JP2003501396A - 出血性ショックを処置するためのインターロイキン−11の使用 - Google Patents

出血性ショックを処置するためのインターロイキン−11の使用

Info

Publication number
JP2003501396A
JP2003501396A JP2001501241A JP2001501241A JP2003501396A JP 2003501396 A JP2003501396 A JP 2003501396A JP 2001501241 A JP2001501241 A JP 2001501241A JP 2001501241 A JP2001501241 A JP 2001501241A JP 2003501396 A JP2003501396 A JP 2003501396A
Authority
JP
Japan
Prior art keywords
interleukin
rhil
hemorrhagic shock
administered
shock
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001501241A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003501396A5 (enExample
Inventor
マシュー ポラック,
ジェイムス シー. ジュニア ケイス,
Original Assignee
ジェネティックス・インスチチュート・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェネティックス・インスチチュート・インコーポレーテッド filed Critical ジェネティックス・インスチチュート・インコーポレーテッド
Publication of JP2003501396A publication Critical patent/JP2003501396A/ja
Publication of JP2003501396A5 publication Critical patent/JP2003501396A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2073IL-11
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2001501241A 1999-06-08 2000-06-08 出血性ショックを処置するためのインターロイキン−11の使用 Pending JP2003501396A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13805499P 1999-06-08 1999-06-08
US60/138,054 1999-06-08
PCT/US2000/015737 WO2000074707A2 (en) 1999-06-08 2000-06-08 Use of interleukin-11 to treat hemorrhagic shock

Publications (2)

Publication Number Publication Date
JP2003501396A true JP2003501396A (ja) 2003-01-14
JP2003501396A5 JP2003501396A5 (enExample) 2007-08-16

Family

ID=22480226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001501241A Pending JP2003501396A (ja) 1999-06-08 2000-06-08 出血性ショックを処置するためのインターロイキン−11の使用

Country Status (9)

Country Link
EP (1) EP1185292B1 (enExample)
JP (1) JP2003501396A (enExample)
CN (1) CN1355707A (enExample)
AT (1) ATE294590T1 (enExample)
AU (1) AU5328800A (enExample)
CA (1) CA2376358A1 (enExample)
DE (1) DE60019921T2 (enExample)
MX (1) MXPA01012663A (enExample)
WO (1) WO2000074707A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6953777B2 (en) 1999-03-11 2005-10-11 Genetics Indtitute LLC Use of interleukin-11 to prevent immune-mediated cytotoxicity
US6982080B2 (en) 2002-03-15 2006-01-03 Wyeth Hydroxyethyl starch—containing polypeptide compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08500838A (ja) * 1992-09-02 1996-01-30 ジェネティックス・インスティテュート・インコーポレイテッド 細胞損傷または枯渇の治療法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08500838A (ja) * 1992-09-02 1996-01-30 ジェネティックス・インスティテュート・インコーポレイテッド 細胞損傷または枯渇の治療法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6010024815, Rollwagen,F.M. et al., "IL−6 rescues enterocytes from hemorrhage induced apoptosis in vivo and in vitro by a bcl−2 mediated", Clin. Immunol. Immunopathol, 199812, Vol.89,No.3, P.205−213 *
JPN7010001387, Barton,B.E. et al., "Interleukins 6 and 11 protect mice from mortality in a staphylococcal enterotoxin−induced toxic shoc", Infect. Immun., 199603, Vol.64,No.3, P.714−718 *

Also Published As

Publication number Publication date
DE60019921T2 (de) 2006-02-16
MXPA01012663A (es) 2004-10-14
CN1355707A (zh) 2002-06-26
EP1185292A2 (en) 2002-03-13
EP1185292B1 (en) 2005-05-04
DE60019921D1 (de) 2005-06-09
AU5328800A (en) 2000-12-28
WO2000074707A3 (en) 2001-04-19
CA2376358A1 (en) 2000-12-14
ATE294590T1 (de) 2005-05-15
WO2000074707A2 (en) 2000-12-14

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