JP2003113025A - Cosmetic and composition for skin - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic having excellent sense of use such as filmy feeling, body feeling, etc., desirable properties and excellent stability, a composition for the skin and a raw material compound thereof. SOLUTION: This raw material compound for a cosmetic and a composition for the skin is a polyglyceryl isostearate represented by chemical formula (I) [1-12 substituent groups among Rs are each chemical formula (II) and the residual Rs are each H; n is an integer of 0-8]. This cosmetic or composition for the skin comprises the raw material compound. The raw material compound has preferably 5,000-35,000 mPa.s viscosity at 25 deg.C.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a raw material compound useful in make-up, skin care and hair care products, which are desired to bring about an excellent feeling of use when applied to skin, hair and the like, and a cosmetic containing the same. And dermatological compositions. More specifically, the present invention relates to a raw material compound which is useful in cosmetics and dermatological compositions having excellent feelings of use such as film feeling and body feeling and maintaining desirable physical properties.

[0002]

2. Description of the Related Art Conventionally, hydrocarbon-based liquid oils such as wax and heavy liquid paraffin have been used in order to improve the feeling of use of cosmetics, skin compositions and the like, particularly the feeling of film and the feeling of body. It was For example, Japanese Patent Application Laid-Open No. 2001-158718 discloses a lipstick composition containing a predetermined amount of a polyethylene wax having an average molecular weight of 300 to 700 and a liquid oil component having one or more hydroxyl groups in the structure. It is described that a product excellent in sex, spreadability, luster and makeup lasting can be obtained. However, even if these raw materials are blended, it has not been possible to obtain a sufficiently satisfactory feeling of use such as a desired film feeling and a feeling of body.

It has also been reported that the use of polar oils such as fatty acid esters can enhance the variation in use feeling and satisfaction. For example, Japanese Patent Laid-Open No. 10-13
9628 discloses a boron nitride powder and a foundation containing diglyceryl diisostearate and / or diglyceryl triisostearate in a binder,
It has been shown that cosmetics such as eye shadow have excellent adhesiveness, spread thinly and have a transparent feeling. Further, in JP-A-2000-302623, polyglyceryl diisostearate, carboxyvinyl polymer and / or
Alternatively, an oily cosmetic containing an alkyl-modified carboxyvinyl polymer is disclosed, and it is said that a product having good spread and spread, capable of being uniformly applied, and easy to remake is obtained. Japanese Unexamined Patent Publication No. 2000-319219 discloses a homogeneous, highly stable and agglomerate containing an ester of a fatty acid or an alcohol having a saturated or branched carbon chain having 24 to 28 carbon atoms and a silicone compound. A cosmetic composition rich in properties is disclosed. In addition, a saturated hydrocarbon having a side chain and a predetermined melting point, and an oily solid cosmetic containing diglyceryl diisostearate and / or diglyceryl triisostearate have excellent shape retention and spread easily during application. It has also been shown to have good smoothness and an excellent feeling of use (Japanese Patent No. 2821693).

[0004]

The isostearoyl group in the above polyglyceryl isostearate is IUP.
An isostearoyl group according to the AC nomenclature, ie 1
Not limited to the 6-methylheptadecanoyl group, it is an acyl group having a carbon number of 18 and having a branched structure at various sites. Therefore, the structure of polyglyceryl isostearate is diversified. Commercial products that are specifically mentioned as such conventional polyglyceryl isostearate include NIKKOL DGDIS (manufactured by Nikko Chemicals), which is diglyceryl diisostearate, Emalex DISG-2 (manufactured by Nippon Emulsion Co., Ltd.), Matsunate DI (Matsumoto Pharmaceutical Co., Ltd.). ), Unigri GI-202 (manufactured by NOF Corporation), Cosmol 42 (manufactured by Nisshin Oil Co., Ltd.), Triglyceryl diisostearate Emalex DISG-3 (manufactured by Nippon Emulsion), Unigri GI-203 (manufactured by NOF Corporation) ), And NIKKOL which is decaglyceryl diisostearate
Decaglyn2-IS (manufactured by Nikko Chemicals),
Emalex DISG-10 (manufactured by Nippon Emulsion Co., Ltd.) and the like. Although these can improve the feeling of use to some extent when incorporated into a cosmetic, it is difficult to properly maintain physical properties such as viscosity and hardness, and a satisfactory cosmetic or dermatological composition is provided. I couldn't do that.

Therefore, the present invention is useful as a raw material for make-up, skin care and hair care products, and skin compositions, which can provide an excellent feeling of use such as a filmy feeling and a rich feeling when applied to skin, hair and the like. It is an object of the present invention to provide a useful compound which does not impair the physical properties desired for cosmetics and the like after compounding, the high temperature stability of oily solid cosmetics and the like.

[0006]

In view of the above situation, the present inventors have conducted diligent research and as a result, found that a polyglycerin ester containing a specific isostearoyl group as a fatty acid composition has a very high viscosity. By blending the heading, such polyglyceryl isostearate,
The present invention has been completed by clarifying that it is possible to prepare a cosmetic or dermatological composition that has a good feeling in use and that retains preferable physical properties.

That is, the present invention has the following chemical formula (I):

[0008]

[Chemical 3]

[In the formula, the substituents 1 to 12 in R are represented by the following chemical formula (II):

[0010]

[Chemical 4]

Represents a 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group represented by the following, the rest R represents H, and n represents an integer of 0 to 8].
And a raw material compound for a cosmetic or dermatological composition, which is polyglyceryl isostearate.

The present invention further provides a cosmetic and dermatological composition characterized by containing at least one of the above-mentioned raw material compounds. Suitable cosmetics include emulsions and creams. , Sunscreen agents, lipstick compositions or powder cosmetics are included, and lipstick compositions such as lipsticks and lip glosses are particularly preferable.

[0013]

BEST MODE FOR CARRYING OUT THE INVENTION The following chemical formula (I), which is a raw material compound for cosmetics and dermatological compositions of the present invention:

[0014]

[Chemical 5]

[Wherein the substituents 1 to 12 of R are the following chemical formula (II):

[0016]

[Chemical 6]

A 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group represented by the following, the rest R represents H, and n represents an integer of 0 to 8].
In polyglyceryl isostearate represented by,
Those in which 1 to 4 Rs, preferably 3 Rs, are substituents represented by the chemical formula (II) are preferable as raw material compounds capable of imparting a favorable usability to cosmetics and dermatological compositions. However, the viscosity and hardness of the cosmetics are appropriately maintained, and the high temperature stability is not impaired.

In the above chemical formula (II), n is 0 to
8, more preferably 0 to 2, and n is 0, that is, mono- or poly- [2-
(1,3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is preferred. When n is 9 or more, the molecular weight becomes too large, which causes undesired feeling of use such as stickiness in the blended cosmetics, which is not preferable.

The compound of the present invention is specifically tri [2- (1,3,3-trimethyl) butyl-5,7,7.
-Trimethyloctanoic acid] diglyceryl, di [2-
(1,3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl, tetra [2- (1,
3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl and di [2- (1,3,3-)
Trimethyl) butyl-5,7,7-trimethyloctanoic acid] triglyceryl, tri [2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] triglyceryl, tetra [2- ( Examples include 1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] triglyceryl, particularly tri [2- (1,3,3-).
Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is preferable in that it can bring more excellent film feeling and rich feeling to cosmetics but does not impair physical properties.

As described above, these compounds have higher viscosities than conventional products, but the viscosities at 25 ° C. are especially 5000 to 35000 mPa · s, more preferably 15.
000-30000 mPa · s, most preferably about 22
Those having a viscosity of 000 mPa · s are suitable for use as a raw material compound for cosmetics, which can impart an excellent film feeling and richness and do not cause undesirable changes in physical properties such as a decrease in viscosity and a decrease in hardness. It Further, when the raw material compound of the present invention is added, a composition having little change with time in physical properties such as viscosity and hardness can be obtained, so that it is suitable for topical application even after long-term storage, and forms a desirable film at the application site. A skin composition capable of exerting a medicinal effect can be prepared.

The method for producing polyglyceryl isostearate is based on the generally known method for producing polyglyceryl isostearate. That is, glycerol is dehydrated and condensed at about 250 ° C. in the presence of a base such as sodium hydroxide to prepare polyglycerol having an appropriate degree of polymerization. Then, in the presence of a suitable catalyst such as an alkali catalyst, 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid is added to carry out the esterification reaction.

The cosmetics to which the above-mentioned raw material compounds can be blended are not particularly limited, and include skin cosmetics such as lotions, milky lotions, cleansing creams, nutritional creams, lip balms, hand creams and sunscreens, and makeup base creams. , Lipstick compositions such as liquid and powder foundation, eye color, cheek color, lipstick, lip gloss, make-up cosmetics such as eyebrow and control color, hair cosmetics such as hair cream and hair treatment, body lotion, Body cosmetics such as body creams and leg creams can be mentioned, but it is desirable that they are excellent in film feeling and rich feeling that give a rich feeling of use, emulsions, creams, sunscreens, lipstick compositions or powder cosmetics. , Especially lipstick, It preferred in lipstick compositions such gloss.

The amount of the raw material compound of the present invention blended in the cosmetics and dermatological compositions may vary depending on the desired properties of the cosmetics and dermatological compositions and the degree of feel to be imparted. , 3 to 10% by weight for liquid products such as emulsions, 3 to 25% by weight for creams, 0.5 to 15% by weight for powder cosmetics, and oil-based cosmetics such as lipstick compositions. In the case of (1), it is preferable to add 0.1 to 60% by weight from the viewpoint of giving a film feeling, a rich feeling, etc. and a rich feeling of use.

Two or more kinds of such raw material compounds differ in the degree of polymerization of polyglycerol and / or the content of 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group. You may mix and mix.

The cosmetics of the present invention will be outlined below.

First, in addition to the above-mentioned raw material compounds, various components generally used in cosmetics can be added to the emulsified composition such as emulsion and cream, if necessary. Examples of these components include oily components, surfactants, moisturizers, higher alcohols, sequestering agents, thickeners or dispersion stabilizers, gelling agents for oily components, ultraviolet absorbers, blood circulation promoters, various extractions. Liquids, inorganic and organic pigments, clay minerals and organic modified products thereof, inorganic and organic pigments whose surface is modified with metal soap or silicone, colorants such as organic dyes, preservatives, antioxidants, pigments, thickeners. Agents, pH adjusters, fragrances, cooling agents, antiperspirants, bactericides, skin activating agents and the like.

As the oily component, fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, esters, essential oils, silicone oils, more specifically, avocado oil, camellia oil, turtle oil, macadamia nuts Oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil,
Castor oil, linseed oil, safflower oil, evening primrose oil, cottonseed oil, eno oil, soybean oil, peanut oil, teaseed oil, kaya oil, rice bran oil, cinnamon oil, Japanese tung oil, jojoba oil, germ oil,
Triglycerin, glyceryl trioctanoate, glyceryl triisopalmitate, cocoa butter, coconut oil, horse fat, hardened coconut oil, palm oil, beef tallow, sheep fat, hardened beef tallow, palm kernel oil, lard, beef bone fat, mokuro kernel Oil, hydrogenated oil, beef tallow, mokuro, hydrogenated castor oil, beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, ivorot,
Whale wax, montan wax, nuka wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax,
Lanolin fatty acid isopropyl, hexyl laurate, reduced lanolin, hard lanolin, shellac wax, polyoxyethylene lanolin alcohol ether, polyoxyethylene lanolin alcohol acetate, polyoxyethylene cholesterol ether, lanolin fatty acid polyethylene glycol, polyoxyethylene hydrogenated lanolin alcohol ether, Liquid paraffin, ozokerite, squalene, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, silicone oil and the like can be mentioned.

Among the surfactants, lipophilic nonionic surfactants include, for example, sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquiole. Sorbate, sorbitan trioleate, penta-2-ethylhexylate diglycerol sorbitan, tetra-2-ethylhexylate diglycerol sorbitan, and other sorbitan fatty acid esters, monocottonseed oil fatty acid glycerin, monoerucate glycerin, sesquioleate glycerin, monostearate glycerin , Α, α'-glycerin fatty acids such as glycerin pyroglutamate oleate, propylene glycol fatty acid esters such as propylene glycol monostearate, hardened castor Oil derivatives, glycerin alkyl ethers and the like. Examples of the hydrophilic nonionic surfactant include polyoxyethylene sorbitan fatty acid esters, polyoxyethylene sorbit fatty acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene alkyl ethers, Polyoxyethylene alkyl phenyl ethers, polyoxyethylene polyoxypropylene block polymers, polyoxyethylene polyoxypropylene alkyl ethers, tetrapolyoxyethylene / tetrapolyoxypropylene ethylenediamine condensates, polyoxyethylene castor oil derivatives , Polyoxyethylene hydrogenated castor oil derivative, polyoxyethylene beeswax lanolin derivative, alkanolamides, polyoxyethylene propylene glycol Le fatty acid esters, polyoxyethylene alkyl amines,
Examples thereof include polyoxyethylene fatty acid amides, sucrose fatty acid esters, polyoxyethylene nonylphenylformaldehyde condensates, alkylethoxydimethylamine oxides, trioleylphosphoric acids and the like. Examples of the anionic surfactant include fatty acid soap, higher alkyl sulfate ester salts, alkyl ether sulfate ester salts, N-acyl sarcosinic acids, higher fatty acid amide sulfonates, phosphate ester salts, sulfosuccinates, alkylbenzene sulfonates. , Higher fatty acid ester sulfate ester salts, sulfated oil, polyoxyethylene alkyl ether carboxylic acids, polyoxyethylene alkyl allyl ether carboxylate salts, α-olefin sulfonates, higher fatty acid ester sulfonate salts, secondary alcohol sulfate ester salts , Higher fatty acid alkylolamide sulfate, sodium lauroyl monoethanolamide succinate, ditriethanolamine N-palmitoyl aspartate, sodium caseinate, etc. It is. Examples of the cationic surfactant include alkyl trimethyl ammonium salts, alkyl pyridinium salts, alkyl quaternary ammonium salts, alkyl dimethyl benzyl ammonium salts, alkyl isoquinolinium salts, dialkyl molyphonium salts, alkyl amine salts, alcohol fatty acid derivatives. , Benzalkonium chloride, benzethonium chloride and the like. Examples of the amphoteric surfactant include imidazoline-based amphoteric surfactants and betaine-based surfactants.

Examples of moisturizers include polyethylene glycol, propylene glycol, glycerin, 1,3-
Butylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, caronic acid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, bile salt, dl-pyrrolidone carboxylate, short chain soluble collagen , Diglycerin (ethylene oxide)
Examples include propylene oxide adducts and extracts from other natural organisms.

Examples of higher alcohols include straight chain alcohols such as lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol and cetostearyl alcohol, monostearyl glycerin ether (butyl alcohol), 2-decyltetradecyl alcohol. Examples thereof include branched chain alcohols such as knoll, lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, and octyldodecanol.

Examples of the sequestering agent include 1-hydroxyethane-1,1-diphosphonic acid, 1-hydroxyethane-1,1-diphosphonic acid tetrasodium salt,
Disodium edetate, trisodium edetate, tetrasodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid,
Examples thereof include citric acid, ascorbic acid, succinic acid, and edetic acid.

Water-soluble polymers useful as thickeners or dispersion stabilizers include araavia gum, tragacanth gum,
Plant-based macromolecules such as galactan, guar gum, carob gum, karaya gum, carrageenan, pectin, agar, starch, glycyrrhizinic acid, microbial macromolecules such as xanthan gum, dextran, succinoglucan, and vullan, collagen, casein, albumin, gelatin, etc. Natural water-soluble polymers including animal-based polymers; semi-synthetic water-soluble polymers such as starch-based polymers, cellulose-based polymers, alginic acid-based polymers; vinyl-based polymers, polyoxyethylene-based polymers, polyoxy Synthetic water-soluble polymer such as ethylene polyoxypropylene copolymer copolymer, acrylic polymer, polyethyleneimine, cationic polymer;
Examples include inorganic water-soluble polymers such as bentonite, magnesium aluminum silicate, laponite, hectorite, and anhydrous silicic acid.

Examples of the gelling agent for the oily component include, but are not limited to, dextrin fatty acid ester, glycerin fatty acid ester and metal soap.
Examples of the dextrin fatty acid ester include dextrin myristate [trade name "Leopearl MKL" manufactured by Chiba Milling Co., Ltd.], dextrin palmitate [trade names "Reopearl KL", "Reopearl TL" manufactured by Chiba Milling Co., Ltd.]. , (Palmitic acid / 2-ethylhexanoic acid) dextrin [trade name "Reopearl TT",
Chiba Flour Milling Co., Ltd.] and the like. Examples of the glycerin fatty acid ester include glyceryl behenate, glyceryl octastearate, glyceryl eicoate, and the like, and one or more of them may be used in combination. Specifically, a trade name “TAISET 26” (manufactured by Taiyo Kagaku Co., Ltd.) containing 20% glyceryl behenate, 20% glyceryl octastearate and 60% hydrogenated palm oil,
A trade name “TAISET 50” (manufactured by Taiyo Kagaku Co., Ltd.) containing 50% glyceryl behenate and 50% glyceryl octastearate can be mentioned. Examples of the metal soap include salts of saturated or unsaturated fatty acids having 10 to 26 carbon atoms and a divalent or higher metal, such as aluminum stearate, aluminum palmitate, aluminum myristate, aluminum laurate, magnesium stearate, and palmitic acid. Ultraviolet absorbers such as magnesium, magnesium myristate, magnesium laurate, zinc stearate, zinc palmitate, zinc myristate, zinc laurate, calcium stearate, calcium palmitate, calcium myristate, calcium laurate, etc., include benzoic acid. Acid UV absorbers, anthranilic acid UV absorbers, salicylic acid UV absorbers; cinnamic acid UV absorbers, benzophenone UV absorbers, triazole UV absorbers, etc.

Examples of the blood circulation promoter include nonyl acid warenylamide, nicotinic acid benzyl ester, nicotinic acid β-butoxyethyl ester, capsaicin, zingerone, cantharitin tincture, ictamol, caffeine, tannic acid, α-borneol, nicotinic acid tocopherol, Examples include inositol hexanicotinate, cyclanderate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthin, γ-oryzanol and the like.

As other drug components, ascorbic acid,
Examples include vitamins such as pyridoxine hydrochloride, various hormones, amino acids, anti-inflammatory agents such as lysozyme chloride, whitening agents such as sulfur, astringents, and cooling agents.

Various extracts are extracted from natural products and have been shown to bring beneficial effects upon application. Dokudami extract, oyster extract, licorice extract, peony extract, loofah extract, yukinoshita extract, fennel extract, primrose extract. Extract, rose extract, dioxin extract, lemon extract, shikon extract, aloe extract,
Ginger root extract, eucalyptus extract, horse mackerel extract, sage extract, thyme extract, tea extract, seaweed extract, cucumber extract, clove extract, raspberry extract, melissa extract, carrot extract, horse chestnut extract, peach extract, peach leaf extract, mulberry extract, clam extract. Examples include extracts, hamamelis extract, placenta extract, thymus extract, silk extract, licorice extract and the like.

Next, compact type or stick type foundation, eye color, cheek color,
As components of powder cosmetics that can be provided as deodorant sticks, antiperspirant sticks, etc., in addition to the above oily components and cosmetic compounding ingredients, inorganic powders as powder ingredients,
Bright powders, organic powders, pigment powders, composite powders,
And the like, such as spherical, plate-like and needle-like shapes, haze-like particles, fine particles, particle size such as pigment grade, and particle structure such as porous and non-porous are appropriately used.

Specifically, titanium oxide, black titanium oxide,
Conger, ultramarine, red iron oxide, yellow iron oxide, black iron oxide, zinc oxide, aluminum oxide, silicon dioxide, magnesium oxide, zirconium oxide, magnesium carbonate, calcium carbonate, chromium oxide, chromium hydroxide, carbon black, aluminum silicate, silica Magnesium acid salt, magnesium aluminum silicate, mica, synthetic mica, synthetic sericite, sericite, talc, kaolin, silicon carbide, barium sulfate, bentonite, smectite, inorganic powders such as boron nitride, bismuth oxychloride, titanium mica, Iron oxide coated mica, iron oxide mica titanium, tar dye, organic pigment treated mica titanium, bright powders such as aluminum powder, nylon powder, polymethylmethacrylate, acrylonitrile-methacrylic acid copolymer powder, vinyl chloride Down - methacrylic acid copolymer powder, polystyrene powder, polymethylsilsesquioxane powder, wool powder, silk powder,
Crystalline cellulose, organic powders such as N-acyl lysine, fine particles titanium oxide-coated titanium mica, fine particles zinc oxide-coated titanium mica, barium sulfate-coated titanium mica, titanium oxide-containing silicon dioxide, zinc oxide-containing silicon dioxide, and other composite powders, etc. Is mentioned. Further, these powders are blended by surface treatment by a generally known method such as silicones, fluorine compounds, metal soaps, oils, etc. for the purpose of improving the durability of makeup, improving the adhesion to the skin, adjusting the feel and the like. You may.

Oily cosmetics such as lipstick compositions are solid,
It can be provided as a semi-solid form, a liquid form, or a W / O emulsion, and in addition to the raw material compound of the present invention, the above-mentioned oils and fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, and esters. It is possible to use, as a base, an oily component such as a salt, a surfactant, an essential oil or a silicone oil, which is appropriately blended. Furthermore, for the purpose of improving the make-up effect and touch, the above powders, polyhydric alcohols, sugars, sugar derivatives,
Amino acids, amino acid derivatives, moisturizing agents such as salts, benzoic acid, preservatives, antioxidants, ultraviolet absorbers, skin-refining ingredients, cooling agents, and fragrances can be added.

The cosmetics of the present invention outlined above are those in which the blending amounts of various components are determined based on the common general technical knowledge in the technical field, and can be produced by a generally known method.

The dermatological composition of the present invention can be provided in the form of lotions, emulsions, creams, ointments and the like according to cosmetics.
For example, analgesics, antipruritics, astringents, antiphlogistics; germicides / disinfectants; wound protectors; purulent disease agents; emollients containing corrosive agents; And so on. The amounts of the components to be mixed, the manufacturing method and the like are appropriately selected based on the common general technical knowledge in the technical field.

[0042]

The present invention will be described in more detail with reference to examples, but the present invention is not limited thereto. All blending amounts are expressed in weight percent.

Example 1: Emulsion Oil phase composition: (1) stearic acid 2.0, (2) cetyl alcohol 1.5, (3) decamethylpentacyclosiloxane 3.0, (4) dimethyl poly. Siloxane (6c
s) 5.0, (5) polyglyceryl isostearate (viscosity at 25 ° C .: 22000 mPa · s) 3.0,
(6) Vaseline 0.5, (7) Polyoxyethylene monooleate 2.0 Water phase composition: (8) Carboxyvinyl polymer 0.2,
(9) 1,3-butylene glycol 5.0, (10) glycerin 3.0, (11) potassium hydroxide 1.0, (1
2) Methylparaben, a proper amount, (13) ion-exchanged water, the rest (production method) of the aqueous phase parts (8) to (13) are mixed at 70 ° C.,
What mixed and melt | dissolved oil phase parts (1)-(7) was added to this, and emulsification was performed, and the cooling process was carried out and the emulsion was obtained. The polyglyceryl isostearate contains tri [2-
(1,3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl was used. This compound was produced by adding 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid (manufactured by Nissan Chemical Industries, Ltd.) to diglycerin to carry out an esterification reaction. Yes, viscosity at 25 ° C is 22000 mP
It was a.s.

Comparative Example 1: Emulsion Oil phase composition: (1) stearic acid 2.0, (2) cetyl alcohol 1.5, (3) decamethylpentacyclosiloxane 3.0, (4) dimethyl poly. Siloxane 6cs
5.0, (5) polyglyceryl polyisostearate (manufactured by Nisshin Oil Co., Ltd., Cosmol 43; viscosity at 25 ° C .: 250 mPa · s) 3.0, (6) vaseline 0.
5, (7) polyoxyethylene monooleate 2.0 aqueous phase composition: (8) carboxyvinyl polymer 0.2,
(9) 1,3-butylene glycol 5.0, (10) glycerin 3.0, (11) potassium hydroxide 1.0, (1
2) Methylparaben in appropriate amount, (13) Ion-exchanged water, balance (manufacturing method) As in Example 1.

Example 2: Cream Oil phase composition: (1) octamethyltetracyclosiloxane 3.0, (2) methylphenylpolysiloxane 3.
0, (3) Polyglyceryl isostearate (Example 1
5.0), (4) stearic acid 2.0, (5) cetyl alcohol 1.5, (6) stearyl alcohol 0.5, (7) white petrolatum 1.0, (8) tri-2-ethylhexanoic acid. Glyceryl 3.0, (9) cetyl octanoate 3.0, (10) glyceryl monostearate 3.
0, (11) polyoxyethylene sorbitan monostearate 1.0, (12) ethyl paraben 0.
2. (13) Butylparaben 0.1, (14) Perfume Amount of water phase composition: (15) Smecton SA (Kunimine Industries Co. synthetic clay mineral) 1.0, (16) 1,3-butylene glycol 10. 0, (17) glycerin 5.0, (1
8) potassium hydroxide 1.0, (19) magnesium ascorbyl phosphate 0.02, (20) sodium hyaluronate 0.05, (21) ion-exchanged water balance (production method) aqueous phase part (15) to ( 18), (20) and (21) are mixed at 70 ° C., and the oil phase parts (1) to (1) are added thereto.
4) was mixed and dissolved, and emulsified. Then, when the emulsion is cooled to about 40 ° C,
A solution obtained by dissolving (19) in a small amount of (21) was added, followed by stirring and mixing, and further cooling to obtain an emulsion.

Comparative Example 2: Cream Oil phase composition: (1) octamethyltetracyclosiloxane 3.0, (2) methylphenylpolysiloxane 3.
0, (3) polyglyceryl polyisostearate (the same as in Comparative Example 1) 5.0, (4) stearic acid 2.0,
(5) Cetyl alcohol 1.5, (6) Stearyl alcohol 0.5, (7) White petrolatum 1.0, (8) Glyceryl tri-2-ethylhexanoate 3.0, (9) Cetyl octanoate 3.0 , (10) glyceryl monostearate 3.0, (11) polyoxyethylene sorbitan monostearate 1.0, (12) ethyl paraben 0.2, (13) butyl paraben 0.1, (14) perfume suitable amount Aqueous phase composition: (15) Smecton SA, (synthetic clay mineral manufactured by Kunimine Industry Co., Ltd.) 1.0, (16) 1,3-butylene glycol 10.0, (17) glycerin 5.0, (1
8) Potassium hydroxide 1.0, (19) magnesium ascorbate phosphate 0.02, (20) sodium hyaluronate 0.05, (21) ion-exchanged water balance (manufacturing method) According to Example 2.

[Example 3: Sunscreen] Oil phase composition: (1) Dimethyl polysiloxane 5.0,
(2) Methylphenylpolysiloxane 5.0, (3) Polyglyceryl isostearate (same as in Example 1) 1
0.0, (4) (alkyl acrylate / dimethicone) copolymer 1.0, (5) stearic acid 1.0, (6) palmitic acid 1.0, (7) cetyl alcohol 1.5,
(8) White petrolatum 1.0, (9) 4-tert-butyl-4′-methoxydibenzoylmethane 2.0, (1
0) octyl methoxycinnamate 5.0, (11) glyceryl monostearate 3.0, (12) polyoxyethylene sorbitan monostearate 1.0,
(13) Ethylparaben 0.2, (14) Butylparaben 0.1, (15) Perfume Amount of water phase composition: (16) Carboxyvinyl polymer 0.1
5, (17) 1,3-butylene glycol 5.0, (1
8) Potassium hydroxide 1.0, (19) Ion-exchanged water Remaining (Production method) As in Example 2.

[Comparative Example 3: Sunscreen] Oil phase composition: (1) Dimethylpolysiloxane 5.0,
(2) Methylphenyl polysiloxane 5.0, (3) Polyglyceryl polyisostearate (same as Comparative Example 1)
10.0, (4) (alkyl acrylate / dimethicone)
Copolymer 1.0, (5) Stearic acid 1.0, (6)
Palmitic acid 1.0, (7) cetyl alcohol 1.5,
(8) White petrolatum 1.0, (9) 4-tert-butyl-4′-methoxydibenzoylmethane 2.0, (1
0) octyl methoxycinnamate 5.0, (11) glyceryl monostearate 3.0, (12) polyoxyethylene sorbitan monostearate 1.0,
(13) Ethylparaben 0.2, (14) Butylparaben 0.1, (15) Perfume Amount of water phase composition: (16) Carboxyvinyl polymer 0.1
5, (17) 1,3-butylene glycol 5.0, (1
8) Potassium hydroxide 1.0, (19) Ion-exchanged water Remaining (Production method) As in Example 2.

Example 4: W / O Cream Oil phase composition: (1) Dimethyl polysiloxane 10.0,
(2) Methylphenyl polysiloxane 5.0, (3) Polyglyceryl isostearate (same as in Example 1) 5.
0, (4) (alkyl acrylate / dimethicone) copolymer 5.0, (5) polyoxyethylene-modified organopolysiloxane 3.0, (6) octyl methoxycinnamate 5.0, (7) perfume proper amount water phase part Composition: (8) Smecton SA (synthetic clay mineral manufactured by Kunimine Industries Co., Ltd.) 3.0, (9) 1,3-butylene glycol 5.0, (10) glycerin 5.0, (11) L-
Sodium glutamate 2.0, (12) ion-exchanged water The balance (production method) The oil phase parts (1) to (6) were mixed at 70 ° C, and the aqueous phase parts (8) to (12) were heated to 70 ° C. What was mixed and dissolved was added and emulsified. Then, at the stage where the emulsion was cooled to about 40 ° C., after adding (7),
Stir-mixing and further cooling gave W / O cream.

[Comparative Example 4: W / O cream] Oil phase composition: (1) Dimethyl polysiloxane 10.0,
(2) Methylphenyl polysiloxane 5.0, (3) Polyglyceryl isostearate (same as Comparative Example 1)
0, (4) (alkyl acrylate / dimethicone) copolymer 5.0, (5) polyoxyethylene-modified organopolysiloxane 3.0, (6) octyl methoxycinnamate 5.0, (7) perfume proper amount water phase part Composition: (8) Smecton SA (synthetic clay mineral manufactured by Kunimine Industries Co., Ltd.) 3.0, (9) 1,3-butylene glycol 5.0, (10) glycerin 5.0, (11) L-
Sodium glutamate 2.0, (12) ion-exchanged water balance (manufacturing method) According to Example 4.

[Example 5: Lipstick] (1) Polyglyceryl isostearate (same as in Example 1) 60.0, (2) Diisostearyl malate 7.
5, (3) beeswax 15.0, (4) carnauba wax 4.0, (5) lanolin 3.0, (6) legal dye / pigment 10.0, (7) perfume / antioxidant, proper amount (production method ) After heating, melting and mixing the components (1) to (5), the component (6) was added and well dispersed, and the component (7) was added and molded by a molding machine.

[Comparative Example 5: Lipstick] (1) Polyglyceryl polyisostearate (Comparative Example 1)
60.0, (2) diisostearyl malate 7.5, (3) beeswax 15.0, (4) carnauba wax 4.0, (5) lanolin 3.0, (6) legal dye
Pigment 10.0, (7) Perfume / Antioxidant Proper amount (manufacturing method) According to Example 5.

[Example 6: Powder cosmetics] Powder phase composition: (1) sericite 50.0, (2) mica 20.0, (3) talc 12.0, (4) silica beads 5 .0 Oil phase composition: (5) squalane 7.0, (6) polyglyceryl isostearate (same as Example 1) 5.0,
(7) Preservative proper amount, (8) perfume proper amount (production method) The components (1) to (4) were mixed with a Henschel mixer, and the mixture was heated and dissolved and mixed (5).
After the components (7) to (7) are sprayed and kneaded, the components (8) are added and pulverized with an atomizer. After sieving, it is filled in a gold plate and compression molded.

[Comparative Example 6: Powder cosmetics] Powder phase composition: (1) sericite 50.0, (2) mica 20.0, (3) talc 12.0, (4) silica beads 5 .0 Oil phase composition: (5) squalane 7.0, (6) polyglyceryl polyisostearate (same as Comparative Example 1)
0, (7) Preservative proper amount, (8) Perfume proper amount (production method) As in Example 6.

As described above, 20 cosmetic engineers were requested to use the samples of Examples 1 to 6 and Comparative Examples 1 to 6, and the evaluation of each sample was evaluated A; fairly excellent evaluation B; excellent. Evaluation C: Normal evaluation D: Poor evaluation E: Represented as being considerably poor.

The above results are shown in Table 1. The numbers in the table are
The number of people evaluated as A, B, C, D or E is shown.

[0057]

[Table 1]

Furthermore, 5 ° C., room temperature, 25 ° C., 40 ° C. and 3 months under cycle fluctuation of −10 ° C. and 40 ° C.
The properties (separation, discoloration, odor, etc.) before and after storage at 0 ° C. for 1 month in normal humidity and the stability judged from these are shown as ◯: good Δ: normal ×: poor.

The above results are shown in Table 2 below.

[0060]

[Table 2]

From Tables 1 and 2, the tri [2-
When (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is added to various cosmetics, any of film feeling, body feeling, and state,
It is apparent that a product which is superior to the conventional polyglyceryl polyisostearate having a low viscosity and also has good stability can be obtained.

Further, with respect to the lipsticks of Example 5 and Comparative Example 5, the following four kinds of tests were conducted, and the criteria shown in Table 3
Evaluation was made as Δ or ×, and the results are summarized in Table 4.

Horizontal test: In a constant temperature device at 40, 45 and 50 ° C., in a state where all the lipsticks formed in a shell shape and attached to the container were fed out, 24 hours after being left horizontal,
Visually observe the deformation, that is, the bending and bending.

Penetration test: After molding the lipstick, the mixture was allowed to stand at 25 ° C. for 24 hours and then, using a rheometer (load pressure: 0 to 2 kg) equipped with an adapter having a diameter of 3 mm, T speed of 6 cm / min. Penetration depth 1 cm, stress at 25 ° C (g)
Ask for.

Breaking strength test: A lipstick formed into a shell shape and attached to a container was allowed to stand at 25 ° C. for 24 hours and then fed out, and a rheometer equipped with a tooth-shaped pushing rod as an adapter (load pressure: 0 ~ 2 kg),
The predetermined position is pressed at a T speed of 6 cm / min at 25 ° C., and the stress (g) at breakage is obtained.

Shear strength test: After molding the lipstick, allowed to stand at 25 ° C. for 24 hours, then using a rheometer (load pressure: 0 to 200 g) equipped with a piano wire as an adapter, T speed was set to 2 cm / min. , Shear stress at 25 ℃ (g)
Ask for.

[0067]

[Table 3]

[0068]

[Table 4]

From Table 4, the tri- [2- (1,3,3
It is demonstrated that the lipstick to which 3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is added has excellent stability, especially at high temperatures.

[0070]

As described above, according to the present invention,
When applied to skin, hair, etc., an excellent film feeling, a cosmetic material that is desired to bring a feeling of use such as richness, that is, make-up, skin care and hair care products, and a raw material compound useful in a skin composition are Provided. When this raw material compound is blended, the feeling of use is improved and the viscosity,
A cosmetic and dermatological composition having excellent stability can be obtained without causing changes in physical properties such as hardness.

─────────────────────────────────────────────────── ───

[Procedure amendment]

[Submission date] March 28, 2002 (2002.3.2)
8)

[Procedure Amendment 1]

[Document name to be amended] Statement

[Name of item to be amended] Claims

[Correction method] Change

[Correction content]

[Claims]

[Chemical 1] [In the formula, 1 to 12 substituents in R are represented by the following chemical formula (II):

[Chemical 2] And the rest of R represents H, and n represents an integer of 0 to 8].
A raw material compound characterized by the above .

[Procedure Amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0007

[Correction method] Change

[Correction content]

[0007] That is, the present invention is a cosmetic or skin
A raw material compound of the following formula (I):

[Procedure 3]

[Document name to be amended] Statement

[Correction target item name] 0011

[Correction method] Change

[Correction content]

Represents a 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group represented by the following, the rest R represents H, and n represents an integer of 0 to 8].
A raw material that is polyglyceryl isostearate represented by
A compound is provided. ─────────────────────────────────────────────────── ───

[Procedure amendment]

[Submission date] May 1, 2002 (2002.5.1)

[Procedure Amendment 1]

[Document name to be amended] Statement

[Correction target item name] Full text

[Correction method] Change

[Correction content]

[Document name] Statement

Title of the invention Cosmetics and dermatological compositions

[Claims]

[Chemical 1] [In the formula, 1 to 12 substituents in R are represented by the following chemical formula (II):

[Chemical 2] And the rest of R represents H, and n represents an integer of 0 to 8].
Characterized by containing at least one or more compounds
Cosmetics .

[Chemical 3] [In the formula, 1 to 12 substituents in R are represented by the following chemical formulas:
(II):

[Chemical 4] , The remaining R represents H, and n represents an integer of 0-8.
] Is a polyglyceryl isostearate
Characterized by containing at least one or more compounds
A composition for skin.

[Chemical 5] [In the formula, 1 to 12 substituents in R are represented by the following chemical formulas:
(II):

[Chemical 6] , The remaining R represents H, and n represents an integer of 0-8.
] Is a polyglyceryl isostearate
Viscosity modifiers of the cosmetic or dermatological composition, characterized by containing a compound.

[Chemical 7] [In the formula, 1 to 12 substituents in R are represented by the following chemical formulas:
(II):

[Chemical 8] , The remaining R represents H, and n represents an integer of 0-8.
] Is a polyglyceryl isostearate
Stabilizer properties of cosmetic or dermatological composition, characterized by containing a compound.

[Chemical 9] [In the formula, 1 to 12 substituents in R are represented by the following chemical formulas:
(II):

[Chemical 10] , The remaining R represents H, and n represents an integer of 0-8.
] Is a polyglyceryl isostearate
A texture modifier of the cosmetic or dermatological composition, characterized by containing a compound.

[Chemical 11] [In the formula, 1 to 12 substituents in R are represented by the following chemical formulas:
(II):

[Chemical 12] , The remaining R represents H, and n represents an integer of 0-8.
] Is a polyglyceryl isostearate
Film formers cosmetic or dermatological composition, characterized by containing a compound.

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a raw material compound useful in make-up, skin care and hair care products, which are desired to bring about an excellent feeling of use when applied to skin, hair and the like, and a cosmetic containing the same. And dermatological compositions. More specifically, the present invention relates to a raw material compound which is useful in cosmetics and dermatological compositions having excellent feelings of use such as film feeling and body feeling and maintaining desirable physical properties.

[0002]

2. Description of the Related Art Conventionally, hydrocarbon-based liquid oils such as wax and heavy liquid paraffin have been used in order to improve the feeling of use of cosmetics, skin compositions and the like, particularly the feeling of film and the feeling of body. It was For example, Japanese Patent Application Laid-Open No. 2001-158718 discloses a lipstick composition containing a predetermined amount of a polyethylene wax having an average molecular weight of 300 to 700 and a liquid oil component having one or more hydroxyl groups in the structure. It is described that a product excellent in sex, spreadability, luster and makeup lasting can be obtained. However, even if these raw materials are blended, it has not been possible to obtain a sufficiently satisfactory feeling of use such as a desired film feeling and a feeling of body.

It has also been reported that the use of polar oils such as fatty acid esters can enhance the variation in use feeling and satisfaction. For example, Japanese Patent Laid-Open No. 10-13
9628 discloses a boron nitride powder and a foundation containing diglyceryl diisostearate and / or diglyceryl triisostearate in a binder,
It has been shown that cosmetics such as eye shadow have excellent adhesiveness, spread thinly and have a transparent feeling. Further, in JP-A-2000-302623, polyglyceryl diisostearate, carboxyvinyl polymer and / or
Alternatively, an oily cosmetic containing an alkyl-modified carboxyvinyl polymer is disclosed, and it is said that a product having good spread and spread, capable of being uniformly applied, and easy to remake is obtained. Japanese Unexamined Patent Publication No. 2000-319219 discloses a homogeneous, highly stable and agglomerate containing an ester of a fatty acid or an alcohol having a saturated or branched carbon chain having 24 to 28 carbon atoms and a silicone compound. A cosmetic composition rich in properties is disclosed. In addition, a saturated hydrocarbon having a side chain and a predetermined melting point, and an oily solid cosmetic containing diglyceryl diisostearate and / or diglyceryl triisostearate have excellent shape retention and spread easily during application. It has also been shown to have good smoothness and an excellent feeling of use (Japanese Patent No. 2821693).

[0004]

The isostearoyl group in the above polyglyceryl isostearate is IUP.
An isostearoyl group according to the AC nomenclature, ie 1
Not limited to the 6-methylheptadecanoyl group, it is an acyl group having a carbon number of 18 and having a branched structure at various sites. Therefore, the structure of polyglyceryl isostearate is diversified. Commercial products that are specifically mentioned as such conventional polyglyceryl isostearate include NIKKOL DGDIS (manufactured by Nikko Chemicals), which is diglyceryl diisostearate, Emalex DISG-2 (manufactured by Nippon Emulsion Co., Ltd.), Matsunate DI (Matsumoto Pharmaceutical Co., Ltd.). ), Unigri GI-202 (manufactured by NOF Corporation), Cosmol 42 (manufactured by Nisshin Oil Co., Ltd.), Triglyceryl diisostearate Emalex DISG-3 (manufactured by Nippon Emulsion), Unigri GI-203 (manufactured by NOF Corporation) ), And NIKKOL which is decaglyceryl diisostearate
Decaglyn2-IS (manufactured by Nikko Chemicals),
Emalex DISG-10 (manufactured by Nippon Emulsion Co., Ltd.) and the like. Although these can improve the feeling of use to some extent when incorporated into a cosmetic, it is difficult to properly maintain physical properties such as viscosity and hardness, and a satisfactory cosmetic or dermatological composition is provided. I couldn't do that.

Therefore, the present invention is useful as a raw material for make-up, skin care and hair care products, and skin compositions, which can provide an excellent feeling of use such as a filmy feeling and a rich feeling when applied to skin, hair and the like. It is an object of the present invention to provide a useful compound which does not impair the physical properties desired for cosmetics and the like after compounding, the high temperature stability of oily solid cosmetics and the like.

[0006]

In view of the above situation, the present inventors have conducted diligent research and as a result, found that a polyglycerin ester containing a specific isostearoyl group as a fatty acid composition has a very high viscosity. By blending the heading, such polyglyceryl isostearate,
The present invention has been completed by clarifying that it is possible to prepare a cosmetic or dermatological composition that has a good feeling in use and that retains preferable physical properties.

That is, the present invention has the following chemical formula (I):

[0008]

[Chemical 13]

[In the formula, the substituents 1 to 12 in R are represented by the following chemical formula (II):

[0010]

[Chemical 14]

Represents a 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group represented by the following, the rest R represents H, and n represents an integer of 0 to 8].
A compound that is a polyglyceryl isostearate represented by
Cosmetics containing at least one product
And a dermatological composition .

Suitable as the above cosmetics are emulsions,
Creams, sunscreens, lipstick compositions or powder cosmetics are included, but lipstick compositions such as lipsticks and lip glosses are particularly preferable.

[0013]

BEST MODE FOR CARRYING OUT THE INVENTION The following chemical formula (I), which is a raw material compound for cosmetics and dermatological compositions of the present invention:

[0014]

[Chemical 15]

[Wherein the substituents 1 to 12 of R are the following chemical formula (II):

[0016]

[Chemical 16]

A 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group represented by the following, the rest R represents H, and n represents an integer of 0 to 8].
In polyglyceryl isostearate represented by,
Those in which 1 to 4 Rs, preferably 3 Rs, are substituents represented by the chemical formula (II) are preferable as raw material compounds capable of imparting a favorable usability to cosmetics and dermatological compositions. However, the viscosity and hardness of the cosmetics are appropriately maintained, and the high temperature stability is not impaired.

In the above chemical formula (II), n is 0 to
8, more preferably 0 to 2, and n is 0, that is, mono- or poly- [2-
(1,3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is preferred. When n is 9 or more, the molecular weight becomes too large, which causes undesired feeling of use such as stickiness in the blended cosmetics, which is not preferable.

The compound of the present invention is specifically tri [2- (1,3,3-trimethyl) butyl-5,7,7.
-Trimethyloctanoic acid] diglyceryl, di [2-
(1,3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl, tetra [2- (1,
3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl and di [2- (1,3,3-)
Trimethyl) butyl-5,7,7-trimethyloctanoic acid] triglyceryl, tri [2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] triglyceryl, tetra [2- ( Examples include 1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] triglyceryl, particularly tri [2- (1,3,3-).
Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is preferable in that it can bring more excellent film feeling and rich feeling to cosmetics but does not impair physical properties.

As described above, these compounds have higher viscosities than conventional products, but the viscosities at 25 ° C. are especially 5000 to 35000 mPa · s, more preferably 15.
000-30000 mPa · s, most preferably about 22
Those having a viscosity of 000 mPa · s are suitable for use as a raw material compound for cosmetics, which can impart an excellent film feeling and richness and do not cause undesirable changes in physical properties such as a decrease in viscosity and a decrease in hardness. It Further, when the raw material compound of the present invention is added, a composition having little change with time in physical properties such as viscosity and hardness can be obtained, so that it is suitable for topical application even after long-term storage, and forms a desirable film at the application site. A skin composition capable of exerting a medicinal effect can be prepared.

The method for producing polyglyceryl isostearate is based on the generally known method for producing polyglyceryl isostearate. That is, glycerol is dehydrated and condensed at about 250 ° C. in the presence of a base such as sodium hydroxide to prepare polyglycerol having an appropriate degree of polymerization. Then, in the presence of a suitable catalyst such as an alkali catalyst, 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid is added to carry out the esterification reaction.

The cosmetics to which the above-mentioned raw material compounds can be blended are not particularly limited, and include skin cosmetics such as lotions, milky lotions, cleansing creams, nutritional creams, lip balms, hand creams and sunscreens, and makeup base creams. , Lipstick compositions such as liquid and powder foundation, eye color, cheek color, lipstick, lip gloss, make-up cosmetics such as eyebrow and control color, hair cosmetics such as hair cream and hair treatment, body lotion, Body cosmetics such as body creams and leg creams can be mentioned, but it is desirable that they are excellent in film feeling and rich feeling that give a rich feeling of use, emulsions, creams, sunscreens, lipstick compositions or powder cosmetics. , Especially lipstick, It preferred in lipstick compositions such gloss.

The amount of the raw material compound of the present invention blended in the cosmetics and dermatological compositions may vary depending on the desired properties of the cosmetics and dermatological compositions and the degree of feel to be imparted. , 3 to 10% by weight for liquid products such as emulsions, 3 to 25% by weight for creams, 0.5 to 15% by weight for powder cosmetics, and oil-based cosmetics such as lipstick compositions. In the case of (1), it is preferable to add 0.1 to 60% by weight from the viewpoint of giving a film feeling, a rich feeling, etc. and a rich feeling of use.

Two or more kinds of such raw material compounds differ in the degree of polymerization of polyglycerol and / or the content of 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoyl group. You may mix and mix.

The cosmetics of the present invention will be outlined below.

First, in addition to the above-mentioned raw material compounds, various components generally used in cosmetics can be added to the emulsified composition such as emulsion and cream, if necessary. Examples of these components include oily components, surfactants, moisturizers, higher alcohols, sequestering agents, thickeners or dispersion stabilizers, gelling agents for oily components, ultraviolet absorbers, blood circulation promoters, various extractions. Liquids, inorganic and organic pigments, clay minerals and organic modified products thereof, inorganic and organic pigments whose surface is modified with metal soap or silicone, colorants such as organic dyes, preservatives, antioxidants, pigments, thickeners. Agents, pH adjusters, fragrances, cooling agents, antiperspirants, bactericides, skin activating agents and the like.

As the oily component, fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, esters, essential oils, silicone oils, more specifically, avocado oil, camellia oil, turtle oil, macadamia nuts Oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil,
Castor oil, linseed oil, safflower oil, evening primrose oil, cottonseed oil, eno oil, soybean oil, peanut oil, teaseed oil, kaya oil, rice bran oil, cinnamon oil, Japanese tung oil, jojoba oil, germ oil,
Triglycerin, glyceryl trioctanoate, glyceryl triisopalmitate, cocoa butter, coconut oil, horse fat, hardened coconut oil, palm oil, beef tallow, sheep fat, hardened beef tallow, palm kernel oil, lard, beef bone fat, mokuro kernel Oil, hydrogenated oil, beef tallow, mokuro, hydrogenated castor oil, beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, ivorot wax,
Whale wax, montan wax, nuka wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax,
Lanolin fatty acid isopropyl, hexyl laurate, reduced lanolin, hard lanolin, shellac wax, polyoxyethylene lanolin alcohol ether, polyoxyethylene lanolin alcohol acetate, polyoxyethylene cholesterol ether, lanolin fatty acid polyethylene glycol, polyoxyethylene hydrogenated lanolin alcohol ether, Liquid paraffin, ozokerite, squalene, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, silicone oil and the like can be mentioned.

Among the surfactants, lipophilic nonionic surfactants include, for example, sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquiole. Sorbate, sorbitan trioleate, penta-2-ethylhexylate diglycerol sorbitan, tetra-2-ethylhexylate diglycerol sorbitan, and other sorbitan fatty acid esters, monocottonseed oil fatty acid glycerin, monoerucate glycerin, sesquioleate glycerin, monostearate glycerin , Α, α'-glycerin fatty acids such as glycerin pyroglutamate oleate, propylene glycol fatty acid esters such as propylene glycol monostearate, hardened castor Oil derivatives, glycerin alkyl ethers and the like. Examples of the hydrophilic nonionic surfactant include polyoxyethylene sorbitan fatty acid esters, polyoxyethylene sorbit fatty acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene alkyl ethers, Polyoxyethylene alkyl phenyl ethers, polyoxyethylene polyoxypropylene block polymers, polyoxyethylene polyoxypropylene alkyl ethers, tetrapolyoxyethylene / tetrapolyoxypropylene ethylenediamine condensates, polyoxyethylene castor oil derivatives , Polyoxyethylene hydrogenated castor oil derivative, polyoxyethylene beeswax lanolin derivative, alkanolamides, polyoxyethylene propylene glycol Le fatty acid esters, polyoxyethylene alkyl amines,
Examples thereof include polyoxyethylene fatty acid amides, sucrose fatty acid esters, polyoxyethylene nonylphenylformaldehyde condensates, alkylethoxydimethylamine oxides, trioleylphosphoric acids and the like. Examples of the anionic surfactant include fatty acid soap, higher alkyl sulfate ester salts, alkyl ether sulfate ester salts, N-acyl sarcosinic acids, higher fatty acid amide sulfonates, phosphate ester salts, sulfosuccinates, alkylbenzene sulfonates. , Higher fatty acid ester sulfate ester salts, sulfated oil, polyoxyethylene alkyl ether carboxylic acids, polyoxyethylene alkyl allyl ether carboxylate salts, α-olefin sulfonates, higher fatty acid ester sulfonate salts, secondary alcohol sulfate ester salts , Higher fatty acid alkylolamide sulfate, sodium lauroyl monoethanolamide succinate, ditriethanolamine N-palmitoyl aspartate, sodium caseinate, etc. It is. Examples of the cationic surfactant include alkyl trimethyl ammonium salts, alkyl pyridinium salts, alkyl quaternary ammonium salts, alkyl dimethyl benzyl ammonium salts, alkyl isoquinolinium salts, dialkyl molyphonium salts, alkyl amine salts, alcohol fatty acid derivatives. , Benzalkonium chloride, benzethonium chloride and the like. Examples of the amphoteric surfactant include imidazoline-based amphoteric surfactants and betaine-based surfactants.

Examples of moisturizers include polyethylene glycol, propylene glycol, glycerin, 1,3-
Butylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, caronic acid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, bile salt, dl-pyrrolidone carboxylate, short chain soluble collagen , Diglycerin (ethylene oxide)
Examples include propylene oxide adducts and extracts from other natural organisms.

Examples of higher alcohols include straight chain alcohols such as lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol and cetostearyl alcohol, monostearyl glycerin ether (butyl alcohol), 2-decyltetradecyl alcohol. Examples thereof include branched chain alcohols such as knoll, lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, and octyldodecanol.

Examples of the sequestering agent include 1-hydroxyethane-1,1-diphosphonic acid, 1-hydroxyethane-1,1-diphosphonic acid tetrasodium salt,
Disodium edetate, trisodium edetate, tetrasodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid,
Examples thereof include citric acid, ascorbic acid, succinic acid, and edetic acid.

Water-soluble polymers useful as thickeners or dispersion stabilizers include araavia gum, tragacanth gum,
Plant-based macromolecules such as galactan, guar gum, carob gum, karaya gum, carrageenan, pectin, agar, starch, glycyrrhizinic acid, microbial macromolecules such as xanthan gum, dextran, succinoglucan, and vullan, collagen, casein, albumin, gelatin, etc. Natural water-soluble polymers including animal-based polymers; semi-synthetic water-soluble polymers such as starch-based polymers, cellulose-based polymers, alginic acid-based polymers; vinyl-based polymers, polyoxyethylene-based polymers, polyoxy Synthetic water-soluble polymer such as ethylene polyoxypropylene copolymer copolymer, acrylic polymer, polyethyleneimine, cationic polymer;
Examples include inorganic water-soluble polymers such as bentonite, magnesium aluminum silicate, laponite, hectorite, and anhydrous silicic acid.

Examples of the gelling agent for the oily component include, but are not limited to, dextrin fatty acid ester, glycerin fatty acid ester and metal soap.
Examples of the dextrin fatty acid ester include dextrin myristate [trade name "Leopearl MKL" manufactured by Chiba Milling Co., Ltd.], dextrin palmitate [trade names "Reopearl KL", "Reopearl TL" manufactured by Chiba Milling Co., Ltd.]. , (Palmitic acid / 2-ethylhexanoic acid) dextrin [trade name "Reopearl TT",
Chiba Flour Milling Co., Ltd.] and the like. Examples of the glycerin fatty acid ester include glyceryl behenate, glyceryl octastearate, glyceryl eicoate, and the like, and one or more of them may be used in combination. Specifically, a trade name “TAISET 26” (manufactured by Taiyo Kagaku Co., Ltd.) containing 20% glyceryl behenate, 20% glyceryl octastearate and 60% hydrogenated palm oil,
A trade name “TAISET 50” (manufactured by Taiyo Kagaku Co., Ltd.) containing 50% glyceryl behenate and 50% glyceryl octastearate can be mentioned. Examples of the metal soap include salts of saturated or unsaturated fatty acids having 10 to 26 carbon atoms and a divalent or higher metal, such as aluminum stearate, aluminum palmitate, aluminum myristate, aluminum laurate, magnesium stearate, and palmitic acid. UV absorbers such as magnesium, magnesium myristate, magnesium laurate, zinc stearate, zinc palmitate, zinc myristate, zinc laurate, calcium stearate, calcium palmitate, calcium myristate, calcium laurate, etc., include benzoic acid. Acid UV absorbers, anthranilic acid UV absorbers, salicylic acid UV absorbers; cinnamic acid UV absorbers, benzophenone UV absorbers, triazole UV absorbers, etc.

Examples of the blood circulation promoter include nonyl acid warenylamide, nicotinic acid benzyl ester, nicotinic acid β-butoxyethyl ester, capsaicin, zingerone, cantharitin tincture, ictamol, caffeine, tannic acid, α-borneol, nicotinic acid tocopherol, Examples include inositol hexanicotinate, cyclanderate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthin, γ-oryzanol and the like.

As other drug components, ascorbic acid,
Examples include vitamins such as pyridoxine hydrochloride, various hormones, amino acids, anti-inflammatory agents such as lysozyme chloride, whitening agents such as sulfur, astringents, and cooling agents.

Various extracts are extracted from natural products and have been shown to bring beneficial effects upon application. Dokudami extract, oyster extract, licorice extract, peony extract, loofah extract, yukinoshita extract, fennel extract, primrose extract. Extract, rose extract, dioxin extract, lemon extract, shikon extract, aloe extract,
Ginger root extract, eucalyptus extract, horse mackerel extract, sage extract, thyme extract, tea extract, seaweed extract, cucumber extract, clove extract, raspberry extract, melissa extract, carrot extract, horse chestnut extract, peach extract, peach leaf extract, mulberry extract, clam extract. Examples include extracts, hamamelis extract, placenta extract, thymus extract, silk extract, licorice extract and the like.

Next, compact type or stick type foundation, eye color, cheek color,
As components of powder cosmetics that can be provided as deodorant sticks, antiperspirant sticks, etc., in addition to the above oily components and cosmetic compounding ingredients, inorganic powders as powder ingredients,
Bright powders, organic powders, pigment powders, composite powders,
And the like, such as spherical, plate-like and needle-like shapes, haze-like particles, fine particles, particle size such as pigment grade, and particle structure such as porous and non-porous are appropriately used.

Specifically, titanium oxide, black titanium oxide,
Conger, ultramarine, red iron oxide, yellow iron oxide, black iron oxide, zinc oxide, aluminum oxide, silicon dioxide, magnesium oxide, zirconium oxide, magnesium carbonate, calcium carbonate, chromium oxide, chromium hydroxide, carbon black, aluminum silicate, silica Magnesium acid salt, magnesium aluminum silicate, mica, synthetic mica, synthetic sericite, sericite, talc, kaolin, silicon carbide, barium sulfate, bentonite, smectite, inorganic powders such as boron nitride, bismuth oxychloride, titanium mica, Iron oxide coated mica, iron oxide mica titanium, tar dye, organic pigment treated mica titanium, bright powders such as aluminum powder, nylon powder, polymethylmethacrylate, acrylonitrile-methacrylic acid copolymer powder, vinyl chloride Down - methacrylic acid copolymer powder, polystyrene powder, polymethylsilsesquioxane powder, wool powder, silk powder,
Crystalline cellulose, organic powders such as N-acyl lysine, fine particles titanium oxide-coated titanium mica, fine particles zinc oxide-coated titanium mica, barium sulfate-coated titanium mica, titanium oxide-containing silicon dioxide, zinc oxide-containing silicon dioxide, and other composite powders, etc. Is mentioned. Further, these powders are blended by surface treatment by a generally known method such as silicones, fluorine compounds, metal soaps, oils, etc. for the purpose of improving the durability of makeup, improving the adhesion to the skin, adjusting the feel and the like. You may.

Oily cosmetics such as lipstick compositions are solid,
It can be provided as a semi-solid form, a liquid form, or a W / O emulsion, and in addition to the raw material compound of the present invention, the above-mentioned oils and fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, and esters. It is possible to use, as a base, an oily component such as a salt, a surfactant, an essential oil or a silicone oil, which is appropriately blended. Furthermore, for the purpose of improving the make-up effect and touch, the above powders, polyhydric alcohols, sugars, sugar derivatives,
Amino acids, amino acid derivatives, moisturizing agents such as salts, benzoic acid, preservatives, antioxidants, ultraviolet absorbers, skin-refining ingredients, cooling agents, and fragrances can be added.

The cosmetics of the present invention outlined above are those in which the blending amounts of various components are determined based on the common general technical knowledge in the technical field, and can be produced by a generally known method.

The dermatological composition of the present invention can be provided in the form of lotions, emulsions, creams, ointments and the like according to cosmetics.
For example, analgesics, antipruritics, astringents, antiphlogistics; germicides / disinfectants; wound protectors; purulent disease agents; emollients containing corrosive agents; And so on. The amounts of the components to be mixed, the manufacturing method and the like are appropriately selected based on the common general technical knowledge in the technical field.

[0042]

The present invention will be described in more detail with reference to examples, but the present invention is not limited thereto. All blending amounts are expressed in weight percent.

Example 1: Emulsion Oil phase composition: (1) stearic acid 2.0, (2) cetyl alcohol 1.5, (3) decamethylpentacyclosiloxane 3.0, (4) dimethyl poly. Siloxane (6c
s) 5.0, (5) polyglyceryl isostearate (viscosity at 25 ° C .: 22000 mPa · s) 3.0,
(6) Vaseline 0.5, (7) Polyoxyethylene monooleate 2.0 Water phase composition: (8) Carboxyvinyl polymer 0.2,
(9) 1,3-butylene glycol 5.0, (10) glycerin 3.0, (11) potassium hydroxide 1.0, (1
2) Methylparaben, a proper amount, (13) ion-exchanged water, the rest (production method) of the aqueous phase parts (8) to (13) are mixed at 70 ° C.,
What mixed and melt | dissolved oil phase parts (1)-(7) was added to this, and emulsification was performed, and the cooling process was carried out and the emulsion was obtained. The polyglyceryl isostearate contains tri [2-
(1,3,3-Trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl was used. This compound was produced by adding 2- (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid (manufactured by Nissan Chemical Industries, Ltd.) to diglycerin to carry out an esterification reaction. Yes, viscosity at 25 ° C is 22000 mP
It was a.s.

Comparative Example 1: Emulsion Oil phase composition: (1) stearic acid 2.0, (2) cetyl alcohol 1.5, (3) decamethylpentacyclosiloxane 3.0, (4) dimethyl poly. Siloxane 6cs
5.0, (5) polyglyceryl polyisostearate (manufactured by Nisshin Oil Co., Ltd., Cosmol 43; viscosity at 25 ° C .: 250 mPa · s) 3.0, (6) vaseline 0.
5, (7) polyoxyethylene monooleate 2.0 aqueous phase composition: (8) carboxyvinyl polymer 0.2,
(9) 1,3-butylene glycol 5.0, (10) glycerin 3.0, (11) potassium hydroxide 1. 0, (12) Methylparaben, appropriate amount, (13) Ion-exchanged water, balance (manufacturing method) As in Example 1.

Example 2: Cream Oil phase composition: (1) octamethyltetracyclosiloxane 3.0, (2) methylphenylpolysiloxane 3.
0, (3) Polyglyceryl isostearate (Example 1
5.0), (4) stearic acid 2.0, (5) cetyl alcohol 1.5, (6) stearyl alcohol 0.5, (7) white petrolatum 1.0, (8) tri-2-ethylhexanoic acid. Glyceryl 3.0, (9) cetyl octanoate 3.0, (10) glyceryl monostearate 3.
0, (11) polyoxyethylene sorbitan monostearate 1.0, (12) ethyl paraben 0.
2. (13) Butylparaben 0.1, (14) Perfume Amount of water phase composition: (15) Smecton SA (Kunimine Industries Co. synthetic clay mineral) 1.0, (16) 1,3-butylene glycol 10. 0, (17) glycerin 5.0, (1
8) potassium hydroxide 1.0, (19) magnesium ascorbyl phosphate 0.02, (20) sodium hyaluronate 0.05, (21) ion-exchanged water balance (production method) aqueous phase part (15) to ( 18), (20) and (21) are mixed at 70 ° C., and the oil phase parts (1) to (1) are added thereto.
4) was mixed and dissolved, and emulsified. Then, when the emulsion is cooled to about 40 ° C,
A solution obtained by dissolving (19) in a small amount of (21) was added, followed by stirring and mixing, and further cooling to obtain an emulsion.

Comparative Example 2: Cream Oil phase composition: (1) octamethyltetracyclosiloxane 3.0, (2) methylphenylpolysiloxane 3.
0, (3) polyglyceryl polyisostearate (the same as in Comparative Example 1) 5.0, (4) stearic acid 2.0,
(5) Cetyl alcohol 1.5, (6) Stearyl alcohol 0.5, (7) White petrolatum 1.0, (8) Glyceryl tri-2-ethylhexanoate 3.0, (9) Cetyl octanoate 3.0 , (10) glyceryl monostearate 3.0, (11) polyoxyethylene sorbitan monostearate 1.0, (12) ethyl paraben 0.2, (13) butyl paraben 0.1, (14) perfume suitable amount Aqueous phase composition: (15) Smecton SA, (synthetic clay mineral manufactured by Kunimine Industry Co., Ltd.) 1.0, (16) 1,3-butylene glycol 10.0, (17) glycerin 5.0, (1
8) Potassium hydroxide 1.0, (19) magnesium ascorbate phosphate 0.02, (20) sodium hyaluronate 0.05, (21) ion-exchanged water balance (manufacturing method) According to Example 2.

[Example 3: Sunscreen] Oil phase composition: (1) Dimethyl polysiloxane 5.0,
(2) Methylphenylpolysiloxane 5.0, (3) Polyglyceryl isostearate (same as in Example 1) 1
0.0, (4) (alkyl acrylate / dimethicone) copolymer 1.0, (5) stearic acid 1.0, (6) palmitic acid 1.0, (7) cetyl alcohol 1.5,
(8) White petrolatum 1.0, (9) 4-tert-butyl-4′-methoxydibenzoylmethane 2.0, (1
0) octyl methoxycinnamate 5.0, (11) glyceryl monostearate 3.0, (12) polyoxyethylene sorbitan monostearate 1.0,
(13) Ethylparaben 0.2, (14) Butylparaben 0.1, (15) Perfume Amount of water phase composition: (16) Carboxyvinyl polymer 0.1
5, (17) 1,3-butylene glycol 5.0, (1
8) Potassium hydroxide 1.0, (19) Ion-exchanged water Remaining (Production method) As in Example 2.

[Comparative Example 3: Sunscreen] Oil phase composition: (1) Dimethylpolysiloxane 5.0,
(2) Methylphenyl polysiloxane 5.0, (3) Polyglyceryl polyisostearate (same as Comparative Example 1)
10.0, (4) (alkyl acrylate / dimethicone)
Copolymer 1.0, (5) Stearic acid 1.0, (6)
Palmitic acid 1.0, (7) cetyl alcohol 1.5,
(8) White petrolatum 1.0, (9) 4-tert-butyl-4′-methoxydibenzoylmethane 2.0, (1
0) octyl methoxycinnamate 5.0, (11) glyceryl monostearate 3.0, (12) polyoxyethylene sorbitan monostearate 1.0,
(13) Ethylparaben 0.2, (14) Butylparaben 0.1, (15) Perfume Amount of water phase composition: (16) Carboxyvinyl polymer 0.1
5, (17) 1,3-butylene glycol 5.0, (1
8) Potassium hydroxide 1.0, (19) Ion-exchanged water Remaining (Production method) As in Example 2.

Example 4: W / O Cream Oil phase composition: (1) Dimethyl polysiloxane 10.0,
(2) Methylphenyl polysiloxane 5.0, (3) Polyglyceryl isostearate (same as in Example 1) 5.
0, (4) (alkyl acrylate / dimethicone) copolymer 5.0, (5) polyoxyethylene-modified organopolysiloxane 3.0, (6) octyl methoxycinnamate 5.0, (7) perfume proper amount water phase part Composition: (8) Smecton SA (synthetic clay mineral manufactured by Kunimine Industries Co., Ltd.) 3.0, (9) 1,3-butylene glycol 5.0, (10) glycerin 5.0, (11) L-
Sodium glutamate 2.0, (12) ion-exchanged water The balance (production method) The oil phase parts (1) to (6) were mixed at 70 ° C, and the aqueous phase parts (8) to (12) were heated to 70 ° C. What was mixed and dissolved was added and emulsified. Then, at the stage where the emulsion was cooled to about 40 ° C., after adding (7),
Stir-mixing and further cooling gave W / O cream.

[Comparative Example 4: W / O cream] Oil phase composition: (1) Dimethyl polysiloxane 10.0,
(2) Methylphenyl polysiloxane 5.0, (3) Polyglyceryl isostearate (same as Comparative Example 1)
0, (4) (alkyl acrylate / dimethicone) copolymer 5.0, (5) polyoxyethylene-modified organopolysiloxane 3.0, (6) octyl methoxycinnamate 5.0, (7) perfume proper amount water phase part Composition: (8) Smecton SA (synthetic clay mineral manufactured by Kunimine Industries Co., Ltd.) 3.0, (9) 1,3-butylene glycol 5.0, (10) glycerin 5.0, (11) L-
Sodium glutamate 2.0, (12) ion-exchanged water balance (manufacturing method) According to Example 4.

[Example 5: Lipstick] (1) Polyglyceryl isostearate (same as in Example 1) 60.0, (2) Diisostearyl malate 7.
5, (3) beeswax 15.0, (4) carnauba wax 4.0, (5) lanolin 3.0, (6) legal dye / pigment 10.0, (7) perfume / antioxidant, proper amount (production method ) After heating, melting and mixing the components (1) to (5), the component (6) was added and well dispersed, and the component (7) was added and molded by a molding machine.

[Comparative Example 5: Lipstick] (1) Polyglyceryl polyisostearate (Comparative Example 1)
60.0, (2) diisostearyl malate 7.5, (3) beeswax 15.0, (4) carnauba wax 4.0, (5) lanolin 3.0, (6) legal dye
Pigment 10.0, (7) Perfume / Antioxidant Proper amount (manufacturing method) According to Example 5.

[Example 6: Powder cosmetics] Powder phase composition: (1) sericite 50.0, (2) mica 20.0, (3) talc 12.0, (4) silica beads 5 .0 Oil phase composition: (5) squalane 7.0, (6) polyglyceryl isostearate (same as Example 1) 5.0,
(7) Preservative proper amount, (8) perfume proper amount (production method) The components (1) to (4) were mixed with a Henschel mixer, and the mixture was heated and dissolved and mixed (5).
After the components (7) to (7) are sprayed and kneaded, the components (8) are added and pulverized with an atomizer. After sieving, it is filled in a gold plate and compression molded.

[Comparative Example 6: Powder cosmetics] Powder phase composition: (1) sericite 50.0, (2) mica 20.0, (3) talc 12.0, (4) silica beads 5 .0 Oil phase composition: (5) squalane 7.0, (6) polyglyceryl polyisostearate (same as Comparative Example 1)
0, (7) Preservative proper amount, (8) Perfume proper amount (production method)
According to Example 6.

As described above, 20 cosmetic engineers were requested to use the samples of Examples 1 to 6 and Comparative Examples 1 to 6, and the evaluation of each sample was evaluated A; fairly excellent evaluation B; excellent. Evaluation C: Normal evaluation D: Poor evaluation E: Represented as being considerably poor.

The above results are shown in Table 1. The numbers in the table are
The number of people evaluated as A, B, C, D or E is shown.

[0057]

[Table 1]

Furthermore, 5 ° C., room temperature, 25 ° C., 40 ° C. and 3 months under cycle fluctuation of −10 ° C. and 40 ° C.
The properties (separation, discoloration, odor, etc.) before and after storage at 0 ° C. for 1 month in normal humidity and the stability judged from these are shown as ◯: good Δ: normal ×: poor.

The above results are shown in Table 2 below.

[0060]

[Table 2]

From Tables 1 and 2, the tri [2-
When (1,3,3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is added to various cosmetics, any of film feeling, body feeling, and state,
It is apparent that a product which is superior to the conventional polyglyceryl polyisostearate having a low viscosity and also has good stability can be obtained.

Further, with respect to the lipsticks of Example 5 and Comparative Example 5, the following four kinds of tests were conducted, and the criteria shown in Table 3
Evaluation was made as Δ or ×, and the results are summarized in Table 4.

Horizontal test: In a constant temperature device at 40, 45 and 50 ° C., in a state where all the lipsticks formed in a shell shape and attached to the container were fed out, 24 hours after being left horizontal,
Visually observe the deformation, that is, the bending and bending.

Penetration test: After molding the lipstick, the mixture was allowed to stand at 25 ° C. for 24 hours and then, using a rheometer (load pressure: 0 to 2 kg) equipped with an adapter having a diameter of 3 mm, T speed of 6 cm / min. Penetration depth 1 cm, stress at 25 ° C (g)
Ask for.

Breaking strength test: A lipstick formed into a shell shape and attached to a container was allowed to stand at 25 ° C. for 24 hours and then fed out, and a rheometer equipped with a tooth-shaped pushing rod as an adapter (load pressure: 0 ~ 2 kg),
The predetermined position is pressed at a T speed of 6 cm / min at 25 ° C., and the stress (g) at breakage is obtained.

Shear strength test: After molding the lipstick, allowed to stand at 25 ° C. for 24 hours, then using a rheometer (load pressure: 0 to 200 g) equipped with a piano wire as an adapter, T speed was set to 2 cm / min. , Shear stress at 25 ℃ (g)
Ask for.

[0067]

[Table 3]

[0068]

[Table 4]

From Table 4, the tri- [2- (1,3,3
It is demonstrated that the lipstick to which 3-trimethyl) butyl-5,7,7-trimethyloctanoic acid] diglyceryl is added has excellent stability, especially at high temperatures.

[0070]

As described above, according to the present invention,
When applied to skin, hair, etc., an excellent film feeling, a cosmetic material that is desired to bring a feeling of use such as richness, that is, make-up, skin care and hair care products, and a raw material compound useful in a skin composition are Provided. When this raw material compound is blended, the feeling of use is improved and the viscosity,
A cosmetic and dermatological composition having excellent stability can be obtained without causing changes in physical properties such as hardness.

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁷ identification code FI theme code (reference) A61K 7/48 A61K 7/48 C07C 69/33 C07C 69/33 (72) Inventor Babaichi Yokaichi, Shiga Prefecture 112-1 Okada-cho, Noevir Shiga Research Institute Ltd. (72) Inventor Nakae Iwakazu 112-1, Okada-cho, Yokaichi City, Shiga Prefecture No-Evia Shiga Research Laboratory F-term (reference) 4C083 AA082 AA122 AB032 AB432 AB442 AC011 AC022 AC072 AC122 AC212 AC242 AC342 AC352 AC372 AC421 AC422 AC442 AC482 AD092 AD152 AD162 AD172 AD332 AD512 AD642 CC05 CC11 CC12 CC13 CC19 DD11 DD17 DD23 DD32 EE01 EE06 EE11 4H006 AA01 AB12 BP10

Claims (9)

[Claims] 1. The following chemical formula (I): [Wherein, 1 to 12 substituents in R are represented by the following chemical formula (II): And the remaining R represents H and n represents an integer of 0 to 8], which is a raw material compound of a cosmetic or dermatological composition, which is polyglyceryl isostearate. 2. The compound according to claim 1, wherein 1 to 4 Rs in the chemical formula (I) are represented by the chemical formula (II). 3. The compound according to claim 1, wherein n is 0 in the chemical formula (I). 4. Tri [2- (1,3,3-trimethyl)]
The compound according to claim 3, which is butyl-5,7,7-trimethyloctanoic acid] diglyceryl. 5. The viscosity at 25 ° C. is 5000 to 350.
It is 00 mPa * s, The compound in any one of Claims 1 thru | or 4. 6. A cosmetic comprising at least one of the raw material compounds according to any one of claims 1 to 5. 7. The cosmetic according to claim 6, which is an emulsion, cream, sunscreen, lipstick composition or powder cosmetic. 8. The cosmetic according to claim 7, which is a composition for lipstick. 9. A skin composition containing at least one or more of the raw material compounds according to any one of claims 1 to 5.