JP2003213022A - Simple method for producing iodine-including article and iodine gas sustained releaser having resistance to water and disinfection system using the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method of simply and safely producing iodine-including articles, e.g. fiber sheets having iodine adsorbed on the fibers so that it may be used for disinfection and provide an iodine gas sustained releaser that can be used in water. <P>SOLUTION: A high molecular compound to which iodine is adsorbed is used as an iodine resource and the iodine gas liberated from the iodine resource is utilized to allow articles, e.g. fiber sheets or the like to adsorb iodine. In another embodiment, the high molecular compound to which iodine is adsorbed is covered with a sheet that permeates the gas but does not permeate liquid water whereby water is inhibited from intrusion into the iodine gas sustained releaser and the iodine gas may be slowly released into water without coming into contact with water. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a simple method for producing an iodine-containing article using a polymer compound having iodine adsorbed as an iodine gas generation source, an iodine gas sustained release tool which can be used in the presence of water, and uses thereof. It is about.

[0002]

2. Description of the Related Art Hitherto, attempts have been made to adsorb iodine to a fibrous sheet-like material to exert a bactericidal effect. For example, Japanese Patent Application Laid-Open No. 1-124688 discloses a bactericidal fabric containing an iodo complex adduct, and fibers such as nylon and acrylic are described as such a fabric. Further, JP-A No. 11-50376 discloses a vinylon non-woven fabric carrying an iodine compound. In all of these, a fiber sheet material is dipped or applied in an iodine compound solution to adsorb iodine to the fiber. However, the treatment of the fibrous sheet material using the iodine solution has a problem that the waste liquid containing iodine is required because the operation is complicated.

On the other hand, in hospitals and the like, disinfection of fingers and utensils is extremely important to prevent infection by microorganisms, but commonly used biguanide fungicides, quaternary ammonium salt fungicides, polyvinylpyrrolidone and iodine. The complex, alcohol and the like have problems of rough hands, antibacterial spectrum and usability, and are not satisfactory in all aspects. Therefore, development of a further excellent disinfectant or disinfection system is desired.

Further, in order to protect the faucet for aseptic water for hand washing used in a hospital operating room or the like from reverse contamination of microorganisms, a method of inserting iodine-adsorbed plastic beads into the faucet and utilizing iodine eluted from the beads is performed. It is being appreciated. This method aims to prevent contamination from the faucet by disinfecting the water remaining in the faucet, but during the use of the device there is no concern of microbial contamination due to the water flowing out, so during that time iodine Need not be emitted. Therefore, limiting the release of iodine during use extends the life of the beads. However, in the conventional method, since the beads come into direct contact with water, there is a drawback that iodine is wasted by the heated water when the apparatus is used.

Conventionally, ultraviolet rays and formaldehyde gas have been often used in hospitals and the like for disinfecting articles, but there have been problems such as the need for expensive equipment and the danger to the human body.

Furthermore, it cannot be said that there is a sufficiently simple and reliable method for disinfecting a hospital room, a floor, etc. In addition, in disinfection in which an object is immersed in a liquid agent, disinfection performed by a general user like a contact lens is not performed. Safety, certainty and simplicity are required, but the ideal has not yet emerged.

[0007]

The present invention has been made under the circumstances described above, and the first object of the present invention is to provide an iodine-containing article which can be easily and safely manufactured for disinfection in a hospital or at home. In particular, it is to provide a method for producing a fibrous sheet material containing iodine. A second object is to provide a water-resistant iodine sustained-release device which is useful for various disinfection and which can be used even in the presence of water. A third object is to provide a novel means in the field of disinfection systems such as the prevention of contamination of a sterile water faucet and the disinfection of contact lenses using iodine gas.

[0008]

Means for Solving the Problems As a result of various studies to achieve the above object, the present inventors achieved the first object by utilizing a polymer compound having adsorbed iodine as an iodine gas generating source. In addition, the second object can be achieved by coating the above-mentioned polymer compound having adsorbed iodine with a sheet-like material that is permeable to gas and substantially impermeable to liquid water. The application has succeeded in achieving the third object and has reached the present invention.

That is, the gist of the first invention is a method for producing an iodine-containing article, which is characterized in that a iodine-adsorbed polymer compound is used as an iodine gas generation source to adsorb iodine to the article. As the iodine-adsorbed polymer compound, ABS resin, AS resin, ethylene / vinyl alcohol copolymer, polyamide, polyvinyl alcohol, beads selected from the group consisting of formalized polyvinyl alcohol, powder, fiber, film, fabric, Nonwoven fabric or gel is used.

A fiber sheet material containing a polyamide epichlorohydrin resin or a polyamine / polyamide epichlorohydrin resin is preferably used as the article for adsorbing iodine gas from the iodine-adsorbed polymer compound. The iodine-containing fiber sheet material is preferably used. It is possible to provide a powerful disinfection method by using it after wetting it with water.

A second aspect of the present invention is a water-resistant iodine gas sustained-release device characterized in that a polymeric compound having adsorbed iodine is coated with a sheet-like material which is permeable to gas and substantially impermeable to liquid water. The summary will be given. As an embodiment thereof, a covering material such as a polytetrafluoroethylene-based or polyolefin-based porous film, a non-woven fabric made of special polyethylene ultrafine fibers, or a non-porous polyolefin-based film having gas permeability is preferably used.

A third aspect of the present invention is an iodine gas generated from a water-resistant iodine gas sustained-release device, which is obtained by coating a polymeric compound having adsorbed iodine with a sheet-like material that is gas-permeable and substantially liquid-water impermeable. The gist is a disinfection system characterized by disinfecting the surrounding air and / or liquid and articles existing in the air and / or liquid by using.

Specific examples of the above disinfection system include prevention of contamination of a sterile water faucet and disinfection of contact lenses.
In the prevention of contamination of the sterile water faucet, since water does not enter the interior of the water resistant iodine gas sustained release device, the polymer compound that adsorbed iodine does not come into contact with the hot water when the sterile water device is used, and unnecessary iodine is not used. It can prevent consumption. Further, when the device is not used, iodine gas is gradually released from the water resistant iodine gas sustained release tool, and water in the faucet can be disinfected.
When used for disinfecting a contact lens, the lens can be easily disinfected simply by immersing the water resistant iodine gas sustained release tool and the contact lens in physiological saline.

Further, in the disinfection system according to the present invention, the water-resistant iodine gas sustained-release tool is dipped in an aqueous liquid in which a compound capable of forming a complex with iodine is dissolved, and the article to be disinfected in the aqueous liquid. And a means for controlling the release of iodine gas from the water-resistant iodine sustained-release device by allowing them to coexist. As a compound capable of forming a complex with iodine, polyvinyl alcohol, polyvinylpyrrolidone, starch, dextrin, polyoxyethylene,
Preference is given to alkali metal salts of iodine and nonionic surfactants having a polyoxyethylene chain. By adding these compounds capable of forming a complex with iodine, the iodine as a sustained-release agent allows the gas as a coating material to permeate through a sheet material that does not substantially permeate liquid water to the outside liquid. The amount of iodine gas released to the remarkably increases, and the disinfecting effect can be enhanced.

Incidentally, JP-A-9-67217, JP-A-9-67217
No. 122655 and Japanese Patent Laid-Open No. 10-165960 disclose an antibacterial composition in which iodine is adsorbed to plastic and brought into contact with water to gradually release iodine into water. A new method was developed in which iodine is adsorbed on the iodine and used as a sustained-release agent for iodine gas without contacting it with water.

[0016]

BEST MODE FOR CARRYING OUT THE INVENTION In the first aspect of the present invention, as the iodine-adsorbed polymer compound used as an iodine gas source, a iodine-adsorbed polymer compound is used. Examples of plastics having iodine adsorption are ABS resin, AS resin, ethylene / vinyl alcohol copolymer (EVOH), ethylene / vinyl acetate copolymer, polyamide, polyacrylonitrile,
Acrylonitrile / vinyl chloride copolymer resin, polyurethane resin, cellulose acetate resin, polyvinyl alcohol,
Formalized polyvinyl alcohol, polyester, polyethylene oxide resin, starch, polyvinylpyrrolidone copolymer (for example, vinylpyrrolidone / methyl methacrylate copolymer) and the like are used. Further, even a resin having a poor iodine adsorption property can be used by mixing and molding the above iodine adsorption resin.

Among the above-mentioned plastics, ABS resin, AS resin, ethylene-vinyl alcohol copolymer (EVOH) are particularly desirable because of their excellent iodine adsorption.
Is. Generally, what is marketed as an ABS resin has an acrylonitrile component of 20 to 30% by weight, a styrene component of 40 to 70% by weight, and a butadiene component of 10 to 3%.
Although it is about 0% by weight, any of them can be used in the present invention. As the EVOH resin, it is preferable to use one having a content of ethylene in the copolymer of 20 to 50 mol%. As commercial products, any of various Soarnol products manufactured by Nippon Synthetic Chemical Industry Co., Ltd. and various EVAL products manufactured by Kuraray Co., Ltd. can be used.

As the form of the polymer compound having adsorbed iodine, various forms such as beads, powder, fibers, woven or non-woven fabric, film or gel can be used. Also, a molded product obtained by thermoforming such as injection molding, extrusion molding, compression molding or the like can be used. The preferred form varies depending on the method of use, application, etc., but in terms of ease of the iodine adsorption step, beads or powders are preferred. As a bead-shaped form, a pellet for injection molding of a plastic material is advantageous because a commercially available product can be used as it is. It is also possible to use pellets for injection molding which are crushed into fine pieces.

In order to obtain a polymer compound having adsorbed iodine from an iodine-adsorbing polymer compound material (hereinafter abbreviated as polymer material), it is necessary to adsorb iodine to the polymer material. For adsorption of iodine, a liquid phase method in which a polymer material is immersed in an iodine solution may be used, but a gas phase method has better operability,
This is advantageous because it is easy to increase the adsorption amount and no waste liquid is produced. The method of adsorbing iodine on the polymer material is described in detail in JP-A-10-165960 and the like. That is, in the vapor phase adsorption of iodine, the polymer material and solid iodine are put in a closed container, and the temperature is 50 ° C to 110 ° C.
It is carried out by heating to ℃. Heating is performed until all solid iodine is adsorbed on the polymer material, but the time depends on the type and form of the polymer material and the amount of iodine to be adsorbed.

The amount of iodine adsorbed on the polymer material is preferably 5 to 200% by weight. A material having a large surface area such as powder may require a relatively small amount of iodine adsorption, and a material having a small surface area requires a relatively large amount. A desirable adsorption amount is 10 to 200% by weight, particularly preferably 30 to 150% by weight (based on the weight of plastic) in the case of a beaded form. In the case of powder, iodine adsorption amount is 10-100
About wt% (weight of plastic) is suitable.

For example, in the case of adsorbing 100% by weight of iodine to the ABS resin molding pellets, the resin pellets are mixed with an equal amount of solid iodine in a closed container, and 50 to 1 is mixed.
Iodine can be completely adsorbed by heating at 00 ° C for 1 to 10 hours.

If iodine is adsorbed on the polymer material and then heat treatment is carried out at a temperature higher than the temperature at the time of adsorption, the iodine penetrates further into the polymer material. In this case, the sustained release rate of iodine from the polymer compound that adsorbed iodine decreases,
Iodine can be gradually released for a longer time. The sustained release rate of iodine can be adjusted by the amount of iodine adsorbed and the heat treatment conditions. When the polymer material is a fine powder, iodine penetrates into the interior without heat treatment, but the release of iodine is fast, so the time for sustained release tends to be short.

As the polymer compound adsorbing iodine,
In addition to the one in which iodine is adsorbed on the polymer material as described above, a gel of a hydrophilic polymer compound impregnated with an iodine solution can be used.

In the present invention, an iodine-containing article can be easily produced by causing the iodine-adsorbing article to adsorb iodine by using the iodine-adsorbing polymer compound as an iodine gas generating source. Here, the iodine-adsorptive article means an article having an ability to adsorb iodine.

As the iodine-adsorptive article, cellulose,
Polymer compounds such as polyacrylonitrile-based polymers, polyamides, polyesters, ethylene / vinyl alcohol copolymers, polyvinyl alcohols, and partially formalized polyvinyl alcohols are used, but polyolefin-based resins, fluorine-based resins and the like have poor iodine adsorption. Glass, pottery, etc. do not have adsorptivity.

As a specific example of a method for producing an iodine-containing article by adsorbing iodine to an iodine-adsorptive article by using a polymer compound that has adsorbed iodine as an iodine gas generating source, one example of a method of attaching and detaching a packing The iodine-adsorbing article is gradually released from the iodine-adsorbing polymer compound by simply placing the iodine-adsorbing polymer compound and the iodine-adsorbing article in a closed container having a free lid and leaving the iodine-adsorbing article. Iodine-containing articles are automatically produced by adsorbing gas.

The iodine-containing article may be manufactured at room temperature or may be heated. When heated, the amount of iodine gas generated increases and iodine can be adsorbed to the iodine-adsorptive article in a short time. The temperature when heating is 30 to 60
C. is preferable. The time for adsorbing iodine from the iodine gas sustained-release agent on the iodine-adsorptive article varies depending on the form of the iodine-adsorptive article, the iodine sustained-release amount of the iodine-adsorptive agent, and the like, but it is usually 1 hour to 1 month at room temperature. 40-50 ° C
When heated to 1, the time can be shortened to a fraction.

When the above-mentioned polymer compound adsorbing iodine is in the form of beads or powder, it should be used after being covered with a material having iodine resistance, such as by using a nonwoven fabric such as a polyolefin fiber and putting it in a bag such as a tay bag. Can be done.

According to the method for producing an iodine-containing article of the present invention, the iodine-containing article is obtained in a gas phase by using a polymer compound having adsorbed iodine as a source of iodine and coexisting with the iodine-adsorptive article. Therefore, the iodine-containing article can be manufactured much more easily than the conventional method. That is, since the polymer compound adsorbing iodine used in the present invention does not generate iodine gas violently like solid iodine and gently releases iodine slowly, it is easy to handle and handled in an open ordinary room. You can Further, as described above, it is easy to adjust the sustained release amount of iodine depending on the production conditions. Also, since it is not necessary to use water, there is no waste liquid and there is no need to worry about exhaust. Therefore, according to the method of the present invention, it is possible to easily and safely prepare an iodine-adsorbing article for disinfection even in a hospital room or at home.

The iodine-containing article produced by the method for producing an iodine-containing article of the present invention can be used as an antibacterial article or material. It is also useful for disinfection.

Among the iodine-containing articles produced by the method of the present invention, a particularly useful form is a fibrous sheet. The fibrous sheet may be paper, non-woven fabric, woven fabric or knitted fabric. In order to produce the iodine-containing fiber sheet material, it is sufficient that the fibers constituting the sheet material have the ability to adsorb iodine. Cellulosic fibers (cotton, regenerated cellulose fibers, acetate fibers), polyamides, polyesters, and acrylic fibers all have iodine adsorption ability. In the production of the iodine-containing fiber sheet material, for example, the polymer compound having adsorbed iodine is stored in a closed container having a detachable lid, and the iodine-adsorbing fiber sheet material is put in the container. When the fibrous sheet material adsorbs sufficient iodine under the following conditions, it can be taken out of the container and used as an iodine-containing fibrous sheet material. In this case, it is necessary to adjust the necessary adsorption time depending on the amount of the polymer compound adsorbing iodine and the iodine gas sustained release rate.

It is preferable to use hydrophilic cellulosic fibers as the fibrous sheet material for the purpose of disinfection. For this reason, cotton gauze, regenerated cellulose-based nonwoven fabric, and the like can be used, but since these have relatively low iodine adsorption capacity, adsorption takes a long time. On the other hand, when the cellulose-based fiber sheet material is treated with a polyamine / polyamide-based or polyamide epichlorohydrin-based resin, the iodine-adsorbing ability is increased and a large amount of iodine can be adsorbed in a short time.
A fibrous sheet-like material is immersed in an aqueous solution of the above resin, compressed, and then dried at 100 to 110 ° C. to crosslink with hydroxyl groups of cellulose, thereby increasing the water resistance of the sheet and simultaneously having a high iodine adsorption capacity. The thing is obtained. These epichlorohydrin resins are generally used as a wet paper strength enhancer for paper. For example, Harima Kasei Co., Ltd. "Harmide PY-410" and "Harmide PY-4".
30 ".

Tissue paper currently on the market,
The above-mentioned wet strength enhancer is usually used for paper wipers. Therefore, commercially available tissue papers and wipers can be advantageously used as materials for iodine-containing fibrous sheet materials. In particular, JK wiper, K-dry, and Kimwipe, which are commercially available from Crecia Co., Ltd., are preferable because they have excellent iodine adsorption. Commercially available tissue paper can be used, but its iodine adsorption is rather low. Among them, for example, Elmore of Kami Shoji Co., Ltd. can be used because it has relatively excellent iodine adsorption.

When a fibrous sheet material having a high iodine adsorption property is used, the time required for iodine adsorption is usually a few hours to 30 hours at room temperature. It takes more than 30 hours when using cellulose fiber alone such as cotton gauze and pure regenerated cellulose nonwoven fabric. When the temperature is raised, the time required for adsorption is shortened significantly. The amount of iodine adsorbed on the fibrous sheet is usually about 0.01% by weight to 2.5% by weight. As a disinfecting fibrous sheet material, a sufficient effect can be exhibited even at 0.5% by weight or less.

The iodine-containing fibrous sheet material can be used for various purposes, and is particularly useful for disinfecting fingers, instruments and the like. In order to use the iodine-containing fiber sheet material for the purpose of disinfection, the purpose can be achieved by wetting the iodine-containing fiber sheet material with water such as tap water and wiping fingers, articles, and the like. Further, when the iodine-containing fiber sheet material is immersed in water, iodine is eluted into the water, so that iodine water for disinfection can be easily produced. Such a disinfection method can be used in a wide range of fields such as hospitals, clinics, food industry, food preparation facilities, nursing homes and home care.

As a second invention, the iodine-adsorbed polymer compound may be coated with a non-woven fabric such as iodine-resistant synthetic fiber to be used as a sustained release tool for iodine gas for disinfecting the surrounding atmosphere and articles. I can. In this case, it may be hermetically sealed or not completely hermetically sealed. For example, by placing the iodine gas sustained release tool in an environment that requires antibacterial properties, the environment can be disinfected.

On the other hand, when the above-mentioned iodine gas sustained release tool is used in the presence of water, the polymer compound adsorbing iodine will come into contact with water, so that the water adhering to the polymer compound adsorbing iodine is admitted. It is not preferable because the iodine concentration becomes high and the surroundings are easily soiled. In addition, iodine may be wastefully consumed due to contact with water. Therefore, in order to avoid contact between the iodine gas sustained release tool and water and to adjust the amount of iodine gas released from the iodine gas sustained release tool, the polymer compound that has adsorbed iodine permeates the gas to substantially remove liquid water. It is advantageous to coat with a sheet-like material that does not permeate (hereinafter, an iodine sustained-release device coated with a polymer compound that adsorbs iodine is a sheet-like material that permeates gas and does not substantially permeate liquid water). Water-resistant iodine gas sustained release device).

Examples of the sheet-like material used in the water resistant iodine gas sustained release apparatus of the second invention which is permeable to gas and substantially impermeable to liquid water include a hydrophobic porous membrane and a hydrophobic ultrafine membrane. Specific examples include water-impermeable non-woven fabrics formed from fibers and gas-permeable non-porous films. Here, the sheet-like material that is substantially impermeable to liquid water is a sheet-like material that prevents the liquid water from entering and exiting through the sheet-like material, and a small amount of water inside the sheet during a long time. Of the present invention as long as it is difficult for the water to be released to the outside again even if a small amount of water accumulates inside the iodine gas sustained release device. It can be used for any purpose. Because a small amount of water is stored inside the iodine gas sustained release device, and even if the iodine concentration of the water increases, the water is not released to the outside and is released from the iodine sustained release device. This is because the amount of iodine gas contained therein is substantially the same as that when there is no water inside. On the other hand, when water can flow in and out through the sheet-like material that covers the iodine gas sustained release device, the water containing a high concentration of iodine inside is released to the outside of the iodine sustained release device. For this reason, the object of the present invention, which tries to prevent contact between the polymer compound having adsorbed iodine and water, cannot be achieved.

Examples of the hydrophobic porous membrane used in the water-resistant iodine gas sustained-release device of the second aspect of the invention include tetrafluoroethylene-based (including copolymer) or polyolefin-based porous membranes. Among these, for example, as a tetrafluoroethylene-based porous membrane, Nitto Denko's "Microtex",
“Goretex” manufactured by Japan Gore-Tex Co., Ltd., and the product name “Poreflon” manufactured by Sumitomo Electric Industries, Ltd. are preferably used. The pore size of the tetrafluoroethylene-based membrane is 3
Micron or less is required, preferably 2.5 micron or less,
Particularly preferably, it is 1.5 microns or less. When the pore diameter of the porous membrane is 3 μm, water does not permeate into the membrane when water is dropped, but when the coated iodine gas sustained release tool is immersed in water, water penetrates into the interior due to water pressure. Therefore, it can be used only when no water pressure is applied. If the pore size is 1.5 μm or less, preferably 1 μm or less, water vapor can permeate, but water does not enter.

As the polyolefin-based porous film, for example, “Duraguard” manufactured by Polyplastics Co., Ltd., “Yumicron” manufactured by Yuasa Battery Co., Ltd., “Espoir” manufactured by Mitsui Chemicals, Inc., etc. are preferably used. However, a membrane whose surface is made hydrophilic by corona discharge or other means cannot be used because it permeates water even if the pore size is small.

Since the hydrophobic porous membrane is generally thin and difficult to handle, it can be handled easily by laminating a nonwoven fabric such as polyethylene fiber or polypropylene fiber.

A normal non-woven fabric is permeable to iodine gas but also liquid water. However, it was found that a non-woven fabric using hydrophobic fibers with a particularly small gap between fibers is permeable to iodine gas and substantially impermeable to liquid water. A nonwoven fabric in which polyethylene ultrafine fibers having a diameter of 0.5 to 10 μm are randomly entangled to form a sheet, and the fibers are partially fused by heat to have the above-mentioned performance, and Asahi / Dyupon Flashspun Products ( Co., Ltd., and it is marketed as a brand name "Tyvek". Among these, product numbers 1059B, 1060B, 1073
B, 1422A, and 1460B have iodine gas permeability, and have a property of not substantially permeating liquid water. Also in the above-mentioned non-woven fabric, the one whose fiber surface has been hydrophilized by corona discharge or other means cannot be used because it becomes permeable to water.

In addition to the above hydrophobic porous membrane and water impermeable nonwoven fabric, a gas permeable non-porous film can be used as the coating material for the water resistant iodine gas sustained release device. A film having a property of transmitting a gas such as oxygen and carbon dioxide also has a permeability to iodine gas. Films having a relatively high iodine gas permeability and which can be used in the present invention include low density polyethylene, medium density polyethylene, linear low density polyethylene, unstretched polypropylene, and poly-4.
Methylpentene-1, ethylene / vinyl acetate copolymer,
There are ethyl cellulose and the like.

When these gas-permeable non-porous films are used as a coating material for an iodine gas sustained-release agent, iodine gas can be transmitted without transmitting liquid water at all. Further, the amount of iodine gas permeation from the iodine gas sustained release agent can be adjusted by the amount of iodine gas permeability of the film.

Low-density polyethylene, which has a relatively high iodine gas permeability and is preferably used in the present invention,
Examples thereof include linear rhodenity polyethylene, poly-4-methylpentene-1, ethylene / vinyl acetate copolymer, ethyl cellulose film and the like.

As the poly-4-methylpentene-1 film, "Opulan" manufactured by Mitsui Chemicals, Inc. is preferably used. In addition, an "OT film" of Otsuka Techno Co., Ltd. is also preferably used as a film in which poly (4-methylpentene-1) and polyethylene or polypropylene are composited. The "E series" is preferably used. In addition to this, "Polo Fresh" (Nimura Chemical Industry Co., Ltd.) has improved gas permeability of polypropylene film.
Etc.) are also preferably used.

The above-mentioned water-resistant iodine gas sustained-release tool has an advantage that even if it is wet with water, the polymer compound having adsorbed iodine, which is a source of iodine gas, does not come into direct contact with water. For example, when the iodine gas sustained-release agent is put in a bed in a hospital room, the bed is automatically disinfected by the generated iodine gas. At this time, even if the bed gets wet due to incontinence or the like, iodine does not elute into the water and the surroundings are not polluted. Further, it can be used for many purposes such as prevention of microbial contamination of floors, incontinence mat, prevention of bed slip. When the water resistant iodine gas sustained release tool of the present invention is embedded in the floor, the floor surface is automatically disinfected,
Further, by placing an iodine-adsorbing non-woven fabric or the like on the water-resistant iodine gas sustained-release tool and allowing it to contain water, it is possible to disinfect the shoe sole that walks on the floor. In this case, a method may be used in which a polymer compound having adsorbed iodine is embedded in a bed, and at least the upper surface thereof is covered with a sheet-like material that is permeable to gas and substantially impermeable to liquid water. Also, a tray-shaped container containing a polymer compound having adsorbed iodine, the upper surface of which is covered with a sheet that is permeable to gas and is substantially impermeable to liquid water, The equipment can be automatically disinfected. Further, when the iodine-containing article is produced by coexisting the iodine-adsorbed polymer compound and the iodine-adsorptive article, if the above-mentioned water resistant iodine gas sustained release tool is used as an iodine gas generation source, water may be splashed. It is possible to produce iodine-containing articles without failure even under the environment.

The above water-resistant iodine gas sustained-release device can be used by immersing it in an aqueous liquid because liquid water does not enter inside. In this case, iodine gas is gradually released into the aqueous liquid, and the aqueous liquid and / or the container in the aqueous liquid can be disinfected. JP-A-9-672
As disclosed in Japanese Patent Publication No. 16, in the case where iodine-adsorbed plastic is released or released in the presence of water to develop antibacterial properties, water-soluble impurities other than iodine are contained in the iodine-adsorbed plastic. It can be eluted. On the other hand, in the case of the iodine gas sustained-release device of the present invention, which is coated with a sheet-like material that is permeable to gas and substantially impermeable to liquid water, the polymer compound having adsorbed iodine and water Since it does not occur, only gaseous iodine is released into the aqueous liquid in which the water resistant iodine gas sustained release tool is immersed, and there is no concern that other impurities will be eluted. Therefore, the safety is extremely high.

The third invention relates to the use of a water resistant iodine gas sustained release device, one advantageous application of which is a hospital operating room,
This is to prevent the reverse contamination of microorganisms in a sterile water faucet used for hand washing in ICU and the like. In such a sterile water faucet, microorganisms adhering from the faucet side may proliferate and mix into sterile water when the sterile water device is not used. For this reason, various preventive measures using heat, ultraviolet rays, chemicals, etc. are taken to prevent microbial contamination of the faucet. One of them is a method in which iodine-adsorbed plastic beads are placed in a faucet, and the growth of microorganisms is prevented by iodine eluted from the beads when sterile water is not used. In this case, since the beads are always in direct contact with water, excess iodine elutes into the water at the start of use of the beads, and when using a sterile water device, the beads come into contact with a large amount of warm water and iodine flows out in vain. To do. Therefore, in the latter stage of use, there is a drawback that the amount of iodine adsorbed on the beads decreases and the amount of iodine released decreases.

When the above water-resistant iodine gas sustained-release device is placed in a sterile water faucet instead of the conventional iodine adsorbing beads, the polymer compound adsorbing iodine does not come into direct contact with water,
The sublimed iodine gas dissolves in water and exhibits a bactericidal action.
When aseptic water is used, the polymer compound that has adsorbed iodine does not come into direct contact with warm water, so that the wasteful consumption of iodine is reduced. Therefore, the problem of the life of the iodine sustained-release agent and the difference in the amount of dissolution between the early and late stages is improved.

In addition, since hydrous soft contact lenses are dangerous to the eyes when microorganisms grow, disinfection is obligatory. Conventionally, boiling sterilization and chemical sterilization have been carried out, but none of them was necessarily satisfactory in terms of safety or operability. Use of a water-resistant iodine gas sustained-release tool as the third invention enables simple and effective disinfection of a water-containing soft contact lens.

When the above water-resistant iodine gas sustained release tool is immersed in physiological saline, iodine gas is dissolved in the physiological saline. The amount of iodine gas generated can be adjusted by the amount of the polymer compound that has adsorbed iodine, the preparation conditions thereof and the type of the above coating material. Therefore, the iodine concentration of physiological saline can be adjusted to a concentration suitable for disinfecting contact lenses, for example, Disinfection within 3 hours Concentration 0.5 to 2 ppm Disinfection within 1 hour 1
It is possible to adjust to 10 ppm. After disinfection,
For example, by rinsing with a rinsing solution containing a reducing agent such as sodium thiosulfate, the lens can be worn safely and the coloring of the lens can be prevented. It is also possible to automatically dissipate iodine by ethylenediaminetetraacetic acid and / or a soluble salt thereof (this method is described, for example, in JP-A-10-108897). Since the water-resistant iodine gas sustained-release tool can be used almost semi-permanently, there is an advantage that the hydrous soft lens can be disinfected only by the physiological saline and the neutralizing means.

In disinfecting a water-containing soft contact lens, the lens retains a large amount of water and has a property of easily adsorbing and accumulating various chemical substances. Therefore, in the chemical disinfection, the chemical substance contained in the disinfectant solution does not affect the eyes. Safety is extremely important. When the water-resistant iodine gas sustained-release device of the present invention is used, nothing other than iodine gas elutes from the water-resistant iodine gas sustained-release device into the disinfecting liquid as described above, It will be safe. On the other hand, when a polymer compound that absorbs gas and is not covered with a sheet material that does not substantially permeate liquid water and that has adsorbed iodine is used, impurities whose safety has not been confirmed from the plastic to water There is a risk of elution, and high-concentration iodine may elute in water adhering to the plastic, which may be dangerous for general users to handle. There is no such problem when using the water resistant iodine gas sustained release device of the present invention, and it becomes easy to control the iodine concentration by the coating material.

The iodine gas sustained release device of the present invention can be used for various other purposes. For example, it can be used to prevent microbial growth near the drainage port, prevent microbial growth at stagnation sites, and the like.

The water-resistant iodine gas sustained-release device of the present invention is dipped in an aqueous liquid to dissolve iodine gas in the aqueous liquid,
When disinfecting an aqueous liquid and / or an article that coexists with an aqueous liquid, if a compound that forms a complex with iodine is added to the above aqueous liquid, the release of iodine gas from the water resistant iodine gas sustained release device will significantly increase. However, it has been found that the iodine concentration of the aqueous liquid is significantly increased.

Known compounds that form a complex with iodine include polyvinyl alcohol, polyvinylpyrrolidone, starch, dextrin and polyethylene glycol.
It is also known that nonionic surfactants such as polyoxyethylene-polyoxypropylene block copolymer, polyoxyethylene alkyl ether, polyoxyethylene sorbitan fatty acid ester, and polyoxyethylene stearate also form a complex with iodine. In addition, alkali metal salts of iodine such as potassium iodide and sodium iodide are known to form a soluble complex with iodine. Any of these is effective in the present invention, but hydrous soft contact lens When disinfecting medical instruments such as polyvinyl alcohol, polyvinyl alcohol, polyvinylpyrrolidone and the like are particularly preferable from the viewpoint of safety to the living body. .

The concentration of the above compound added to the aqueous liquid is preferably about 0.05 to 5% by weight. If it is less than 0.05% by weight, the effect of promoting the release of iodine gas becomes insufficient,
5% by weight or more is unnecessary. Polyvinyl alcohol,
Polyvinylpyrrolidone, starch, dextrin and the like are particularly preferably 0.5 to 3% by weight, and in the case of a surfactant, 0.1 to 1% by weight is particularly preferable.

The use of a compound which forms a complex with iodine has an advantage that the iodine concentration required for disinfection can be quickly obtained when it is desired to exert an effect in a short time as in disinfection of contact lenses. When a gas-permeable non-porous film is used as a coating material, the amount of iodine gas permeation is small depending on the type of film, and it may take a long time to increase the iodine concentration of the surrounding aqueous liquid. On the other hand, when the iodine gas sustained-release agent is coated with a film having a relatively low iodine gas permeability, the iodine gas released from the iodine gas sustained-release device is small, and therefore it is easy to handle at home. Therefore, when a water-resistant iodine gas sustained-release device using a non-porous film having a relatively low iodine gas permeability as a coating material is immersed in an aqueous liquid containing a compound that forms a complex with iodine, Since the release of iodine gas is promoted, both handling and disinfection effects can be achieved.

When applied to disinfecting contact lenses, etc., when an aqueous liquid containing polyvinylpyrrolidone, polyvinylalcohol, etc. is used, the iodine released from the iodine gas sustained release device forms a complex with polyvinylpyrrolidone, polyvinylalcohol, etc. Although formed, these complexes stabilize iodine and at the same time reduce irritation to the body and increase safety. Therefore, by adding these compounds that form a complex with iodine, it is possible to promote the release of iodine from the iodine gas sustained release device and at the same time enhance the safety of disinfection.

When the iodine gas sustained-release agent coated with the gas-permeable non-porous film is immersed in an aqueous liquid containing a compound capable of forming a complex with iodine, the aqueous liquid forms a complex with iodine in advance. It is possible to use a solution obtained by adding and dissolving a compound having the ability to do so, but it is also possible to add a water-soluble polyvinyl alcohol film to water and dissolve the polyvinyl alcohol at the time of use. As such a water-soluble polyvinyl alcohol film, "Solvlon" manufactured by Aicello Chemical Co., Ltd.
Etc. are preferably used.

[0061]

EXAMPLES In order to clarify the present invention more specifically, some examples will be shown below.

Experimental Example 1 200 g of molding pellets (manufactured by Mitsubishi Rayon Co., Ltd.) of Diapet ABS (variety PS-505) and 260 g of iodine flakes (manufactured by Japan Natural Gas Co., Ltd.) were placed in a polypropylene bottle and sealed. Then, it was heated in an oven at 65 ° C. for 5 hours with occasional shaking to completely adsorb iodine. Then, after heating at 80 ℃ for 12 hours, 105 ℃
And heat treated for 24 hours. From the increase in the weight of the pellet, it was found that 130% by weight of iodine was adsorbed on the pellet based on the weight of ABS. 12 g of each of the pellets was packed in a bag for a tay bag and heat-sealed.

Example 1 Six bags of the ABS resin pellets adsorbing iodine obtained in Experimental Example 1 were placed in a plastic rectangular container of 18 × 12 × 6 cm, and 20 pieces of JK wiper (Clear Co., Ltd.) were placed. It was put in, a lid with packing was attached, and it was sealed with a clip. After leaving it at room temperature for 24 hours, take out the JP wiper.
When a sheet was immersed in 200 ml of water, iodine water having a concentration of 18 ppm was obtained, and it was found that iodine was adsorbed enough for disinfection. Further, even after repeating this operation 30 times, the amount of iodine adsorbed on the JP wiper hardly changed, and it was confirmed that it can be used many times.

Example 2 and Comparative Example 1 The hand sanitizing effect of the iodine-containing article produced by the method of the present invention was examined. First, to check the bacteria on the palm before disinfection,
A disposable petri dish with a diameter of 35 mm and a depth of 10 mm was placed on a tryptic soy agar medium (pearl core “Eiken” lot 1310).
2) was put and pressed against the palms of the four test subjects. Next, as Comparative Example 1, one JP wiper was wet with sterilized ion-exchanged water, and after squeezing, the palms of four test subjects were wiped for 10 seconds, and then the medium was pressed against the palms in the same manner as above. Next, as Example 2, one JP wiper on which iodine was adsorbed in Example 1 was wetted with sterilized ion-exchanged water, and after squeezing, the palms of four test subjects were wiped for 10 seconds, and the medium was placed on the palm in the same manner as above. I pressed it. After culturing each medium at 33 ° C. for 48 hours, the growth state of the bacteria was observed. Regarding the palm before wiping with the wiper and the palm wiped with the iodine-unadsorbed wiper, a large number of colonies of bacteria were observed for all the subjects, but for the palm wiped with the iodine-adsorbed wiper, for any subject Almost all the bacteria had disappeared. This confirmed the excellent disinfecting effect of the iodine-containing article of the present invention.

Example 3 and Comparative Example 2 The disinfection effect of articles using the iodine-containing article produced by the method of the present invention was examined. As a model such as a table having a rough surface, scratches were made on the inner surface of a plastic petri dish with a cutter in a grid pattern of 3.5 cm square at 0.5 cm intervals with a cutter. S. aureus ATCC65
38) A bacterial solution of 5.0 × 10 ⁶ cfu / ml was prepared, and 100 μl of the bacterial solution was added to the petri dish and spread over the whole.
As Comparative Example 2, one piece of JP wiper was wetted with sterilized ion-exchanged water, squeezed, and then the inner surface of the petri dish was wiped for 10 seconds, then 2 ml of the inactivating agent-containing diluent (DPBST solution) was added and the petri dish was vortexed. Of the soybean casein medium (S
The cells were cultured at 33 ° C. for 48 hours using a CDLP medium), and the viable cell count was determined to be 1.1 × 10 ⁵ .
In addition, as Example 3, one JP wiper which adsorbed iodine in Example 1 was wetted with sterilized ion-exchanged water, and after squeezing, the inner surface of the petri dish was wiped for 10 seconds in the same manner as in Comparative Example 2 and the same as Comparative Example 2. When the number of viable cells was measured by treating the above, the number of viable cells was 0. Next, E. coli
ATCC8739) A bacterial solution of 5.2 × 10 ⁶ cfu / ml was prepared and the same test as above was conducted. As for the wiper which did not adsorb iodine, 6.0 × 10 ⁴ cf
u / ml viable bacteria were detected. On the other hand, the number of viable bacteria was 0 for the wiper which adsorbed iodine in Example 2.
From this, it was confirmed that the iodine-containing article of the present invention is effective for disinfecting articles.

Example 4 and Comparative Example 3 A tea bag packaging of the iodine resin-adsorbed ABS resin pellets obtained in Example 1 was filled with GORE-TEX with a pore size of 1 micron.
^{An R} membrane and a polyester fiber non-woven fabric having a two-layer structure (manufactured by Japan Gore-Tex Co., Ltd.) were used for coating. Even if the water-resistant iodine gas sustained-release device coated with GORE-TEX was put into water, water did not enter the inside. Soak this in 100 ml of water and leave it at room temperature.
Updated the water once a day. After 6 months, no intrusion of water was observed inside the coating material, except for a trace amount of water which is considered to be due to diffusion of water vapor. Further, in the initial stage of the experiment, the iodine concentration after soaking in water overnight was 26 ppm, and after 6 months, the iodine concentration after soaking in water overnight was 18 ppm. On the other hand, for the sample which was subjected to the same operation as it was in the tay bag packaging, the iodine concentration in the initial stage of the experiment was 120 ppm, 6
The iodine concentration after 6 months was 6 ppm. Therefore, it was found that iodine can be stably released over a long period of time by using the water resistant iodine sustained release device.

Example 5 10 g of ABS resin pellets adsorbing iodine obtained in Experimental Example 1 were laminated with a polyethylene non-woven fabric to give a thickness 2
It was packed in a bag of 5 micron Espoir film (manufactured by Mitsui Chemicals) and heat-sealed to obtain a water-resistant iodine gas sustained release tool. When this was immersed in 100 ml of tap water, no water entered inside. The iodine concentration in water after immersion for 12 hours at room temperature was 40 ppm. Water was exchanged once a day except on holidays, and the iodine concentration in the water after immersion in tap water overnight after 3 months at room temperature was 31 ppm. After 3 months, a small amount of water entered the inside of the water resistant iodine gas sustained release tool and iodine was dissolved therein, but this iodine water did not leak to the outside.

Example 6 13 g of the ABS resin pellets adsorbing iodine obtained in Experimental Example 1 were packed in a bag of Tyvek 1422A (manufactured by Asahi-Dupon Flash Span Products Co., Ltd.), heat-sealed, and water-resistant iodine gas was gradually removed. It was a free-standing item. When this was immersed in 100 ml of tap water, no water entered inside. The iodine concentration in water after soaking overnight at room temperature is 26
It was ppm. After exchanging water once a day except for holidays and after 3 months at room temperature, the iodine concentration in water after immersion in tap water at room temperature overnight was 21 ppm. After 3 months, a slight amount of water had invaded the iodine gas sustained-release tool, but the iodine water inside did not leak to the outside.

Example 7 13 g of the iodine-adsorbed ABS resin pellet obtained in Experimental Example 1 was used as an OTE film (TP manufactured by Otsuka Techno Co., Ltd.).
(X-polyethylene composite film), and heat-sealed to obtain a water-resistant iodine gas sustained release tool. When this was immersed in 100 ml of tap water, no water entered inside. Iodine concentration in water after soaking overnight at room temperature is 10pp
It was m. Except for holidays, change water once a day for 3 days at room temperature
After a lapse of months, the iodine concentration in the water after immersion in tap water overnight was 9 ppm. Further, after 3 months, no water penetrated into the iodine gas sustained release device.

Example 8 11 g of the iodine gas sustained-release agent obtained in Experimental Example 1 was added to LLV-
It was packed in a bag of MTV film (low density linear polyethylene, manufactured by Nimura Chemical Co., Ltd.) and heat-sealed to obtain a water-resistant iodine gas sustained release tool. When this was immersed in 100 ml of tap water, no water entered inside. 1 at room temperature
The iodine concentration in water after the night immersion was 11 ppm. Except for holidays, change the water once a day, and after 3 months at room temperature, the iodine concentration in the water after soaking in tap water overnight is 10 ppm.
Met. In addition, no water penetrated into the water resistant iodine gas sustained release device.

Example 9 13 g of the ABS resin pellets adsorbing iodine obtained in Experimental Example 1 was used as a POROFRESH film (POLO-F).
It was packed in a bag manufactured by Nimura Chemical Co., Ltd. and heat-sealed to obtain a iodine gas sustained release tool. 100 ml of tap water
When immersed in water, no water penetrated inside. The iodine concentration in water after overnight immersion at room temperature was 10 ppm. Except for holidays, the water is changed once a day, and after 3 months at room temperature, the iodine concentration in the water after immersion in tap water overnight is 9 pp.
It was m. In addition, no water penetrated into the iodine gas sustained release device.

Example 10 The iodine gas sustained-release device obtained in Example 7 was immersed in water for 3 months, and then immersed in 20 ml of an iodine solution having an iodine concentration of 9 ppm, which was immersed in water overnight, and S. aureus.
ATCC 6538) at a concentration of about 1 × 10 ⁶ cfu / ml
And incubate at 23 ° C. for 60 minutes, this solution is appropriately diluted with physiological saline containing 0.5% sodium thiosulfate to prepare a pour plate, which is set at 32 ° C. When the viable cell count was measured by culturing for 48 hours using an incubator, the viable cell count was zero.

Example 11 The iodine gas controlled release tools of Examples 4 to 9 were placed in a shower faucet (internal volume: 50 ml) molded from polypropylene resin by an injection molding method and attached to a sterile water device for hand washing water at 40 ° C. As a result of using 4 liters of warm water for 4 minutes per minute and averaging a total of 60 minutes a day, no faucet contamination was found at all in 3 months.

Example 12 11 g of the ABS resin pellet having the iodine adsorbed therein obtained in Experimental Example 1 was placed in a bag of Tyvek 1460B (manufactured by Asahi-Dupon Flash Span Products Co., Ltd.) and heat-sealed. The six pieces were placed in a plastic rectangular container of 18 × 12 × 6 cm, 20 JP wipers (CLEA Co., Ltd.) were put therein, the lid with packing was sealed, and the pieces were sealed with clips. After standing at room temperature for 24 hours, the JP wiper was colored brown and adsorption of iodine was observed. Similarly, when the above-mentioned JP wiper was wetted with water and squeezed, the JP wiper exhibited a deep purple color due to the iodine-starch reaction, showing that iodine was adsorbed.

Example 13 and Comparative Example 3 Iodine-adsorbed ABS resin pellets 11 g obtained in Experimental Example 1 were placed in a bag of LLV-MTV film similar to that in Example 8 and heat-sealed, and four iodine gases were gradually added. Created a free-standing item. Each of the iodine gas sustained-release tools was treated with 1% by weight of polyvinyl alcohol (saponification degree: 86 to 90%, polymerization degree: 900).
To 1100, Wako Pure Chemical Industries, Ltd., soluble starch 1% by weight (Wako Pure Chemical Industries, Ltd.), potassium iodide 1% by weight (Wako Pure Chemical Industries, Ltd.) or Nikko Chemical (Shares) ) GO460 (tetraoleic acid POE (6
0 mol) sorbit) was immersed in 100 ml of purified water added with 0.5% by weight, and allowed to stand at room temperature for 40 hours.
The iodine concentration in water was 100 ppm or more.
On the other hand, the iodine concentration in water when operating in the same manner as above except that polyvinyl alcohol was not added to purified water was 14
It was ppm.

Example 14 4 g of the iodine resin-adsorbed ABS resin pellet obtained in Experimental Example 1 was placed in a bag of a 30-micron-thick Espoir film (manufactured by Mitsui Chemicals) and heat-sealed to gradually release iodine gas for contact lenses. I made a tool. A contact lens treatment liquid prepared by adding 1.0 w / v% of polyvinyl alcohol to physiological saline was prepared.
0 ml and the iodine gas sustained release tool described above were placed in a container with a glass lid, and the soft 72
Two sheets (manufactured by Menicon Co., Ltd.) were immersed at room temperature. The treatment liquid after 3 hours was colored red and the iodine concentration was 14 ppm. Remove the contact lens from the processing solution and
The iodine was neutralized by rinsing with an aqueous solution containing 5 w / v% sodium thiosulfate. No lens coloring was observed. Even after this cycle was repeated 30 times without updating the iodine gas sustained release agent and only the treatment liquid was repeated, the lens was not colored. During this period, the iodine concentration of the treatment liquid did not decrease as the number of treatments increased.

[0077]

INDUSTRIAL APPLICABILITY According to the present invention, an iodine-containing article such as an iodine-containing fiber sheet material can be safely prepared as shown in Example 1 by using an iodine gas sustained-release agent as an iodine gas generating source. . Its preparation is extremely simple and inexpensive. Further, the iodine gas sustained-release agent as the iodine gas generating source can be used any number of times.

The obtained fibrous sheet material becomes a strong disinfecting sheet only by immersing it in tap water or the like, and can be used for disinfecting fingers, disinfection of articles, etc. as shown in Examples 2 and 3.
This is simpler and more effective than conventional methods. The disinfection system of the present invention can also be used for disinfection of the area around an iodine gas sustained release agent and disinfection of gauze, cloth, and the like.

A water-resistant iodine gas sustained-release tool coated with a sheet-like material which is permeable to gas and substantially impermeable to liquid water is
As shown in Examples 4 to 10 and Example 12, iodine gas is gradually released without being in contact with water even when it is wet with water or in water. Therefore, disinfection in an environment where water is present and in water Can be used for sustained release of iodine gas. This is Example 1
As shown in 1, when used to prevent microbial reverse contamination of a sterile water faucet, the bactericidal effect can be exhibited without direct contact with water, so durability is improved and the iodine concentration released changes with time. Less. Also, when used for disinfecting contact lenses, the lens can be easily disinfected simply by immersing the iodine gas sustained release tool and the contact lens in physiological saline solution, and iodine gas dissolves in physiological saline solution. It is highly safe because there is no risk of water-soluble substances eluting from the iodine gas sustained release device.

Further, as shown in Example 13, when a compound that forms a complex with iodine is added to water in which the iodine gas sustained release device is dipped, the iodine gas release from the iodine gas sustained release device is accelerated and the covering sheet. Even if a film having a relatively low iodine permeability is used as the substance, an iodine concentration effective for disinfection can be obtained in a short time. If this is applied to the disinfection of contact lenses, a safe and simple excellent system can be constructed as shown in the fourteenth embodiment.

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) B01J 20/28 B01J 20/28 A 4L031 C02F 1/50 510 C02F 1/50 510A 4L055 520 520B 520L 531 531L 540 540B 540F C08K 3/16 C08K 3/16 D06M 11/09 D21H 19/30 D21H 19/30 21/20 21/20 C08L 101/00 // C08L 101/00 D06M 11/00 Z F term (reference) 4C058 AA09 BB07 CC09 EE15 EE16 EE24 JJ16 JJ29 4F073 AA09 AA24 AA32 BA02 BA03 BA06 BA07 BA11 BA13 BA17 BA18 BA20 BA27 BA29 BB04 DA02 EA01 EA56 GA11 4G066 AA31B AC12C AC17C02 DA01 BB01 DA01 BB01 DA01 BB01 DA01 A02 CAT01 DA03 DA01 A01 CAT4 DA01 DA01 A02 CAT4 DH06 DH10 4J002 AB011 AB021 AB041 AB051 BB221 BC061 BE 021 BE031 BG101 BJ001 BN151 CF001 CH021 CL001 DD006 FB261 GB01 4L031 BA07 DA00 DA09 DA19 4L055 AG01 AG87 AG99 AH17 AH21 AH50 GA27

Claims (23)

[Claims] 1. A method for producing an iodine-containing article, which comprises causing a iodine-adsorptive article to adsorb iodine by using a polymer compound having adsorbed iodine as an iodine gas generation source. 2. An ABS resin, an AS resin, an ethylene / vinyl alcohol copolymer, a polyamide, a polyacrylonitrile, in which a polymer compound adsorbing iodine adsorbs iodine.
The method for producing an iodine-containing article according to claim 1, which is selected from the group consisting of polyacrylonitrile / vinyl chloride copolymer, polyvinyl alcohol, and formalized polyvinyl alcohol. 3. The polymer compound having adsorbed iodine is beads,
The method for producing an iodine-containing article according to claim 1 or 2, which is in the form of powder, fiber, film, woven fabric, non-woven fabric or gel. 4. The iodine-containing article according to claim 1, wherein a polymer compound having adsorbed iodine is placed in a closed container having an openable / closable lid, and an iodine-adsorptive article is allowed to coexist in the closed container. Production method. 5. An iodine-containing article obtained by using a polymer compound that has adsorbed iodine as an iodine gas generation source and allowing this to coexist with an iodine-adsorptive article. 6. The iodine-containing article according to claim 5, wherein the iodine-adsorptive article is a fibrous sheet. 7. The fiber sheet material is treated with a polyamide epichlorohydrin resin or a polyamine / polyamide polyamide epichlorohydrin resin.
The iodine-containing article as described. 8. The iodine-containing article according to claim 6, wherein the fibrous sheet material is a paper or non-woven fabric using a polyamide epichlorohydrin resin or a polyamine / polyamide polyamide epichlorohydrin resin as a paper strengthening agent. 9. A disinfection method, which comprises using an iodine-containing fibrous sheet obtained by allowing a polymer compound having adsorbed iodine and an iodine-adsorbing fibrous sheet to coexist and moistening with water. 10. A water-resistant iodine gas sustained-release device, characterized in that a polymeric compound having adsorbed iodine is coated with a sheet-like material which is permeable to gas and substantially impermeable to liquid water. 11. A sheet-like material which is permeable to gas and substantially impermeable to liquid water is selected from the group consisting of a hydrophobic porous membrane, a water-impermeable hydrophobic nonwoven fabric and a gas-permeable non-porous film. The water resistant iodine gas sustained release device according to claim 10, which is selected. 12. The water-resistant iodine gas sustained release device according to claim 11, wherein the hydrophobic porous film is a polytetrafluoroethylene-based film or a polyolefin-based film. 13. The pore diameter of the polytetrafluoroethylene-based hydrophobic porous membrane is 1.5 μm or less.
2. The iodine gas sustained release device as described in 2. 14. A water-impermeable hydrophobic nonwoven fabric is formed by randomly entangling polyethylene ultrafine fibers having a diameter of 0.5 to 10 microns to form a sheet, and the fibers are partially fused by heat. The water resistant iodine gas sustained release device according to claim 11, which is a non-woven fabric. 15. The iodine gas sustained release device according to claim 11, wherein the gas-permeable non-porous film is a polyolefin film. 16. The polyolefin-based film selected from the group consisting of a low-density polyethylene-based film, a gas-permeable polypropylene-based film, a poly-4methylpentene-1 film, and an ethylene / vinyl acetate copolymer film. The iodine gas sustained-release device according to claim 15, which is 17. A water-resistant iodine gas sustained-release device in which a polymer compound having adsorbed iodine is coated with a sheet-like material that is permeable to gas and substantially impermeable to liquid water, and is discharged from the surroundings by iodine gas. A disinfection system characterized by disinfecting the atmosphere and / or liquid and the articles present in the atmosphere and / or liquid. 18. The disinfection system according to claim 17, wherein the container existing in the liquid is a contact lens. 19. A microbial reverse contamination of a liquid faucet, characterized in that an iodine gas sustained-release tool coated with a sheet-like material permeable to gas and substantially impermeable to liquid water is inserted into the liquid faucet. Prevention method. 20. A capability of forming a complex with iodine by a water-resistant iodine gas sustained-release device obtained by coating a polymer compound having adsorbed iodine with a sheet-like material which is permeable to gas and substantially impermeable to liquid water. A disinfecting method, which comprises immersing a compound having the above-mentioned in an aqueous liquid in which the compound is dissolved to allow a substance to be disinfected to coexist in the aqueous liquid. 21. The compound having the ability to form a complex with iodine is selected from polyvinyl alcohol, polyvinylpyrrolidone, starch, dextrin, polyoxyethylene, a nonionic surfactant having a polyoxyethylene chain and an alkali metal salt of iodine. The disinfection method according to claim 20, which is selected from the group consisting of: 22. The disinfecting method according to claim 20, wherein the water-soluble polyvinyl alcohol film is dissolved in an aqueous liquid. 23. The disinfecting method according to claim 20, wherein the object to be disinfected is a contact lens.