JP2003024010A - Function-enhancing supplementary food comprising as main ingredient green tea catechin - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a function-enhancing supplementary food comprising as the main ingredient green tea catechin. SOLUTION: This supplementary food is a tablet comprising as the main ingredient green tea catechin and as subsidiary ingredients a small amount of garcinia leaf powder, grape seed powder, vitamin B12 , vitamin E, Bacillus natto culture essence and a vehicle with which a quick recovery from fatigue can be expected through effectively removing active oxygen from inside of the body.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a function-enhancing supplementary food containing green tea catechin extracted from tea leaves as a main component, a small amount of an auxiliary medicinal component, a excipient and excipients.

[0002]

2. Description of the Related Art Oxygen is necessary for humans to survive, and humans use oxygen effectively to maintain life, and
It is said to have evolved by having a defense function against active oxygen, which is a harmful component that has changed in the body.
It is said that the oxygen that is breathed by humans every day is activated several thousand times more than usual when oxygen reacts with nutrient components in the human body to generate energy.

[0003]

The human body normally has the ability to remove active oxygen as described above. However, when various causes such as overwork, stress, and unbalanced diets are overlapped, the ability remarkably deteriorates. It may not be possible to eliminate active oxygen by itself.

As a result, cells are destroyed by active oxygen and "oxidative damage" is developed, which causes aging and adult diseases, which is a serious problem. No suitable solution for this problem called "oxygen poisoning" was known. It is an object of the present invention to solve the above-mentioned conventional problems and provide a necessary antioxidant component and a function-enhancing supplement food having an appropriate medicinal effect.

[0005]

[Means for Solving the Problems] In order to achieve the above object, the present inventor has conducted extensive studies, and as a result, has the ability to remove active oxygen required for green tea catechin, which is a tea leaf extract, and aged the human body. They have found that they are also excellent in prevention, and have completed the present invention.

The present invention made based on the above findings is
A functional-enhancing supplement, which is mainly composed of green tea catechin and a small amount of garcinia leaf powder, grape seed powder, vitamin B ₁₂ , vitamin E, Bacillus natto culture extract and excipients as accessory components. There is.

Further, the gist of the present invention is that the green tea catechin is a tea leaf extract containing 75% or more of polyphenols, and the above-mentioned function-enhancing supplement foods whose excipients are red ball dextrin, lactose and sugar ester. is there.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION The structure and operation of the present invention will be described.
The main constituent of the functional supplement of the present invention is tea leaf extract, which is green tea catechin having a polyphenol content of 75% or more. This green tea catechin is a powerful antioxidant enzyme (SO
It has D) -like activity, and it is difficult to ingest an SOD-like substance equivalent to or better than the product of the present invention from other foods.

The effects of such green tea polyphenols (catechins) are known to be oral hygiene, improvement of intestinal environment, and in vivo antioxidant (“F00D Style 2”).
1 ”2000.1 [Vol. 4 No. 1] P45 ~
51, "ILSI" No. 65 [2000, 12]
P14-22, CMC [Published May 31, 1996] "Development of new food functional ingredients" P210-22
3, and J. Agric. Food Chem.
1999, Vol. 47, No. 10 P3967-3
As a food additive, for example, Sanphenon DCF-1 (trade name: manufactured by Taiyo Kagaku Co., Ltd.) and the like are commercially available.

The mixing ratio is 20.00 to 3 in the supplement.
0.00% (% by weight, the same applies hereinafter), 20.00%
If it is less than the above, the strong antioxidant enzyme (SOD) -like activity of green tea catechin cannot be sufficiently exhibited. Further, if it exceeds 30.00%, the harmony with other components is lost, which is not preferable. More preferably, the proportion of 23.00 to 27.00% is good, and 2
Around 5.00% is the most effective.

Garcinia leaf powder added to the function-enhancing supplement of the present invention is made from leaves of four kinds of Garcinia genus trees that grow in the tropics. Among them, the synthesis of glucose into fat in the human body is performed. It contains natural (-) HCA (hydroxycitric acid) to suppress (see "Development of New Food Functional Ingredients" P331 to 336). The Garcinia leaf powder is commercially available, for example, Garcinia leaf M (trade name: manufactured by Seimitsu Pharmaceutical Co., Ltd.).

The action of HCA suppresses the production of cholesterol in the body, and is effective in preventing obesity and lowering cholesterol, which cause adult diseases. In addition, it has a high SOD scavenging activity and abundant dietary fiber is included, which acts synergistically to maintain health. The blending ratio is 0.10 to 1.00%, preferably 0.
It is 30 to 0.70%.

Similarly, the seeds of grape added to the function-enhancing supplement of the present invention contain proanthocyanidin, which is a kind of polyphenol ("Food and Development" Vol. 31 No. 10 P8-9). , "Development of Functional Materials for New Foods", p. 369-374). It has been confirmed that this component exhibits high antioxidant power. A commercially available product of grape seed powder is KPA-40 (trade name: manufactured by Kikkoman Corporation), which has a strong action of removing free radicals and active oxygen, which have been pointed out as important causes of adult diseases and aging. It has been reported to be effective in preventing arteriosclerosis, improving capillary resistance, improving varicose veins in the lower extremities, and improving visual acuity. The blending amount is 0.05 to 0.500%, and the effect is exhibited at a blending amount of 0.10%.

Vitamin B ₁₂ used in the present invention
Is called a hematopoietic vitamin, and is known to have an effect of acting on the production of red blood cells and white blood cells, phospholipid synthesis and nucleic acid synthesis, participating in protein biosynthesis, and assisting the correct functioning of the nervous system. Due to lack, symptoms such as weakened immunity, arteriosclerosis, neuralgia, arthritis, and eye strain appear. The blending amount is 0.01 to 0.05%.

Further, vitamin E acts as an antioxidant to prevent the oxidation of unsaturated fatty acids in biological membranes and protect cells.
Luteinizing hormone, male hormone, involved in the generation secretion of steroid hormones, help folic acid, the action of vitamin B _12,
It works on hematopoiesis and keeps red blood cells healthy. It has the effects of preventing blood clots, extending the vitality of cells, and maintaining reproductive function. Due to lack, symptoms such as arteriosclerosis, angina, myocardial infarction, liver damage, and diabetes may appear. The amount is 3.00 to 8.00%, is adjusted in accordance with the amount of vitamin _{B 12.}

The natto culture extract used in the present invention contains nattokinase having a thrombolytic action.
Examples of commercially available products include Bioteam NSK (trade name:
Japan Bio Science Laborat
ory). The blending amount is preferably 0.05 to 1.00%, and even at 0.10%, the effect is sufficiently exhibited.

In the present invention, the above-mentioned respective raw material components are blended in predetermined amounts, and akadama dextrin, lactose and sugar ester are added as excipients to these, and they are sufficiently stirred and mixed at low temperature and under dry conditions, The mixture is tabletted on the tablet press used in the tablet industry in the pharmaceutical industry. The composition of Akatama dextrin is 7 to 12%. If it is less than 7%, the tablet strength is insufficient, and if it exceeds 12%, the disintegration property when taken is lowered. Sugar ester has the role of lubricant in tablet manufacture. 1.00 to 3.00% is a preferable range. If it is less than 1.00%, the effect is insufficient, and if it exceeds 3.00%, it is not economical.

The balance of each component blended as described above is lactose, and usually has a main role of shaping in the case of tablet type health supplement. Lactose is contained in the milky secretions of mammals and is about 16% sweeter than sucrose.

The size of the tablets formed varies depending on the proportion of green tea catechin contained, but as a standard, the weight of one tablet is 370 mg, the central tablet thickness is 4.6 mm, the peripheral thickness is 2.0 mm, and the diameter is 6 The shape is a swelling shape of 0.8 mm, but the shape is not limited to this, and other shapes may be used, and the surface of the tablet is coated with shellac for easy administration. If necessary, sugar coating may be applied.

The following Table 1 shows an example of a specific formulation of the function-enhancing supplement of the present invention. The shape and dimensions of one tablet were the standard ones described above.

[0021] Male and female volunteers of each age group who are engaged in ordinary occupations are supplemented with the supplement of the present invention for enhancing the function of the present invention 2.
Tables 2 to 5 show the results of an investigation of fatigue recovery (improvement of fatigue) by taking 0 people. The effects exhibited by 2/3 or more persons were classified into four ranks: A: prompt recovery, B: normal recovery, C: slow recovery, D: no effect. The degree of effect was indicated by the number of symbols.

[0022]

[0023]

[0024]

[0025]

From the results of the test, it is said that the older the generation of active oxygen is, the more active oxygen is produced in the blood by taking the function-enhancing supplement of the present invention. It was confirmed that it was particularly effective in recovering from fatigue.

[0027]

EFFECTS OF THE INVENTION Since the present invention is constituted as described above, it is possible to expect prompt recovery from fatigue by effectively removing active oxygen in the body, which is not expected to have a sufficient effect from a normal diet. It is useful for promotion and extremely useful in the food industry.

Claims (5)

[Claims] 1. A functional enhancement comprising green tea catechin as a main component and a small amount of garcinia leaf powder, grape seed powder, vitamin B ₁₂ , vitamin E, natto bacterium culture extract and an excipient as accessory components. Supplements. 2. The function-enhancing supplement according to claim 1, wherein the green tea catechin is a tea leaf extract containing at least 75% polyphenol. 3. Green tea catechin: 20.00 to 30.00
% (Weight%, the same below), Garcinia leaf powder: 0.10.
~ 1.00%, grape seed powder: 0.05-0.50
%, Vitamin B ₁₂ : 0.01 to 0.05%, Vitamin E: 3.00 to 8.00%, Bacillus natto culture extract: 0.0
The function-enhancing supplement according to claim 1 or 2, wherein 5 to 1.00% is the balance excipient. 4. The function-enhancing supplement food according to claim 1, 2 or 3, wherein the excipient comprises red ball dextrin, lactose and sugar ester. 5. The excipient is Akadama dextrin: 7.00
12.00%, sugar ester: 1.00 to 3.00
%, The balance being lactose, The function-enhancing supplement according to claim 4.