country Link
US (2) US6589725B1 (enExample)
EP (1) EP1238063A2 (enExample)
JP (1) JP2003512836A (enExample)
AU (1) AU2470801A (enExample)
CA (1) CA2388332A1 (enExample)
WO (1) WO2001030987A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000061813A1 (en) 1999-04-09 2000-10-19 Geron Corporation A second mammalian tankyrase
US6887675B1 (en) * 1999-10-25 2005-05-03 Rigel Pharmaceuticals, Inc. Tankyrase H, compositions involved in the cell cycle and methods of use
US20020142334A1 (en) * 2001-01-30 2002-10-03 Brown Janice A. Methods of detecting poly(ADP-ribose) polymerase enzymatic activity
US7059920B2 (en) * 2003-06-25 2006-06-13 International Connectors & Cable Corp. Spring clip connector
EP1836320A2 (en) * 2005-01-07 2007-09-26 Arqule, Inc. Compositions for modulation of parp and methods for screening for same
WO2009027650A1 (en) * 2007-08-24 2009-03-05 The Institute Of Cancer: Royal Cancer Hospital Materials and methods for exploiting synthetic lethality in brca-associated cancers

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006123A1 (en) 1991-09-20 1993-04-01 Fred Hutchinson Cancer Research Center Human cyclin e
US5726025A (en) 1995-04-20 1998-03-10 President And Fellows Of Harvard College Assay and reagents for detecting inhibitors of ubiquitin-dependent degradation of cell cycle regulatory proteins
AU6956798A (en) 1997-04-10 1998-10-30 Genetics Institute Inc. Secreted expressed sequence tags (sests)
AUPO938897A0 (en) 1997-09-23 1997-10-16 Garvan Institute Of Medical Research A potential effector for the grb7 family of signalling proteins
US6277613B1 (en) 1998-06-10 2001-08-21 The Rockefeller University TRF1 binding protein, methods of use thereof
US6387902B1 (en) 1998-12-31 2002-05-14 Guilford Pharmaceuticals, Inc. Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP
PL210415B1 (pl) 1999-01-11 2012-01-31 Agouron Pharma Pochodne indolu, środek farmaceutyczny i zastosowanie pochodnych indolu
WO2000061813A1 (en) 1999-04-09 2000-10-19 Geron Corporation A second mammalian tankyrase
WO2000072021A2 (en) 1999-05-26 2000-11-30 Ludwig Institute For Cancer Research Cancer associated antigens and uses therefor
WO2000077225A1 (en) 1999-06-11 2000-12-21 Whitehead Institute For Biomedical Research A novel insulin signaling molecule
EP1192259A1 (en) 1999-06-29 2002-04-03 Icos Corporation Tankyrase2 materials and methods
US6455290B1 (en) 1999-07-09 2002-09-24 Pharmacia Italia S.P.A. Tankyrase homolog protein (THP), nucleic acids, and methods related to the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5002020410, SMITH S, SCIENCE, 19981120, V282 N5393, P1484−1487, US, AMERICAN ASSOC FOR THE ADVANCEMENT OF SCIENCE *

Also Published As

Publication number Publication date
WO2001030987A3 (en) 2001-12-13
EP1238063A2 (en) 2002-09-11
US6589725B1 (en) 2003-07-08
US6617102B1 (en) 2003-09-09
WO2001030987A2 (en) 2001-05-03
CA2388332A1 (en) 2001-05-03
AU2470801A (en) 2001-05-08

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