JP2003246730A5 - - Google Patents
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- Publication number
- JP2003246730A5 JP2003246730A5 JP2002046613A JP2002046613A JP2003246730A5 JP 2003246730 A5 JP2003246730 A5 JP 2003246730A5 JP 2002046613 A JP2002046613 A JP 2002046613A JP 2002046613 A JP2002046613 A JP 2002046613A JP 2003246730 A5 JP2003246730 A5 JP 2003246730A5
- Authority
- JP
- Japan
- Prior art keywords
- tryptase
- guanidinobenzoate
- amidino
- mesylate
- naphthyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical group CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 3
- 229940122598 Tryptase inhibitor Drugs 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- 239000002750 tryptase inhibitor Substances 0.000 claims 3
- 102000001400 Tryptase Human genes 0.000 claims 2
- 108060005989 Tryptase Proteins 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 208000005615 Interstitial Cystitis Diseases 0.000 claims 1
- 102000032628 PAR-2 Receptor Human genes 0.000 claims 1
- 108010070503 PAR-2 Receptor Proteins 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 208000003251 Pruritus Diseases 0.000 claims 1
- 206010037423 Pulmonary oedema Diseases 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 1
- 208000005333 pulmonary edema Diseases 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 230000008728 vascular permeability Effects 0.000 claims 1
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002046613A JP2003246730A (ja) | 2002-02-22 | 2002-02-22 | トリプターゼ阻害剤 |
| AU2003211540A AU2003211540A1 (en) | 2002-02-22 | 2003-02-19 | Medicinal compositions for inhibiting tryptase |
| PCT/JP2003/001814 WO2003070235A1 (fr) | 2002-02-22 | 2003-02-19 | Compositions medicinales inhibant les tryptases |
| TW092103438A TW200306811A (en) | 2002-02-22 | 2003-02-19 | Medicinal compositions for inhibiting tryptase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002046613A JP2003246730A (ja) | 2002-02-22 | 2002-02-22 | トリプターゼ阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003246730A JP2003246730A (ja) | 2003-09-02 |
| JP2003246730A5 true JP2003246730A5 (enrdf_load_stackoverflow) | 2005-08-25 |
Family
ID=27750646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002046613A Pending JP2003246730A (ja) | 2002-02-22 | 2002-02-22 | トリプターゼ阻害剤 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP2003246730A (enrdf_load_stackoverflow) |
| AU (1) | AU2003211540A1 (enrdf_load_stackoverflow) |
| TW (1) | TW200306811A (enrdf_load_stackoverflow) |
| WO (1) | WO2003070235A1 (enrdf_load_stackoverflow) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005120491A1 (ja) * | 2004-06-14 | 2005-12-22 | Torii Pharmaceutical Co., Ltd. | 炎症性腸疾患の治療薬又は予防薬 |
| GB0507577D0 (en) * | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| EP2119440A1 (en) * | 2005-05-17 | 2009-11-18 | Santen Pharmaceutical Co., Ltd. | Amidino derivatives for use in the prevention or treatment of retinitis pigmentosa and Leber's disease |
| JP2007186457A (ja) * | 2006-01-13 | 2007-07-26 | Ichimaru Pharcos Co Ltd | トリプターゼ活性阻害剤およびその利用 |
| GB2445920A (en) * | 2007-01-25 | 2008-07-30 | Mucokinetica Ltd | Amidino compounds for treatment of respiratory disease |
| CN106580961A (zh) * | 2016-12-07 | 2017-04-26 | 郑州仁宏医药科技有限公司 | 一种用于治疗特发性肺纤维化的西药组合及其应用 |
| JP7418337B2 (ja) * | 2018-02-09 | 2024-01-19 | ジェネンテック， インコーポレイテッド | マスト細胞媒介性炎症性疾患の治療法及び診断法 |
| CA3174067A1 (en) * | 2020-03-31 | 2021-10-07 | Lynn Kirkpatrick | Methods for treating viral infections with nafamostat |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5753454A (en) * | 1980-09-16 | 1982-03-30 | Torii Yakuhin Kk | Guanidinobenzoate and anticomplementary agent |
| EP0893437A4 (en) * | 1996-04-10 | 2000-12-27 | Ono Pharmaceutical Co | GUANIDINO TRYPTASE INHIBITOR |
-
2002
- 2002-02-22 JP JP2002046613A patent/JP2003246730A/ja active Pending
-
2003
- 2003-02-19 WO PCT/JP2003/001814 patent/WO2003070235A1/ja active Application Filing
- 2003-02-19 TW TW092103438A patent/TW200306811A/zh unknown
- 2003-02-19 AU AU2003211540A patent/AU2003211540A1/en not_active Abandoned